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Volumn 22, Issue 3, 2016, Pages 288-297

Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9

Author keywords

[No Author keywords available]

Indexed keywords

CALGRANULIN A; CALGRANULIN B; PROTEIN P53; RIBOSOMAL PROTEIN SUBUNIT 14; RIBOSOME PROTEIN; UNCLASSIFIED DRUG; CYTOKINE; RIBOSOMAL PROTEIN S14; S100A8 PROTEIN, MOUSE; S100A9 PROTEIN, MOUSE;

EID: 84958078801     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.4047     Document Type: Article
Times cited : (197)

References (60)
  • 1
    • 67650859652 scopus 로고    scopus 로고
    • Deletion 5q in myelodysplastic syndrome: A paradigm for the study of hemizygous deletions in cancer
    • Ebert B.L. Deletion 5q in myelodysplastic syndrome: a paradigm for the study of hemizygous deletions in cancer. Leukemia 23, 1252-1256 (2009).
    • (2009) Leukemia , vol.23 , pp. 1252-1256
    • Ebert, B.L.1
  • 2
    • 80053198659 scopus 로고    scopus 로고
    • Molecular dissection of the 5q deletion in myelodysplastic syndrome
    • Ebert B.L. Molecular dissection of the 5q deletion in myelodysplastic syndrome. Semin. Oncol. 38, 621-626 (2011).
    • (2011) Semin. Oncol. , vol.38 , pp. 621-626
    • Ebert, B.L.1
  • 4
    • 38349088899 scopus 로고    scopus 로고
    • Identification of RPS14 as a 5q- syndrome gene by RNA interference screen
    • Ebert B.L, et al. Identification of RPS14 as a 5q- syndrome gene by RNA interference screen. Nature 451, 335-339 (2008).
    • (2008) Nature , vol.451 , pp. 335-339
    • Ebert, B.L.1
  • 5
    • 33846873892 scopus 로고    scopus 로고
    • Impaired ribosome biogenesis in Diamond-Blackfan anemia
    • Choesmel V, et al. Impaired ribosome biogenesis in Diamond-Blackfan anemia. Blood 109, 1275-1283 (2007).
    • (2007) Blood , vol.109 , pp. 1275-1283
    • Choesmel, V.1
  • 6
    • 84908577172 scopus 로고    scopus 로고
    • Marrow failure: A window into ribosome biology
    • Ruggero D, & Shimamura A. Marrow failure: a window into ribosome biology. Blood 124, 2784-2792 (2014).
    • (2014) Blood , vol.124 , pp. 2784-2792
    • Ruggero, D.1    Shimamura, A.2
  • 7
    • 48249117726 scopus 로고    scopus 로고
    • Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects
    • McGowan K.A, et al. Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects. Nat. Genet. 40, 963-970 (2008).
    • (2008) Nat. Genet. , vol.40 , pp. 963-970
    • McGowan, K.A.1
  • 8
    • 80053358313 scopus 로고    scopus 로고
    • Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome
    • McGowan K.A, et al. Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome. Blood 118, 3622-3633 (2011).
    • (2011) Blood , vol.118 , pp. 3622-3633
    • McGowan, K.A.1
  • 9
    • 33645282549 scopus 로고    scopus 로고
    • Erythropoiesis in the Rps19-disrupted mouse: Analysis of erythropoietin response and biochemical markers for Diamond-Blackfan anemia
    • Matsson H, et al. Erythropoiesis in the Rps19-disrupted mouse: analysis of erythropoietin response and biochemical markers for Diamond-Blackfan anemia. Blood Cells Mol. Dis. 36, 259-264 (2006).
    • (2006) Blood Cells Mol. Dis. , vol.36 , pp. 259-264
    • Matsson, H.1
  • 10
    • 79953117045 scopus 로고    scopus 로고
    • Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells
    • Dutt S, et al. Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells. Blood 117, 2567-2576 (2011).
    • (2011) Blood , vol.117 , pp. 2567-2576
    • Dutt, S.1
  • 11
    • 77950988337 scopus 로고    scopus 로고
    • Induction of p53 and upregulation of the p53 pathway in the human 5q- syndrome
    • Pellagatti A, et al. Induction of p53 and upregulation of the p53 pathway in the human 5q- syndrome. Blood 115, 2721-2723 (2010).
    • (2010) Blood , vol.115 , pp. 2721-2723
    • Pellagatti, A.1
  • 12
    • 84872619062 scopus 로고    scopus 로고
    • Ribosomal protein S14 unties the MDM2-p53 loop upon ribosomal stress
    • Zhou X, Hao Q, Liao J, Zhang Q, & Lu H. Ribosomal protein S14 unties the MDM2-p53 loop upon ribosomal stress. Oncogene 32, 388-396 (2013).
    • (2013) Oncogene , vol.32 , pp. 388-396
    • Zhou, X.1    Hao, Q.2    Liao, J.3    Zhang, Q.4    Lu, H.5
  • 13
    • 73849128091 scopus 로고    scopus 로고
    • A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome
    • Barlow J.L, et al. A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome. Nat. Med. 16, 59-66 (2010).
    • (2010) Nat. Med. , vol.16 , pp. 59-66
    • Barlow, J.L.1
  • 14
    • 84894419714 scopus 로고    scopus 로고
    • The emerging importance of ribosomal dysfunction in the pathogenesis of hematologic disorders
    • Raiser D.M, Narla A, & Ebert B.L. The emerging importance of ribosomal dysfunction in the pathogenesis of hematologic disorders. Leuk. Lymphoma 55, 491-500 (2014).
    • (2014) Leuk. Lymphoma , vol.55 , pp. 491-500
    • Raiser, D.M.1    Narla, A.2    Ebert, B.L.3
  • 15
    • 0034674714 scopus 로고    scopus 로고
    • Proliferation but not growth blocked by conditional deletion of 40S ribosomal protein S6
    • Volarevic S, et al. Proliferation but not growth blocked by conditional deletion of 40S ribosomal protein S6. Science 288, 2045-2047 (2000).
    • (2000) Science , vol.288 , pp. 2045-2047
    • Volarevic, S.1
  • 17
    • 84055200841 scopus 로고    scopus 로고
    • Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age
    • Pang W.W, et al. Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age. Proc. Natl. Acad. Sci. USA 108, 20012-20017 (2011).
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 20012-20017
    • Pang, W.W.1
  • 18
    • 84883325165 scopus 로고    scopus 로고
    • Inflammation-mediated notch signaling skews Fanconi anemia hematopoietic stem cell differentiation
    • Du W, et al. Inflammation-mediated notch signaling skews Fanconi anemia hematopoietic stem cell differentiation. J. Immunol. 191, 2806-2817 (2013).
    • (2013) J. Immunol. , vol.191 , pp. 2806-2817
    • Du, W.1
  • 19
    • 84898739668 scopus 로고    scopus 로고
    • Haematopoietic stem cells require a highly regulated protein synthesis rate
    • Signer R.A, Magee J.A, Salic A, & Morrison S.J. Haematopoietic stem cells require a highly regulated protein synthesis rate. Nature 509, 49-54 (2014).
    • (2014) Nature , vol.509 , pp. 49-54
    • Signer, R.A.1    Magee, J.A.2    Salic, A.3    Morrison, S.J.4
  • 20
    • 73049147765 scopus 로고
    • A kinetic model of the erythron
    • Lajtha L.G, & Oliver R. A kinetic model of the erythron. Proc. R. Soc. Med. 54, 369-371 (1961).
    • (1961) Proc. R. Soc. Med. , vol.54 , pp. 369-371
    • Lajtha, L.G.1    Oliver, R.2
  • 21
    • 80053576895 scopus 로고    scopus 로고
    • Inside the 40S ribosome assembly machinery
    • Karbstein K. Inside the 40S ribosome assembly machinery. Curr. Opin. Chem. Biol. 15, 657-663 (2011).
    • (2011) Curr. Opin. Chem. Biol. , vol.15 , pp. 657-663
    • Karbstein, K.1
  • 22
    • 73249132431 scopus 로고    scopus 로고
    • Powering through ribosome assembly
    • Strunk B.S, & Karbstein K. Powering through ribosome assembly. RNA 15, 2083-2104 (2009).
    • (2009) RNA , vol.15 , pp. 2083-2104
    • Strunk, B.S.1    Karbstein, K.2
  • 23
    • 81155159831 scopus 로고    scopus 로고
    • Ribosome assembly factors prevent premature translation initiation by 40S assembly intermediates
    • Strunk B.S, et al. Ribosome assembly factors prevent premature translation initiation by 40S assembly intermediates. Science 333, 1449-1453 (2011).
    • (2011) Science , vol.333 , pp. 1449-1453
    • Strunk, B.S.1
  • 24
    • 84887430236 scopus 로고    scopus 로고
    • Induction of myelodysplasia by myeloid-derived suppressor cells
    • Chen X, et al. Induction of myelodysplasia by myeloid-derived suppressor cells. J. Clin. Invest. 123, 4595-4611 (2013).
    • (2013) J. Clin. Invest. , vol.123 , pp. 4595-4611
    • Chen, X.1
  • 25
    • 73849121794 scopus 로고    scopus 로고
    • Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype
    • Starczynowski D.T, et al. Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype. Nat. Med. 16, 49-58 (2010).
    • (2010) Nat. Med. , vol.16 , pp. 49-58
    • Starczynowski, D.T.1
  • 27
    • 70149117029 scopus 로고    scopus 로고
    • A novel p53 target gene, S100A9, induces p53-dependent cellular apoptosis and mediates the p53 apoptosis pathway
    • Li C, et al. A novel p53 target gene, S100A9, induces p53-dependent cellular apoptosis and mediates the p53 apoptosis pathway. Biochem. J. 422, 363-372 (2009).
    • (2009) Biochem. J. , vol.422 , pp. 363-372
    • Li, C.1
  • 28
    • 0032979422 scopus 로고    scopus 로고
    • Transcriptional activation of the human S100A2 promoter by wild-Type p53
    • Tan M, Heizmann C.W, Guan K, Schafer B.W, & Sun Y. Transcriptional activation of the human S100A2 promoter by wild-Type p53. FEBS Lett. 445, 265-268 (1999).
    • (1999) FEBS Lett. , vol.445 , pp. 265-268
    • Tan, M.1    Heizmann, C.W.2    Guan, K.3    Schafer, B.W.4    Sun, Y.5
  • 29
    • 23844505646 scopus 로고    scopus 로고
    • The calcium-binding protein S100A2 interacts with p53 and modulates its transcriptional activity
    • Mueller A, et al. The calcium-binding protein S100A2 interacts with p53 and modulates its transcriptional activity. J. Biol. Chem. 280, 29186-29193 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 29186-29193
    • Mueller, A.1
  • 30
    • 33751504690 scopus 로고    scopus 로고
    • Tumor-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
    • Hiratsuka S, Watanabe A, Aburatani H, & Maru Y. Tumor-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nat. Cell Biol. 8, 1369-1375 (2006).
    • (2006) Nat. Cell Biol. , vol.8 , pp. 1369-1375
    • Hiratsuka, S.1    Watanabe, A.2    Aburatani, H.3    Maru, Y.4
  • 31
    • 84919623453 scopus 로고    scopus 로고
    • TNF-mediated inflammation represses GATA1 and activates p38 MAP kinase in RPS19-deficient hematopoietic progenitors
    • Bibikova E, et al. TNF-mediated inflammation represses GATA1 and activates p38 MAP kinase in RPS19-deficient hematopoietic progenitors. Blood 124, 3791-3798 (2014).
    • (2014) Blood , vol.124 , pp. 3791-3798
    • Bibikova, E.1
  • 32
    • 84884164883 scopus 로고    scopus 로고
    • Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche
    • Schepers K, et al. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. Cell Stem Cell 13, 285-299 (2013).
    • (2013) Cell Stem Cell , vol.13 , pp. 285-299
    • Schepers, K.1
  • 33
    • 61849168098 scopus 로고    scopus 로고
    • IL-17-producing CD4+ T cells, pro-inflammatory cytokines and apoptosis are increased in low-risk myelodysplastic syndrome
    • Kordasti S.Y, et al. IL-17-producing CD4+ T cells, pro-inflammatory cytokines and apoptosis are increased in low-risk myelodysplastic syndrome. Br. J. Haematol. 145, 64-72 (2009).
    • (2009) Br. J. Haematol. , vol.145 , pp. 64-72
    • Kordasti, S.Y.1
  • 34
    • 0030806967 scopus 로고    scopus 로고
    • Inhibition of immature erythroid progenitor cell proliferation by macrophage inflammatory protein-1? by interacting mainly with a C-C chemokine receptor, CCR1
    • Su S, et al. Inhibition of immature erythroid progenitor cell proliferation by macrophage inflammatory protein-1? by interacting mainly with a C-C chemokine receptor, CCR1. Blood 90, 605-611 (1997).
    • (1997) Blood , vol.90 , pp. 605-611
    • Su, S.1
  • 35
    • 84855858755 scopus 로고    scopus 로고
    • Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia
    • Frisch B.J, et al. Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia. Blood 119, 540-550 (2012).
    • (2012) Blood , vol.119 , pp. 540-550
    • Frisch, B.J.1
  • 36
    • 34948900275 scopus 로고    scopus 로고
    • Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock
    • Vogl T, et al. Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock. Nat. Med. 13, 1042-1049 (2007).
    • (2007) Nat. Med. , vol.13 , pp. 1042-1049
    • Vogl, T.1
  • 37
    • 67649208478 scopus 로고    scopus 로고
    • The endogenous Toll-like receptor 4 agonist S100A8-S100A9 (calprotectin) as an innate amplifier of infection, autoimmunity and cancer
    • Ehrchen J.M, Sunderkötter C, Foell D, Vogl T, & Roth J. The endogenous Toll-like receptor 4 agonist S100A8-S100A9 (calprotectin) as an innate amplifier of infection, autoimmunity and cancer. J. Leukoc. Biol. 86, 557-566 (2009).
    • (2009) J. Leukoc. Biol. , vol.86 , pp. 557-566
    • Ehrchen, J.M.1    Sunderkötter, C.2    Foell, D.3    Vogl, T.4    Roth, J.5
  • 38
    • 84887322071 scopus 로고    scopus 로고
    • Global H3K4me3 genome mapping reveals alterations of innate immunity signaling and overexpression of JMJD3 in human myelodysplastic syndrome CD34+ cells
    • Wei Y, et al. Global H3K4me3 genome mapping reveals alterations of innate immunity signaling and overexpression of JMJD3 in human myelodysplastic syndrome CD34+ cells. Leukemia 27, 2177-2186 (2013).
    • (2013) Leukemia , vol.27 , pp. 2177-2186
    • Wei, Y.1
  • 39
    • 84919847558 scopus 로고    scopus 로고
    • P62 is required for stem cell-progenitor retention through inhibition of IKK-NF-?B-Ccl4 signaling at the bone marrow macrophage-osteoblast niche
    • Chang K.H, et al. p62 is required for stem cell-progenitor retention through inhibition of IKK-NF-?B-Ccl4 signaling at the bone marrow macrophage-osteoblast niche. Cell Rep. 9, 2084-2097 (2014).
    • (2014) Cell Rep. , vol.9 , pp. 2084-2097
    • Chang, K.H.1
  • 40
    • 77953504215 scopus 로고    scopus 로고
    • Deregulation of innate immune signaling in myelodysplastic syndromes is associated with deletion of chromosome arm 5q
    • Starczynowski D.T, & Karsan A. Deregulation of innate immune signaling in myelodysplastic syndromes is associated with deletion of chromosome arm 5q. Cell Cycle 9, 855-856 (2010).
    • (2010) Cell Cycle , vol.9 , pp. 855-856
    • Starczynowski, D.T.1    Karsan, A.2
  • 41
    • 80053389114 scopus 로고    scopus 로고
    • TRAF6 is an amplified oncogene bridging the RAS and NF-?B pathways in human lung cancer
    • Starczynowski D.T, et al. TRAF6 is an amplified oncogene bridging the RAS and NF-?B pathways in human lung cancer. J. Clin. Invest. 121, 4095-4105 (2011).
    • (2011) J. Clin. Invest. , vol.121 , pp. 4095-4105
    • Starczynowski, D.T.1
  • 42
    • 81255189474 scopus 로고    scopus 로고
    • IL-6 controls leukemic multipotent progenitor cell fate and contributes to chronic myelogenous leukemia development
    • Reynaud D, et al. IL-6 controls leukemic multipotent progenitor cell fate and contributes to chronic myelogenous leukemia development. Cancer Cell 20, 661-673 (2011).
    • (2011) Cancer Cell , vol.20 , pp. 661-673
    • Reynaud, D.1
  • 43
    • 84880002232 scopus 로고    scopus 로고
    • Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome
    • Rhyasen G.W, et al. Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome. Cancer Cell 24, 90-104 (2013).
    • (2013) Cancer Cell , vol.24 , pp. 90-104
    • Rhyasen, G.W.1
  • 44
    • 79960709287 scopus 로고    scopus 로고
    • Chronic immune stimulation might act as a trigger for the development of acute myeloid leukemia or myelodysplastic syndromes
    • Kristinsson S.Y, et al. Chronic immune stimulation might act as a trigger for the development of acute myeloid leukemia or myelodysplastic syndromes. J. Clin. Oncol. 29, 2897-2903 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , pp. 2897-2903
    • Kristinsson, S.Y.1
  • 45
    • 84859181084 scopus 로고    scopus 로고
    • Demand-Adapted regulation of early hematopoiesis in infection and inflammation
    • Takizawa H, Boettcher S, & Manz M.G. Demand-Adapted regulation of early hematopoiesis in infection and inflammation. Blood 119, 2991-3002 (2012).
    • (2012) Blood , vol.119 , pp. 2991-3002
    • Takizawa, H.1    Boettcher, S.2    Manz, M.G.3
  • 46
    • 84875658458 scopus 로고    scopus 로고
    • Blood CD33+HLA-DR? Myeloid-derived suppressor cells are increased with age and a history of cancer
    • Verschoor C.P, et al. Blood CD33+HLA-DR? myeloid-derived suppressor cells are increased with age and a history of cancer. J. Leukoc. Biol. 93, 633-637 (2013).
    • (2013) J. Leukoc. Biol. , vol.93 , pp. 633-637
    • Verschoor, C.P.1
  • 47
    • 77950862042 scopus 로고    scopus 로고
    • Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
    • Raaijmakers M.H, et al. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature 464, 852-857 (2010).
    • (2010) Nature , vol.464 , pp. 852-857
    • Raaijmakers, M.H.1
  • 48
    • 84864495501 scopus 로고    scopus 로고
    • Cytotoxic effects of bortezomib in myelodysplastic syndrome-Acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1
    • Fang J, et al. Cytotoxic effects of bortezomib in myelodysplastic syndrome-Acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1. Blood 120, 858-867 (2012).
    • (2012) Blood , vol.120 , pp. 858-867
    • Fang, J.1
  • 49
    • 34250007142 scopus 로고    scopus 로고
    • Deficiencies in DNA damage repair limit the function of hematopoietic stem cells with age
    • Rossi D.J, et al. Deficiencies in DNA damage repair limit the function of hematopoietic stem cells with age. Nature 447, 725-729 (2007).
    • (2007) Nature , vol.447 , pp. 725-729
    • Rossi, D.J.1
  • 50
    • 0028891726 scopus 로고
    • Pathogenesis of the anemia of chronic disease: A cytokine-mediated anemia
    • Means R.T. Jr. Pathogenesis of the anemia of chronic disease: a cytokine-mediated anemia. Stem Cells 13, 32-37 (1995).
    • (1995) Stem Cells , vol.13 , pp. 32-37
    • Means, R.T.1
  • 51
    • 0037411227 scopus 로고    scopus 로고
    • Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes
    • Sawanobori M, et al. Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes. Leuk. Res. 27, 583-591 (2003).
    • (2003) Leuk. Res. , vol.27 , pp. 583-591
    • Sawanobori, M.1
  • 52
    • 0037438503 scopus 로고    scopus 로고
    • Tumor necrosis factor-Alpha expressed constitutively in erythroid cells or induced by erythropoietin has negative and stimulatory roles in normal erythropoiesis and erythroleukemia
    • Jacobs-Helber S.M, et al. Tumor necrosis factor-Alpha expressed constitutively in erythroid cells or induced by erythropoietin has negative and stimulatory roles in normal erythropoiesis and erythroleukemia. Blood 101, 524-531 (2003).
    • (2003) Blood , vol.101 , pp. 524-531
    • Jacobs-Helber, S.M.1
  • 53
    • 79951812916 scopus 로고    scopus 로고
    • Telomere dysfunction induces metabolic and mitochondrial compromise
    • Sahin E, et al. Telomere dysfunction induces metabolic and mitochondrial compromise. Nature 470, 359-365 (2011).
    • (2011) Nature , vol.470 , pp. 359-365
    • Sahin, E.1
  • 54
    • 84908006668 scopus 로고    scopus 로고
    • Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS
    • Schneider R.K, et al. Role of casein kinase 1A1 in the biology and targeted therapy of del(5q) MDS. Cancer Cell 26, 509-520 (2014).
    • (2014) Cancer Cell , vol.26 , pp. 509-520
    • Schneider, R.K.1
  • 55
    • 34547477270 scopus 로고    scopus 로고
    • In vitro erythropoiesis from bone marrow-derived progenitors provides a physiological assay for toxic and mutagenic compounds
    • Shuga J, Zhang J, Samson L.D, Lodish H.F, & Griffith L.G. In vitro erythropoiesis from bone marrow-derived progenitors provides a physiological assay for toxic and mutagenic compounds. Proc. Natl. Acad. Sci. USA 104, 8737-8742 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 8737-8742
    • Shuga, J.1    Zhang, J.2    Samson, L.D.3    Lodish, H.F.4    Griffith, L.G.5
  • 56
    • 84897541015 scopus 로고    scopus 로고
    • Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110-?
    • Gritsman K, et al. Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110-?. J. Clin. Invest. 124, 1794-1809 (2014).
    • (2014) J. Clin. Invest. , vol.124 , pp. 1794-1809
    • Gritsman, K.1
  • 57
    • 84879637572 scopus 로고    scopus 로고
    • Integrated proteomic analysis of post-Translational modifications by serial enrichment
    • Mertins P, et al. Integrated proteomic analysis of post-Translational modifications by serial enrichment. Nat. Methods 10, 634-637 (2013).
    • (2013) Nat. Methods , vol.10 , pp. 634-637
    • Mertins, P.1
  • 58
    • 84892680505 scopus 로고    scopus 로고
    • Analysis of the topology of protein complexes using cross-linking and mass spectrometry
    • Rappsilber J, & Mann M. Analysis of the topology of protein complexes using cross-linking and mass spectrometry. Cold Spring Harb. Protoc. doi: 10.1101/pdb.prot4594 (2007).
    • (2007) Cold Spring Harb. Protoc
    • Rappsilber, J.1    Mann, M.2
  • 59
    • 37849021555 scopus 로고    scopus 로고
    • Telomere-length analysis in monocytes and lymphocytes from patients with systemic lupus erythematosus using multicolor flow-FISH
    • Beier F, et al. Telomere-length analysis in monocytes and lymphocytes from patients with systemic lupus erythematosus using multicolor flow-FISH. Lupus 16, 955-962 (2007).
    • (2007) Lupus , vol.16 , pp. 955-962
    • Beier, F.1
  • 60
    • 22144437035 scopus 로고    scopus 로고
    • Accelerated telomere shortening in glycosylphosphatidylinositol (GPI)-negative compared with GPI-positive granulocytes from patients with paroxysmal nocturnal hemoglobinuria (PNH) detected by proaerolysin flow-FISH
    • Beier F, et al. Accelerated telomere shortening in glycosylphosphatidylinositol (GPI)-negative compared with GPI-positive granulocytes from patients with paroxysmal nocturnal hemoglobinuria (PNH) detected by proaerolysin flow-FISH. Blood 106, 531-533 (2005).
    • (2005) Blood , vol.106 , pp. 531-533
    • Beier, F.1


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