Current Updates on Classification, Diagnosis and Treatment of Hemophagocytic Lymphohistiocytosis (HLH)

Indian Journal of Pediatrics

Volumn 83, Issue 5, 2016, Pages 434-443

  Madkaikar, Manisha ^a   Shabrish, Snehal ^a   Desai, Mukesh ^b  

^a NATIONAL INSTITUTE OF IMMUNOHAEMATOLOGY   (India)

^b B J WADIA HOSPITAL FOR CHILDREN   (India)

Author keywords

Familial HLH (FHL); Hemophagocytic lymphohistiocytosis (HLH); NK cells; Pathophysiology

Indexed keywords

ALEMTUZUMAB; BLOCKING ANTIBODY; CYCLOSPORIN; DEXAMETHASONE; ETOPOSIDE; FERRITIN; GAMMA INTERFERON; GAMMA INTERFERON ANTIBODY; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMOGLOBIN; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; RITUXIMAB; SIGNALING LYMPHOCYTE ACTIVATION MOLECULE ASSOCIATED PROTEIN; THYMOCYTE ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; X LINKED INHIBITOR OF APOPTOSIS;

ABDUCENS NERVE PARALYSIS; ACQUIRED HEMOPHAGOCYTIC SYNDROME; ATAXIA; BLINDNESS; BLOOD CLOTTING DISORDER; BONE MARROW BIOPSY; CHEDIAK HIGASHI SYNDROME; CLINICAL FEATURE; CLINICAL TRIAL (TOPIC); CONVULSION; CRANIAL NERVE PARALYSIS; CYTOPENIA; CYTOTOXIC T LYMPHOCYTE; DISEASE CLASSIFICATION; FACIAL NERVE PARALYSIS; FAMILIAL HEMOPHAGOCYTIC SYNDROME WITH HYPOPIGMENTATION; FAMILIAL HEMOPHAGOCYTIC SYNDROME WITHOUT HYPOPIGMENTATION; FEVER; GENE MUTATION; GRISCELLI SYNDROME; HEMIPLEGIA; HEMOGLOBIN BLOOD LEVEL; HEMOPHAGOCYTIC SYNDROME; HEPATOSPLENOMEGALY; HERMANSKY PUDLAK SYNDROME 2; HUMAN; HYPERTRIGLYCERIDEMIA; HYPOFIBRINOGENEMIA; INCIDENCE; INNATE IMMUNITY; INTRACRANIAL PRESSURE; LIVER DYSFUNCTION; LYMPHADENOPATHY; LYMPHOPROLIFERATIVE DISEASE; MOLECULAR DIAGNOSIS; MUSCLE HYPERTONIA; MUSCLE HYPOTONIA; NATURAL KILLER CELL; NEUROLOGIC DISEASE; NEUTROPHIL COUNT; OCULAR ALBINISM; PATHOPHYSIOLOGY; QUADRIPLEGIA; RASH; REVIEW; SEIZURE; SPLENOMEGALY; TURKEY (REPUBLIC); UNCONSCIOUSNESS; X CHROMOSOME LINKED DISORDER; X LINKED LYMPHOPROLIFERATIVE SYNDROME; CLASSIFICATION; DISEASE MANAGEMENT; EARLY DIAGNOSIS; GENETIC SCREENING; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNOLOGICAL PROCEDURES; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; PROCEDURES; SECONDARY PREVENTION;

DISEASE MANAGEMENT; EARLY DIAGNOSIS; GENETIC TESTING; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNOLOGIC TESTS; IMMUNOSUPPRESSION; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; SECONDARY PREVENTION;

EID: 84957969030     PISSN: 00195456     EISSN: 09737693     Source Type: Journal    
DOI: 10.1007/s12098-016-2037-y     Document Type: Review

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