Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway

Phytomedicine

Volumn 23, Issue 2, 2016, Pages 114-122

  Zhao, Lijuan ^a   Wen, Qing ^a   Yang, Guotao ^b   Huang, Zhuqing ^a   Shen, Tao ^a   Li, Haizhen ^a   Ren, Dongmei ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Brucea javanica; Dehydrobruceine B; Mitochondrial pathway; Pro apoptotic action

Indexed keywords

ANTINEOPLASTIC AGENT; APOPTOSIS INDUCING FACTOR; BRUCEA JAVANICA EXTRACT; CASPASE 3; CASPASE 9; CYTOCHROME C; DEHYDROBRUCEINE B; MATRIX METALLOPROTEINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; QUASSINOID DERIVATIVE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; CASP3 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN;

A549 CELL LINE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BRUCEA; BRUCEA JAVANICA; CANCER INHIBITION; CELL CYCLE; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOSOL; DRUG ISOLATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME RELEASE; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; INTRINSIC ACTIVITY; LUNG CANCER CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; MTT ASSAY; NCI H292 CELL LINE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; S PHASE CELL CYCLE CHECKPOINT; CELL SURVIVAL; CHEMISTRY; CHINA; DRUG EFFECTS; LUNG TUMOR; METABOLISM; MITOCHONDRION; PATHOLOGY; TUMOR CELL LINE;

APOPTOSIS; CASPASE 3; CASPASE 9; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; CHINA; CYTOCHROMES C; HUMANS; LUNG NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; POLY(ADP-RIBOSE) POLYMERASES; QUASSINS;

EID: 84957942466     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2015.12.019     Document Type: Article

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