Mechanism of arctigenin-mediated specific cytotoxicity against human lung adenocarcinoma cell lines

Phytomedicine

Volumn 21, Issue 1, 2013, Pages 39-46

  Susanti, Siti ^a,b,c   Iwasaki, Hironori ^b   Inafuku, Masashi ^b   Taira, Naoyuki ^a,b   Oku, Hirosuke ^b  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b UNIVERSITY OF THE RYUKYUS   (Japan)

^c DIPONEGORO UNIVERSITY   (Indonesia)

Author keywords

Arctigenin (ARG); Cytotoxicity; Mechanism; Specific

Indexed keywords

ARCTIGENIN; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 7; CYCLIN E; CYCLIN H; LIGASE INHIBITOR; PROTEIN KINASE B;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL SPECIFICITY; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG MECHANISM; HUMAN; LUNG ADENOCARCINOMA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ARCTIUM LAPPA;

AKT-1; ALPHA SERINE/THREONINE-PROTEIN KINASE; ARCTIGENIN; ARCTIGENIN (ARG); ARG; CDK2; CDK7; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 7; CYTOTOXICITY; G(0)/G(1); GAP 0/GAP 1; GLUTATHIONE; GSH; MECHANISM; NPAT; NUCLEAR PROTEIN OF THE ATAXIA TELANGIECTASIA LOCUS; SPECIFIC;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; ARCTIUM; CELL CYCLE PROTEINS; CELL LINE; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLINS; DOWN-REGULATION; FURANS; GLUTATHIONE; HUMANS; LIGNANS; LUNG NEOPLASMS; NUCLEAR PROTEINS; ONCOGENE PROTEINS; PHYTOTHERAPY; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84888863206     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.08.003     Document Type: Article

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