Mechanism of sporicidal activity for the synergistic combination of peracetic acid and hydrogen peroxide

Applied and Environmental Microbiology

Volumn 82, Issue 4, 2016, Pages 1035-1039

  Leggett, Mark J ^a   Spencer Schwarz, J ^b   Burke, Peter A ^c   McDonnell, Gerald ^c   Denyer, Stephen P ^a   Maillard, Jean Yves ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b STERIS Corporation   (United States)

^c STERIS Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; HYDROGEN PEROXIDE; PERACETIC ACID;

BACTERIAL SPORE; DRUG EFFECTS; DRUG POTENTIATION; MICROBIAL VIABILITY; PHYSIOLOGY;

ANTI-BACTERIAL AGENTS; DRUG SYNERGISM; HYDROGEN PEROXIDE; MICROBIAL VIABILITY; PERACETIC ACID; SPORES, BACTERIAL;

EID: 84957921590     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.03010-15     Document Type: Article

References (31)

1. Setlow P. 2006. Spores of Bacillus subtilis: their resistance to and killing by radiation, heat and chemicals. J Appl Microbiol 101:514-525. http://dx.doi.org/10.1111/j.1365-2672.2005.02736.x.
2. Leggett MJ, McDonnell G, Denyer SP, Setlow P, Maillard J-Y. 2012. Bacterial spore structures and their protective role in biocide resistance. J Appl Microbiol 113:485-498. http://dx.doi.org/10.1111/j.1365-2672.2012 .05336.x.
3. Maillard J-Y. 2011. Innate resistance to sporicides and potential failure to decontaminate. J Hosp Infect 77:204-209. http://dx.doi.org/10.1016/j.jhin.2010.06.028.
4. McDonnell G, Russell AD. 1999. Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev 12:147-179.
5. Melly E, Cowan AE, Setlow P. 2002. Studies on the mechanism of killing of Bacillus subtilis spores by hydrogen peroxide. J Appl Microbiol 93:316-325. http://dx.doi.org/10.1046/j.1365-2672.2002.01687.x.
6. Linley E, Denyer SP, McDonnell G, Simons C, Maillard J-Y. 2012. Use of hydrogen peroxide as a biocide: new consideration of its mechanisms of biocidal action. J Antimicrob Chemother 67:1589-1596. http://dx.doi.org/10.1093/jac/dks129.
7. Leggett MJ, Schwarz JS, Burke PA, McDonnell G, Denyer SP, Maillard J-Y. 2015. Resistance to and killing by the sporicidal microbicide peracetic acid. J Antimicrob Chemother 70:773-779. http://dx.doi.org/10.1093/jac/dku445.
8. Alasri A, Roques C, Michel G, Cabassud C, Aptel P. 1992. Bactericidal properties of peracetic acid and hydrogen peroxide, alone and in combination, and chlorine and formaldehyde against bacterial water strains. Can J Microbiol 38:635-642. http://dx.doi.org/10.1139/m92-104.
9. Alasri A, Valverde M, Roques C, Michel G, Cabassud C, Aptel P. 1993. Sporocidal properties of peracetic acid and hydrogen peroxide, alone and in combination, in comparison with chlorine and formaldehyde for ultrafiltration membrane disinfection. Can J Microbiol 39:52-60. http://dx.doi.org/10.1139/m93-008.
10. Block SS. 2001. Peroxygen compounds, p 185-204. In Block SS (ed), Disinfectio, sterilisation and preservation. Lippincott Williams&Wilkins, Philadelphia, PA.
11. US FDA. 2009. FDA-cleared sterilants and high level disinfectants with general claims for processing reusable medical and dental devices-March 2009. US FDA, Silver Spring, MD.
12. Lambert RJW, Johnston MD, Hanlon GW, Denyer SP. 2003. Theory of antimicrobial combinations: biocide mixtures-synergy or addition? J Appl Microbiol 94:747-759. http://dx.doi.org/10.1046/j.1365-2672.2003 .01908.x.
13. Cortezzo DE, Koziol-Dube K, Setlow B, Setlow P. 2004. Treatment with oxidizing agents damages the inner membrane of spores of Bacillus subtilis and sensitizes spores to subsequent stress. J Appl Microbiol 97:838-852. http://dx.doi.org/10.1111/j.1365-2672.2004.02370.x.
14. Setlow B, Setlow CA, Setlow P. 1997. Killing bacterial spores by organic hydroperoxides. J Ind Microbiol Biotechnol 18:384-388. http://dx.doi.org/10.1038/sj.jim.2900399.
15. Setlow B, Setlow P. 1996. Role of DNA repair in Bacillus subtilis spore resistance. J Bacteriol 178:3486-3495.
16. Young SB, Setlow P. 2003. Mechanisms of killing of Bacillus subtilis spores by hypochlorite and chlorine dioxide. J Appl Microbiol 95:54-67. http://dx.doi.org/10.1046/j.1365-2672.2003.01960.x.
17. Leighton TJ, Doi RH. 1971. The stability of messenger ribonucleic acid during sporulation in Bacillus subtilis. J Biol Chem 246:3189-3195.
18. Nicholson WL, Setlow P. 1990. Sporulation, germination, and outgrowth, p 391-450. In Harwood CR, Cutting SM (ed), Molecular biological methods for Bacillus. John Wiley & Sons Ltd, Chichester, United Kingdom.
19. Geeraerd AH, Valdramidis VP, Van Impe JF. 2005. GInaFiT, a freeware tool to assess non-log-linear microbial survivor curves. Int J Food Microbiol 102:95-105. http://dx.doi.org/10.1016/j.ijfoodmicro.2004.11.038.
20. Setlow B, Setlow P. 1993. Binding of small, acid-soluble spore proteins to DNA plays a significant role in the resistance of Bacillus subtilis spores to hydrogen peroxide. Appl Environ Microbiol 59:3418-3423.
21. Denyer S, Hugo WB, Harding V. 1985. Synergy in preservative combinations. Int J Pharm 25:245-253. http://dx.doi.org/10.1016/0378-5173(85)90166-8.
22. King WL, Gould GW. 1969. Lysis of bacterial spores with hydrogen peroxide. J Appl Bacteriol 32:481-490. http://dx.doi.org/10.1111/j.1365-2672.1969.tb01002.x.
23. Shin S-Y, Calvisi EG, Beaman TC, Pankratz HS, Gerhardt P, Marquis RE. 1994. Microscopic and thermal characterization of hydrogen peroxide killing and lysis of spores and protection by transition metal ions, chelators, and antioxidants. Appl Environ Microbiol 6:3192-3197.
24. Wyatt LR, Waites WM. 1975. Effect of chlorine on spores of Clostridium bifermentans, Bacillus subtilis and Bacillus cereus. J Gen Microbiol 89:337-344. http://dx.doi.org/10.1099/00221287-89-2-337.
25. Driks A. 1999. Bacillus subtilis spore coat. Microbiol Mol Biol Rev 63:1-20.
26. Hullo M-F, Moszer I, Danchin A, Martin-Verstraete I. 2001. CotA of Bacillus subtilis is a copper-dependent laccase. J Bacteriol 183:5426-5430. http://dx.doi.org/10.1128/JB.183.18.5426-5430.2001.
27. Henriques AO, Morran CP. 2007. Structure, assembly, and function of the spore surface layers. Annu Rev Microbiol 61:555-588. http://dx.doi.org/10.1146/annurev.micro.61.080706.093224.
28. Finnegan M, Denyer SP, McDonnell G, Simons C, Maillard J-Y. 2010. Mode of action of hydrogen peroxide and other oxidizing agents: differences. J Antimicrob Chemother 65:2108-2115. http://dx.doi.org/10.1093/jac/dkq308.
29. Young SB, Setlow P. 2004. Mechanisms of killing of Bacillus subtilis spores by Decon and Oxone (TM), two general decontaminants for biological agents. J Appl Microbiol 96:289-301. http://dx.doi.org/10.1046/j.1365-2672.2004.02159.x.
30. Marquis RE, Rutherford GC, Faraci MM, Shin SY. 1995. Sporicidal action of peracetic acid and protective effects of transition metal ions. J Ind Microbiol 15:486-492. http://dx.doi.org/10.1007/BF01570019.
31. Hugo WB, Denyer SP. 1987. The concentration exponent of disinfectants and preservatives (biocides), p 281-291. In Board RG, Allwood MC, Banks JG (ed), Preservatives in the food, pharmaceutical and environmental industries. SAB technical series 22. Blackwell Scientific Publications, Oxford, United Kingdom.