Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry sensitive shifts in target gene networks

Genes and Development

Volumn 29, Issue 23, 2015, Pages 2435-2448

  Latos, Paulina A ^a,b   Sienerth, Arnold R ^a,b   Murray, Alexander ^a,b   Senner, Claire E ^a,b   Muto, Masanaga ^c   Ikawa, Masahito ^c   Oxley, David ^a   Burge, Sarah ^a   Cox, Brian J ^d   Hemberger, Myriam ^a,b  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c OSAKA UNIVERSITY   (Japan)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Control of differentiation; Self renewal; Transcription factor complexes; Transcriptional networks; Trophoblast stem cells

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; EOMES PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR 2; PROTEIN; SPRY4 PROTEIN; TFAP2C PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR ELF5; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTOME; UNCLASSIFIED DRUG; UVOMORULIN; ZIC3 PROTEIN; DNA BINDING PROTEIN; ELF5 PROTEIN, MOUSE; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; BLASTOCYST; CELL CLONING; CELL COMPARTMENTALIZATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EXTRACELLULAR MATRIX; FEMALE; GENE OVEREXPRESSION; GENE TARGETING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STEM CELL EXPANSION; STEM CELL SELF-RENEWAL; STOICHIOMETRY; TROPHOBLAST; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL LINE; CELL SELF-RENEWAL; CHEMISTRY; CYTOLOGY; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETICS; METABOLISM; PROTEIN DOMAIN;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELL SELF RENEWAL; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE REGULATORY NETWORKS; MICE; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; TRANSCRIPTION FACTORS; TROPHOBLASTS;

EID: 84957824087     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.268821.115     Document Type: Article

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