Circulating myeloid-derived suppressor cells in patients with pancreatic cancer

Hepatobiliary and Pancreatic Diseases International

Volumn 15, Issue 1, 2016, Pages 099-105

  Xu, Xiao Dong ^a   Hu, Jun ^b   Wang, Min ^a   Peng, Feng ^a   Tian, Rui ^a   Guo, Xing Jun ^a   Xie, Yu ^a   Qin, Ren Yi ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

arginase; granulocyte macrophage colony stimulating factor; Key Words pancreatic cancer; myeloid derived suppressor cells

Indexed keywords

ARGINASE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 6; VASCULOTROPIN; CD11B ANTIGEN; CD14 ANTIGEN; HLA DR ANTIGEN; ITGAM PROTEIN, HUMAN; TUMOR MARKER;

ADULT; AGED; ARTICLE; BILE DUCT CANCER; BONE MARROW CELL; CANCER PATIENT; CANCER STAGING; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; MALE; MYELOID DERIVED SUPPRESSOR CELL; PANCREAS CANCER; PERIPHERAL BLOOD MONONUCLEAR CELL; SUPPRESSOR CELL; TUMOR CELL; BILE DUCT CARCINOMA; BILE DUCT TUMOR; BLOOD; CASE CONTROL STUDY; COCULTURE; IMMUNOLOGY; METABOLISM; MIDDLE AGED; MONONUCLEAR CELL; PANCREAS TUMOR; PATHOLOGY; TUMOR CELL LINE; TUMOR ESCAPE; TUMOR VOLUME;

AGED; ANTIGENS, CD11B; ANTIGENS, CD14; ARGINASE; BILE DUCT NEOPLASMS; BIOMARKERS, TUMOR; CASE-CONTROL STUDIES; CELL LINE, TUMOR; CHOLANGIOCARCINOMA; COCULTURE TECHNIQUES; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HLA-DR ANTIGENS; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; MYELOID CELLS; PANCREATIC NEOPLASMS; TUMOR BURDEN; TUMOR ESCAPE;

EID: 84957810946     PISSN: 14993872     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1499-3872(15)60413-1     Document Type: Article

References (37)

1. GL Beatty, EG Chiorean, MP Fishman, B Saboury, UR Teitelbaum, W Sun et al. CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans Science 331 2011 1612 1616
2. B Almand, JI Clark, E Nikitina, J van Beynen, NR English, SC Knight et al. Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer J Immunol 166 2001 678 689
3. CE Clark, SR Hingorani, R Mick, C Combs, DA Tuveson, RH Vonderheide Dynamics of the immune reaction to pancreatic cancer from inception to invasion Cancer Res 67 2007 9518 9527
4. V Bronte, DB Chappell, E Apolloni, A Cabrelle, M Wang, P Hwu et al. Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation J Immunol 162 1999 5728 5737
5. JI Youn, S Nagaraj, M Collazo, DI Gabrilovich Subsets of myeloid-derived suppressor cells in tumor-bearing mice J Immunol 181 2008 5791 5802
6. J Schmielau, OJ Finn Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of t-cell function in advanced cancer patients Cancer Res 61 2001 4756 4760
7. CM Diaz-Montero, ML Salem, MI Nishimura, E Garrett-Mayer, DJ Cole, AJ Montero Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy Cancer Immunol Immunother 58 2009 49 59
8. BL Mundy-Bosse, GS Young, T Bauer, E Binkley, M Bloomston, MA Bill et al. Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4(+) T cells from patients with GI malignancy Cancer Immunol Immunother 60 2011 1269 1279
9. RF Gabitass, NE Annels, DD Stocken, HA Pandha, GW Middleton Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13 Cancer Immunol Immunother 60 2011 1419 1430
10. MR Porembka, JB Mitchem, BA Belt, CS Hsieh, HM Lee, J Herndon et al. Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth Cancer Immunol Immunother 61 2012 1373 1385
11. F Rey-Giraud, M Hafner, CH Ries In vitro generation of monocyte-derived macrophages under serum-free conditions improves their tumor promoting functions PLoS One 7 2012 e42656
12. J Choi, B Suh, YO Ahn, TM Kim, JO Lee, SH Lee et al. CD15+/CD16low human granulocytes from terminal cancer patients: granulocytic myeloid-derived suppressor cells that have suppressive function Tumour Biol 33 2012 121 129
13. B Hoechst, LA Ormandy, M Ballmaier, F Lehner, C Krüger, MP Manns et al. A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells Gastroenterology 135 2008 234 243
14. B Hoechst, T Voigtlaender, L Ormandy, J Gamrekelashvili, F Zhao, H Wedemeyer et al. Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor Hepatology 50 2009 799 807
15. JC Rodrigues, GC Gonzalez, L Zhang, G Ibrahim, JJ Kelly, MP Gustafson et al. Normal human monocytes exposed to glioma cells acquire myeloid-derived suppressor cell-like properties Neuro Oncol 12 2010 351 365
16. JK Morales, M Kmieciak, KL Knutson, HD Bear, MH Manjili GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells Breast Cancer Res Treat 123 2010 39 49
17. AC Ochoa, AH Zea, C Hernandez, PC Rodriguez Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma Clin Cancer Res 13 2007 721s 726s
18. S Kusmartsev, Y Nefedova, D Yoder, DI Gabrilovich Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species J Immunol 172 2004 989 999
19. W Jia, C Jackson-Cook, MR Graf Tumor-infiltrating, myeloid-derived suppressor cells inhibit T cell activity by nitric oxide production in an intracranial rat glioma + vaccination model J Neuroimmunol 223 2010 20 30
20. G Bellone, A Turletti, E Artusio, K Mareschi, A Carbone, D Tibaudi et al. Tumor-associated transforming growth factor-beta and interleukin-10 contribute to a systemic Th2 immune phenotype in pancreatic carcinoma patients Am J Pathol 155 1999 537 547
21. MK Srivastava, P Sinha, VK Clements, P Rodriguez, S Ostrand-Rosenberg Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine Cancer Res 70 2010 68 77
22. B Zhang, Z Wang, L Wu, M Zhang, W Li, J Ding et al. Circulating and tumor-infiltrating myeloid-derived suppressor cells in patients with colorectal carcinoma PLoS One 8 2013 e57114
23. MG Lechner, C Megiel, SM Russell, B Bingham, N Arger, T Woo et al. Functional characterization of human Cd33+ and Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines J Transl Med 9 2011 90
24. LJ Bayne, GL Beatty, N Jhala, CE Clark, AD Rhim, BZ Stanger et al. Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer Cancer Cell 21 2012 822 835
25. Y Pylayeva-Gupta, KE Lee, CH Hajdu, G Miller, D Bar-Sagi Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia Cancer Cell 21 2012 836 847
26. Y Zhang, W Yan, MA Collins, F Bednar, S Rakshit, BR Zetter et al. Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance Cancer Res 73 2013 6359 6374
27. TA Mace, Z Ameen, A Collins, S Wojcik, M Mair, GS Young et al. Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner Cancer Res 73 2013 3007 3018
28. I Marigo, E Bosio, S Solito, C Mesa, A Fernandez, L Dolcetti et al. Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor Immunity 32 2010 790 802
29. Y Liu, L Lai, Q Chen, Y Song, S Xu, F Ma et al. MicroRNA-494 is required for the accumulation and functions of tumor-expanded myeloid-derived suppressor cells via targeting of PTEN J Immunol 188 2012 5500 5510
30. P Shen, A Wang, M He, Q Wang, S Zheng Increased circulating Lin(-/low) CD33(+) HLA-DR(-) myeloid-derived suppressor cells in hepatocellular carcinoma patients Hepatol Res 44 2014 639 650
31. B Mroczko, M Szmitkowski, U Wereszczyńska-Siemiatkowska, G Jurkowska Hematopoietic cytokines in the sera of patients with pancreatic cancer Clin Chem Lab Med 43 2005 146 150
32. G Vasiliades, N Kopanakis, M Vasiloglou, G Zografos, H Margaris, K Masselou et al. Role of the hematopoietic cytokines SCF, IL-3, GM-CSF and M-CSF in the diagnosis of pancreatic and ampullary cancer Int J Biol Markers 27 2012 e186 e194
33. T Starzyńska, K Dabkowski, W Błogowski, E Zuba-Surma, M Budkowska, D Sałata et al. An intensified systemic trafficking of bone marrow-derived stem/progenitor cells in patients with pancreatic cancer J Cell Mol Med 17 2013 792 799
34. W Błogowski, A Deskur, M Budkowska, D Sałata, A Madej-Michniewicz, K Dabkowski et al. Selected cytokines in patients with pancreatic cancer: a preliminary report PLoS One 9 2014 e97613
35. AL Pauleau, R Rutschman, R Lang, A Pernis, SS Watowich, PJ Murray Enhancer-mediated control of macrophage-specific arginase I expression J Immunol 172 2004 7565 7573
36. I Poschke, D Mougiakakos, J Hansson, GV Masucci, R Kiessling Immature immunosuppressive CD14+HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign Cancer Res 70 2010 4335 4345
37. B Raychaudhuri, P Rayman, J Ireland, J Ko, B Rini, EC Borden et al. Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma Neuro Oncol 13 2011 591 599