-
1
-
-
67649094526
-
From lab to bedside: Emerging clinical applications of thymosin alpha 1
-
Goldstein AL, Goldstein AL. From lab to bedside: emerging clinical applications of thymosin alpha 1. Expert Opin Biol Ther 2009;9:593-608
-
(2009)
Expert Opin Biol Ther
, vol.9
, pp. 593-608
-
-
Goldstein, A.L.1
Goldstein, A.L.2
-
2
-
-
35348982764
-
Thymosin alpha1: A historical overview
-
Garaci E. Thymosin alpha1: a historical overview. Ann N Y Acad Sci 2007;1112:14-20
-
(2007)
Ann N Y Acad Sci
, vol.1112
, pp. 14-20
-
-
Garaci, E.1
-
3
-
-
0026545993
-
Serum levels of immunoreactive thymosin alpha 1 and thymosin beta 4 in large cohorts of healthy adults
-
Weller FE, Shah U, Cummings GD, et al. Serum levels of immunoreactive thymosin alpha 1 and thymosin beta 4 in large cohorts of healthy adults. Thymus 1992;19:45-52
-
(1992)
Thymus
, vol.19
, pp. 45-52
-
-
Weller, F.E.1
Shah, U.2
Cummings, G.D.3
-
4
-
-
0036557949
-
Thymosin alpha1. SciClone Pharmaceuticals
-
Billich A. Thymosin alpha1. SciClone Pharmaceuticals. Curr Opin Investig Drugs 2002;3:698-707
-
(2002)
Curr Opin Investig Drugs
, vol.3
, pp. 698-707
-
-
Billich, A.1
-
5
-
-
84983404647
-
Thymosin Apha 1--A Peptide Immune Modulator with a Broad Range of Clinical Applications
-
Tuthill CW, King RS. Thymosin Apha 1--A Peptide Immune Modulator with a Broad Range of Clinical Applications. Clin Exp Pharmacol 2013;3:133
-
(2013)
Clin Exp Pharmacol
, vol.3
, pp. 133
-
-
Tuthill, C.W.1
King, R.S.2
-
6
-
-
2542451903
-
Thymosin alpha 1 activates dendritic cells for antifungal Th1 resistance through toll-like receptor signaling
-
Romani L, Bistoni F, Gaziano R, et al. Thymosin alpha 1 activates dendritic cells for antifungal Th1 resistance through toll-like receptor signaling. Blood 2004;103:4232-9
-
(2004)
Blood
, vol.103
, pp. 4232-4239
-
-
Romani, L.1
Bistoni, F.2
Gaziano, R.3
-
7
-
-
22144466919
-
Activation of IKK by thymosin alpha1 requires the TRAF6 signalling pathway
-
Zhang P, Chan J, Dragoi AM, et al. Activation of IKK by thymosin alpha1 requires the TRAF6 signalling pathway. EMBO Rep 2005;6:531-7
-
(2005)
EMBO Rep
, vol.6
, pp. 531-537
-
-
Zhang, P.1
Chan, J.2
Dragoi, A.M.3
-
8
-
-
33749335671
-
Thymosin alpha1 activates dendritic cell tryptophan catabolism and establishes a regulatory environment for balance of inflammation and tolerance
-
Romani L, Bistoni F, Perruccio K, et al. Thymosin alpha1 activates dendritic cell tryptophan catabolism and establishes a regulatory environment for balance of inflammation and tolerance. Blood 2006;108:2265-74
-
(2006)
Blood
, vol.108
, pp. 2265-2274
-
-
Romani, L.1
Bistoni, F.2
Perruccio, K.3
-
10
-
-
84867368084
-
Jack of all trades: Thymosin alpha1 and its pleiotropy
-
Romani L, Moretti S, Fallarino F, et al. Jack of all trades: thymosin alpha1 and its pleiotropy. Ann N Y Acad Sci 2012;1269:1-6
-
(2012)
Ann N Y Acad Sci
, vol.1269
, pp. 1-6
-
-
Romani, L.1
Moretti, S.2
Fallarino, F.3
-
11
-
-
35349010606
-
Thymosin alpha1 activates the TLR9/MyD88/IRF7-dependent murine cytomegalovirus sensing for induction of anti-viral responses in vivo
-
Bozza S, Gaziano R, Bonifazi P, et al. Thymosin alpha1 activates the TLR9/MyD88/IRF7-dependent murine cytomegalovirus sensing for induction of anti-viral responses in vivo. Int Immunol 2007;19:1261-70
-
(2007)
Int Immunol
, vol.19
, pp. 1261-1270
-
-
Bozza, S.1
Gaziano, R.2
Bonifazi, P.3
-
12
-
-
35349015651
-
Thymosin alpha1: An endogenous regulator of inflammation immunity and tolerance
-
Romani L, Bistoni F, Montagnoli C, et al. Thymosin alpha1: an endogenous regulator of inflammation immunity and tolerance. Ann N Y Acad Sci 2007;1112:326-38
-
(2007)
Ann N Y Acad Sci
, vol.1112
, pp. 326-338
-
-
Romani, L.1
Bistoni, F.2
Montagnoli, C.3
-
13
-
-
2342464085
-
The two NFkappaB activation pathways and their role in innate and adaptive immunity
-
Bonizzi G, Karin M. The two NFkappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol 2004;25:280-8
-
(2004)
Trends Immunol
, vol.25
, pp. 280-288
-
-
Bonizzi, G.1
Karin, M.2
-
15
-
-
77649086402
-
Immune adaptations that maintain homeostasis with the intestinal microbiota
-
Hooper LV, Macpherson AJ. Immune adaptations that maintain homeostasis with the intestinal microbiota. Nat Rev Immunol 2010;10:159-69
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 159-169
-
-
Hooper, L.V.1
Macpherson, A.J.2
-
16
-
-
84902657771
-
Diet metabolites and “western-lifestyle” inflammatory diseases
-
Thorburn AN, Macia L, Mackay CR. Diet metabolites and “western-lifestyle” inflammatory diseases. Immunity 2014;40:833-42
-
(2014)
Immunity
, vol.40
, pp. 833-842
-
-
Thorburn, A.N.1
Macia, L.2
Mackay, C.R.3
-
17
-
-
84888872209
-
Controlling the frontier: Regulatory T-cells and intestinal homeostasis
-
Bollrath J, Powrie FM. Controlling the frontier: regulatory T-cells and intestinal homeostasis. Semin Immunol 2013;25:352-7
-
(2013)
Semin Immunol
, vol.25
, pp. 352-357
-
-
Bollrath, J.1
Powrie, F.M.2
-
18
-
-
84958548312
-
Tr1 cells and the counterregulation of immunity: Natural mechanisms and therapeutic applications
-
Roncarolo MG, Gregori S, Bacchetta R, et al. Tr1 cells and the counterregulation of immunity: natural mechanisms and therapeutic applications. Curr Top Microbiol Immunol 2014;380:39-68
-
(2014)
Curr Top Microbiol Immunol
, vol.380
, pp. 39-68
-
-
Roncarolo, M.G.1
Gregori, S.2
Bacchetta, R.3
-
19
-
-
84897941063
-
Thornton AM. TTregs, pTregs, and iTregs: Similarities and differences
-
Shevach EM, Thornton AM. tTregs, pTregs, and iTregs: similarities and differences. Immunol Rev 2014;259:88-102
-
(2014)
Immunol Rev
, vol.259
, pp. 88-102
-
-
Shevach, E.M.1
-
20
-
-
34748835898
-
IDO and regulatory T cells: A role for reverse signalling and non-canonical NF-kappaB activation
-
Puccetti P, Grohmann U. IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activation. Nat Rev Immunol 2007;7:817-23
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 817-823
-
-
Puccetti, P.1
Grohmann, U.2
-
21
-
-
84865296997
-
Amino acid catabolism: A pivotal regulator of innate and adaptive immunity
-
McGaha TL, Huang L, Lemos H, et al. Amino acid catabolism: a pivotal regulator of innate and adaptive immunity. Immunol Rev 2012;249:135-57
-
(2012)
Immunol Rev
, vol.249
, pp. 135-157
-
-
McGaha, T.L.1
Huang, L.2
Lemos, H.3
-
22
-
-
84875261622
-
Indoleamine 23 dioxygenase and metabolic control of immune responses
-
Munn DH, Mellor AL. Indoleamine 23 dioxygenase and metabolic control of immune responses. Trends Immunol 2013;34:137-43
-
(2013)
Trends Immunol
, vol.34
, pp. 137-143
-
-
Munn, D.H.1
Mellor, A.L.2
-
23
-
-
0346599403
-
An autoimmune disease APECED caused by mutations in a novel gene featuring two PHD-type zinc-finger domains
-
Finnish-German AC. An autoimmune disease APECED caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. Nat Genet 1997;17:399-403
-
(1997)
Nat Genet
, vol.17
, pp. 399-403
-
-
Finnish-German, A.C.1
-
26
-
-
56749161528
-
Transcriptional regulation by AIRE: Molecular mechanisms of central tolerance
-
Peterson P, Org T, Rebane A. Transcriptional regulation by AIRE: molecular mechanisms of central tolerance. Nat Rev Immunol 2008;8:948-57
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 948-957
-
-
Peterson, P.1
Org, T.2
Rebane, A.3
-
27
-
-
22344449972
-
Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels
-
Derbinski J, Gabler J, Brors B, et al. Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels. J Exp Med 2005;202:33-45
-
(2005)
J Exp Med
, vol.202
, pp. 33-45
-
-
Derbinski, J.1
Gabler, J.2
Brors, B.3
-
29
-
-
79954463242
-
Control of central and peripheral tolerance by Aire
-
Metzger TC, Anderson MS. Control of central and peripheral tolerance by Aire. Immunol Rev 2011;241:89-103
-
(2011)
Immunol Rev
, vol.241
, pp. 89-103
-
-
Metzger, T.C.1
Erson, M.S.2
-
30
-
-
0037112047
-
Projection of an immunological self shadow within the thymus by the aire protein
-
Anderson MS, Venanzi ES, Klein L, et al. Projection of an immunological self shadow within the thymus by the aire protein. Science 2002;298:1395-401
-
(2002)
Science
, vol.298
, pp. 1395-1401
-
-
Anderson, M.S.1
Venanzi, E.S.2
Klein, L.3
-
31
-
-
77749279470
-
Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells
-
Poliani PL, Kisand K, Marrella V, et al. Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells. Am J Pathol 2010;176:1104-12
-
(2010)
Am J Pathol
, vol.176
, pp. 1104-1112
-
-
Poliani, P.L.1
Kisand, K.2
Marrella, V.3
-
32
-
-
49449093723
-
Deletional tolerance mediated by extrathymic Aire-expressing cells
-
Gardner JM, Devoss JJ, Friedman RS, et al. Deletional tolerance mediated by extrathymic Aire-expressing cells. Science 2008;321:843-7
-
(2008)
Science
, vol.321
, pp. 843-847
-
-
Gardner, J.M.1
Devoss, J.J.2
Friedman, R.S.3
-
33
-
-
0027788091
-
Immunoreactive thymosin alpha 1 in human thymus and thymoma
-
Naruse H, Hashimoto T, Yamakawa Y, et al. Immunoreactive thymosin alpha 1 in human thymus and thymoma. J Thorac Cardiovasc Surg 1993;106:1065-71
-
(1993)
J Thorac Cardiovasc Surg
, vol.106
, pp. 1065-1071
-
-
Naruse, H.1
Hashimoto, T.2
Yamakawa, Y.3
-
34
-
-
0019432473
-
Immunocytochemical localization of thymosin-alpha 1 in thymic epithelial cells of normal and myasthenia gravis patients and in thymic cultures
-
Dalakas MC, Engel WK, McClure JE, et al. Immunocytochemical localization of thymosin-alpha 1 in thymic epithelial cells of normal and myasthenia gravis patients and in thymic cultures. J Neurol Sci 1981;50:239-47
-
(1981)
J Neurol Sci
, vol.50
, pp. 239-247
-
-
Dalakas, M.C.1
Engel, W.K.2
McClure, J.E.3
-
35
-
-
24144480562
-
Hassall’s corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus
-
Watanabe N, Wang YH, Lee HK, et al. Hassall’s corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus. Nature 2005;436:1181-5
-
(2005)
Nature
, vol.436
, pp. 1181-1185
-
-
Watanabe, N.1
Wang, Y.H.2
Lee, H.K.3
-
36
-
-
2442582732
-
Human thymic stromal lymphopoietin promotes dendritic cellmediated CD4+ T cell homeostatic expansion
-
Watanabe N, Hanabuchi S, Soumelis V, et al. Human thymic stromal lymphopoietin promotes dendritic cellmediated CD4+ T cell homeostatic expansion. Nat Immunol 2004;5:426-34
-
(2004)
Nat Immunol
, vol.5
, pp. 426-434
-
-
Watanabe, N.1
Hanabuchi, S.2
Soumelis, V.3
-
37
-
-
84861926185
-
The multiple facets of thymic stromal lymphopoietin (TSLP) during allergic inflammation and beyond
-
Roan F, Bell BD, Stoklasek TA, et al. The multiple facets of thymic stromal lymphopoietin (TSLP) during allergic inflammation and beyond. J Leukoc Biol 2012;91:877-86
-
(2012)
J Leukoc Biol
, vol.91
, pp. 877-886
-
-
Roan, F.1
Bell, B.D.2
Stoklasek, T.A.3
-
38
-
-
0038306841
-
Prothymosin alpha is processed to thymosin alpha 1 and thymosin alpha 11 by a lysosomal asparaginyl endopeptidase
-
Sarandeses CS, Covelo G, Diaz-Jullien C, et al. Prothymosin alpha is processed to thymosin alpha 1 and thymosin alpha 11 by a lysosomal asparaginyl endopeptidase. J Biol Chem 2003;278:13286-93
-
(2003)
J Biol Chem
, vol.278
, pp. 13286-13293
-
-
Sarandeses, C.S.1
Covelo, G.2
Diaz-Jullien, C.3
-
39
-
-
78650328690
-
Increased IL-17A secretion in response to Candida albicans in autoimmune polyendocrine syndrome type 1 and its animal model
-
Ahlgren KM, Moretti S, Lundgren BA, et al. Increased IL-17A secretion in response to Candida albicans in autoimmune polyendocrine syndrome type 1 and its animal model. Eur J Immunol 2011;41:235-45
-
(2011)
Eur J Immunol
, vol.41
, pp. 235-245
-
-
Ahlgren, K.M.1
Moretti, S.2
Lundgren, B.A.3
-
40
-
-
84882664672
-
Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22
-
Zelante T, Iannitti RG, Cunha C, et al. Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22. Immunity 2013;39:372-85
-
(2013)
Immunity
, vol.39
, pp. 372-385
-
-
Zelante, T.1
Iannitti, R.G.2
Cunha, C.3
-
41
-
-
5144231380
-
Autoimmune regulator induced changes in the gene expression profile of human monocytedendritic cell-lineage
-
Sillanpaa N, Magureanu CG, Murumagi A, et al. Autoimmune regulator induced changes in the gene expression profile of human monocytedendritic cell-lineage. Mol Immunol 2004;41:1185-98
-
(2004)
Mol Immunol
, vol.41
, pp. 1185-1198
-
-
Sillanpaa, N.1
Magureanu, C.G.2
Murumagi, A.3
-
42
-
-
77958477060
-
Non-hematopoietic cells contribute to protective tolerance to Aspergillus fumigatus via a TRIF pathway converging on IDO
-
de Luca A, Bozza S, Zelante T, et al. Non-hematopoietic cells contribute to protective tolerance to Aspergillus fumigatus via a TRIF pathway converging on IDO. Cell Mol Immunol 2010;7:459-70
-
(2010)
Cell Mol Immunol
, vol.7
, pp. 459-470
-
-
De Luca, A.1
Bozza, S.2
Zelante, T.3
-
43
-
-
37349076668
-
Functional yet balanced reactivity to Candida albicans requires TRIF, MyD88, and IDO-dependent inhibition of Rorc
-
De Luca A, Montagnoli C, Zelante T, et al. Functional yet balanced reactivity to Candida albicans requires TRIF, MyD88, and IDO-dependent inhibition of Rorc. J Immunol 2007;179:5999-6008
-
(2007)
J Immunol
, vol.179
, pp. 5999-6008
-
-
De Luca, A.1
Montagnoli, C.2
Zelante, T.3
|