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Volumn 11, Issue 2, 2016, Pages 201-208

Immune activation in HIV infection: What can the natural hosts of simian immunodeficiency virus teach us?

Author keywords

inflammation; microbial translocation; natural hosts; reservoirs; simian immunodeficiency virus

Indexed keywords

INTERFERON;

EID: 84957652377     PISSN: 1746630X     EISSN: 17466318     Source Type: Journal    
DOI: 10.1097/COH.0000000000000238     Document Type: Review
Times cited : (18)

References (79)
  • 1
    • 59649097925 scopus 로고    scopus 로고
    • African non human primates infected by SIV: Why don't they get sick? Lessons from studies on the early phase of nonpathogenic SIV infection
    • Liovat AS, Jacquelin B, Ploquin MJ, et al. African non human primates infected by SIV: why don't they get sick? Lessons from studies on the early phase of nonpathogenic SIV infection. Curr HIV Res 2009; 7: 39-50.
    • (2009) Curr HIV Res , vol.7 , pp. 39-50
    • Liovat, A.S.1    Jacquelin, B.2    Ploquin, M.J.3
  • 2
    • 0035121414 scopus 로고    scopus 로고
    • Simian immunodeficiency virus replicates to high levels in naturally infected African green monkeys without inducing immunologic or neurologic disease
    • Broussard SR, Staprans SI, White R, et al. Simian immunodeficiency virus replicates to high levels in naturally infected African green monkeys without inducing immunologic or neurologic disease. J Virol 2001; 75: 2262-2275.
    • (2001) J Virol , vol.75 , pp. 2262-2275
    • Broussard, S.R.1    Staprans, S.I.2    White, R.3
  • 3
    • 0034467866 scopus 로고    scopus 로고
    • Wide range of viral load in healthy African green monkeys naturally infected with simian immunodeficiency virus
    • Goldstein S, Ourmanov I, Brown CR, et al. Wide range of viral load in healthy African green monkeys naturally infected with simian immunodeficiency virus. J Virol 2000; 74: 11744-11753.
    • (2000) J Virol , vol.74 , pp. 11744-11753
    • Goldstein, S.1    Ourmanov, I.2    Brown, C.R.3
  • 4
    • 1842586066 scopus 로고    scopus 로고
    • Viral load in tissues during the early and chronic phase of non-pathogenic SIVagm infection
    • Gueye A, Diop OM, Ploquin MJ, et al. Viral load in tissues during the early and chronic phase of non-pathogenic SIVagm infection. J Med Primatol 2004; 33: 83-97.
    • (2004) J Med Primatol , vol.33 , pp. 83-97
    • Gueye, A.1    Diop, O.M.2    Ploquin, M.J.3
  • 5
    • 41149083421 scopus 로고    scopus 로고
    • Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: Implications for AIDS pathogenesis
    • Gordon SN, Dunham RM, Engram JC, et al. Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis. J Virol 2008; 82: 3725-3735.
    • (2008) J Virol , vol.82 , pp. 3725-3735
    • Gordon, S.N.1    Dunham, R.M.2    Engram, J.C.3
  • 6
    • 45749156336 scopus 로고    scopus 로고
    • Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys
    • Klatt NR, Villinger F, Bostik P, et al. Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys. J Clin Invest 2008; 118: 2039-2049.
    • (2008) J Clin Invest , vol.118 , pp. 2039-2049
    • Klatt, N.R.1    Villinger, F.2    Bostik, P.3
  • 7
    • 41149146472 scopus 로고    scopus 로고
    • Simian immunodeficiency virus SIVagm dynamics in African green monkeys
    • Pandrea I, Ribeiro RM, Gautam R, et al. Simian immunodeficiency virus SIVagm dynamics in African green monkeys. J Virol 2008; 82: 3713-3724.
    • (2008) J Virol , vol.82 , pp. 3713-3724
    • Pandrea, I.1    Ribeiro, R.M.2    Gautam, R.3
  • 8
    • 36048989052 scopus 로고    scopus 로고
    • Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence
    • Pandrea IV, Gautam R, Ribeiro RM, et al. Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence. J Immunol 2007; 179: 3035-3046.
    • (2007) J Immunol , vol.179 , pp. 3035-3046
    • Pandrea, I.V.1    Gautam, R.2    Ribeiro, R.M.3
  • 9
    • 77958083540 scopus 로고    scopus 로고
    • Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections
    • Estes JD, Harris LD, Klatt NR, et al. Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections. PLoS Pathog 2010; 6: e1001052.
    • (2010) PLoS Pathog , vol.6 , pp. e1001052
    • Estes, J.D.1    Harris, L.D.2    Klatt, N.R.3
  • 10
    • 84879295275 scopus 로고    scopus 로고
    • HIV-associated chronic immune activation
    • Paiardini M, Muller-Trutwin M. HIV-associated chronic immune activation. Immunol Rev 2013; 254: 78-101.
    • (2013) Immunol Rev , vol.254 , pp. 78-101
    • Paiardini, M.1    Muller-Trutwin, M.2
  • 11
    • 0033962875 scopus 로고    scopus 로고
    • Normal T-cell turnover in sooty mangabeys harboring active simian immunodeficiency virus infection
    • Chakrabarti LA, Lewin SR, Zhang L, et al. Normal T-cell turnover in sooty mangabeys harboring active simian immunodeficiency virus infection. J Virol 2000; 74: 1209-1223.
    • (2000) J Virol , vol.74 , pp. 1209-1223
    • Chakrabarti, L.A.1    Lewin, S.R.2    Zhang, L.3
  • 12
    • 20144387661 scopus 로고    scopus 로고
    • Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS
    • Kornfeld C, Ploquin MJ, Pandrea I, et al. Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS. J Clin Invest 2005; 115: 1082-1091.
    • (2005) J Clin Invest , vol.115 , pp. 1082-1091
    • Kornfeld, C.1    Ploquin, M.J.2    Pandrea, I.3
  • 13
    • 0033861039 scopus 로고    scopus 로고
    • High levels of viral replication during primary simian immunodeficiency virus SIVagm infection are rapidly and strongly controlled in African green monkeys
    • Diop OM, Gueye A, Dias-Tavares M, et al. High levels of viral replication during primary simian immunodeficiency virus SIVagm infection are rapidly and strongly controlled in African green monkeys. J Virol 2000; 74: 7538-7547.
    • (2000) J Virol , vol.74 , pp. 7538-7547
    • Diop, O.M.1    Gueye, A.2    Dias-Tavares, M.3
  • 14
    • 84865171842 scopus 로고    scopus 로고
    • Coagulation biomarkers predict disease progression in SIV-infected nonhuman primates
    • Pandrea I, Cornell E, Wilson C, et al. Coagulation biomarkers predict disease progression in SIV-infected nonhuman primates. Blood 2012; 120: 1357-1366.
    • (2012) Blood , vol.120 , pp. 1357-1366
    • Pandrea, I.1    Cornell, E.2    Wilson, C.3
  • 15
    • 84879318140 scopus 로고    scopus 로고
    • Immune activation and HIV persistence: Implications for curative approaches to HIV infection
    • Klatt NR, Chomont N, Douek DC, Deeks SG. Immune activation and HIV persistence: implications for curative approaches to HIV infection. Immunol Rev 2013; 254: 326-342.
    • (2013) Immunol Rev , vol.254 , pp. 326-342
    • Klatt, N.R.1    Chomont, N.2    Douek, D.C.3    Deeks, S.G.4
  • 16
    • 33747090617 scopus 로고    scopus 로고
    • Distinct expression profiles of TGF-beta1 signaling mediators in pathogenic SIVmac and nonpathogenic SIVagm infections
    • Ploquin MJ, Desoutter JF, Santos PR, et al. Distinct expression profiles of TGF-beta1 signaling mediators in pathogenic SIVmac and nonpathogenic SIVagm infections. Retrovirology 2006; 3: 37.
    • (2006) Retrovirology , vol.3 , pp. 37
    • Ploquin, M.J.1    Desoutter, J.F.2    Santos, P.R.3
  • 17
    • 45449104669 scopus 로고    scopus 로고
    • Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques
    • Cecchinato V, Trindade CJ, Laurence A, et al. Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques. Mucosal Immunol 2008; 1: 279-288.
    • (2008) Mucosal Immunol , vol.1 , pp. 279-288
    • Cecchinato, V.1    Trindade, C.J.2    Laurence, A.3
  • 18
    • 61449115882 scopus 로고    scopus 로고
    • Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection
    • Favre D, Lederer S, Kanwar B, et al. Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection. PLoS Pathog 2009; 5: e1000295.
    • (2009) PLoS Pathog , vol.5 , pp. e1000295
    • Favre, D.1    Lederer, S.2    Kanwar, B.3
  • 19
    • 72849132344 scopus 로고    scopus 로고
    • Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys
    • Bosinger SE, Li Q, Gordon SN, et al. Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys. J Clin Invest 2009; 119: 3556-3572.
    • (2009) J Clin Invest , vol.119 , pp. 3556-3572
    • Bosinger, S.E.1    Li, Q.2    Gordon, S.N.3
  • 20
    • 75449089285 scopus 로고    scopus 로고
    • Nonpathogenesis of simian immunodeficiency virus infection is associated with reduced inflammation and recruitment of plasmacytoid dendritic cells to lymph nodes, not to lack of an interferon type i response, during the acute phase
    • Campillo-Gimenez L, Laforge M, Fay M, et al. Nonpathogenesis of simian immunodeficiency virus infection is associated with reduced inflammation and recruitment of plasmacytoid dendritic cells to lymph nodes, not to lack of an interferon type I response, during the acute phase. J Virol 2010; 84: 1838-1846.
    • (2010) J Virol , vol.84 , pp. 1838-1846
    • Campillo-Gimenez, L.1    Laforge, M.2    Fay, M.3
  • 21
    • 43949088825 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cell dynamics and alpha interferon production during simian immunodeficiency virus infection with a nonpathogenic outcome
    • Diop OM, Ploquin MJ, Mortara L, et al. Plasmacytoid dendritic cell dynamics and alpha interferon production during simian immunodeficiency virus infection with a nonpathogenic outcome. J Virol 2008; 82: 5145-5152.
    • (2008) J Virol , vol.82 , pp. 5145-5152
    • Diop, O.M.1    Ploquin, M.J.2    Mortara, L.3
  • 22
    • 77954498359 scopus 로고    scopus 로고
    • Downregulation of robust acute type i interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques
    • Harris LD, Tabb B, Sodora DL, et al. Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques. J Virol 2010; 84: 7886-7891.
    • (2010) J Virol , vol.84 , pp. 7886-7891
    • Harris, L.D.1    Tabb, B.2    Sodora, D.L.3
  • 23
    • 72849136282 scopus 로고    scopus 로고
    • Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type i IFN response
    • Jacquelin B, Mayau V, Targat B, et al. Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response. J Clin Invest 2009; 119: 3544-3555.
    • (2009) J Clin Invest , vol.119 , pp. 3544-3555
    • Jacquelin, B.1    Mayau, V.2    Targat, B.3
  • 24
    • 84905367955 scopus 로고    scopus 로고
    • Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferonalpha during primary SIVagm infection
    • Jacquelin B, Petitjean G, Kunkel D, et al. Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferonalpha during primary SIVagm infection. PLoS Pathog 2014; 10: e1004241. The work confirms that the control of immune activation in natural hosts is not a consequence of lower levels of IFN-a production.
    • (2014) PLoS Pathog , vol.10 , pp. e1004241
    • Jacquelin, B.1    Petitjean, G.2    Kunkel, D.3
  • 25
    • 84883365277 scopus 로고    scopus 로고
    • Intact type i interferon production and IRF7 function in sooty mangabeys
    • Bosinger SE, Johnson ZP, Folkner KA, et al. Intact type I interferon production and IRF7 function in sooty mangabeys. PLoS Pathog 2013; 9: e1003597.
    • (2013) PLoS Pathog , vol.9 , pp. e1003597
    • Bosinger, S.E.1    Johnson, Z.P.2    Folkner, K.A.3
  • 26
    • 84930891753 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cell infection and sensing capacity during pathogenic and nonpathogenic simian immunodeficiency virus infection
    • Jochems SP, Jacquelin B, Chauveau L, et al. Plasmacytoid dendritic cell infection and sensing capacity during pathogenic and nonpathogenic simian immunodeficiency virus infection. J Virol 2015; 89: 6918-6927.
    • (2015) J Virol , vol.89 , pp. 6918-6927
    • Jochems, S.P.1    Jacquelin, B.2    Chauveau, L.3
  • 27
    • 77952739975 scopus 로고    scopus 로고
    • Nonpathogenic simian immunodeficiency virus infection of sooty mangabeys is not associated with high levels of autologous neutralizing antibodies
    • Li B, Stefano-Cole K, Kuhrt DM, et al. Nonpathogenic simian immunodeficiency virus infection of sooty mangabeys is not associated with high levels of autologous neutralizing antibodies. J Virol 2010; 84: 6248-6253.
    • (2010) J Virol , vol.84 , pp. 6248-6253
    • Li, B.1    Stefano-Cole, K.2    Kuhrt, D.M.3
  • 28
    • 62749107947 scopus 로고    scopus 로고
    • Gag p27-specific B- and T-cell responses in Simian immunodeficiency virus SIVagm-infected African green monkeys
    • Lozano Reina JM, Favre D, Kasakow Z, et al. Gag p27-specific B- and T-cell responses in Simian immunodeficiency virus SIVagm-infected African green monkeys. J Virol 2009; 83: 2770-2777.
    • (2009) J Virol , vol.83 , pp. 2770-2777
    • Lozano Reina, J.M.1    Favre, D.2    Kasakow, Z.3
  • 29
    • 84866978487 scopus 로고    scopus 로고
    • Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV-1 infection
    • Liovat AS, Rey-Cuille MA, Lecuroux C, et al. Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV-1 infection. PLoS ONE 2012; 7: e46143.
    • (2012) PLoS ONE , vol.7 , pp. e46143
    • Liovat, A.S.1    Rey-Cuille, M.A.2    Lecuroux, C.3
  • 30
    • 84911432282 scopus 로고    scopus 로고
    • Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals
    • Klatt NR, Bosinger SE, Peck M, et al. Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals. PLoS Pathog 2014; 10: e1004345.
    • (2014) PLoS Pathog , vol.10 , pp. e1004345
    • Klatt, N.R.1    Bosinger, S.E.2    Peck, M.3
  • 31
    • 77949565615 scopus 로고    scopus 로고
    • Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression
    • Roberts L, Passmore JA, Williamson C, et al. Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression. Aids 2010; 24: 819-831.
    • (2010) AIDS , vol.24 , pp. 819-831
    • Roberts, L.1    Passmore, J.A.2    Williamson, C.3
  • 33
    • 77956906960 scopus 로고    scopus 로고
    • Effect of a short-term HAART on SIV load in macaque tissues is dependent on time of initiation and antiviral diffusion
    • Bourry O, Mannioui A, Sellier P, et al. Effect of a short-term HAART on SIV load in macaque tissues is dependent on time of initiation and antiviral diffusion. Retrovirology 2010; 7: 78.
    • (2010) Retrovirology , vol.7 , pp. 78
    • Bourry, O.1    Mannioui, A.2    Sellier, P.3
  • 34
    • 53449093632 scopus 로고    scopus 로고
    • Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections
    • Brenchley JM, Paiardini M, Knox KS, et al. Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections. Blood 2008; 112: 2826-2835.
    • (2008) Blood , vol.112 , pp. 2826-2835
    • Brenchley, J.M.1    Paiardini, M.2    Knox, K.S.3
  • 35
    • 58149177783 scopus 로고    scopus 로고
    • Cutting edge: Experimentally induced immune activation in natural hosts of simian immunodeficiency virus induces significant increases in viral replication and CD4+ T cell depletion
    • Pandrea I, Gaufin T, Brenchley JM, et al. Cutting edge: experimentally induced immune activation in natural hosts of simian immunodeficiency virus induces significant increases in viral replication and CD4+ T cell depletion. J Immunol 2008; 181: 6687-6691.
    • (2008) J Immunol , vol.181 , pp. 6687-6691
    • Pandrea, I.1    Gaufin, T.2    Brenchley, J.M.3
  • 36
    • 84939515008 scopus 로고    scopus 로고
    • Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection
    • Hao XP, Lucero CM, Turkbey B, et al. Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection. Nat Commun 2015; 6: 8020.
    • (2015) Nat Commun , vol.6 , pp. 8020
    • Hao, X.P.1    Lucero, C.M.2    Turkbey, B.3
  • 37
    • 45449104669 scopus 로고    scopus 로고
    • Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques
    • Cecchinato V, Trindade CJ, Laurence A, et al. Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques. Mucosal Immunol 2008; 1: 279-288.
    • (2008) Mucosal Immunol , vol.1 , pp. 279-288
    • Cecchinato, V.1    Trindade, C.J.2    Laurence, A.3
  • 38
    • 84872174074 scopus 로고    scopus 로고
    • Microbial translocation in the pathogenesis of HIV infection and AIDS
    • Marchetti G, Tincati C, Silvestri G. Microbial translocation in the pathogenesis of HIV infection and AIDS. Clin Microbiol Rev 2013; 26: 2-18.
    • (2013) Clin Microbiol Rev , vol.26 , pp. 2-18
    • Marchetti, G.1    Tincati, C.2    Silvestri, G.3
  • 39
    • 84919665923 scopus 로고    scopus 로고
    • Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation
    • Rv254/Search, and R.S.S. Groups
    • J. Ananworanich, Rv254/Search, and R.S.S. Groups. Schuetz A, Deleage C, Sereti I, et al. Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation. PLoS Pathog 2014; 10: e1004543.
    • (2014) PLoS Pathog , vol.10 , pp. e1004543
    • Ananworanich, J.1    Schuetz, A.2    Deleage, C.3    Sereti, I.4
  • 40
    • 84957444916 scopus 로고    scopus 로고
    • IL-21 and probiotic therapy improve Th17 frequencies, microbial translocation, and microbiome in ARV-treated, SIV-infected macaques
    • Ortiz AM, Klase ZA, DiNapoli SR, et al. IL-21 and probiotic therapy improve Th17 frequencies, microbial translocation, and microbiome in ARV-treated, SIV-infected macaques. Mucosal Immunol 2015.
    • (2015) Mucosal Immunol
    • Ortiz, A.M.1    Klase, Z.A.2    DiNapoli, S.R.3
  • 41
    • 68349125557 scopus 로고    scopus 로고
    • CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection
    • Beaumier CM, Harris LD, Goldstein S, et al. CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection. Nat Med 2009; 15: 879-885.
    • (2009) Nat Med , vol.15 , pp. 879-885
    • Beaumier, C.M.1    Harris, L.D.2    Goldstein, S.3
  • 42
    • 0030969954 scopus 로고    scopus 로고
    • CD4 and CD8 expressions in African green monkey helper T lymphocytes: Implication for resistance to SIV infection
    • Murayama Y, Amano A, Mukai R, et al. CD4 and CD8 expressions in African green monkey helper T lymphocytes: implication for resistance to SIV infection. Int Immunol 1997; 9: 843-851.
    • (1997) Int Immunol , vol.9 , pp. 843-851
    • Murayama, Y.1    Amano, A.2    Mukai, R.3
  • 43
    • 84901255278 scopus 로고    scopus 로고
    • Divergent CD4+ T memory stem cell dynamics in pathogenic and nonpathogenic simian immunodeficiency virus infections
    • Cartwright EK, McGary CS, Cervasi B, et al. Divergent CD4+ T memory stem cell dynamics in pathogenic and nonpathogenic simian immunodeficiency virus infections. J Immunol 2014; 192: 4666-4673.
    • (2014) J Immunol , vol.192 , pp. 4666-4673
    • Cartwright, E.K.1    McGary, C.S.2    Cervasi, B.3
  • 44
    • 79960131812 scopus 로고    scopus 로고
    • Low levels of SIV infection in sooty mangabey central memory CD (4)(+) T cells are associated with limited CCR5 expression
    • Paiardini M, Cervasi B, Reyes-Aviles E, et al. Low levels of SIV infection in sooty mangabey central memory CD (4)(+) T cells are associated with limited CCR5 expression. Nat Med 2011; 17: 830-836.
    • (2011) Nat Med , vol.17 , pp. 830-836
    • Paiardini, M.1    Cervasi, B.2    Reyes-Aviles, E.3
  • 45
    • 84897005969 scopus 로고    scopus 로고
    • Increased stability and limited proliferation of CD4+ central memory T cells differentiate nonprogressive simian immunodeficiency virus (SIV) infection of sooty mangabeys from progressive SIV infection of rhesus macaques
    • McGary CS, Cervasi B, Chahroudi A, et al. Increased stability and limited proliferation of CD4+ central memory T cells differentiate nonprogressive simian immunodeficiency virus (SIV) infection of sooty mangabeys from progressive SIV infection of rhesus macaques. J Virol 2014; 88: 4533-4542.
    • (2014) J Virol , vol.88 , pp. 4533-4542
    • McGary, C.S.1    Cervasi, B.2    Chahroudi, A.3
  • 46
    • 84860255621 scopus 로고    scopus 로고
    • Immune responses driven by protective human leukocyte antigen alleles from long-term nonprogressors are associated with low HIV reservoir in central memory CD4 T cells
    • Descours B, Avettand-Fenoel V, Blanc C, et al. Immune responses driven by protective human leukocyte antigen alleles from long-term nonprogressors are associated with low HIV reservoir in central memory CD4 T cells. Clin Infect Dis 2012; 54: 1495-1503.
    • (2012) Clin Infect Dis , vol.54 , pp. 1495-1503
    • Descours, B.1    Avettand-Fenoel, V.2    Blanc, C.3
  • 47
    • 84875985311 scopus 로고    scopus 로고
    • Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study
    • Saez-Cirion A, Bacchus C, Hocqueloux L, et al. Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study. PLoS Pathog 2013; 9: e1003211.
    • (2013) PLoS Pathog , vol.9 , pp. e1003211
    • Saez-Cirion, A.1    Bacchus, C.2    Hocqueloux, L.3
  • 48
    • 84942155308 scopus 로고    scopus 로고
    • Reduced simian immunodeficiency virus replication in macrophages of sooty mangabeys is associated with increased expression of host restriction factors
    • Mir KD, Mavigner M, Wang C, et al. Reduced simian immunodeficiency virus replication in macrophages of sooty mangabeys is associated with increased expression of host restriction factors. J Virol 2015; 89: 10136-10144.
    • (2015) J Virol , vol.89 , pp. 10136-10144
    • Mir, K.D.1    Mavigner, M.2    Wang, C.3
  • 49
    • 80053944260 scopus 로고    scopus 로고
    • Differential innate immune responses to low or high dose oral SIV challenge in rhesus macaques
    • Durudas A, Chen HL, Gasper MA, et al. Differential innate immune responses to low or high dose oral SIV challenge in rhesus macaques. Current HIV research 2011; 9: 276-288.
    • (2011) Current HIV Research , vol.9 , pp. 276-288
    • Durudas, A.1    Chen, H.L.2    Gasper, M.A.3
  • 50
    • 70450159576 scopus 로고    scopus 로고
    • Elevated levels of innate immune modulators in lymph nodes and blood are associated with more-rapid disease progression in simian immunodeficiency virus-infected monkeys
    • Durudas A, Milush JM, Chen HL, et al. Elevated levels of innate immune modulators in lymph nodes and blood are associated with more-rapid disease progression in simian immunodeficiency virus-infected monkeys. J Virol 2009; 83: 12229-12240.
    • (2009) J Virol , vol.83 , pp. 12229-12240
    • Durudas, A.1    Milush, J.M.2    Chen, H.L.3
  • 51
    • 39049122116 scopus 로고    scopus 로고
    • Virologic and immunologic events in hilar lymph nodes during simian immunodeficiency virus infection: Development of polarized inflammation
    • Fallert BA, Poveda S, Schaefer TM, et al. Virologic and immunologic events in hilar lymph nodes during simian immunodeficiency virus infection: development of polarized inflammation. J Acquir Immune Defic Syndr 2008; 47: 16-26.
    • (2008) J Acquir Immune Defic Syndr , vol.47 , pp. 16-26
    • Fallert, B.A.1    Poveda, S.2    Schaefer, T.M.3
  • 52
    • 0042974103 scopus 로고    scopus 로고
    • Expression of IFN-gamma induced CXCR3 agonist chemokines and compartmentalization of CXCR3+ cells in the periphery and lymph nodes of rhesus macaques during simian immunodeficiency virus infection and acquired immunodeficiency syndrome
    • Sarkar S, Kalia V, Murphey-Corb M, et al. Expression of IFN-gamma induced CXCR3 agonist chemokines and compartmentalization of CXCR3+ cells in the periphery and lymph nodes of rhesus macaques during simian immunodeficiency virus infection and acquired immunodeficiency syndrome. J Med Primatol 2003; 32: 247-264.
    • (2003) J Med Primatol , vol.32 , pp. 247-264
    • Sarkar, S.1    Kalia, V.2    Murphey-Corb, M.3
  • 53
    • 38849134878 scopus 로고    scopus 로고
    • Chronic CD4+ T-cell activation and depletion in human immunodeficiency virus type 1 infection: Type i interferon- mediated disruption of T-cell dynamics
    • Sedaghat AR, German J, Teslovich TM, et al. Chronic CD4+ T-cell activation and depletion in human immunodeficiency virus type 1 infection: type I interferon- mediated disruption of T-cell dynamics. J Virol 2008; 82: 1870-1883.
    • (2008) J Virol , vol.82 , pp. 1870-1883
    • Sedaghat, A.R.1    German, J.2    Teslovich, T.M.3
  • 54
    • 84862491847 scopus 로고    scopus 로고
    • Treatment of SIV-infected sooty mangabeys with a type-I IFN agonist results in decreased virus replication without inducing hyperimmune activation
    • Vanderford TH, Slichter C, Rogers KA, et al. Treatment of SIV-infected sooty mangabeys with a type-I IFN agonist results in decreased virus replication without inducing hyperimmune activation. Blood 2012; 119: 5750-5757.
    • (2012) Blood , vol.119 , pp. 5750-5757
    • Vanderford, T.H.1    Slichter, C.2    Rogers, K.A.3
  • 55
    • 84901933676 scopus 로고    scopus 로고
    • Type i interferon responses in rhesus macaques prevent SIV infection and slow disease progression
    • Sandler NG, Bosinger SE, Estes JD, et al. Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression. Nature 2014; 511: 601-605.
    • (2014) Nature , vol.511 , pp. 601-605
    • Sandler, N.G.1    Bosinger, S.E.2    Estes, J.D.3
  • 56
    • 61449229744 scopus 로고    scopus 로고
    • Transcriptional profiling in pathogenic and nonpathogenic SIV infections reveals significant distinctions in kinetics and tissue compartmentalization
    • Lederer S, Favre D, Walters KA, et al. Transcriptional profiling in pathogenic and nonpathogenic SIV infections reveals significant distinctions in kinetics and tissue compartmentalization. PLoS Pathog 2009; 5: e1000296.
    • (2009) PLoS Pathog , vol.5 , pp. e1000296
    • Lederer, S.1    Favre, D.2    Walters, K.A.3
  • 57
    • 72849136282 scopus 로고    scopus 로고
    • Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type i IFN response
    • Jacquelin B, Mayau V, Targat B, et al. Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response. J Clin Invest 2009; 119: 3544-3555.
    • (2009) J Clin Invest , vol.119 , pp. 3544-3555
    • Jacquelin, B.1    Mayau, V.2    Targat, B.3
  • 58
    • 84867521316 scopus 로고    scopus 로고
    • Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome
    • Handley SA, Thackray LB, Zhao G, et al. Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome. Cell 2012; 151: 253-266.
    • (2012) Cell , vol.151 , pp. 253-266
    • Handley, S.A.1    Thackray, L.B.2    Zhao, G.3
  • 59
    • 78650962504 scopus 로고    scopus 로고
    • Evidence for an antagonist form of the chemokine CXCL10 in patients chronically infected with HCV
    • Casrouge A, Decalf J, Ahloulay M, et al. Evidence for an antagonist form of the chemokine CXCL10 in patients chronically infected with HCV. J Clin Invest 2011; 121: 308-317.
    • (2011) J Clin Invest , vol.121 , pp. 308-317
    • Casrouge, A.1    Decalf, J.2    Ahloulay, M.3
  • 60
    • 77956555588 scopus 로고    scopus 로고
    • Simian immunodeficiency virus infection alters chemokine networks in lung tissues of cynomolgus macaques: Association with Pneumocystis carinii infection
    • Qin S, Fallert Junecko BA, Trichel AM, et al. Simian immunodeficiency virus infection alters chemokine networks in lung tissues of cynomolgus macaques: association with Pneumocystis carinii infection. Am J Pathol 2010; 177: 1274-1285.
    • (2010) Am J Pathol , vol.177 , pp. 1274-1285
    • Qin, S.1    Fallert Junecko, B.A.2    Trichel, A.M.3
  • 61
    • 84880199166 scopus 로고    scopus 로고
    • Simian immunodeficiency virus infection potently modulates chemokine networks and immune environments in hilar lymph nodes of cynomolgus macaques
    • Qin S, Junecko BA, Lucero CM, et al. Simian immunodeficiency virus infection potently modulates chemokine networks and immune environments in hilar lymph nodes of cynomolgus macaques. J Acquir Immune Defic Syndr 2013; 63: 428-437.
    • (2013) J Acquir Immune Defic Syndr , vol.63 , pp. 428-437
    • Qin, S.1    Junecko, B.A.2    Lucero, C.M.3
  • 62
    • 84937711740 scopus 로고    scopus 로고
    • Codelivery of envelope protein in alum with MVA vaccine induces CXCR3-biased CXCR5+and CXCR5- CD4 T cell responses in rhesus macaques
    • Iyer SS, Gangadhara S, Victor B, et al. Codelivery of envelope protein in alum with MVA vaccine induces CXCR3-biased CXCR5+and CXCR5- CD4 T cell responses in rhesus macaques. J Immunol 2015; 195: 994-1005.
    • (2015) J Immunol , vol.195 , pp. 994-1005
    • Iyer, S.S.1    Gangadhara, S.2    Victor, B.3
  • 63
    • 77958485320 scopus 로고    scopus 로고
    • Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton
    • Cameron PU, Saleh S, Sallmann G, et al. Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton. Proc Natl Acad Sci U S A 2010; 107: 16934-16939.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 16934-16939
    • Cameron, P.U.1    Saleh, S.2    Sallmann, G.3
  • 64
    • 84869814713 scopus 로고    scopus 로고
    • Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections
    • Brenchley JM, Vinton C, Tabb B, et al. Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections. Blood 2012; 120: 4172-4181.
    • (2012) Blood , vol.120 , pp. 4172-4181
    • Brenchley, J.M.1    Vinton, C.2    Tabb, B.3
  • 65
    • 0029888531 scopus 로고    scopus 로고
    • Lack of dichotomy between virus load of peripheral blood and lymph nodes during long-term simian immunodeficiency virus infection of African green monkeys
    • Beer B, Scherer J, Megede JZ, et al. Lack of dichotomy between virus load of peripheral blood and lymph nodes during long-term simian immunodeficiency virus infection of African green monkeys. Virology 1996; 219: 367.
    • (1996) Virology , vol.219 , pp. 367
    • Beer, B.1    Scherer, J.2    Megede, J.Z.3
  • 66
    • 0028168755 scopus 로고
    • Variable course of primary simian immunodeficiency virus infection in lymph nodes: Relation to disease progression
    • Chakrabarti L, Cumont MC, Montagnier L, Hurtrel B. Variable course of primary simian immunodeficiency virus infection in lymph nodes: relation to disease progression. J Virol 1994; 68: 6634-6643.
    • (1994) J Virol , vol.68 , pp. 6634-6643
    • Chakrabarti, L.1    Cumont, M.C.2    Montagnier, L.3    Hurtrel, B.4
  • 67
    • 38349162886 scopus 로고    scopus 로고
    • Early divergence in lymphoid tissue apoptosis between pathogenic and nonpathogenic simian immunodeficiency virus infections of nonhuman primates
    • Cumont MC, Diop O, Vaslin B, et al. Early divergence in lymphoid tissue apoptosis between pathogenic and nonpathogenic simian immunodeficiency virus infections of nonhuman primates. J Virol 2008; 82: 1175-1184.
    • (2008) J Virol , vol.82 , pp. 1175-1184
    • Cumont, M.C.1    Diop, O.2    Vaslin, B.3
  • 68
    • 45549092692 scopus 로고    scopus 로고
    • Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques
    • Estes JD, Gordon SN, Zeng M, et al. Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques. J Immunol 2008; 180: 6798-6807.
    • (2008) J Immunol , vol.180 , pp. 6798-6807
    • Estes, J.D.1    Gordon, S.N.2    Zeng, M.3
  • 69
    • 16244408954 scopus 로고    scopus 로고
    • Plateau levels of viremia correlate with the degree of CD4+-T-cell loss in simian immunodeficiency virus SIVagm-infected pigtailed macaques: Variable pathogenicity of natural SIVagm isolates
    • Goldstein S, Ourmanov I, Brown CR, et al. Plateau levels of viremia correlate with the degree of CD4+-T-cell loss in simian immunodeficiency virus SIVagm-infected pigtailed macaques: variable pathogenicity of natural SIVagm isolates. J Virol 2005; 79: 5153-5162.
    • (2005) J Virol , vol.79 , pp. 5153-5162
    • Goldstein, S.1    Ourmanov, I.2    Brown, C.R.3
  • 70
    • 84874584768 scopus 로고    scopus 로고
    • Acute SIV infection in sooty mangabey monkeys is characterized by rapid virus clearance from lymph nodes and absence of productive infection in germinal centers
    • Martinot AJ, Meythaler M, Pozzi LA, et al. Acute SIV infection in sooty mangabey monkeys is characterized by rapid virus clearance from lymph nodes and absence of productive infection in germinal centers. PLoS One 2013; 8: e57785.
    • (2013) PLoS One , vol.8 , pp. e57785
    • Martinot, A.J.1    Meythaler, M.2    Pozzi, L.A.3
  • 71
    • 79955534580 scopus 로고    scopus 로고
    • Early induction of polyfunctional simian immunodeficiency virus (SIV)-specific T lymphocytes and rapid disappearance of SIV from lymph nodes of sooty mangabeys during primary infection
    • MeythalerM, Wang Z, Martinot A, et al. Early induction of polyfunctional simian immunodeficiency virus (SIV)-specific T lymphocytes and rapid disappearance of SIV from lymph nodes of sooty mangabeys during primary infection. J Immunol 2011; 186: 5151-5161.
    • (2011) J Immunol , vol.186 , pp. 5151-5161
    • Meythaler, M.1    Wang, Z.2    Martinot, A.3
  • 72
    • 0029888531 scopus 로고    scopus 로고
    • Lack of dichotomy between virus load of peripheral blood and lymph nodes during long-term simian immunodeficiency virus infection of African green monkeys
    • Beer B, Scherer J, zur Megede J, et al. Lack of dichotomy between virus load of peripheral blood and lymph nodes during long-term simian immunodeficiency virus infection of African green monkeys. Virology 1996; 219: 367-375.
    • (1996) Virology , vol.219 , pp. 367-375
    • Beer, B.1    Scherer, J.2    Zur Megede, J.3
  • 73
    • 0036786450 scopus 로고    scopus 로고
    • High levels of viral replication contrast with only transient changes in CD4+ and CD8+ cell numbers during the early phase of experimental infection with SIVmnd-1 in Mandrillus sphinx
    • Onanga R, Kornfeld C, Pandrea I, et al. High levels of viral replication contrast with only transient changes in CD4+ and CD8+ cell numbers during the early phase of experimental infection with SIVmnd-1 in Mandrillus sphinx. J Virol 2002; 76: 10256-10263.
    • (2002) J Virol , vol.76 , pp. 10256-10263
    • Onanga, R.1    Kornfeld, C.2    Pandrea, I.3
  • 74
    • 33846785628 scopus 로고    scopus 로고
    • Simian immunodeficiency virusinduced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection
    • Estes JD, Wietgrefe S, Schacker T, et al. Simian immunodeficiency virusinduced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection. J Infect Dis 2007; 195: 551-561.
    • (2007) J Infect Dis , vol.195 , pp. 551-561
    • Estes, J.D.1    Wietgrefe, S.2    Schacker, T.3
  • 75
    • 84879302220 scopus 로고    scopus 로고
    • Pathobiology of HIV/SIV-associated changes in secondary lymphoid tissues
    • Estes JD. Pathobiology of HIV/SIV-associated changes in secondary lymphoid tissues. Immunol Rev 2013; 254: 65-77.
    • (2013) Immunol Rev , vol.254 , pp. 65-77
    • Estes, J.D.1
  • 76
    • 84857479601 scopus 로고    scopus 로고
    • Lymphoid tissue damage in HIV-1 infection depletes naive T cells and limits T cell reconstitution after antiretroviral therapy
    • Zeng M, Southern PJ, Reilly CS, et al. Lymphoid tissue damage in HIV-1 infection depletes naive T cells and limits T cell reconstitution after antiretroviral therapy. PLoS Pathog 2012; 8: e1002437.
    • (2012) PLoS Pathog , vol.8 , pp. e1002437
    • Zeng, M.1    Southern, P.J.2    Reilly, C.S.3
  • 77
    • 84893830170 scopus 로고    scopus 로고
    • Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues
    • Fletcher CV, Staskus K, Wietgrefe SW, et al. Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues. Proc Natl Acad Sci U S A 2014; 111: 2307-2312.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 2307-2312
    • Fletcher, C.V.1    Staskus, K.2    Wietgrefe, S.W.3
  • 78
    • 84940530289 scopus 로고    scopus 로고
    • Initiation of antiretroviral therapy in early asymptomatic HIV infection
    • Lundgren JD, Babiker AG, Gordin F, et al. Initiation of antiretroviral therapy in early asymptomatic HIV infection. N Engl J Med 2015; 373: 795-807.
    • (2015) N Engl J Med , vol.373 , pp. 795-807
    • Lundgren, J.D.1    Babiker, A.G.2    Gordin, F.3
  • 79
    • 84897965706 scopus 로고    scopus 로고
    • HIV cure research: Advances and prospects
    • Passaes CP, Saez-Cirion A. HIV cure research: advances and prospects. Virology 2014; 454-455: 340-352.
    • (2014) Virology , vol.454-455 , pp. 340-352
    • Passaes, C.P.1    Saez-Cirion, A.2


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