Inhibition of lysosomal protease cathepsin D reduces renal fibrosis in murine chronic kidney disease

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Fox, Christopher ^a   Cocchiaro, Pasquale ^a,b   Oakley, Fiona ^a   Howarth, Rachel ^a   Callaghan, Krystena ^a   Leslie, Jack ^a   Luli, Saimir ^a   Wood, Katrina M ^c   Genovese, Federica ^d   Sheerin, Neil S ^a   Moles, Anna ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c ROYAL VICTORIA INFIRMARY   (United Kingdom)

^d NORDIC BIOSCIENCE A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CA 074 METHYL ESTER; CATHEPSIN D; CHLOROQUINE; COLLAGEN; CTSD PROTEIN, MOUSE; DIPEPTIDE; PEPSTATIN;

ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DISEASE MODEL; ENZYMOLOGY; EXTRACELLULAR MATRIX; FEMALE; FIBROSIS; HUMAN; LYSOSOME; METABOLISM; MOUSE; MYOFIBROBLAST; PATHOLOGY; RENAL INSUFFICIENCY, CHRONIC;

ANIMALS; CATHEPSIN D; CHLOROQUINE; COLLAGEN; DIPEPTIDES; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX; FEMALE; FIBROSIS; HUMANS; LYSOSOMES; MICE; MYOFIBROBLASTS; PEPSTATINS; RENAL INSUFFICIENCY, CHRONIC;

EID: 84957599203     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep20101     Document Type: Article

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