메뉴 건너뛰기




Volumn 12, Issue 4, 2016, Pages 397-408

Mir-487a promotes TGF-β1-induced EMT, the migration and invasion of breast cancer cells by directly targeting MAGI2

Author keywords

Breast cancer; EMT; MAGI2; MiR 487a; p65; TGF 1

Indexed keywords

CARRIER PROTEIN; MAGI2 PROTEIN, HUMAN; MICRORNA; MIRN487 MICRORNA, HUMAN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84957568728     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.13475     Document Type: Article
Times cited : (61)

References (33)
  • 2
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-Mesenchymal Transitions in Development and Disease
    • Thiery JP, Acloque H, Huang RYJ, Nieto MA: Epithelial-Mesenchymal Transitions in Development and Disease. Cell 2009, 139(5):871-890.
    • (2009) Cell , vol.139 , Issue.5 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.3    Nieto, M.A.4
  • 3
    • 14844364701 scopus 로고    scopus 로고
    • Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity
    • Ozdamar B, Bose R, Barrios-Rodiles M, Wang HR, Zhang Y, Wrana JL: Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity. Science 2005, 307(5715):1603-1609.
    • (2005) Science , vol.307 , Issue.5715 , pp. 1603-1609
    • Ozdamar, B.1    Bose, R.2    Barrios-Rodiles, M.3    Wang, H.R.4    Zhang, Y.5    Wrana, J.L.6
  • 4
    • 0038106228 scopus 로고    scopus 로고
    • Regulation of tight junctions during the epithelium-mesenchyme transition: Direct repression of the gene expression of claudins/occludin by Snail
    • Ikenouchi J: Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail. Journal of Cell Science 2003, 116(10):1959-1967.
    • (2003) Journal of Cell Science , vol.116 , Issue.10 , pp. 1959-1967
    • Ikenouchi, J.1
  • 6
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
    • Yang J, Weinberg RA: Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis. Developmental Cell 2008, 14(6):818-829.
    • (2008) Developmental Cell , vol.14 , Issue.6 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2
  • 7
    • 59449090107 scopus 로고    scopus 로고
    • TGF-β-induced epithelial to mesenchymal transition
    • Xu J, Lamouille S, Derynck R: TGF-β-induced epithelial to mesenchymal transition. Cell Research 2009, 19(2):156-172.
    • (2009) Cell Research , vol.19 , Issue.2 , pp. 156-172
    • Xu, J.1    Lamouille, S.2    Derynck, R.3
  • 8
    • 0034711307 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-Kinase Function Is Required for Transforming Growth Factor-mediated Epithelial to Mesenchymal Transition and Cell Migration
    • Bakin AV, Tomlinson AK, Bhowmick NA, Moses HL, Arteaga CL: Phosphatidylinositol 3-Kinase Function Is Required for Transforming Growth Factor-mediated Epithelial to Mesenchymal Transition and Cell Migration. Journal of Biological Chemistry 2000, 275(47):36803-36810.
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.47 , pp. 36803-36810
    • Bakin, A.V.1    Tomlinson, A.K.2    Bhowmick, N.A.3    Moses, H.L.4    Arteaga, C.L.5
  • 9
    • 84862994787 scopus 로고    scopus 로고
    • Transforming growth factor-β1 induces epithelial-to-mesenchymal transition in human lung cancer cells via PI3K/Akt and MEK/Erk1/2 signaling pathways
    • Chen X-F, Zhang H-J, Wang H-B, Zhu J, Zhou W-Y, Zhang H, Zhao M-C, Su J-M, Gao W, Zhang L et al: Transforming growth factor-β1 induces epithelial-to-mesenchymal transition in human lung cancer cells via PI3K/Akt and MEK/Erk1/2 signaling pathways. Molecular Biology Reports 2011, 39(4):3549-3556.
    • (2011) Molecular Biology Reports , vol.39 , Issue.4 , pp. 3549-3556
    • Chen, X.-F.1    Zhang, H.-J.2    Wang, H.-B.3    Zhu, J.4    Zhou, W.-Y.5    Zhang, H.6    Zhao, M.-C.7    Su, J.-M.8    Gao, W.9    Zhang, L.10
  • 10
    • 47249091921 scopus 로고    scopus 로고
    • The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2
    • Korpal M, Lee ES, Hu G, Kang Y: The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2. Journal of Biological Chemistry 2008, 283(22):14910-14914.
    • (2008) Journal of Biological Chemistry , vol.283 , Issue.22 , pp. 14910-14914
    • Korpal, M.1    Lee, E.S.2    Hu, G.3    Kang, Y.4
  • 11
    • 84894275355 scopus 로고    scopus 로고
    • Critical role of miR-10b in transforming growth factor-β1-induced epithelial–mesenchymal transition in breast cancer
    • Han X, Yan S, Weijie Z, Feng W, Liuxing W, Mengquan L, Qingxia F: Critical role of miR-10b in transforming growth factor-β1-induced epithelial–mesenchymal transition in breast cancer. Cancer Gene Therapy 2014, 21(2):60-67.
    • (2014) Cancer Gene Therapy , vol.21 , Issue.2 , pp. 60-67
    • Han, X.1    Yan, S.2    Weijie, Z.3    Feng, W.4    Liuxing, W.5    Mengquan, L.6    Qingxia, F.7
  • 14
    • 84883449522 scopus 로고    scopus 로고
    • MiR-487a resensitizes mitoxantrone (MX)-resistant breast cancer cells (MCF-7/MX) to MX by targeting breast cancer resistance protein (BCRP/ABCG2)
    • Ma M-T, He M, Wang Y, Jiao X-Y, Zhao L, Bai X-F, Yu Z-J, Wu H-Z, Sun M-L, Song Z-G et al: MiR-487a resensitizes mitoxantrone (MX)-resistant breast cancer cells (MCF-7/MX) to MX by targeting breast cancer resistance protein (BCRP/ABCG2). Cancer Letters 2013, 339(1):107-115.
    • (2013) Cancer Letters , vol.339 , Issue.1 , pp. 107-115
    • Ma, M.-T.1    He, M.2    Wang, Y.3    Jiao, X.-Y.4    Zhao, L.5    Bai, X.-F.6    Yu, Z.-J.7    Wu, H.-Z.8    Sun, M.-L.9    Song, Z.-G.10
  • 15
    • 84877037101 scopus 로고    scopus 로고
    • Activin and TGFβ regulate expression of the microRNA-181 family to promote cell migration and invasion in breast cancer cells
    • Neel J-C, Lebrun J-J: Activin and TGFβ regulate expression of the microRNA-181 family to promote cell migration and invasion in breast cancer cells. Cellular Signalling 2013, 25(7):1556-1566.
    • (2013) Cellular Signalling , vol.25 , Issue.7 , pp. 1556-1566
    • Neel, J.-C.1    Lebrun, J.-J.2
  • 16
    • 84910141016 scopus 로고    scopus 로고
    • Metastatic heterogeneity of breast cancer cells is associated with expression of a heterogeneous TGFbeta-activating miR424-503 gene cluster
    • Li Y, Li W, Ying Z, Tian H, Zhu X, Li J, Li M: Metastatic heterogeneity of breast cancer cells is associated with expression of a heterogeneous TGFbeta-activating miR424-503 gene cluster. Cancer research 2014, 74(21):6107-6118.
    • (2014) Cancer Research , vol.74 , Issue.21 , pp. 6107-6118
    • Li, Y.1    Li, W.2    Ying, Z.3    Tian, H.4    Zhu, X.5    Li, J.6    Li, M.7
  • 17
    • 84938979964 scopus 로고    scopus 로고
    • DNA methyltransferase 1/3a overexpression in sporadic breast cancer is associated with reduced expression of estrogen receptor-alpha/breast cancer susceptibility gene 1 and poor prognosis
    • Yu Z, Xiao Q, Zhao L, Ren J, Bai X, Sun M, Wu H, Liu X, Song Z, Yan Y et al: DNA methyltransferase 1/3a overexpression in sporadic breast cancer is associated with reduced expression of estrogen receptor-alpha/breast cancer susceptibility gene 1 and poor prognosis. Molecular Carcinogenesis 2014.
    • (2014) Molecular Carcinogenesis
    • Yu, Z.1    Xiao, Q.2    Zhao, L.3    Ren, J.4    Bai, X.5    Sun, M.6    Wu, H.7    Liu, X.8    Song, Z.9    Yan, Y.10
  • 18
    • 23844473290 scopus 로고    scopus 로고
    • Binding of PTEN to Specific PDZ Domains Contributes to PTEN Protein Stability and Phosphorylation by Microtubule-associated Serine/Threonine Kinases
    • Valiente M: Binding of PTEN to Specific PDZ Domains Contributes to PTEN Protein Stability and Phosphorylation by Microtubule-associated Serine/Threonine Kinases. Journal of Biological Chemistry 2005, 280(32):28936-28943.
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.32 , pp. 28936-28943
    • Valiente, M.1
  • 20
    • 59449090107 scopus 로고    scopus 로고
    • TGF-beta-induced epithelial to mesenchymal transition
    • Xu J, Lamouille S, Derynck R: TGF-beta-induced epithelial to mesenchymal transition. Cell research 2009, 19(2):156-172.
    • (2009) Cell Research , vol.19 , Issue.2 , pp. 156-172
    • Xu, J.1    Lamouille, S.2    Derynck, R.3
  • 23
    • 84929120362 scopus 로고    scopus 로고
    • MicroRNA Expression Profiling in Clear Cell Renal Cell Carcinoma: Identification and Functional Validation of Key miRNAs
    • He H, Wang L, Zhou W, Zhang Z, Xu S, Wang D, Dong J, Tang C, Tang H, Yi X et al: MicroRNA Expression Profiling in Clear Cell Renal Cell Carcinoma: Identification and Functional Validation of Key miRNAs. PloS one 2015, 10(5):e0125672.
    • (2015) Plos One , vol.10 , Issue.5
    • He, H.1    Wang, L.2    Zhou, W.3    Zhang, Z.4    Xu, S.5    Wang, D.6    Dong, J.7    Tang, C.8    Tang, H.9    Yi, X.10
  • 24
    • 84908622005 scopus 로고    scopus 로고
    • Altered Serum MicroRNAs as Novel Diagnostic Biomarkers for Atypical Coronary Artery Disease
    • Wang J, Pei YH, Zhong Y, Jiang SS, Shao JQ, Gong JB: Altered Serum MicroRNAs as Novel Diagnostic Biomarkers for Atypical Coronary Artery Disease. PloS one 2014, 9(9).
    • (2014) Plos One , vol.9 , Issue.9
    • Wang, J.1    Pei, Y.H.2    Zhong, Y.3    Jiang, S.S.4    Shao, J.Q.5    Gong, J.B.6
  • 25
    • 77949445582 scopus 로고    scopus 로고
    • MicroRNA-181a sensitizes human malignant glioma U87MG cells to radiation by targeting Bcl-2
    • Chen G, Zhu W, Shi D, Lv L, Zhang C, Liu P, Hu W: MicroRNA-181a sensitizes human malignant glioma U87MG cells to radiation by targeting Bcl-2. Oncology Reports 2010, 23(4).
    • (2010) Oncology Reports , vol.23 , Issue.4
    • Chen, G.1    Zhu, W.2    Shi, D.3    Lv, L.4    Zhang, C.5    Liu, P.6    Hu, W.7
  • 26
    • 79953043006 scopus 로고    scopus 로고
    • Transforming growth factor β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM
    • Wang Y, et al. Transforming growth factor β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM. Oncogene 2011.
    • (2011) Oncogene
    • Wang, Y.1
  • 28
    • 77950095763 scopus 로고    scopus 로고
    • TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3
    • Wang B, Hsu SH, Majumder S, Kutay H, Huang W, Jacob ST, Ghoshal K: TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3. Oncogene 2009, 29(12):1787-1797.
    • (2009) Oncogene , vol.29 , Issue.12 , pp. 1787-1797
    • Wang, B.1    Hsu, S.H.2    Majumder, S.3    Kutay, H.4    Huang, W.5    Jacob, S.T.6    Ghoshal, K.7
  • 29
    • 71049175699 scopus 로고    scopus 로고
    • Hematopoiesis-related microRNA expression in myelodysplastic syndromes
    • Pons A ea: Hematopoiesis-related microRNA expression in myelodysplastic syndromes. Leuk Lymphoma 2009, 50(11):1854–1859.
    • (2009) Leuk Lymphoma , vol.50 , Issue.11 , pp. 1854-1859
    • Pons, A.1
  • 32
    • 84894206438 scopus 로고    scopus 로고
    • MiR-134/487b/655 Cluster Regulates TGF--Induced Epithelial-Mesenchymal Transition and Drug Resistance to Gefitinib by Targeting MAGI2 in Lung Adenocarcinoma Cells
    • Kitamura K, Seike M, Okano T, Matsuda K, Miyanaga A, Mizutani H, Noro R, Minegishi Y, Kubota K, Gemma A: MiR-134/487b/655 Cluster Regulates TGF--Induced Epithelial-Mesenchymal Transition and Drug Resistance to Gefitinib by Targeting MAGI2 in Lung Adenocarcinoma Cells. Molecular Cancer Therapeutics 2013, 13(2):444-453.
    • (2013) Molecular Cancer Therapeutics , vol.13 , Issue.2 , pp. 444-453
    • Kitamura, K.1    Seike, M.2    Okano, T.3    Matsuda, K.4    Miyanaga, A.5    Mizutani, H.6    Noro, R.7    Minegishi, Y.8    Kubota, K.9    Gemma, A.10
  • 33
    • 84925287004 scopus 로고    scopus 로고
    • MiR-106b expression determines the proliferation paradox of TGF-beta in breast cancer cells
    • Gong C, Qu S, Liu B, Pan S, Jiao Y, Nie Y, Su F, Liu Q, Song E: MiR-106b expression determines the proliferation paradox of TGF-beta in breast cancer cells. Oncogene 2015, 34(1):84-93.
    • (2015) Oncogene , vol.34 , Issue.1 , pp. 84-93
    • Gong, C.1    Qu, S.2    Liu, B.3    Pan, S.4    Jiao, Y.5    Nie, Y.6    Su, F.7    Liu, Q.8    Song, E.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.