ORF8-related genetic evidence for Chinese horseshoe bats as the source of human severe acute respiratory syndrome coronavirus

Journal of Infectious Diseases

Volumn 213, Issue 4, 2016, Pages 579-583

  Wu, Zhiqiang ^a   Yang, Li ^a   Ren, Xianwen ^a   Zhang, Junpeng ^c   Yang, Fan ^a   Zhang, Shuyi ^d   Jin, Qi ^a,b  

^a INSTITUTE OF PATHOGEN BIOLOGY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c EAST CHINA NORMAL UNIVERSITY   (China)

^d SHENYANG AGRICULTURAL UNIVERSITY   (China)

Author keywords

bats; ORF8; origin; severe acute respiratory syndrome coronavirus

Indexed keywords

ORF6 PROTEIN; ORF7A PROTEIN; ORF7B PROTEIN; ORF8 PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; MATRIX PROTEIN; SARS7A PROTEIN, SARS VIRUS; VIRUS RNA;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; BAT; CHINA; CONTROLLED STUDY; HUMAN; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHYLOGENY; PRIORITY JOURNAL; RHINOLOPHUS FERRUMEQUINUM; RHINOLOPHUS SINICUS; SARS CORONAVIRUS; SEQUENCE ANALYSIS; ANIMAL; CLASSIFICATION; CLUSTER ANALYSIS; DNA SEQUENCE; GENETICS; GENOTYPE; MOLECULAR EVOLUTION; MOLECULAR GENETICS; SEQUENCE HOMOLOGY; VIROLOGY;

ANIMALS; CHINA; CHIROPTERA; CLUSTER ANALYSIS; EVOLUTION, MOLECULAR; GENOTYPE; HUMANS; MOLECULAR SEQUENCE DATA; RNA, VIRAL; SARS VIRUS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY; VIRAL MATRIX PROTEINS;

EID: 84957556827     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiv476     Document Type: Article

References (15)

1. Donnelly CA, Fisher MC, Fraser C, et al. Epidemiological and genetic analysis of severe acute respiratory syndrome. Lancet Infect Dis 2004; 4: 672-83
2. Ge XY, Li JL, Yang XL, et al. Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor. Nature 2013; 503: 535-8
3. Li W, Shi Z, Yu M, et al. Bats are natural reservoirs of SARS-like coronaviruses. Science 2005; 310: 676-9
4. Rota PA, Oberste MS, Monroe SS, et al. Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science 2003; 300: 1394-9
5. He B, Zhang Y, Xu L, et al. Identification of diverse alphacoronaviruses and genomic characterization of a novel severe acute respiratory syndrome-like coronavirus from bats in China. J Virol 2014; 88: 7070-82
6. Wu Z, Yang L, Ren X, et al. Deciphering the bat virome catalog to better understand the ecological diversity of bat viruses and the bat origin of emerging infectious diseases. ISME J 2015; doi: 10.1038/ismej.2015.138
7. Holmes KV, Enjuanes L. Virology. The SARS coronavirus: a postgenomic era. Science 2003; 300: 1377-8
8. Woo PC, Lau SK, Huang Y, Yuen KY. Coronavirus diversity, phylogeny and interspecies jumping. Exp Biol Med (Maywood) 2009; 234: 1117-27
9. Molecular evolution of the SARS coronavirus during the course of the SARS epidemic in China. Science 2004; 303: 1666-9
10. Song HD, Tu CC, Zhang GW, et al. Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proc Natl Acad Sci U S A 2005; 102: 2430-5
11. Chen CY, Ping YH, Lee HC, et al. Open reading frame 8a of the human severe acute respiratory syndrome coronavirus not only promotes viral replication but also induces apoptosis. J Infect Dis 2007; 196: 405-15
12. Law PY, Liu YM, Geng H, Kwan KH, Waye MM, Ho YY. Expression and functional characterization of the putative protein 8b of the severe acute respiratory syndrome-Associated coronavirus. FEBS Lett 2006; 580: 3643-8
13. Keng CT, Choi YW, Welkers MR, et al. The human severe acute respiratory syndrome coronavirus (SARS-CoV) 8b protein is distinct from its counterpart in animal SARS-CoV and down-regulates the expression of the envelope protein in infected cells. Virology 2006; 354: 132-42
14. Lau SK, Feng Y, Chen H, et al. SARS coronavirus ORF8 protein is acquired from SARS-related coronavirus from greater horseshoe bats through recombination. J Virol 2015
15. Guan Y, Zheng BJ, He YQ, et al. Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China. Science 2003; 302: 276-8