Expression and functional characterization of the putative protein 8b of the severe acute respiratory syndrome-associated coronavirus

FEBS Letters

Volumn 580, Issue 15, 2006, Pages 3643-3648

  Law, Pui Ying Peggy ^a   Liu, Yuet Man ^a   Geng, Hua ^a   Kwan, Ka Ho ^a   Waye, Mary Miu Yee ^a   Ho, Yuan Yuan ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Coronavirus; SARS 8b; SARS ORF 8; Severe acute respiratory syndrome; X5

Indexed keywords

SARS 6 PROTEIN; SARS 8B PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; DNA SYNTHESIS; MAMMAL CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SARS CORONAVIRUS;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; CRICETINAE; DNA; GENE EXPRESSION; GENE EXPRESSION REGULATION, VIRAL; GENES, REPORTER; SARS VIRUS; THYMIDINE; VIRAL PROTEINS;

CORONAVIRUS; MAMMALIA; SARS CORONAVIRUS;

EID: 33745165197     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.05.051     Document Type: Article

References (26)

1. World Health Organization (WHO). www.who.int/csr/sars/en/.
2. Rota P.A., Oberste M.S., Monroe S.S., Nix W.A., Campagnoli R., Icenogle J.P., Penaranda S., Bankamp B., Maher K., Chen M.H., et al. Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science 300 (2003) 1394-1399
3. Marra M.A., Jones S.J.M., Astell C.R., et al. The genome sequence of the SARS-associated coronavirus. Science 300 (2003) 1399-1404
4. Alcami A., and Koszinowski J.H. Viral mechanisms of immune evasion. Immunol. Today 21 (2000) 445-447
5. de Haan C.A.M., Masters P.S., Shen X., Weiss S., and Rottier P.J.M. The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host. Virology 296 (2002) 177-189
6. Law P.T.W., Wong C.H., Au T.C.C., Chuck C.P., Kong S.K., Chan P.K., To K.F., Lo A.W.I., Chan J.Y.W., Suen Y.K., Chan H.Y., Fung K.P., Waye M.M.Y., Sung J.J.Y., Lo Y.M., and Tsui S.K.W. The 3a protein of severe acute respiratory syndrome-associated coronavirus induces apoptosis in Vero E6 cells. J. Gen. Virol. 86 (2005) 1921-1930
7. 1 arrest and apoptosis induced by SARS-CoV 3b protein in transfected cells. Virol. J. 2 (2005) 66
8. Tan Y.J., Burtram C.F., Goh P.Y., Shen S., Tan T.H.P., Lim S.G., and Hong W. Overexpression of 7a, a protein specifically encoded by the severe acute respiratory syndrome coronavirus, induces apoptosis via a caspase-dependent pathway. J. Virol. 78 (2005) 14043-14047
9. Nicholls J.M., Poon L.L.M., Lee K.C., et al. Lung pathology of fatal severe acute respiratory syndrome. Lancet 361 (2003) 1773-1778
10. Geng H., Liu Y.M., Chan W.S., Lo A.W.I., Au D.M.Y., Waye M.M.Y., and Ho Y.Y. The putative protein 6 of the severe acute respiratory syndrome-associated coronavirus: expression and functional characterization. FEBS Lett. 579 (2005) 6763-6768
11. Guan Y., Zheng B.J., and He Y.Q. Isolation and characterization of viruses related to the SARS coronavirus from animals in Southern China. Science 302 (2003) 276-278
12. Kan B., Wang M., Jing H., Xu H., Jiang X., Yan M., Liang W., Zheng H., Wan K., Liu Q., et al. Molecular evolution analysis and geographic investigation of severe acute respiratory syndrome coronavirus-like virus in palm civets at an animal market and on farms. J. Virol. 79 (2005) 11892-11900
13. Tsui S.K.W., Chim S.S.C., and Lo Y.M.D. Coronavirus genomic-sequence variations and the epidemiology of the severe acute respiratory syndrome. N. Engl. J. Med. 349 (2003) 187-188
14. Ito N., Mossel E.C., Narayanan K., Popov V.L., Huang Ch., Inoue T., Peters C.J., and Makino S. Severe acute respiratory syndrome coronavirus 3a protein is a viral structural protein. J. Virol. 79 (2005) 3182-3186
15. Yang S.Q., Walter M., and Standring D.N. Hepatitis B virus p25 precore protein accumulates in Xenopus oocytes as an untranslocated phosphoprotein with an uncleaved signal peptide. J. Virol. 66 (1992) 37-45
16. Gubin A.N., Reddy B., Njoroge J.M., and Miller J.L. Long-term, stable expression of green fluorescent protein in mammalian cells. Biochem. Biophys. Res. Commun. 236 (1997) 347-350
17. Degreve B., Johansson M., De Clercq E., Karlsson A., and Balzarini J. Differential intracellular compartmentalization of herpetic thymidine kinaeses (TKs) in TK gene-transfected tumor cells: molecular characterization of the nuclear localization signal of herpes simplex virus type 1 TK. J. Virol. 72 (1998) 9535-9543
18. Yamashita M., and Emerman M. Retroviral infection of non-dividing cells: old and new perspectives. Virology 344 (2006) 88-93
19. Weiss S.R., and Navas-Martin S. Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus. Microbiol. Mol. Biol. Rev. 69 (2005) 635-664
20. I expression increases cytoplasmic calcium to enhance the activation of nuclear factor of activated T cells. J. Virol. 76 (2002) 10374-10382
21. I enhances interleukin-2 production during T-cell activation. J. Virol. 20 (2003) 11027-11039
22. Albrecht B., and Lairmore M.D. Critical role of human T-lymphotrophic virus type 1 accessory proteins in viral replication and pathogenesis. MMBR 66 (2002) 396-406
23. II sensitizes Jurkat T cells to Ras-mediated apoptosis. J. Virol. 79 (2005) 9449-9457
24. II, a mitochondrial protein of human T cell leukemia virus type 1. Proc. Natl. Acad. Sci. USA 101 (2004) 6629-6634
25. Mahalingam S., Ayyavoo V., Patel M., Kieber-emmons T., and Weiner D.B. Nuclear import, virion incorporation, and cell cycle arrest/ differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr. J. Virol. 71 (1997) 6339-6347
26. Snijder E.J., Bredenbeek P.J., Dobbe J.C., Thiel V., Ziehuhr J., Poon L.L.M., Guan Y., Rozanov M., Spaan W.J.M., and Gorbalenya A.E. Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage. J. Mol. Biol. 331 (2003) 991-1004