Adaptive optics in multiphoton microscopy: Comparison of two, three and four photon fluorescence

Optics Express

Volumn 23, Issue 24, 2015, Pages 31472-31483

  Sinefeld, David ^a   Paudel, Hari P ^b   Ouzounov, Dimitre G ^a   Bifano, Thomas G ^b   Xu, Chris ^a  

^a School of Operations Research and Industrial Engineering   (United States)

^b BOSTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROMAGNETIC PULSE; FLUORESCENCE; LIGHT MODULATORS; MEMS; NONLINEAR FEEDBACK; OPTICAL SYSTEMS; PHASE SHIFT; ULTRAFAST LASERS; ULTRASHORT PULSES;

ABERRATION CORRECTION; ADAPTIVE OPTICAL SYSTEMS; ADAPTIVE OPTICS SYSTEMS; MICRO ELECTROMECHANICAL SYSTEM (MEMS); MULTI-PHOTON MICROSCOPY; PHASE SHIFTING INTERFEROMETRY; PHASE SPATIAL LIGHT MODULATOR; SOLITON SELF-FREQUENCY SHIFT;

ADAPTIVE OPTICS;

COMPARATIVE STUDY; DEVICE FAILURE ANALYSIS; DEVICES; EQUIPMENT DESIGN; EVALUATION STUDY; FEEDBACK SYSTEM; FIBER OPTICS; IMAGE ENHANCEMENT; INTERFEROMETRY; LASER; LENS; MINIATURIZATION; MULTIPHOTON MICROSCOPY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; FEEDBACK; FIBER OPTIC TECHNOLOGY; IMAGE ENHANCEMENT; INTERFEROMETRY; LASERS; LENSES; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; MINIATURIZATION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 84957544626     PISSN: None     EISSN: 10944087     Source Type: Journal    
DOI: 10.1364/OE.23.031472     Document Type: Article

References (35)

1. W. Denk, J. H. Strickler, and W. W. Webb, "Two-photon laser scanning fluorescence microscopy," Science 248(4951), 73-76 (1990).
2. C. Xu, W. Zipfel, J. B. Shear, R. M. Williams, and W. W. Webb, "Multiphoton fluorescence excitation: new spectral windows for biological nonlinear microscopy," Proc. Natl. Acad. Sci. U.S.A. 93(20), 10763-10768 (1996).
3. 3 regenerative amplifier," Opt. Lett. 28(12), 1022-1024 (2003).
4. D. Kobat, M. E. Durst, N. Nishimura, A. W. Wong, C. B. Schaffer, and C. Xu, "Deep tissue multiphoton microscopy using longer wavelength excitation," Opt. Express 17(16), 13354-13364 (2009).
5. J. N. D. Kerr and W. Denk, "Imaging in vivo: watching the brain in action," Nat. Rev. Neurosci. 9(3), 195-205 (2008).
6. D. A. Dombeck, C. D. Harvey, L. Tian, L. L. Looger, and D. W. Tank, "Functional imaging of hippocampal place cells at cellular resolution during virtual navigation," Nat. Neurosci. 13(11), 1433-1440 (2010).
7. J. C. Jung, A. D. Mehta, E. Aksay, R. Stepnoski, and M. J. Schnitzer, "In vivo mammalian brain imaging using one-and two-photon fluorescence microendoscopy," J. Neurophysiol. 92(5), 3121-3133 (2004).
8. D. Kobat, N. G. Horton, and C. Xu, "In vivo two-photon microscopy to 1.6-mm depth in mouse cortex," J. Biomed. Opt. 16(10), 106014 (2011).
9. N. G. Horton, K. Wang, D. Kobat, C. G. Clark, F. W. Wise, C. B. Schaffer, and C. Xu, "In vivo three-photon microscopy of subcortical structures within an intact mouse brain," Nat. Photonics 7(3), 205-209 (2013).
10. D. Ouzounov, N. Horton, T. Wang, D. Feng, N. Nishimura, and C. Xu, "In vivo three-photon calcium imaging of brain activity from layer 6 neurons in mouse brain," in CLEO: 2014 Postdeadline Paper Digest, OSA Technical Digest (online) (Optical Society of America, 2014), paper STh4C.2.
11. R. K. Tyson, Principles of Adaptive Optics, 3rd ed. (CRC, 2010).
12. Editorial, "Nature photonics technology focus: adaptive optics," Nat. Photonics 5, 15-28 (2011).
13. M. J. Booth, "Adaptive optics in microscopy," Philos. Trans. A Math. Phys. Eng. Sci. 365(1861), 2829-2843 (2007).
14. I. M. Vellekoop and A. P. Mosk, "Focusing coherent light through opaque strongly scattering media," Opt. Lett. 32(16), 2309-2311 (2007).
15. I. M. Vellekoop, A. Lagendijk, and A. P. Mosk, "Exploiting disorder for perfect focusing," Nat. Photonics 4(5), 320-322 (2010).
16. O. Katz, E. Small, and Y. Silberberg, "Looking around corners and through thin turbid layers in real time with scattered incoherent light," Nat. Photonics 6(8), 549-553 (2012).
17. N. Ji, D. E. Milkie, and E. Betzig, "Adaptive optics via pupil segmentation for high-resolution imaging in biological tissues," Nat. Methods 7(2), 141-147 (2010).
18. C. Wang, R. Liu, D. E. Milkie, W. Sun, Z. Tan, A. Kerlin, T.-W. Chen, D. S. Kim, and N. Ji, "Multiplexed aberration measurement for deep tissue imaging in vivo," Nat. Methods 11(10), 1037-1040 (2014).
19. J. Tang, R. N. Germain, and M. Cui, "Superpenetration optical microscopy by iterative multiphoton adaptive compensation technique," Proc. Natl. Acad. Sci. U.S.A. 109(22), 8434-8439 (2012).
20. L. Kong and M. Cui, "In vivo neuroimaging through the highly scattering tissue via iterative multi-photon adaptive compensation technique," Opt. Express 23(5), 6145-6150 (2015).
21. O. Katz, E. Small, Y. Guan, and Y. Silberberg, "Noninvasive nonlinear focusing and imaging through strongly scattering turbid layers," Optica 1(3), 170-174 (2014).
22. K. Wang, N. G. Horton, K. Charan, and C. Xu, "Advanced fiber soliton sources for nonlinear deep tissue imaging in biophotonics," IEEE J. Sel. Top. Quantum Electron. 20, 6800311 (2014).
23. K. Wang and C. Xu, "Tunable high-energy soliton pulse generation from a large mode-area fiber and its application to third harmonic generation microscopy," Appl. Phys. Lett. 99(7), 071112 (2011).
24. T. A. Pologruto, B. L. Sabatini, and K. Svoboda, "ScanImage: flexible software for operating laser scanning microscopes," Biomed. Eng. Online 2(1), 13 (2003).
25. C. Stockbridge, Y. Lu, J. Moore, S. Hoffman, R. Paxman, K. Toussaint, and T. Bifano, "Focusing through dynamic scattering media," Opt. Express 20(14), 15086-15092 (2012).
26. F. Wang, "Utility transforms of optical fields employing deformable mirror," Opt. Lett. 36(22), 4383-4385 (2011).
27. H. P. Paudel, C. Stockbridge, J. Mertz, and T. Bifano, "Focusing polychromatic light through strongly scattering media," Opt. Express 21(14), 17299-17308 (2013).
28. H. Schreiber and J. Bruning, Optical Shop Testing (John Wiley and Sons, Inc., 2006).
29. C. Xu and W. W. Webb, Topics in Fluorescence Spectroscopy, vol. 5 (Springer, 1997).
30. L. C. Cheng, N. G. Horton, K. Wang, S. J. Chen, and C. Xu, "Measurements of multiphoton action cross sections for multiphoton microscopy," Biomed. Opt. Express 5(10), 3427-3433 (2014).
31. R. Noll, "Zernike polynomials and atmospheric turbulence," J. Opt. Soc. Am. 66(3), 207-211 (1976).
32. M. Born and E. Wolf, Principles of Optics, 7th ed. (Cambridge University Press, 1999).
33. J. C. Wyant and K. Creath, "Basic wavefront aberration theory for optical metrology," in Applied Optics and Optical Engineering, J. C. Wyant, and R. R. Shannon, eds. (Academic Press, 1992), pp. 2-53.
34. D. Burke, B. Patton, F. Huang, J. Bewersdorf, and M. J. Booth, "Adaptive optics correction of specimen-induced aberrations in single-molecule switching microscopy," Optica 2(2), 177-185 (2015).
35. M. J. Booth, D. Débarre, and A. Jesacher, "Adaptive optics for biomedical microscopy," Opt. Photonics News 23(1), 22-29 (2012).