Integration of electrophysiological recordings with single-cell RNA-seq data identifies neuronal subtypes

Nature Biotechnology

Volumn 34, Issue 2, 2016, Pages 175-183

  Fuzik, Janos ^a,b   Zeisel, Amit ^a   Mate, Zoltan ^c   Calvigioni, Daniela ^a,b   Yanagawa, Yuchio ^d   Szabo, Gabor ^c   Linnarsson, Sten ^a   Harkany, Tibor ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Medical University of Vienna   (Austria)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^d GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; ELECTROPHYSIOLOGY; RNA;

ELECTROPHYSIOLOGICAL RECORDINGS; MOLECULAR PHENOTYPES; PYRAMIDAL CELL; REVERSE TRANSCRIPTION; RNA-SEQ DATUM; SINGLE CELLS; TRANSCRIPTOME DATUM; WHOLE CELL PATCH CLAMP;

NEURONS;

CANNABINOID 1 RECEPTOR; CHOLECYSTOKININ; COMPLEMENTARY DNA; GAMMA SYNUCLEIN; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE 67; NEUROPEPTIDE; NEUROTRANSMITTER RECEPTOR; SEROTONIN RECEPTOR; SYNAPTOBREVIN; SYNAPTOBREVIN 4; SYNAPTOTAGMIN; SYNAPTOTAGMIN 7; TRANSCRIPTOME; UNCLASSIFIED DRUG; VESICULAR GLUTAMATE TRANSPORTER 1; VESICULAR INHIBITORY AMINO ACID TRANSPORTER; VOLTAGE GATED CHLORIDE CHANNEL; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN ELECTROPHYSIOLOGY; CLINICAL ASSESSMENT; CLINICAL PROTOCOL; CONTROLLED STUDY; EX VIVO STUDY; GENE EXPRESSION; INTERNEURON; MOLECULAR LIBRARY; MOUSE; NEUROPHYSIOLOGY; NONHUMAN; PIPETTE; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; REVERSE TRANSCRIPTION; RNA SEQUENCE; SINGLE CELL ANALYSIS; SOMATOSENSORY CORTEX; WHOLE CELL PATCH CLAMP; ANIMAL; CYTOLOGY; ELECTROPHYSIOLOGY; GENE EXPRESSION PROFILING; METABOLISM; NERVE CELL; PATCH CLAMP TECHNIQUE; PROCEDURES; SEQUENCE ANALYSIS;

ANIMALS; ELECTROPHYSIOLOGY; GENE EXPRESSION PROFILING; MICE; NEURONS; PATCH-CLAMP TECHNIQUES; RNA, MESSENGER; SEQUENCE ANALYSIS, RNA; SINGLE-CELL ANALYSIS;

EID: 84957536197     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.3443     Document Type: Article

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