Increased Oxidative DNA Damage in Placenta Contributes to Cadmium-Induced Preeclamptic Conditions in Rat

Biological Trace Element Research

Volumn 170, Issue 1, 2016, Pages 119-127

  Zhang, Xiaojie ^a   Xu, Zhangye ^b   Lin, Feng ^a   Wang, Fan ^b   Ye, Duyun ^c   Huang, Yinping ^a  

^a THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL AND YUYING CHILDREN S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Cadmium chloride; DNA repair; Hypertension; Oxidative stress; Preeclampsia

Indexed keywords

CADMIUM CHLORIDE; NITRITE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; BLOOD PRESSURE MONITORING; BODY WEIGHT; CADMIUM BLOOD LEVEL; CHEMICAL PARAMETERS; CONTROLLED STUDY; DISEASE MODEL; DNA DAMAGE; DNA METABOLISM; DNA REPAIR; FEMALE; GESTATION PERIOD; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; KIDNEY PARENCHYMA; MOLECULAR PATHOLOGY; NONHUMAN; PLACENTA DISORDER; PLACENTA TISSUE; PREECLAMPSIA; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYSTOLIC BLOOD PRESSURE; TISSUE STRUCTURE; WESTERN BLOTTING; ANIMAL; CHEMICALLY INDUCED; METABOLISM; OXIDATIVE STRESS; PLACENTA; PREGNANCY; SPRAGUE DAWLEY RAT;

ANIMALS; CADMIUM CHLORIDE; DNA DAMAGE; FEMALE; OXIDATIVE STRESS; PLACENTA; PRE-ECLAMPSIA; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84957438751     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-015-0438-9     Document Type: Article

References (27)

1. Young BC, Levine RJ, Karumanchi SA (2010) Pathogenesis of preeclampsia. Annu Rev Pathol 5:173–192
2. Roberts JM, Cooper DW (2001) Pathogenesis and genetics of pre-eclampsia. Lancet 357:53–56
3. Lucian B, Camelia B, Vasile B, Otilia M, Mariana M (2010) Report on the influence of heavy metals on the evolution of the pregnancy in smoking mothers. Analele Universitătii din Oradea Fascicula: Ecotoxicologie, Zootehnie si Tehnologii de Industrie Alimentară 99–104.
4. Helmestam M, Stavreus-Evers A, Olovsson M (2010) Cadmium chloride alters mRNA levels of angiogenesis related genes in primary human endometrial endothelial cells grown in vitro. Reprod Toxicol 30:370–376
5. Ling Y, Ye X, Ji H, Zhang YH, Lai YS, et al (2010) Synthesis and evaluation of nitric oxide-releasing derivatives of farnesylthiosalicylic acid as anti-tumor agents. Bioorg Med Chem 18:3448–3456
6. -△△Ct method. Methods 25:402–408
7. Pistarini C (2013) Oxidative stress in post-acute ischemic stroke patients: relevance of early intensive neurorehabilitation. J Neurol Neurophysiol 4:154
8. Bartosz G (2003) Total antioxidant capacity. Adv Clin Chem 37:220–292
9. Mitra E, Ghosh AK, Ghosh D, Mukherjee D, Chattopadhyay A, Dutta S, et al (2012) Protective effect of aqueous curry leaf (Murraya koenigii) extract against cadmium-induced oxidative stress in rat heart. Food Chem Toxicol 50:1340–1353
10. Nair A, DeGheselle O, Smeets K, Van Kerkhove E, Cuypers A (2013) Cadmium-induced pathologies: where is the oxidative balance lost (or not)? Int J Mol Sci 14:6116–6143
11. Wang Q, Ning X, Chen L, Pei D, Zhao J, Zhang L, et al (2011) Responses of thioredoxin 1 and thioredoxin-related protein 14 mRNAs to cadmium and copper stresses in venerupis philippinarum. Comp Biochem Physiol C Toxicol Pharmacol 154:154–160
12. Zhang M, An C, Gao Y, Leak RK, Chen J, Zhang F (2013) Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection. Prog Neurobiol 100:30–47
13. Mann GE, Niehueser-Saran J, Watson A, Gao L, Ishii T, de Winter P, et al (2007) Nrf2/ARE regulated antioxidant gene expression in endothelial and smooth muscle cells in oxidative stress: implications for atherosclerosis and preeclampsia. Sheng Li Xue Bao 59:117–127
14. Lin F, Yu X, Zhang X, Guo Y, Huang Y, Zhou J, et al (2013) A synthetic analog of lipoxin A4 partially alleviates dexamethasone-induced fetal growth restriction in rats. Placenta 34:941–948
15. Storr SJ, Woolston CM, Zhang Y, Martin SG (2013) Redox environment, free radical, and oxidative DNA damage. Antioxid Redox Signal 18:2399–2408
16. Kasai H (1997) Analysis of a form of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis. Mutat Res Rev Mutat Res 387:147–163
17. Kelley MR, Georgiadis MM, Fishel ML (2012) APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1. Curr Mol Pharmacol 5:36–53
18. Ho E, Ames BN (2002) Low intracellular zinc induces oxidative DNA damage, disrupts p53, NF κB, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line. Proc Natl Acad Sci U S A 99:16770–16775
19. Hossain MZ, Gilbert SF, Patel K, Ghosh S, Bhunia AK, Kern SE (2013) Biological clues to potent DNA-damaging activities in food and flavoring. Food Chem Toxicol 55:557–567
20. Burton GJ, Jauniaux E (2011) Oxidative stress. Best Pract Res Clin Obstet Gynaecol 25:287–299
21. Cuypers A, Plusquin M, Remans T, Jozefczak M, Keunen E, Gielen H, et al (2010) Cadmium stress: an oxidative challenge. Biometals 23:927–940
22. Dai B, Liu T, Zhang B, Zhang X, Wang Z (2013) The polymorphism for endothelial nitric oxide synthase gene, the level of nitric oxide and the risk for pre-eclampsia: a meta-analysis. Gene 519:187–193
23. Palmer R, Bridge L, Foxwell N, Moncada S (1992) The role of nitric oxide in endothelial cell damage and its inhibition by glucocorticoids. Br J Pharmacol 105:11–12
24. Siddiqui IA, Jaleel A, Tamimi W, Al Kadri HM (2010) Role of oxidative stress in the pathogenesis of preeclampsia. Arch Gynecol Obstet 282:469–474
25. Ferramola ML, Antón RI, Anzulovich AC, Giménez MS (2011) Myocardial oxidative stress following sub-chronic and chronic oral cadmium exposure in rats. Environ Toxicol Pharmacol 32:17–26
26. Gonenc A, Hacisevki A, Tavil Y, Cengel A, Torun M (2013) Oxidative stress in patients with essential hypertension: a comparison of dippers and non-dippers. Eur J Intern Med 24:139–144
27. Frosina G (2000) Overexpression of enzymes that repair endogenous damage to DNA. Eur J Biochem 267:2135–2149