Circulating matrix metalloproteinase patterns in association with aortic dilatation in bicuspid aortic valve patients with isolated severe aortic stenosis

Heart and Vessels

Volumn 31, Issue 2, 2016, Pages 189-197

  Wang, Yongshi ^a   Wu, Boting ^a   Dong, Lili ^a   Wang, Chunsheng ^a   Wang, Xiaolin ^a   Shu, Xianhong ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Aortic dilatation; Aortic stenosis; Bicuspid aortic valve; Matrix metalloproteinase

Indexed keywords

COLLAGENASE 3; GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; NEUTROPHIL COLLAGENASE; STROMELYSIN; STROMELYSIN 2; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 4; BIOLOGICAL MARKER; MMP2 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; TISSUE INHIBITOR OF METALLOPROTEINASE;

ADULT; AGE DISTRIBUTION; AGED; AORTA DISEASE; AORTA STENOSIS; AORTIC DILATATION; ARTICLE; BICUSPID AORTIC VALVE; BODY SURFACE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HEART LEFT VENTRICLE MASS; HEART VENTRICLE HYPERTROPHY; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; SHEAR STRESS; ABNORMALITIES; AORTA VALVE; AORTIC ANEURYSM; AORTIC VALVE STENOSIS; AORTOGRAPHY; BLOOD; CHI SQUARE DISTRIBUTION; COMPLICATION; DOPPLER ECHOCARDIOGRAPHY; EARLY DIAGNOSIS; HEART VALVE DISEASES; LESIONS AND DEFECTS; MIDDLE AGED; MULTIDETECTOR COMPUTED TOMOGRAPHY; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE; PROCEDURES; RISK FACTOR; SEVERITY OF ILLNESS INDEX; STATISTICAL MODEL;

ADULT; AGED; AORTIC ANEURYSM; AORTIC VALVE; AORTIC VALVE STENOSIS; AORTOGRAPHY; BIOMARKERS; CHI-SQUARE DISTRIBUTION; DILATATION, PATHOLOGIC; EARLY DIAGNOSIS; ECHOCARDIOGRAPHY, DOPPLER; FEMALE; HEART VALVE DISEASES; HUMANS; LINEAR MODELS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; MULTIDETECTOR COMPUTED TOMOGRAPHY; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE OF TESTS; RISK FACTORS; SEVERITY OF ILLNESS INDEX; TISSUE INHIBITOR OF METALLOPROTEINASES;

EID: 84957434955     PISSN: 09108327     EISSN: 16152573     Source Type: Journal    
DOI: 10.1007/s00380-014-0593-5     Document Type: Article

References (39)

1. Verma S, Siu SC (2014) Aortic dilatation in patients with bicuspid aortic valve. N Engl J Med 370:1920–1929
2. Mahadevia R, Barker AJ, Schnell S, Entezari P, Kansal P, Fedak PW, Malaisrie SC, McCarthy P, Collins J, Carr J, Markl M (2014) Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy. Circulation 129:673–682
3. Tadros TM, Klein MD, Shapira OM (2009) Ascending aortic dilatation associated with bicuspid aortic valve: pathophysiology, molecular biology, and clinical implications. Circulation 119:880–890
4. Wang Y, Wu B, Dong L, Wang C, Shu X (2013) Type A aortic dissection in patients with bicuspid or tricuspid aortic valves: a retrospective comparative study in 288 Chinese patients. Eur J Cardiothorac Surg 44:172–177
5. Sciacca S, Pilato M, Mazzoccoli G, Pazienza V, Vinciguerra M (2013) Anti-correlation between longevity gene SirT1 and Notch signaling in ascending aorta biopsies from patients with bicuspid aortic valve disease. Heart Vessel 28:268–275
6. Davies RR, Kaple RK, Mandapati D, Gallo A, Botta DM Jr, Elefteriades JA, Coady MA (2007) Natural history of ascending aortic aneurysms in the setting of an unreplaced bicuspid aortic valve. Ann Thorac Surg 83:1338–1344
7. Nathan DP, Xu C, Plappert T, Desjardins B, Gorman JH 3rd, Bavaria JE, Gorman RC, Chandran KB, Jackson BM (2011) Increased ascending aortic wall stress in patients with bicuspid aortic valves. Ann Thorac Surg 92:1384–1389
8. Meierhofer C, Schneider EP, Lyko C, Hutter A, Martinoff S, Markl M, Hager A, Hess J, Stern H, Fratz S (2013) Wall shear stress and flow patterns in the ascending aorta in patients with bicuspid aortic valves differ significantly from tricuspid aortic valves: a prospective study. Eur Heart J Cardiovasc Imaging 14:797–804
9. Klein T, Bischoff R (2011) Physiology and pathophysiology of matrix metalloproteases. Amino Acids 41:271–290
10. Kaunas R, Kang H, Bayless KJ (2011) Synergistic regulation of angiogenic sprouting by biochemical factors and wall shear stress. Cell Mol Bioeng 4:547–559
11. Tzemos N, Lyseggen E, Silversides C, Jamorski M, Tong JH, Harvey P, Floras J, Siu S (2010) Endothelial function, carotid-femoral stiffness, and plasma matrix metalloproteinase-2 in men with bicuspid aortic valve and dilated aorta. J Am Coll Cardiol 55:660–668
12. Barker AJ, Markl M, Bürk J, Lorenz R, Bock J, Bauer S, Schulz-Menger J, von Knobelsdorff-Brenkenhoff F (2012) Bicuspid aortic valve is associated with altered wall shear stress in the ascending aorta. Circ Cardiovasc Imaging 5:457–466
13. Nishimura RA, Otto CM, Bonow RO, Carabello BA, Erwin JP 3rd, Guyton RA, O’Gara PT, Ruiz CE, Skubas NJ, Sorajja P, Sundt TM 3rd, Thomas JD (2014) 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 63:e57–e185
14. Hiratzka LF, Bakris GL, Beckman JA, Bersin RM, Carr VF, Casey DE Jr, Eagle KA, Hermann LK, Isselbacher EM, Kazerooni EA, Kouchoukos NT, Lytle BW, Milewicz DM, Reich DL, Sen S, Shinn JA, Svensson LG, Williams DM, American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology; American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, Society for Vascular Medicine (2010) 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with Thoracic Aortic Disease. J Am Coll Cardiol 55:e27–e129
15. Erbel R, Alfonso F, Boileau C, Dirsch O, Eber B, Haverich A, Rakowski H, Struyven J, Radegran K, Sechtem U, Taylor J, Zollikofer C, Klein WW, Mulder B, Providencia LA, Task Force on Aortic Dissection, European Society of Cardiology (2001) Diagnosis and management of aortic dissection. Eur Heart J 22:1642–1681
16. Baumgartner H, Hung J, Bermejo J, Chambers JB, Evangelista A, Griffin BP, Iung B, Otto CM, Pellikka PA, Quiñones M, American Society of Echocardiography, European Association of Echocardiography (2009) Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice. J Am Soc Echocardiogr 22:1–23
17. Vincentelli A, Susen S, Le Tourneau T, Six I, Fabre O, Juthier F, Bauters A, Decoene C, Goudemand J, Prat A, Jude B (2003) Acquired von Willebrand syndrome in aortic stenosis. N Engl J Med 349:343–349
18. Guntheroth WG (2008) A critical review of the American College of Cardiology/American Heart Association practice guidelines on bicuspid aortic valve with dilated ascending aorta. Am J Cardiol 102:107–110
19. van der Bom T, Zomer AC, Zwinderman AH, Meijboom FJ, Bouma BJ, Mulder BJ (2011) The changing epidemiology of congenital heart disease. Nat Rev Cardiol 8:50–60
20. Bissell MM, Hess AT, Biasiolli L, Glaze SJ, Loudon M, Pitcher A, Davis A, Prendergast B, Markl M, Barker AJ, Neubauer S, Myerson SG (2013) Aortic dilation in bicuspid aortic valve disease: flow pattern is a major contributor and differs with valve fusion type. Circ Cardiovasc Imaging 6:499–507
21. Walther T, Schubert A, Falk V, Binner C, Kanev A, Bleiziffer S, Walther C, Doll N, Autschbach R, Mohr FW (2001) Regression of left ventricular hypertrophy after surgical therapy for aortic stenosis is associated with changes in extracellular matrix gene expression. Circulation 104:I54–I58
22. Fujiwara T, Matsunaga T, Kameda K, Abe N, Ono H, Higuma T, Yokoyama J, Hanada H, Osanai T, Okumura K (2007) Nicorandil suppresses the increases in plasma level of matrix metalloproteinase activity and attenuates left ventricular remodeling in patients with acute myocardial infarction. Heart Vessel 22:303–309
23. Arjunon S, Rathan S, Jo H, Yoganathan AP (2013) Aortic valve: mechanical environment and mechanobiology. Ann Biomed Eng 41:1331–1346
24. Ikonomidis JS, Jones JA, Barbour JR, Stroud RE, Clark LL, Kaplan BS, Zeeshan A, Bavaria JE, Gorman JH 3rd, Spinale FG, Gorman RC (2007) Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with bicuspid or tricuspid aortic valves. J Thorac Cardiovasc Surg 133:1028–1036
25. Phillippi JA, Green BR, Eskay MA, Kotlarczyk MP, Hill MR, Robertson AM, Watkins SC, Vorp DA, Gleason TG (2014) Mechanism of aortic medial matrix remodeling is distinct in patients with bicuspid aortic valve. J Thorac Cardiovasc Surg 147:1056–1064
26. Gambillara V, Montorzi G, Haziza-Pigeon C, Stergiopulos N, Silacci P (2005) Arterial wall response to ex vivo exposure to oscillatory shear stress. J Vasc Res 42:535–544
27. Platt MO, Xing Y, Jo H, Yoganathan AP (2006) Cyclic pressure and shear stress regulate matrix metalloproteinases and cathepsin activity in porcine aortic valves. J Heart Valve Dis 15:622–629
28. Ikonomidis JS, Ivey CR, Wheeler JB, Akerman AW, Rice A, Patel RK, Stroud RE, Shah AA, Hughes CG, Ferrari G, Mukherjee R, Jones JA (2013) Plasma biomarkers for distinguishing etiologic subtypes of thoracic aortic aneurysm disease. J Thorac Cardiovasc Surg 145:1326–1333
29. Sultan S, Gosling M, Nagase H, Powell JT (2004) Shear stress-induced shedding of soluble intercellular adhesion molecule-1 from saphenous vein endothelium. FEBS Lett 564:161–165
30. Milkiewicz M, Kelland C, Colgan S, Haas TL (2006) Nitric oxide and p38 MAP kinase mediate shear stress-dependent inhibition of MMP-2 production in microvascular endothelial cells. J Cell Physiol 208:229–237
31. Yamane T, Mitsumata M, Yamaguchi N, Nakazawa T, Mochizuki K, Kondo T, Kawasaki T, Murata S, Yoshida Y, Katoh R (2010) Laminar high shear stress up-regulates type IV collagen synthesis and down-regulates MMP-2 secretion in endothelium. A quantitative analysis. Cell Tissue Res 340:471–479
32. Kilickesmez KO, Abaci O, Kocas C, Yildiz A, Kaya A, Okcun B, Kucukoglu S (2012) Dilatation of the ascending aorta and serum alpha 1-antitrypsin level in patients with bicuspid aortic valve. Heart Vessel 27:391–397
33. Carmona-Rivera C, Zhao W, Yalavarthi S, Kaplan MJ (2014) Neutrophil extracellular traps induce endothelial dysfunction in systemic lupus erythematosus through the activation of matrix metalloproteinase-2. Ann Rheum Dis. doi:10.1136/annrheumdis-2013-204837
34. Takata M, Amiya E, Watanabe M, Ozeki A, Watanabe A, Kawarasaki S, Nakao T, Hosoya Y, Uno K, Saito A, Murasawa T, Ono M, Nagai R, Komuro I (2014) Brachial artery diameter has a predictive value in the improvement of flow-mediated dilation after aortic valve replacement for aortic stenosis. Heart Vessel. doi:10.1007/s00380-014-0475-x
35. Wang Z, Juttermann R, Soloway PD (2000) TIMP-2 is required for efficient activation of proMMP-2 in vivo. J Biol Chem 275:26411–26415
36. Deryugina EI, Ratnikov B, Monosov E, Postnova TI, DiScipio R, Smith JW, Strongin AY (2001) MT1-MMP initiates activation of pro-MMP-2 and integrin alphavbeta3 promotes maturation of MMP-2 in breast carcinoma cells. Exp Cell Res 263:209–223
37. Mizia-Stec K, Lasota B, Mizia M, Chmiel A, Adamczyk T, Chudek J, Gasior Z (2013) Copeptin constitutes a novel biomarker of degenerative aortic stenosis. Heart Vessel 28:613–619
38. Spinale FG, Stolen CM (2013) Biomarkers and heart disease: what is translational success? J Cardiovasc Transl Res 6:447–448
39. Naito Y, Tsujino T, Lee-Kawabata M, Matsumoto M, Ezumi A, Nakao S, Goda A, Ohyanagi M, Masuyama T (2009) Matrix metalloproteinase-1 and -2 levels are differently regulated in acute exacerbation of heart failure in patients with and without left ventricular systolic dysfunction. Heart Vessel 24:181–186