Altered executive control network resting-state connectivity in social anxiety disorder

World Journal of Biological Psychiatry

Volumn 17, Issue 1, 2016, Pages 47-57

  Geiger, Maximilian J ^a   Domschke, Katharina ^a   Ipser, Jonathan ^b   Hattingh, Coenie ^b   Baldwin, David S ^b,c   Lochner, Christine ^d   Stein, Dan J ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^d STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

amygdala; attention; fMRI; prefrontal cortex; social phobia

Indexed keywords

ADULT; AMYGDALOID NUCLEUS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EXECUTIVE FUNCTION; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HUMAN; INDEPENDENT COMPONENT ANALYSIS; LIMBIC SYSTEM; MALE; MIDDLE FRONTAL GYRUS; ORBITAL CORTEX; RESTING STATE NETWORK; SOCIAL PHOBIA; AMYGDALA; ANXIETY DISORDER; ATTENTION; BRAIN MAPPING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PREFRONTAL CORTEX; STATISTICAL MODEL; YOUNG ADULT;

ADULT; AMYGDALA; ANXIETY DISORDERS; ATTENTION; BRAIN MAPPING; EXECUTIVE FUNCTION; FEMALE; HUMANS; LINEAR MODELS; MAGNETIC RESONANCE IMAGING; MALE; PREFRONTAL CORTEX; YOUNG ADULT;

EID: 84957109207     PISSN: 15622975     EISSN: 18141412     Source Type: Journal    
DOI: 10.3109/15622975.2015.1083613     Document Type: Article

References (65)

1. Allen EA, Erhardt EB, Damaraju E, Gruner W, Segall JM, Silva RF, et al. 2011. A baseline for the multivariate comparison of resting-state networks. Front Syst Neurosci 5:2
2. APA. 2000. DSM-IV-TR: diagnostic and statistical manual of mental disorders, text revision. Arlington, VA: American Psychiatric Association.
3. APA. 2013. Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Arlington, VA: American Psychiatric Publishing
4. Arnold AS, Triantafyllou C, Sawyer AT, Hofmann SG, Gabrieli JD, Whitfield-Gabrieli S. 2014. Hyper-connectivity of subcortical resting-state networks in social anxiety disorder. Brain Connect 4:81-90
5. Basten U, Stelzel C, Fiebach CJ. 2011. Trait anxiety modulates the neural efficiency of inhibitory control. J Cogn Neurosci 23:3132-3145
6. Baur V, Bruhl AB, Herwig U, Eberle T, Rufer M, Delsignore A, et al. 2013. Evidence of frontotemporal structural hypoconnectivity in social anxiety disorder: A quantitative fiber tractography study. Hum Brain Mapp 34:437-446
7. Beckmann CF, DeLuca M, Devlin JT, Smith SM. 2005. Investigations into resting-state connectivity using independent component analysis. Philos Trans R Soc Lond, B Biol Sci 360:1001-1013
8. Birbaumer N, Grodd W, Diedrich O, Klose U, Erb M, Lotze M, et al. 1998. fMRI reveals amygdala activation to human faces in social phobics. Neuroreport 9:1223-1226
9. Bishop SJ. 2007. Neurocognitive mechanisms of anxiety: an integrative account. Trends Cogn Sci (Regul. Ed.) Sci 11:307-316
10. Bishop SJ. 2009. Trait anxiety and impoverished prefrontal control of attention. Nat Neurosci 12:92-98
11. Biswal BB, Mennes M, Zuo XN, Gohel S, Kelly C, Smith SM, et al. 2010. Toward discovery science of human brain function. Proc Natl Acad Sci USA 107:4734-4739
12. Blair K, Geraci M, Devido J, McCaffrey D, Chen G, Vythilingam M, et al. 2008. Neural response to self- and other referential praise and criticism in generalized social phobia. Arch Gen Psychiatry 65:1176-1184
13. Brett M, Anton JL, Valabregue R, Poline JB. 2002. Region of interest analysis using the MarsBar toolbox for SPM 99. Neuroimage 16:S497
14. Bruhl AB, Delsignore A, Komossa K, Weidt S. 2014. Neuroimaging in social anxiety disorder-A meta-analytic review resulting in a new neurofunctional model. Neurosci Biobehav Rev 47:260-280
15. Bruhl AB, Herwig U, Delsignore A, Jancke L, Rufer M. 2013. General emotion processing in social anxiety disorder: neural issues of cognitive control. Psychiatry Res 212:108-115
16. Bruhl AB, Rufer M, Delsignore A, Kaffenberger T, Jancke L, Herwig U. 2011. Neural correlates of altered general emotion processing in social anxiety disorder. Brain Res 1378:72-83
17. Calhoun VD, Adali T, Pearlson GD, Pekar JJ. 2001. Spatial and temporal independent component analysis of functional MRI data containing a pair of task-related waveforms. Hum Brain Mapp 13:43-53
18. Carmichael ST, Price JL. 1995. Limbic connections of the orbital and medial prefrontal cortex in macaque monkeys. J Comp Neurol 363:615-641
19. Catani M, Howard RJ, Pajevic S, Jones DK. 2002. Virtual in vivo interactive dissection of white matter fasciculi in the human brain. Neuroimage 17:77-94
20. Cole MW, Repovs G, Anticevic A. 2014. The frontoparietal control system: A central role in mental health. Neuroscientist 20:652-664
21. Corbetta M, Shulman GL. 2002. Control of goal-directed and stimulus-driven attention in the brain. Nat Rev Neurosci 3:201-215
22. Cox RW. 1996. AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Comput Biomed Res 29:162-173
23. Damoiseaux JS, Rombouts SA, Barkhof F, Scheltens P, Stam CJ, Smith SM, et al. 2006. Consistent resting-state networks across healthy subjects. Proc Natl Acad Sci USA 103:13848-13853
24. Danti S, Ricciardi E, Gentili C, Gobbini MI, Pietrini P, Guazzelli M. 2010. Is social phobia a "MisCommunication" disorder? Brain functional connectivity during face perception differs between patients with social phobia and healthy control subjects. Front Syst Neurosci 4:152
25. Ding J, Chen H, Qiu C, Liao W, Warwick JM, Duan X, et al. 2011. Disrupted functional connectivity in social anxiety disorder: a resting-state fMRI study. Magn Reson Imaging 29:701-711
26. Dodhia S, Hosanagar A, Fitzgerald DA, Labuschagne I, Wood AG, Nathan PJ, et al. 2014. Modulation of resting-state amygdala- frontal functional connectivity by oxytocin in generalized social anxiety disorder. Neuropsychopharmacology 39:2061-2069
27. Etkin A, Prater KE, Schatzberg AF, Menon V, Greicius MD. 2009. Disrupted amygdalar subregion functional connectivity and evidence of a compensatory network in generalized anxiety disorder. Arch Gen Psychiatry 66:1361-1372
28. Etkin A, Wager TD. 2007. Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. Am J Psychiatry 164:1476-1488
29. First MB, Spitzer RL, Gibbon M, Williams JBW, Benjamin L. 1998. Structured clinical interview for DSM-IV axis I disorders (SCID) version 2.0. New York, NY: Biometrics Research Department, New York State Psychiatric Institute
30. Fouche JP, van Der Wee NJ, Roelofs K, Stein DJ. 2013. Recent advances in the brain imaging of social anxiety disorder. Hum Psychopharmacol 28:102-105
31. Freitas-Ferrari MC, Hallak JE, Trzesniak C, Filho AS, Machado-de- Sousa JP, Chagas MH, et al. 2010. Neuroimaging in social anxiety disorder: a systematic review of the literature. Prog Neuropsychopharmacol Biol Psychiatry 34:565-580
32. Geiger MJ, Neufang S, Stein DJ, Domschke K. 2014. Arousal and the attentional network in panic disorder. Hum Psychopharmacol 29:599-603
33. Gentili C, Ricciardi E, Gobbini MI, Santarelli MF, Haxby JV, Pietrini P, et al. 2009. Beyond amygdala: Default Mode Network activity differs between patients with social phobia and healthy controls. Brain Res Bull 79:409-413
34. Gimenez M, Ortiz H, Soriano-Mas C, Lopez-Sola M, Farre M, Deus J, et al. 2014. Functional effects of chronic paroxetine versus placebo on the fear, stress and anxiety brain circuit in Social Anxiety Disorder: initial validation of an imaging protocol for drug discovery. Eur Neuropsychopharmacol 24:105-116
35. Hahn A, Stein P, Windischberger C, Weissenbacher A, Spindelegger C, Moser E, et al. 2011. Reduced resting-state functional connectivity between amygdala and orbitofrontal cortex in social anxiety disorder. Neuroimage 56:881-889
36. Hakamata Y, Lissek S, Bar-Haim Y, Britton JC, Fox NA, Leibenluft E, et al. 2010. Attention bias modification treatment: a meta-analysis toward the establishment of novel treatment for anxiety. Biol Psychiatry 68:982-990
37. Hattingh CJ, Ipser J, Tromp SA, Syal S, Lochner C, Brooks SJ, et al. 2012. Functional magnetic resonance imaging during emotion recognition in social anxiety disorder: an activation likelihood meta-analysis. Front Hum Neurosci 6:347
38. Joel SE, Caffo BS, van Zijl PC, Pekar JJ. 2011. On the relationship between seed-based and ICA-based measures of functional connectivity. Magn Reson Med 66:644-657
39. Leary MR, Meadows S. 1991. Predictors, elicitors, and concomitants of social blushing. Journal of Personality and Social Psychology 60:254
40. Liao W, Chen H, Feng Y, Mantini D, Gentili C, Pan Z, et al. 2010a. Selective aberrant functional connectivity of resting state networks in social anxiety disorder. Neuroimage 52:1549-1558
41. Liao W, Qiu C, Gentili C, Walter M, Pan Z, Ding J, et al. 2010b. Altered effective connectivity network of the amygdala in social anxiety disorder: a resting-state FMRI study. PLoS One 5:e15238
42. Liebowitz MR. 1987. Social phobia. Mod Probl Pharmacopsychiatry 22:141-173
43. Margulies DS, Bottger J, Long X, Lv Y, Kelly C, Schafer A, et al. 2010. Resting developments: a review of fMRI post-processing methodologies for spontaneous brain activity. Magma 23:289-307
44. Mazaika P, Whitfield-Gabrieli S, Reiss A, Glover G. 2007. Artifact repair for fMRI data from high motion clinical subjects. Paper presented at 13th Annual Meeting of the Organization for Human Brain Mapping; Chicago, IL
45. McCabe C, Mishor Z, Filippini N, Cowen PJ, Taylor MJ, Harmer CJ. 2011. SSRI administration reduces resting state functional connectivity in dorso-medial prefrontal cortex. Mol Psychiatry 16:592-594
46. Milad MR, Rauch SL. 2007. The role of the orbitofrontal cortex in anxiety disorders. Ann N Y Acad Sci 1121:546-561
47. Pannekoek JN, Veer IM, van Tol MJ, van der Werff SJ, Demenescu LR, Aleman A, et al. 2013. Resting-state functional connectivity abnormalities in limbic and salience networks in social anxiety disorder without comorbidity. Eur Neuropsychopharmacol 23:186-195
48. Patriat R, Molloy EK, Meier TB, Kirk GR, Nair VA, Meyerand ME, et al. 2013. The effect of resting condition on resting-state fMRI reliability and consistency: a comparison between resting with eyes open, closed, and fixated. Neuroimage 78:463-473
49. Pejic T, Hermann A, Vaitl D, Stark R. 2013. Social anxiety modulates amygdala activation during social conditioning. Soc Cogn Affect Neurosci 8:267-276
50. Phan KL, Orlichenko A, Boyd E, Angstadt M, Coccaro EF, Liberzon I, et al. 2009. Preliminary evidence of white matter abnormality in the uncinate fasciculus in generalized social anxiety disorder. Biol Psychiatry 66:691-694
51. Prater KE, Hosanagar A, Klumpp H, Angstadt M, Phan KL. 2013. Aberrant amygdala-frontal cortex connectivity during perception of fearful faces and at rest in generalized social anxiety disorder. Depress Anxiety 30:234-241
52. Qiu C, Liao W, Ding J, Feng Y, Zhu C, Nie X, et al. 2011. Regional homogeneity changes in social anxiety disorder: a restingstate fMRI study. Psychiatry Res 194:47-53
53. Schaefer A, Burmann I, Regenthal R, Arelin K, Barth C, Pampel A, et al. 2014. Serotonergic modulation of intrinsic functional connectivity. Curr Biol 24:2314-2318
54. Schwarz KA, Wieser MJ, Gerdes AB, Muhlberger A, Pauli P. 2013. Why are you looking like that? How the context influences evaluation and processing of human faces. Soc Cogn Affect Neurosci 8:438-445
55. Shirer WR, Ryali S, Rykhlevskaia E, Menon V, Greicius MD. 2012. Decoding subject-driven cognitive states with whole-brain connectivity patterns. Cereb Cortex 22:158-165
56. Sladky R, Hoflich A, Kublbock M, Kraus C, Baldinger P, Moser E, et al. 2013. Disrupted effective connectivity between the amygdala and orbitofrontal cortex in social anxiety disorder during emotion discrimination revealed by dynamic causal modeling for fMRI. Cereb Cortex 25:895-903
57. Smith SM, Fox PT, Miller KL, Glahn DC, Fox PM, Mackay CE, et al. 2009. Correspondence of the brain's functional architecture during activation and rest. Proc Natl Acad Sci USA 106:13040-13045
58. Stein DJ, Ruscio AM, Lee S, Petukhova M, Alonso J, Andrade LH, et al. 2010. Subtyping social anxiety disorder in developed and developing countries. Depress Anxiety 27:390-403
59. Stein MB, Goldin PR, Sareen J, Zorrilla LT, Brown GG. 2002. Increased amygdala activation to angry and contemptuous faces in generalized social phobia. Arch Gen Psychiatry 59:1027-1034
60. Stein MB, Stein DJ. 2008. Social anxiety disorder. Lancet 371:1115-1125
61. Sylvester CM, Corbetta M, Raichle ME, Rodebaugh TL, Schlaggar BL, Sheline YI, et al. 2012. Functional network dysfunction in anxiety and anxiety disorders. Trends Neurosci 35:527-535
62. Taylor PA, Saad ZS. 2013. FATCAT: (an efficient) Functional and Tractographic Connectivity Analysis Toolbox. Brain Connect 3:523-535
63. Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, et al. 2002. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage 15:273-289
64. Warwick JM, Carey P, Jordaan GP, Dupont P, Stein DJ. 2008. Resting brain perfusion in social anxiety disorder: a voxel-wise whole brain comparison with healthy control subjects. Prog Neuropsychopharmacol Biol Psychiatry 32:1251-1256
65. Whitfield-Gabrieli S, Nieto-Castanon A. 2012. Conn: a functional connectivity toolbox for correlated and anticorrelated brain networks. Brain Connect 2:125-141