TGF-β2 induces epithelial-mesenchymal transition in cultured human lens epithelial cells through activation of the PI3K/Akt/mTOR signaling pathway

Molecular Medicine Reports

Volumn 13, Issue 2, 2016, Pages 1105-1110

  Guo, Rui ^a,b   Meng, Qianli ^b   Guo, Haike ^b   Xiao, Lijia ^c   Yang, Xiaohong ^b   Cui, Ying ^b   Huang, Yu ^b  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^c SHENZHEN EYE HOSPITAL   (China)

Author keywords

Epithelial cells; Human lens; LY294002; Phosphatidylinositol 3 kinase protein kinase B mammalian target of rapamycin pathway; Transforming growth factor 2

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CONNEXIN 43; FIBRONECTIN; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TRANSFORMING GROWTH FACTOR BETA2; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CHROMONE DERIVATIVE; MORPHOLINE DERIVATIVE; TARGET OF RAPAMYCIN KINASE;

ARTICLE; CELL COUNTING; CELL CULTURE; CELL STIMULATION; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVATION; ENZYME ACTIVITY; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LENS EPITHELIUM CELL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CELL DEATH; CELL SHAPE; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; LENS; METABOLISM; PHOSPHORYLATION;

CELL DEATH; CELL SHAPE; CELLS, CULTURED; CHROMONES; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; LENS, CRYSTALLINE; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRANSFORMING GROWTH FACTOR BETA2;

EID: 84956934538     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4645     Document Type: Article

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