Preimplant normothermic liver perfusion of a suboptimal liver donated after circulatory death

American Journal of Transplantation

Volumn 16, Issue 1, 2016, Pages 353-357

  Watson, C J E ^a   Kosmoliaptsis, V ^a   Randle, L V ^a   Russell, N K ^a   Griffiths, W J H ^a   Davies, S ^a   Mergental, H ^b   Butler, A J ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b UNIVERSITY HOSPITALS BIRMINGHAM NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; BILIRUBIN; LACTIC ACID; UREA;

ADULT; ARTICLE; BILE DUCT DISEASE; BIOCHEMISTRY; CADAVER DONOR; CASE REPORT; CHOLANGIOGRAPHY; COMMON BILE DUCT; ERYTHROCYTE; HEART ARREST; HUMAN; HUMAN TISSUE; LIVER ASSIST DEVICE; LIVER GRAFT; LIVER PERFUSION; LIVER TRANSPLANTATION; MALE; MEAN ARTERIAL PRESSURE; MIDDLE AGED; NORMOTHERMIC MACHINE PERFUSION; OXYGEN SATURATION; PRIORITY JOURNAL; VASCULAR EQUIPMENT; DONOR; LIVER; ORGAN PRESERVATION; PERFUSION; PROCEDURES; PROGNOSIS; TRANSPLANTATION; VASCULARIZATION;

HEART ARREST; HUMANS; LIVER; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; ORGAN PRESERVATION; PERFUSION; PROGNOSIS; TISSUE AND ORGAN PROCUREMENT; TISSUE DONORS;

EID: 84956911785     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.13448     Document Type: Article

References (19)

1. NHS Blood and Transplant. Organ Donation and Transplantation Annual Activity Report 2013/14. NHS Blood and Transplant, 2014.
2. Imber CJ, St Peter SD, Lopez de Cenarruzabeitia I, et al., Advantages of normothermic perfusion over cold storage in liver preservation. Transplantation 2002; 73: 701-709.
3. Schon MR, Kollmar O, Wolf S, et al., Liver transplantation after organ preservation with normothermic extracorporeal perfusion. Ann Surg 2001; 233: 114-123.
4. Boehnert MU, Yeung JC, Bazerbachi F, et al., Normothermic acellular ex vivo liver perfusion reduces liver and bile duct injury of pig livers retrieved after cardiac death. Am J Transplant 2013; 13: 1441-1449.
5. Xu H, Berendsen T, Kim K, et al., Excorporeal normothermic machine perfusion resuscitates pig DCD livers with extended warm ischemia. J Surg Res 2012; 173: e83-e88.
6. Reddy SP, Bhattacharjya S, Maniakin N, et al., Preservation of porcine non-heart-beating donor livers by sequential cold storage and warm perfusion. Transplantation 2004; 77: 1328-1332.
7. Guarrera JV, Henry SD, Samstein B, et al., Hypothermic machine preservation facilitates successful transplantation of "orphan" extended criteria donor livers. Am J Transplant 2015; 15: 161-169.
8. Dutkowski P, Schlegel A, de Oliveira M, Mullhaupt B, Neff F, Clavien PA., HOPE for human liver grafts obtained from donors after cardiac death. J Hepatol 2014; 60: 765-772.
9. Butler AJ, Rees MA, Wight DG, et al., Successful extracorporeal porcine liver perfusion for 72 hr. Transplantation 2002; 73: 1212-1218.
10. Op den Dries S, Karimian N, Sutton ME, et al., Ex vivo normothermic machine perfusion and viability testing of discarded human donor livers. Am J Transplant 2013; 13: 1327-1335.
11. Feng S, Goodrich NP, Bragg-Gresham JL, et al., Characteristics associated with liver graft failure: the concept of a donor risk index. Am J Transplant 2006; 6: 783-790.
12. Wells A, Watson CJ, Jamieson NV, Bradley JA., Which time is it? A suggestion for unambiguous nomenclature in transplantation. Am J Transplant 2007; 7: 1315-1316.
13. Olthoff KM, Kulik L, Samstein B, et al., Validation of a current definition of early allograft dysfunction in liver transplant recipients and analysis of risk factors. Liver Transpl 2010; 16: 943-949.
14. Steen S, Ingemansson R, Eriksson L, et al., First human transplantation of a nonacceptable donor lung after reconditioning ex vivo. Ann Thorac Surg 2007; 83: 2191-2194.
15. Wierup P, Haraldsson A, Nilsson F, et al., Ex vivo evaluation of nonacceptable donor lungs. Ann Thorac Surg 2006; 81: 460-466.
16. Harper S, Hosgood S, Kay M, Nicholson M., Leucocyte depletion improves renal function during reperfusion using an experimental isolated haemoperfused organ preservation system. Br J Surg 2006; 93: 623-629.
17. Yates PJ, Hosgood SA, Nicholson ML., Leukocyte and platelet depletion improves blood flow and function in a renal transplant model. J Surg Res 2012; 172: 159-164.
18. Nicholson ML, Hosgood SA., Renal transplantation after ex vivo normothermic perfusion: The first clinical study. Am J Transplant 2013; 13: 1246-1252.
19. Jochmans I, Moers C, Smits JM, et al., The prognostic value of renal resistance during hypothermic machine perfusion of deceased donor kidneys. Am J Transplant 2011; 11: 2214-2220.