Computational approaches for evaluating the effect of sequence variations and the intrinsically disordered C-terminal region of the Helicobacter pylori CagA protein on the interaction with tyrosine kinase Src

Journal of Molecular Modeling

Volumn 20, Issue 8, 2014, Pages 1-8

  Delgado, Paula ^a   Peñaranda, Natalia ^a   Zamora, María Antonia ^a   del Pilar Delgado, María ^a   Bohorquez, Eliana ^a   Castro, Harold ^a   Barrios, Andrés Fernando González ^a   Jaramillo, Carlos ^a  

^a UNIVERSIDAD DE LOS ANDES   (Colombia)

Author keywords

CagA protein; CagA protein cellular partners; Helicobacter pylori; Molecular docking; Molecular dynamics simulations

Indexed keywords

CAGA PROTEIN; INTRINSICALLY DISORDERED PROTEIN; PROTEIN TYROSINE KINASE; PROTEIN VARIANT; TYROSINE PROTEIN KINASE SRC; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; CAGA PROTEIN, HELICOBACTER PYLORI; PROTEIN BINDING;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BIOINFORMATICS; CARBOXY TERMINAL SEQUENCE; HELICOBACTER PYLORI; MATHEMATICAL ANALYSIS; MOLECULAR DOCKING; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; STATIC ELECTRICITY; STATISTICAL MODEL; BIOLOGY; CHEMISTRY; HUMAN; METABOLISM; PROCEDURES; PROTEIN FOLDING; THERMODYNAMICS;

AMINO ACID SEQUENCE; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; COMPUTATIONAL BIOLOGY; HELICOBACTER PYLORI; HUMANS; MOLECULAR DOCKING SIMULATION; PROTEIN BINDING; PROTEIN FOLDING; SRC-FAMILY KINASES; THERMODYNAMICS;

EID: 84956898832     PISSN: 16102940     EISSN: 09485023     Source Type: Journal    
DOI: 10.1007/s00894-014-2406-2     Document Type: Article

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