Cationic Pillararenes Potently Inhibit Biofilm Formation without Affecting Bacterial Growth and Viability

Journal of the American Chemical Society

Volumn 138, Issue 3, 2016, Pages 754-757

  Joseph, Roymon ^a   Naugolny, Alissa ^a   Feldman, Mark ^a   Herzog, Ido M ^a   Fridman, Micha ^a   Cohen, Yoram ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; HEALTH RISKS; MEDICAL APPLICATIONS;

ANTI-MICROBIAL ACTIVITY; BACTERIAL GROWTH; BACTERIAL INFECTIONS; BIOFILM FORMATION; BIOFILM INHIBITIONS; GRAM-POSITIVE PATHOGENS; MEMBRANE DAMAGE; QUATERNARY AMMONIUM GROUP;

BIOFILMS;

AMPHOPHILE; ANTIINFECTIVE AGENT; BROMINE DERIVATIVE; CATION; COUNTERION; DECA TRIMETHYLAMMONIUM PILLAR[5]ARENE; HALOGEN; MACROCYCLIC COMPOUND; PILLARARENE; PILLAR[6]ARENE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; QUATERNARY AMMONIUM DERIVATIVE; TETRAMETHYLAMMONIUM BROMIDE; TETRAMETHYLAMMONIUM CHLORIDE; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIAL MEMBRANE; BACTERIAL STRAIN; BIOFILM; CELL CULTURE; CELL MEMBRANE; CELL VIABILITY; CHEMICAL INTERACTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; ERYTHROCYTE; ESCHERICHIA COLI; HUMAN; HUMAN CELL; HYDROPHOBICITY; MAMMAL CELL; MEMBRANE DAMAGE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PSEUDOMONAS AERUGINOSA; CELL LINE; CELL PROLIFERATION; CHEMISTRY; CONFORMATION; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; GRAM POSITIVE BACTERIUM; GROWTH, DEVELOPMENT AND AGING; MICROBIAL VIABILITY; STRUCTURE ACTIVITY RELATION;

ANTIMICROBIAL CATIONIC PEPTIDES; BIOFILMS; CATIONS; CELL LINE; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; GRAM-POSITIVE BACTERIA; HUMANS; MICROBIAL VIABILITY; MOLECULAR CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84956816827     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b11834     Document Type: Article

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