메뉴 건너뛰기




Volumn 16, Issue 1, 2016, Pages 71-78

A prospective randomized evaluation of a pharmacogenomic approach to antiplatelet therapy among patients with ST-elevation myocardial infarction: The RAPID STEMI study

Author keywords

[No Author keywords available]

Indexed keywords

CLOPIDOGREL; FIBRINOGEN RECEPTOR; PRASUGREL; ABCB1 PROTEIN, HUMAN; ANTITHROMBOCYTIC AGENT; CYP2C19 PROTEIN, HUMAN; CYTOCHROME P450 2C19; MULTIDRUG RESISTANCE PROTEIN; TICLOPIDINE;

EID: 84956762057     PISSN: 1470269X     EISSN: 14731150     Source Type: Journal    
DOI: 10.1038/tpj.2015.17     Document Type: Article
Times cited : (41)

References (50)
  • 1
    • 27644548513 scopus 로고    scopus 로고
    • Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: Randomised placebo-controlled trial
    • Chen ZM, Jiang LX, Chen YP, Xie JX, Pan HC, Peto R et al. Addition of clopidogrel to aspirin in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial. Lancet 2005; 366: 1607-1621.
    • (2005) Lancet , vol.366 , pp. 1607-1621
    • Chen, Z.M.1    Jiang, L.X.2    Chen, Y.P.3    Xie, J.X.4    Pan, H.C.5    Peto, R.6
  • 2
    • 24644495673 scopus 로고    scopus 로고
    • Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: The PCI-CLARITY study
    • Sabatine MS, Cannon CP, Gibson CM, Lopez-Sendon JL, Montalescot G, Theroux P et al. Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: the PCI-CLARITY study. JAMA 2005; 294: 1224-1232.
    • (2005) JAMA , vol.294 , pp. 1224-1232
    • Sabatine, M.S.1    Cannon, C.P.2    Gibson, C.M.3    Lopez-Sendon, J.L.4    Montalescot, G.5    Theroux, P.6
  • 3
    • 73449142798 scopus 로고    scopus 로고
    • 2009 Focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update): A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
    • Kushner FG, Hand M, Smith SC Jr, King SB III, Anderson JL, Antman EM et al. 2009 Focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2009; 120: 2271-2306.
    • (2009) Circulation , vol.120 , pp. 2271-2306
    • Kushner, F.G.1    Hand, M.2    Smith, S.C.3    King, S.B.4    Anderson, J.L.5    Antman, E.M.6
  • 4
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK et al. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001; 345: 494-502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5    Fox, K.K.6
  • 5
    • 0035908781 scopus 로고    scopus 로고
    • Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: The PCI-CURE study
    • Mehta SR, Yusuf S, Peters RJ, Bertrand ME, Lewis BS, Natarajan MK et al. Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study. Lancet 2001; 358: 527-533.
    • (2001) Lancet , vol.358 , pp. 527-533
    • Mehta, S.R.1    Yusuf, S.2    Peters, R.J.3    Bertrand, M.E.4    Lewis, B.S.5    Natarajan, M.K.6
  • 6
    • 77958005516 scopus 로고    scopus 로고
    • Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): A randomised factorial trial
    • Mehta SR, Tanguay JF, Eikelboom JW, Jolly SS, Joyner CD, Granger CB et al. Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial. Lancet 2010; 376: 14233-14243.
    • (2010) Lancet , vol.376 , pp. 14233-14243
    • Mehta, S.R.1    Tanguay, J.F.2    Eikelboom, J.W.3    Jolly, S.S.4    Joyner, C.D.5    Granger, C.B.6
  • 7
    • 34047096264 scopus 로고    scopus 로고
    • Variability in individual responsiveness to clopidogrel: Clinical implications, management, and future perspectives
    • Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, Alfonso F, Macaya C, Bass TA et al. Variability in individual responsiveness to clopidogrel: clinical implications, management, and future perspectives. J Am Coll Cardiol 2007; 49: 1505-1516.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1505-1516
    • Angiolillo, D.J.1    Fernandez-Ortiz, A.2    Bernardo, E.3    Alfonso, F.4    Macaya, C.5    Bass, T.A.6
  • 8
    • 44949173754 scopus 로고    scopus 로고
    • Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation
    • Price MJ, Endemann S, Gollapudi RR, Valencia R, Stinis CT, Levisay JP et al. Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation. Eur Heart J 2008; 29: 992-1000.
    • (2008) Eur Heart J , vol.29 , pp. 992-1000
    • Price, M.J.1    Endemann, S.2    Gollapudi, R.R.3    Valencia, R.4    Stinis, C.T.5    Levisay, J.P.6
  • 11
    • 84865334740 scopus 로고    scopus 로고
    • Overcoming obstacles in pharmacogenomic strategies for antiplatelet drugs: Are we RAPID enough?
    • So DY, Roberts JD. Overcoming obstacles in pharmacogenomic strategies for antiplatelet drugs: are we RAPID enough? Pharmacogenomics 2012; 13: 1105-1108.
    • (2012) Pharmacogenomics , vol.13 , pp. 1105-1108
    • So, D.Y.1    Roberts, J.D.2
  • 13
    • 78049326068 scopus 로고    scopus 로고
    • Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: A meta-analysis
    • Mega JL, Simon T, Collet JP, Anderson JL, Antman EM, Bliden K et al. Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis. JAMA 2010; 304: 1821-1830.
    • (2010) JAMA , vol.304 , pp. 1821-1830
    • Mega, J.L.1    Simon, T.2    Collet, J.P.3    Anderson, J.L.4    Antman, E.M.5    Bliden, K.6
  • 15
    • 18144440017 scopus 로고    scopus 로고
    • Genetic variations of S-mephenytoin 4′-hydroxylase (CYP2C19) in the Chinese population
    • Xie HG. Genetic variations of S-mephenytoin 4′-hydroxylase (CYP2C19) in the Chinese population. Life Sci 2000; 66: L175-L181.
    • (2000) Life Sci , vol.66 , pp. L175-L181
    • Xie, H.G.1
  • 16
    • 77958105401 scopus 로고    scopus 로고
    • Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: A pharmacogenetic analysis
    • Mega JL, Close SL, Wiviott SD, Shen L, Walker JR, Simon T et al. Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis. Lancet 2010; 376: 1312-1319.
    • (2010) Lancet , vol.376 , pp. 1312-1319
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3    Shen, L.4    Walker, J.R.5    Simon, T.6
  • 17
    • 80054919425 scopus 로고    scopus 로고
    • Clinical, angiographic, and genetic factors associated with early coronary stent thrombosis
    • Cayla G, Hulot JS, O'Connor SA, Pathak A, Scott SA, Gruel Y et al. Clinical, angiographic, and genetic factors associated with early coronary stent thrombosis. JAMA 2011; 306: 1765-1774.
    • (2011) JAMA , vol.306 , pp. 1765-1774
    • Cayla, G.1    Hulot, J.S.2    O'Connor, S.A.3    Pathak, A.4    Scott, S.A.5    Gruel, Y.6
  • 18
    • 76349098199 scopus 로고    scopus 로고
    • Cytochrome 2C19∗17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement
    • Sibbing D, Koch W, Gebhard D, Schuster T, Braun S, Stegherr J et al. Cytochrome 2C19∗17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement. Circulation 2010; 121: 512-518.
    • (2010) Circulation , vol.121 , pp. 512-518
    • Sibbing, D.1    Koch, W.2    Gebhard, D.3    Schuster, T.4    Braun, S.5    Stegherr, J.6
  • 19
    • 84860538806 scopus 로고    scopus 로고
    • Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): A prospective, randomised, proof-of-concept trial
    • Roberts JD, Wells GA, Le May MR, Labinaz M, Glover C, Froeschl M et al. Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial. Lancet 2012; 379: 1705-1711.
    • (2012) Lancet , vol.379 , pp. 1705-1711
    • Roberts, J.D.1    Wells, G.A.2    Le May, M.R.3    Labinaz, M.4    Glover, C.5    Froeschl, M.6
  • 20
    • 80052573217 scopus 로고    scopus 로고
    • Platelet reactivity and cardiovascular outcomes after percutaneous coronary intervention: A time-dependent analysis of the Gauging Responsiveness with a VerifyNow P2Y12 assay: Impact on Thrombosis and Safety (GRAVITAS) trial
    • Price MJ, Angiolillo DJ, Teirstein PS, Lillie E, Manoukian SV, Berger PB et al. Platelet reactivity and cardiovascular outcomes after percutaneous coronary intervention: a time-dependent analysis of the Gauging Responsiveness with a VerifyNow P2Y12 assay: Impact on Thrombosis and Safety (GRAVITAS) trial. Circulation 2011; 124: 1132-1137.
    • (2011) Circulation , vol.124 , pp. 1132-1137
    • Price, M.J.1    Angiolillo, D.J.2    Teirstein, P.S.3    Lillie, E.4    Manoukian, S.V.5    Berger, P.B.6
  • 21
    • 77953911457 scopus 로고    scopus 로고
    • Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate
    • Bonello L, Tantry US, Marcucci R, Blindt R, Angiolillo DJ, Becker R et al. Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate. J Am Coll Cardiol 2010; 56: 919-933.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 919-933
    • Bonello, L.1    Tantry, U.S.2    Marcucci, R.3    Blindt, R.4    Angiolillo, D.J.5    Becker, R.6
  • 22
    • 34247558672 scopus 로고    scopus 로고
    • Clinical end points in coronary stent trials: A case for standardized definitions
    • Cutlip DE, Windecker S, Mehran R, Boam A, Cohen DJ, van Es GA et al. Clinical end points in coronary stent trials: a case for standardized definitions. Circulation 2007; 115: 2344-2351.
    • (2007) Circulation , vol.115 , pp. 2344-2351
    • Cutlip, D.E.1    Windecker, S.2    Mehran, R.3    Boam, A.4    Cohen, D.J.5    Van Es, G.A.6
  • 23
    • 79952598836 scopus 로고    scopus 로고
    • Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: The GRAVITAS randomized trial
    • Price MJ, Berger PB, Teirstein PS, Tanguay JF, Angiolillo DJ, Spriggs D et al. Standard- vs high-dose clopidogrel based on platelet function testing after percutaneous coronary intervention: the GRAVITAS randomized trial. JAMA 2011; 305: 1097-1105.
    • (2011) JAMA , vol.305 , pp. 1097-1105
    • Price, M.J.1    Berger, P.B.2    Teirstein, P.S.3    Tanguay, J.F.4    Angiolillo, D.J.5    Spriggs, D.6
  • 25
    • 20144365645 scopus 로고    scopus 로고
    • Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia
    • Stanulla M, Schaeffeler E, Flohr T, Cario G, Schrauder A, Zimmermann M et al. Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia. JAMA 2005; 293: 1485-1489.
    • (2005) JAMA , vol.293 , pp. 1485-1489
    • Stanulla, M.1    Schaeffeler, E.2    Flohr, T.3    Cario, G.4    Schrauder, A.5    Zimmermann, M.6
  • 26
    • 77953896604 scopus 로고    scopus 로고
    • Cardiovascular risk in clopidogrel-treated patients according to cytochrome P450 2C19∗2 loss-of-function allele or proton pump inhibitor coadministration: A systematic meta-analysis
    • Hulot JS, Collet JP, Silvain J, Pena A, Bellemain-Appaix A, Barthelemy O et al. Cardiovascular risk in clopidogrel-treated patients according to cytochrome P450 2C19∗2 loss-of-function allele or proton pump inhibitor coadministration: a systematic meta-analysis. J Am Coll Cardiol 2010; 56: 134-143.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 134-143
    • Hulot, J.S.1    Collet, J.P.2    Silvain, J.3    Pena, A.4    Bellemain-Appaix, A.5    Barthelemy, O.6
  • 28
    • 84555195438 scopus 로고    scopus 로고
    • CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: A systematic review and meta-analysis
    • Holmes MV, Perel P, Shah T, Hingorani AD, Casas JP. CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis. JAMA 2011; 306: 2704-2714.
    • (2011) JAMA , vol.306 , pp. 2704-2714
    • Holmes, M.V.1    Perel, P.2    Shah, T.3    Hingorani, A.D.4    Casas, J.P.5
  • 29
    • 84859532994 scopus 로고    scopus 로고
    • CYP2C19 genotype and cardiovascular events
    • Mega JL, Topol EJ, Sabatine MS. CYP2C19 genotype and cardiovascular events. JAMA 2012; 307: 1482-1483.
    • (2012) JAMA , vol.307 , pp. 1482-1483
    • Mega, J.L.1    Topol, E.J.2    Sabatine, M.S.3
  • 30
    • 77958100874 scopus 로고    scopus 로고
    • Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: A genetic substudy of the PLATO trial
    • Wallentin L, James S, Storey RF, Armstrong M, Barratt BJ, Horrow J et al. Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial. Lancet 2010; 376: 1320-1328.
    • (2010) Lancet , vol.376 , pp. 1320-1328
    • Wallentin, L.1    James, S.2    Storey, R.F.3    Armstrong, M.4    Barratt, B.J.5    Horrow, J.6
  • 31
    • 84861494090 scopus 로고    scopus 로고
    • Influence of genetic polymorphisms on the effect of high- and standard-dose clopidogrel after percutaneous coronary intervention: The GIFT (Genotype Information and Functional Testing) study
    • Price MJ, Murray SS, Angiolillo DJ, Lillie E, Smith EN, Tisch RL et al. Influence of genetic polymorphisms on the effect of high- and standard-dose clopidogrel after percutaneous coronary intervention: the GIFT (Genotype Information and Functional Testing) study. J Am Coll Cardiol 2012; 59: 1928-1937.
    • (2012) J Am Coll Cardiol , vol.59 , pp. 1928-1937
    • Price, M.J.1    Murray, S.S.2    Angiolillo, D.J.3    Lillie, E.4    Smith, E.N.5    Tisch, R.L.6
  • 32
    • 64549133799 scopus 로고    scopus 로고
    • Evaluation of individualized clopidogrel therapy after drug-eluting stent implantation in patients with high residual platelet reactivity: Design and rationale of the GRAVITAS trial
    • Price MJ, Berger PB, Angiolillo DJ, Teirstein PS, Tanguay JF, Kandzari DE et al. Evaluation of individualized clopidogrel therapy after drug-eluting stent implantation in patients with high residual platelet reactivity: design and rationale of the GRAVITAS trial. Am Heart J 2009; 157: 818-824.
    • (2009) Am Heart J , vol.157 , pp. 818-824
    • Price, M.J.1    Berger, P.B.2    Angiolillo, D.J.3    Teirstein, P.S.4    Tanguay, J.F.5    Kandzari, D.E.6
  • 33
    • 84861857758 scopus 로고    scopus 로고
    • A randomized trial of prasugrel versus clopidogrel in patients with high platelet reactivity on clopidogrel after elective percutaneous coronary intervention with implantation of drug-eluting stents: Results of the TRIGGER-PCI (Testing Platelet Reactivity In Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy With Prasugrel) study
    • Trenk D, Stone GW, Gawaz M, Kastrati A, Angiolillo DJ, Muller U et al. A randomized trial of prasugrel versus clopidogrel in patients with high platelet reactivity on clopidogrel after elective percutaneous coronary intervention with implantation of drug-eluting stents: results of the TRIGGER-PCI (Testing Platelet Reactivity In Patients Undergoing Elective Stent Placement on Clopidogrel to Guide Alternative Therapy With Prasugrel) study. J Am Coll Cardiol 2012; 59: 2159-2164.
    • (2012) J Am Coll Cardiol , vol.59 , pp. 2159-2164
    • Trenk, D.1    Stone, G.W.2    Gawaz, M.3    Kastrati, A.4    Angiolillo, D.J.5    Muller, U.6
  • 35
    • 60649112469 scopus 로고    scopus 로고
    • Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): Double-blind, randomised controlled trial
    • Montalescot G, Wiviott SD, Braunwald E, Murphy SA, Gibson CM, McCabe CH et al. Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trial. Lancet 2009; 373: 723-731.
    • (2009) Lancet , vol.373 , pp. 723-731
    • Montalescot, G.1    Wiviott, S.D.2    Braunwald, E.3    Murphy, S.A.4    Gibson, C.M.5    McCabe, C.H.6
  • 36
    • 78650174722 scopus 로고    scopus 로고
    • Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis
    • Steg PG, James S, Harrington RA, Ardissino D, Becker RC, Cannon CP et al. Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: a Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis. Circulation 2010; 122: 2131-2141.
    • (2010) Circulation , vol.122 , pp. 2131-2141
    • Steg, P.G.1    James, S.2    Harrington, R.A.3    Ardissino, D.4    Becker, R.C.5    Cannon, C.P.6
  • 37
    • 84882248344 scopus 로고    scopus 로고
    • Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): A prospective multicentre registry study
    • Stone GW, Witzenbichler B, Weisz G, Rinaldi MJ, Neumann FJ, Metzger DC et al. Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): a prospective multicentre registry study. Lancet 2013; 382: 614-623.
    • (2013) Lancet , vol.382 , pp. 614-623
    • Stone, G.W.1    Witzenbichler, B.2    Weisz, G.3    Rinaldi, M.J.4    Neumann, F.J.5    Metzger, D.C.6
  • 38
    • 84890025521 scopus 로고    scopus 로고
    • Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding
    • Tantry US, Bonello L, Aradi D, Price MJ, Jeong YH, Angiolillo DJ et al. Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding. J Am Coll Cardiol 2013; 62: 2261-2273.
    • (2013) J Am Coll Cardiol , vol.62 , pp. 2261-2273
    • Tantry, U.S.1    Bonello, L.2    Aradi, D.3    Price, M.J.4    Jeong, Y.H.5    Angiolillo, D.J.6
  • 39
    • 84872698656 scopus 로고    scopus 로고
    • 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
    • O'Gara PT, Kushner FG, Ascheim DD, Casey DE Jr, Chung MK, de Lemos JA et al. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2013; 61: e78-e140.
    • (2013) J Am Coll Cardiol , vol.61 , pp. e78-e140
    • O'Gara, P.T.1    Kushner, F.G.2    Ascheim, D.D.3    Casey, D.E.4    Chung, M.K.5    De Lemos, J.A.6
  • 40
    • 84866732231 scopus 로고    scopus 로고
    • ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation
    • Steg PG, James SK, Atar D, Badano LP, Blomstrom-Lundqvist C, Borger MA et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J 2012; 33: 2569-2619.
    • (2012) Eur Heart J , vol.33 , pp. 2569-2619
    • Steg, P.G.1    James, S.K.2    Atar, D.3    Badano, L.P.4    Blomstrom-Lundqvist, C.5    Borger, M.A.6
  • 41
    • 81855211733 scopus 로고    scopus 로고
    • Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease
    • Mega JL, Hochholzer W, Frelinger AL III, Kluk MJ, Angiolillo DJ, Kereiakes DJ et al. Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease. JAMA 2011; 306: 2221-2228.
    • (2011) JAMA , vol.306 , pp. 2221-2228
    • Mega, J.L.1    Hochholzer, W.2    Frelinger, A.L.3    Kluk, M.J.4    Angiolillo, D.J.5    Kereiakes, D.J.6
  • 42
    • 84868637235 scopus 로고    scopus 로고
    • Pharmacodynamic effect of switching therapy in patients with high on-treatment platelet reactivity and genotype variation with high clopidogrel dose versus prasugrel: The RESET GENE trial
    • Sardella G, Calcagno S, Mancone M, Palmirotta R, Lucisano L, Canali E et al. Pharmacodynamic effect of switching therapy in patients with high on-treatment platelet reactivity and genotype variation with high clopidogrel dose versus prasugrel: the RESET GENE trial. Circ Cardiovasc Interv 2012; 5: 698-704.
    • (2012) Circ Cardiovasc Interv , vol.5 , pp. 698-704
    • Sardella, G.1    Calcagno, S.2    Mancone, M.3    Palmirotta, R.4    Lucisano, L.5    Canali, E.6
  • 43
    • 84873284326 scopus 로고    scopus 로고
    • Decrease in high on-treatment platelet reactivity (HPR) prevalence on switching from clopidogrel to prasugrel: Insights from the switching anti-platelet (SWAP) study
    • Saucedo JF, Angiolillo DJ, DeRaad R, Frelinger AL III, Gurbel PA, Costigan TM et al. Decrease in high on-treatment platelet reactivity (HPR) prevalence on switching from clopidogrel to prasugrel: insights from the switching anti-platelet (SWAP) study. Thromb Haemost 2013; 109: 347-355.
    • (2013) Thromb Haemost , vol.109 , pp. 347-355
    • Saucedo, J.F.1    Angiolillo, D.J.2    DeRaad, R.3    Frelinger, A.L.4    Gurbel, P.A.5    Costigan, T.M.6
  • 44
    • 79960613122 scopus 로고    scopus 로고
    • Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy
    • Scott SA, Sangkuhl K, Gardner EE, Stein CM, Hulot JS, Johnson JA et al. Clinical Pharmacogenetics Implementation Consortium guidelines for cytochrome P450-2C19 (CYP2C19) genotype and clopidogrel therapy. Clin Pharmacol Ther 2011; 90: 328-332.
    • (2011) Clin Pharmacol Ther , vol.90 , pp. 328-332
    • Scott, S.A.1    Sangkuhl, K.2    Gardner, E.E.3    Stein, C.M.4    Hulot, J.S.5    Johnson, J.A.6
  • 46
    • 27644465874 scopus 로고    scopus 로고
    • Clopidogrel effect on platelet reactivity in patients with stent thrombosis: Results of the CREST Study
    • Gurbel PA, Bliden KP, Samara W, Yoho JA, Hayes K, Fissha MZ et al. Clopidogrel effect on platelet reactivity in patients with stent thrombosis: results of the CREST Study. J Am Coll Cardiol 2005; 46: 1827-1832.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1827-1832
    • Gurbel, P.A.1    Bliden, K.P.2    Samara, W.3    Yoho, J.A.4    Hayes, K.5    Fissha, M.Z.6
  • 47
    • 33750479499 scopus 로고    scopus 로고
    • Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement
    • Hochholzer W, Trenk D, Bestehorn HP, Fischer B, Valina CM, Ferenc M et al. Impact of the degree of peri-interventional platelet inhibition after loading with clopidogrel on early clinical outcome of elective coronary stent placement. J Am Coll Cardiol 2006; 48: 1742-1750.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1742-1750
    • Hochholzer, W.1    Trenk, D.2    Bestehorn, H.P.3    Fischer, B.4    Valina, C.M.5    Ferenc, M.6
  • 48
    • 8344221349 scopus 로고    scopus 로고
    • Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction
    • Matetzky S, Shenkman B, Guetta V, Shechter M, Bienart R, Goldenberg I et al. Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction. Circulation 2004; 109: 3171-3175.
    • (2004) Circulation , vol.109 , pp. 3171-3175
    • Matetzky, S.1    Shenkman, B.2    Guetta, V.3    Shechter, M.4    Bienart, R.5    Goldenberg, I.6
  • 49
    • 33749503499 scopus 로고    scopus 로고
    • Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation
    • Geisler T, Langer H, Wydymus M, Gohring K, Zurn C, Bigalke B et al. Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation. Eur Heart J 2006; 27: 2420-2425.
    • (2006) Eur Heart J , vol.27 , pp. 2420-2425
    • Geisler, T.1    Langer, H.2    Wydymus, M.3    Gohring, K.4    Zurn, C.5    Bigalke, B.6
  • 50
    • 79955110460 scopus 로고    scopus 로고
    • Prasugrel overcomes high on-clopidogrel platelet reactivity post-stenting more effectively than high-dose (150-mg) clopidogrel: The importance of CYP2C19∗2 genotyping
    • Alexopoulos D, Dimitropoulos G, Davlouros P, Xanthopoulou I, Kassimis G, Stavrou EF et al. Prasugrel overcomes high on-clopidogrel platelet reactivity post-stenting more effectively than high-dose (150-mg) clopidogrel: the importance of CYP2C19∗2 genotyping. JACC Cardiovasc Interv 2011; 4: 403-410.
    • (2011) JACC Cardiovasc Interv , vol.4 , pp. 403-410
    • Alexopoulos, D.1    Dimitropoulos, G.2    Davlouros, P.3    Xanthopoulou, I.4    Kassimis, G.5    Stavrou, E.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.