Immune activation caused by vascular oxidation promotes fibrosis and hypertension

Journal of Clinical Investigation

Volumn 126, Issue 1, 2016, Pages 50-67

  Wu, Jing ^a   Saleh, Mohamed A ^a,b   Kirabo, Annet ^a   Itani, Hana A ^a   Montaniel, Kim Ramil C ^a   Xiao, Liang ^a   Chen, Wei ^a   Mernaugh, Raymond L ^c   Cai, Hua ^d   Bernstein, Kenneth E ^e   Goronzy, Jörg J ^f   Weyand, Cornelia M ^f   Curci, John A ^a   Barbaro, Natalia R ^g   Moreno, Heitor ^g   Davies, Sean S ^a   Roberts, L Jackson ^a   Madhur, Meena S ^a   Harrison, David G ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b MANSOURA UNIVERSITY   (Egypt)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e CEDARS SINAI MEDICAL CENTER   (United States)

^f STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; COLLAGEN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; EXTRACELLULAR SUPEROXIDE DISMUTASE; GAMMA INTERFERON; GLUCOSE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMOGLOBIN A1C; HYDROXYPROLINE; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; ISOPROSTANE DERIVATIVE; PROTEIN P22; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TAMOXIFEN; TEMPOL; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA3; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

ADOPTIVE TRANSFER; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ANTIHYPERTENSIVE THERAPY; ARTERIAL STIFFNESS; ARTICLE; BLOOD PRESSURE; BODY MASS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ISOLATION; CELL SUSPENSION; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; EX VIVO STUDY; FLOW CYTOMETRY; GLUCOSE BLOOD LEVEL; HEART RATE VARIABILITY; HEMOGLOBIN BLOOD LEVEL; HUMAN; HYPERTENSION; IMMUNE ACTIVATION; IMMUNE RESPONSE; IMMUNOGENICITY; IN VIVO STUDY; KIDNEY FAILURE; LEUKOCYTE COUNT; LIQUID CHROMATOGRAPHY; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MASS SPECTROMETRY; MONOCYTE; MOUSE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; SODIUM EXCRETION; SODIUM LOAD; SYSTOLIC BLOOD PRESSURE; T LYMPHOCYTE ACTIVATION; TELEMETRY; VASCULAR FIBROSIS; VASCULITIS; AGE; ANIMAL; BIOSYNTHESIS; COMPLICATION; FIBROSIS; INFLAMMATION; MALE; METABOLISM; PHYSIOLOGY; T LYMPHOCYTE;

AGE FACTORS; ANIMALS; COLLAGEN; CYTOKINES; FIBROSIS; HUMANS; HYPERTENSION; INFLAMMATION; MALE; MICE; OXIDATIVE STRESS; T-LYMPHOCYTES; VASCULAR STIFFNESS; VASCULITIS;

EID: 84956708183     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI80761     Document Type: Article

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