Localization of isoketal adducts in vivo using a single-chain antibody

Free Radical Biology and Medicine

Volumn 36, Issue 9, 2004, Pages 1163-1174

  Davies, Sean S ^a   Talati, Megha ^b   Wang, Xiahong ^c   Mernaugh, Raymond L ^a   Amarnath, Venkataraman ^b   Fessel, Joshua ^a   Meyrick, Barbara O ^b   Sheller, James ^b   Roberts II, L Jackson ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c VANDERBILT INGRAM CANCER CENTER   (United States)

Author keywords

2,2 azino bis(3 ethylbenzthiazoline 6 sulfonic acid); AA; ABTS; Aldehydes; Anti E monoclonal antibody conjugated with horseradish peroxidase; Anti E HRP; Arachidonic acid; BSA; Free radicals; Hyperoxia; Isoketals; Lipid peroxidation; Protein adducts

Indexed keywords

4 HYDROXYNONENAL; 8 ISOPROSTAGLANDIN F2 ALPHA; AMINO ACID; ISOPROSTANE DERIVATIVE; PEPTIDE; PEPTIDE DERIVATIVE; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

AMBIENT AIR; AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; COMPARATIVE STUDY; EPITHELIUM CELL; HYPEROXIA; IMMUNOREACTIVITY; IN VIVO STUDY; OXIDATION; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM;

ALDEHYDES; ANIMALS; ANTIBODY SPECIFICITY; EPITHELIAL CELLS; EPITOPE MAPPING; FEMALE; HYPEROXIA; IMMUNOCHEMISTRY; IMMUNOGLOBULIN VARIABLE REGION; LIPID PEROXIDATION; LUNG; MICE; MICE, INBRED C57BL; MOLECULAR STRUCTURE; PEPTIDE LIBRARY; PEPTIDES; PROSTAGLANDINS; PROSTAGLANDINS E; PROTEINS; RECOMBINANT PROTEINS;

ANIMALIA; ARMORACIA RUSTICANA;

EID: 1842785821     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2004.02.014     Document Type: Article

References (40)

1. 2-isoprostanes, are present in increased amounts in human atherosclerotic lesions. Arterioscler. Thromb. Vasc. Biol. 17:1997;3236-3241.
2. Oguogho A., Kritz H., Wagner O., Sinzinger H. 6-oxo-PGF(1 alpha)and 8-epi-PGF(2 alpha)in the arterial wall layers of various species: a comparison between intact and atherosclerotic areas. Prostaglandins Leukot. Essent. Fatty Acids. 64:2001;167-171.
3. Pratico D., Tangirala R.K., Horkko S., Witztum J.L., Palinski W., FitzGerald G.A. Circulating autoantibodies to oxidized cardiolipin correlate with isoprostane F(2alpha)-VI levels and the extent of atherosclerosis in ApoE-deficient mice: modulation by vitamin E. Blood. 97:2001;459-464.
4. 2-isoprostane levels are increased in Alzheimer's disease. Ann. Neurol. 44:1998;410-413.
5. 2-isoprostane concentration in probable AD. Neurology. 52:1999;562-565.
6. 2-isoprostanes are elevated in Huntington's disease. Neurology. 52:1999;1104-1105.
7. Reich E.E., Markesbery W.R., Roberts L.J., Swift L.L., Morrow J.D., Montine T.J. Brain regional quantification of F-ring and D-/E-ring isoprostanes and neuroprostanes in Alzheimer's disease. Am. J. Pathol. 158:2001;293-297.
8. Roberts L.J. 2nd, Montine T.J., Markesbery W.R., Tapper A.R., Hardy P., Chemtob S., Dettbarn W.D., Morrow J.D. Formation of isoprostane-like compounds (neuroprostanes) in vivo from docosahexaenoic acid. J. Biol. Chem. 273:1998;13605-13612.
9. Dworski R., Murray J.J., Roberts L.J. 2nd, Oates J.A., Morrow J.D., Fisher L., Sheller J.R. Allergen-induced synthesis of F(2)-isoprostanes in atopic asthmatics. Evidence for oxidant stress. Am. J. Respir. Crit. Care Med. 160:1999;1947-1951.
10. Wood L.G., Fitzgerald D.A., Gibson P.G., Cooper D.M., Garg M.L. Lipid peroxidation as determined by plasma isoprostanes is related to disease severity in mild asthma. Lipids. 35:2000;967-974.
11. Montuschi P., Corradi M., Ciabattoni G., Nightingale J., Kharitonov S.A., Barnes P.J. Increased 8-isoprostane, a marker of oxidative stress, in exhaled condensate of asthma patients. Am. J. Respir. Crit. Care Med. 160:1999;216-220.
12. Antczak A., Montuschi P., Kharitonov S., Gorski P., Barnes P.J. Increased exhaled cysteinyl-leukotrienes and 8-isoprostane in aspirin-induced asthma. Am. J. Respir. Crit. Care Med. 166:2002;301-306.
13. 2-isoprostane, 15-F2t-IsoP (8-iso- PGF2alpha). Clin. Exp. Allergy. 31:2001;387-390.
14. Brame C.J., Salomon R.G., Morrow J.D., Roberts L.J. 2nd Identification of extremely reactive gamma-ketoaldehydes (isolevuglandins) as products of the isoprostane pathway and characterization of their lysyl protein adducts. J. Biol. Chem. 274:1999;13139-13146.
15. 2, a product of the isoprostane pathway, in oxidized low density lipoprotein. J. Biol. Chem. 274:1999;20271-20280.
16. Taber D.F., Morrow J.D., Roberts L.J. 2nd A nomenclature system for the isoprostanes. Prostaglandins. 53:1997;63-67.
17. 2-isoprostane pathway. Chem. Phys. Lipids. 128:2004;85-99.
18. Salomon R.G., Miller D.B. Levuglandins: isolation, characterization, and total synthesis of new secoprostanoid products from prostaglandin endoperoxides. Adv. Prostaglandin Thromboxane Leukot. Res. 15:1985;323-326.
19. 2 with proteins. Prostaglandins. 34:1987;643-656.
20. 2 synthase-dependent pathway after platelet activation. J. Biol. Chem. 11:2003;11.
21. Salomon R.G., Batyreva E., Kaur K., Sprecher D.L., Schreiber M.J., Crabb J.W., Penn M.S., DiCorletoe A.M., Hazen S.L., Podrez E.A. Isolevuglandin-protein adducts in humans: products of free radical-induced lipid oxidation through the isoprostane pathway. Biochim. Biophys. Acta. 1485:2000;225-235.
22. Boutaud O., Li J., Chaurand P., Brame C.J., Marnett L.J., Roberts L.J., Oates J.A. Oxygenation of arachidonic acid by cyclooxygenases generates reactive intermediates that form adducts with proteins. Adv. Exp. Med. Biol. 500:2001;133-137.
23. Davies S.S., Amarnath V., Montine K.S., Bernoud-Hubac N., Boutaud O., Montine T.J., Roberts L.J. 2nd Effects of reactive gamma-ketoaldehydes formed by the isoprostane pathway (isoketals) and cyclooxygenase pathway (levuglandins) on proteasome function. FASEB J. 16:2002;715-717.
24. 2 inhibits mitosis and microtubule assembly. Prostaglandins. 39:1990;611-622.
25. 2, an oxidation product of arachidonic acid. Biochim. Biophys. Acta. 1344:1997;1-5.
26. 2. Biochemistry. 32:1993;4090-4097.
27. Freeman B.A., Crapo J.D. Hyperoxia increases oxygen radical production in rat lungs and lung mitochondria. J. Biol. Chem. 256:1981;10986-10992.
28. Freeman B.A., Topolosky M.K., Crapo J.D. Hyperoxia increases oxygen radical production in rat lung homogenates. Arch. Biochem. Biophys. 216:1982;477-484.
29. Fessel J.P., Porter N.A., Moore K.P., Sheller J.R., Roberts L.J. 2nd Discovery of lipid peroxidation products formed in vivo with a substituted tetrahydrofuran ring (isofurans) that are favored by increased oxygen tension. Proc. Natl. Acad. Sci. USA. 99:2002;16713-16718.
30. Loiseaux-Meunier M.N., Bedu M., Gentou C., Pepin D., Coudert J., Caillaud D. Oxygen toxicity: simultaneous measure of pentane and malondialdehyde in humans exposed to hyperoxia. Biomed. Pharmacother. 55:2001;163-169.
31. Crapo J.D. Morphologic changes in pulmonary oxygen toxicity. Annu. Rev. Physiol. 48:1986;721-731.
32. O'Reilly M.A., Staversky R.J., Stripp B.R., Finkelstein J.N. Exposure to hyperoxia induces p53 expression in mouse lung epithelium. Am. J. Respir. Cell. Mol. Biol. 18:1998;43-50.
33. 2. J. Am. Chem. Soc. 106:1984;8296-8298.
34. Dawling S., Roodi N., Mernaugh R.L., Wang X., Parl F.F. Catechol-O-methyltransferase (COMT)-mediated metabolism of catechol estrogens: comparison of wild-type and variant COMT isoforms. Cancer Res. 61:2001;6716-6722.
35. Pope A.R., Embelton M.J., Mernaugh R.L. Construction and use of antibody gene repertoires. McCafferty J., Chiswell D. Antibody engineering: a practical approach. 1996;1-40 IRL Press, New York.
36. 2-isoprostanes and malondialdehyde in peroxidizing rat liver microsomes. Biochem. Pharmacol. 47:1994;1173-1177.
37. Bernoud-Hubac N., Davies S.S., Boutaud O., Montine T.J., Roberts L.J. 2nd Formation of highly reactive gamma-ketoaldehydes (neuroketals) as products of the neuroprostane pathway. J. Biol. Chem. 276:2001;30964-30970.
38. Gardner H.W., Bartlet R.J., Weisleder D. A facile synthesis of 4-hydroxy-2(E)-nonenal. Lipids. 27:1992;686-689.
39. Amarnath V., Valentine W.M., Montine T.J., Patterson W.H., Amarnath K., Bassett C.N., Graham D.G. Reactions of 4-hydroxy-2(E)-nonenal and related aldehydes with proteins studied by carbon-13 nuclear magnetic resonance spectroscopy. Chem. Res. Toxicol. 11:1998;317-328.
40. Scarpa M., Viglino P., Contri D., Rigo A. Generation of superoxide ion in human red blood cell lysates. J. Biol. Chem. 259:1984;10657-10659.