KIF1A inhibition immortalizes brain stem cells but blocks BDNF-mediated neuronal migration

Nature Neuroscience

Volumn 19, Issue 2, 2016, Pages 253-262

  Carabalona, Aurelie ^a   Hu, Daniel Jun Kit ^a   Vallee, Richard B ^a  

^a Department of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; COMPLEMENTARY DNA; DOUBLECORTIN; MOLECULAR MOTOR; PROTEIN; PROTEIN KIF1A; PROTEIN TBR1; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; DIFFERENTIATION ANTIGEN; KIF1A PROTEIN, HUMAN; KIF1A PROTEIN, RAT; KINESIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CELL CYCLE PROGRESSION; CELL FATE; CELL IMMORTALIZATION; CELL MIGRATION; CONTROLLED STUDY; ECTOPIC EXPRESSION; ELECTROPORATION; EMBRYO; GENE SILENCING; IMMUNOHISTOCHEMISTRY; INTERKINETIC NUCLEAR MIGRATION; MACROGLIA; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RNA INTERFERENCE; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CYCLE; CELL MOTION; DRUG EFFECTS; FEMALE; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MITOSIS; NERVE CELL; PREGNANCY; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIGENS, DIFFERENTIATION; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL CYCLE; CELL MOVEMENT; FEMALE; HUMANS; KINESIN; MITOSIS; NEURAL STEM CELLS; NEURONS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; TRANSFECTION;

EID: 84956685754     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.4213     Document Type: Article

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