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Volumn 470, Issue 1, 2016, Pages 1-8

LYATK1 potently inhibits LPS-mediated pro-inflammatory response

Author keywords

LPS; LYTAK1; Monocytes macrophages and inflammation; TAK1 signalings

Indexed keywords

CYTOKINE; ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN SERINE THREONINE KINASE INHIBITOR; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1 INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; MAP KINASE KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; PROTEIN KINASE INHIBITOR;

EID: 84956591965     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.11.090     Document Type: Article
Times cited : (9)

References (31)
  • 1
    • 0037180812 scopus 로고    scopus 로고
    • Points of control in inflammation
    • C. Nathan Points of control in inflammation Nature 420 2002 846 852
    • (2002) Nature , vol.420 , pp. 846-852
    • Nathan, C.1
  • 3
    • 25844459154 scopus 로고    scopus 로고
    • NF-kappaB: linking inflammation and immunity to cancer development and progression
    • M. Karin, and F.R. Greten NF-kappaB: linking inflammation and immunity to cancer development and progression Nat. Rev. Immunol. 5 2005 749 759
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 749-759
    • Karin, M.1    Greten, F.R.2
  • 4
    • 33845890803 scopus 로고    scopus 로고
    • Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation
    • S. Mariathasan, and D.M. Monack Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation Nat. Rev. Immunol. 7 2007 31 40
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 31-40
    • Mariathasan, S.1    Monack, D.M.2
  • 5
    • 3543102542 scopus 로고    scopus 로고
    • Inflammation and necrosis promote tumour growth
    • J. Vakkila, and M.T. Lotze Inflammation and necrosis promote tumour growth Nat. Rev. Immunol. 4 2004 641 648
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 641-648
    • Vakkila, J.1    Lotze, M.T.2
  • 7
    • 0034680145 scopus 로고    scopus 로고
    • Toll-like receptors in the induction of the innate immune response
    • A. Aderem, and R.J. Ulevitch Toll-like receptors in the induction of the innate immune response Nature 406 2000 782 787
    • (2000) Nature , vol.406 , pp. 782-787
    • Aderem, A.1    Ulevitch, R.J.2
  • 9
    • 84866731086 scopus 로고    scopus 로고
    • Targeting of TAK1 in inflammatory disorders and cancer
    • H. Sakurai Targeting of TAK1 in inflammatory disorders and cancer Trends Pharmacol. Sci. 33 2012 522 530
    • (2012) Trends Pharmacol. Sci. , vol.33 , pp. 522-530
    • Sakurai, H.1
  • 10
    • 0033952268 scopus 로고    scopus 로고
    • TAK1 mediates an activation signal from toll-like receptor(s) to nuclear factor-kappaB in lipopolysaccharide-stimulated macrophages
    • T. Irie, T. Muta, and K. Takeshige TAK1 mediates an activation signal from toll-like receptor(s) to nuclear factor-kappaB in lipopolysaccharide-stimulated macrophages FEBS Lett. 467 2000 160 164
    • (2000) FEBS Lett. , vol.467 , pp. 160-164
    • Irie, T.1    Muta, T.2    Takeshige, K.3
  • 11
    • 84880847105 scopus 로고    scopus 로고
    • Cell type-specific function of TAK1 in innate immune signaling
    • A.A. Ajibade, H.Y. Wang, and R.F. Wang Cell type-specific function of TAK1 in innate immune signaling Trends Immunol. 34 2013 307 316
    • (2013) Trends Immunol. , vol.34 , pp. 307-316
    • Ajibade, A.A.1    Wang, H.Y.2    Wang, R.F.3
  • 13
    • 0033669743 scopus 로고    scopus 로고
    • TAK1 regulates multiple protein kinase cascades activated by bacterial lipopolysaccharide
    • J. Lee, L. Mira-Arbibe, and R.J. Ulevitch TAK1 regulates multiple protein kinase cascades activated by bacterial lipopolysaccharide J. Leukoc. Biol. 68 2000 909 915
    • (2000) J. Leukoc. Biol. , vol.68 , pp. 909-915
    • Lee, J.1    Mira-Arbibe, L.2    Ulevitch, R.J.3
  • 14
    • 33748752805 scopus 로고    scopus 로고
    • The IRAK-1-BCL10-MALT1-TRAF6-TAK1 cascade mediates signaling to NF-kappaB from Toll-like receptor 4
    • W. Dong, Y. Liu, J. Peng, L. Chen, T. Zou, H. Xiao, Z. Liu, W. Li, Y. Bu, and Y. Qi The IRAK-1-BCL10-MALT1-TRAF6-TAK1 cascade mediates signaling to NF-kappaB from Toll-like receptor 4 J. Biol. Chem. 281 2006 26029 26040
    • (2006) J. Biol. Chem. , vol.281 , pp. 26029-26040
    • Dong, W.1    Liu, Y.2    Peng, J.3    Chen, L.4    Zou, T.5    Xiao, H.6    Liu, Z.7    Li, W.8    Bu, Y.9    Qi, Y.10
  • 16
    • 84908373317 scopus 로고    scopus 로고
    • Identification of TGF-beta-activated kinase 1 as a possible novel target for renal cell carcinoma intervention
    • F. Meng, Y. Li, X. Tian, L. Fu, Y. Yin, C. Sui, P. Ma, and Y. Jiang Identification of TGF-beta-activated kinase 1 as a possible novel target for renal cell carcinoma intervention Biochem. Biophys. Res. Commun. 453 2014 106 111
    • (2014) Biochem. Biophys. Res. Commun. , vol.453 , pp. 106-111
    • Meng, F.1    Li, Y.2    Tian, X.3    Fu, L.4    Yin, Y.5    Sui, C.6    Ma, P.7    Jiang, Y.8
  • 17
    • 84939574466 scopus 로고    scopus 로고
    • Inhibition of ovarian cancer cell growth by a novel TAK1 inhibitor LYTAK1
    • L. Ying, Y. Chunxia, and L. Wei Inhibition of ovarian cancer cell growth by a novel TAK1 inhibitor LYTAK1 Cancer Chemother. Pharmacol. 76 2015 641 650
    • (2015) Cancer Chemother. Pharmacol. , vol.76 , pp. 641-650
    • Ying, L.1    Chunxia, Y.2    Wei, L.3
  • 18
    • 84929965350 scopus 로고    scopus 로고
    • LYTAK1, a novel TAK1 inhibitor, suppresses KRAS mutant colorectal cancer cell growth in vitro and in vivo
    • J. Zhou, B. Zheng, J. Ji, F. Shen, H. Min, B. Liu, J. Wu, and S. Zhang LYTAK1, a novel TAK1 inhibitor, suppresses KRAS mutant colorectal cancer cell growth in vitro and in vivo Tumour Biol. 36 2015 3301 3308
    • (2015) Tumour Biol. , vol.36 , pp. 3301-3308
    • Zhou, J.1    Zheng, B.2    Ji, J.3    Shen, F.4    Min, H.5    Liu, B.6    Wu, J.7    Zhang, S.8
  • 19
    • 84924049107 scopus 로고    scopus 로고
    • Trametinib, a novel MEK kinase inhibitor, suppresses lipopolysaccharide-induced tumor necrosis factor (TNF)-alpha production and endotoxin shock
    • S.L. Du, X. Yuan, S. Zhan, L.J. Tang, and C.Y. Tong Trametinib, a novel MEK kinase inhibitor, suppresses lipopolysaccharide-induced tumor necrosis factor (TNF)-alpha production and endotoxin shock Biochem. Biophys. Res. Commun. 458 2015 667 673
    • (2015) Biochem. Biophys. Res. Commun. , vol.458 , pp. 667-673
    • Du, S.L.1    Yuan, X.2    Zhan, S.3    Tang, L.J.4    Tong, C.Y.5
  • 20
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 2001 402 408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 21
    • 84904166794 scopus 로고    scopus 로고
    • Cordycepin inhibits lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-alpha production via activating amp-activated protein kinase (AMPK) signaling
    • J.L. Zhang, Y. Xu, and J. Shen Cordycepin inhibits lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-alpha production via activating amp-activated protein kinase (AMPK) signaling Int. J. Mol. Sci. 15 2014 12119 12134
    • (2014) Int. J. Mol. Sci. , vol.15 , pp. 12119-12134
    • Zhang, J.L.1    Xu, Y.2    Shen, J.3
  • 22
    • 84876536136 scopus 로고    scopus 로고
    • Saikosaponin A mediates the inflammatory response by inhibiting the MAPK and NF-kappaB pathways in LPS-stimulated RAW 264.7 cells
    • J. Zhu, C. Luo, P. Wang, Q. He, J. Zhou, and H. Peng Saikosaponin A mediates the inflammatory response by inhibiting the MAPK and NF-kappaB pathways in LPS-stimulated RAW 264.7 cells Exp. Ther. Med. 5 2013 1345 1350
    • (2013) Exp. Ther. Med. , vol.5 , pp. 1345-1350
    • Zhu, J.1    Luo, C.2    Wang, P.3    He, Q.4    Zhou, J.5    Peng, H.6
  • 24
    • 84937965585 scopus 로고    scopus 로고
    • Dexamethasone-induced apoptosis of osteocytic and osteoblastic cells is mediated by TAK1 activation
    • H. Ding, T. Wang, D. Xu, B. Cha, J. Liu, and Y. Li Dexamethasone-induced apoptosis of osteocytic and osteoblastic cells is mediated by TAK1 activation Biochem. Biophys. Res. Commun. 460 2015 157 163
    • (2015) Biochem. Biophys. Res. Commun. , vol.460 , pp. 157-163
    • Ding, H.1    Wang, T.2    Xu, D.3    Cha, B.4    Liu, J.5    Li, Y.6
  • 25
    • 69749113182 scopus 로고    scopus 로고
    • WRN helicase promotes repair of DNA double-strand breaks caused by aberrant mismatch repair of chromium-DNA adducts
    • A. Zecevic, H. Menard, V. Gurel, E. Hagan, R. DeCaro, and A. Zhitkovich WRN helicase promotes repair of DNA double-strand breaks caused by aberrant mismatch repair of chromium-DNA adducts Cell Cycle 8 2009 2769 2778
    • (2009) Cell Cycle , vol.8 , pp. 2769-2778
    • Zecevic, A.1    Menard, H.2    Gurel, V.3    Hagan, E.4    DeCaro, R.5    Zhitkovich, A.6
  • 26
    • 0037903145 scopus 로고    scopus 로고
    • A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase
    • J. Ninomiya-Tsuji, T. Kajino, K. Ono, T. Ohtomo, M. Matsumoto, M. Shiina, M. Mihara, M. Tsuchiya, and K. Matsumoto A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase J. Biol. Chem. 278 2003 18485 18490
    • (2003) J. Biol. Chem. , vol.278 , pp. 18485-18490
    • Ninomiya-Tsuji, J.1    Kajino, T.2    Ono, K.3    Ohtomo, T.4    Matsumoto, M.5    Shiina, M.6    Mihara, M.7    Tsuchiya, M.8    Matsumoto, K.9
  • 27
    • 78650679421 scopus 로고    scopus 로고
    • Total synthesis of LL-Z1640-2 utilizing a late-stage intramolecular Nozaki-Hiyama-Kishi reaction
    • C.A. Leclair, M.B. Boxer, C.J. Thomas, and D.J. Maloney Total synthesis of LL-Z1640-2 utilizing a late-stage intramolecular Nozaki-Hiyama-Kishi reaction Tetrahedron Lett. 51 2010 6852 6855
    • (2010) Tetrahedron Lett. , vol.51 , pp. 6852-6855
    • Leclair, C.A.1    Boxer, M.B.2    Thomas, C.J.3    Maloney, D.J.4
  • 30
    • 0036781052 scopus 로고    scopus 로고
    • NF-kappaB regulation in the immune system
    • Q. Li, and I.M. Verma NF-kappaB regulation in the immune system Nat. Rev. Immunol. 2 2002 725 734
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 31
    • 84897116583 scopus 로고    scopus 로고
    • Inflammation: TNF snuffs out steroids
    • Y. Bordon Inflammation: TNF snuffs out steroids Nat. Rev. Immunol. 14 2014 214
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 214
    • Bordon, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.