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Volumn 12, Issue 2, 2016, Pages 575-587

Enhancing specificity in the Janus kinases: A study on the thienopyridine JAK2 selective mechanism combined molecular dynamics simulation

(5) Li, Jiao Jiao a Cheng, Peng a Tu, Jing a Zhai, Hong Lin a Zhang, Xiao Yun a

a LANZHOU UNIVERSITY (China)

Author keywords

[No Author keywords available]

Indexed keywords

JAK2 PROTEIN, HUMAN; JANUS KINASE 2; PROTEIN BINDING; PROTEIN KINASE INHIBITOR; PYRIDINE DERIVATIVE; THIENOPYRIDINE DERIVATIVE;

AMINO ACID SEQUENCE; ANTAGONISTS AND INHIBITORS; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; HUMAN; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR GENETICS; THERMODYNAMICS;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; HUMANS; HYDROGEN BONDING; JANUS KINASE 2; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PYRIDINES; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 84956508090 PISSN: 1742206X EISSN: 17422051 Source Type: Journal
DOI: 10.1039/c5mb00747j Document Type: Article

Times cited : (11)

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