Antidepressant-like effects and possible mechanisms of amantadine on cognitive and synaptic deficits in a rat model of chronic stress

Stress

Volumn 19, Issue 1, 2016, Pages 104-113

  Yu, Mei ^a   Zhang, Yuan ^a   Chen, Xiaoyu ^a   Zhang, Tao ^a  

^a NANKAI UNIVERSITY   (China)

Author keywords

Amantadine; chronic stress; cognition; NR2B; PSD 95; synaptic plasticity

Indexed keywords

AMANTADINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; POSTSYNAPTIC DENSITY PROTEIN 95; ANTIDEPRESSANT AGENT; DLGH4 PROTEIN, RAT; MEMBRANE PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NR2B NMDA RECEPTOR; SIGNAL PEPTIDE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; ARTICLE; BODY WEIGHT; CHRONIC STRESS; CHRONIC UNPREDICTABLE STRESS; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG MECHANISM; EXCITATORY POSTSYNAPTIC POTENTIAL; FOOD DEPRIVATION; HIPPOCAMPAL CA1 REGION; LEARNING; LIGHT DARK CYCLE; LONG TERM POTENTIATION; MALE; MORRIS WATER MAZE TEST; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPATIAL MEMORY; SUCROSE PREFERENCE TEST; TREATMENT DURATION; WATER DEPRIVATION; ANIMAL; COGNITION; COGNITION DISORDERS; DEPRESSION; DRUG EFFECTS; HIPPOCAMPUS; MENTAL STRESS; METABOLISM; WESTERN BLOTTING; WISTAR RAT;

AMANTADINE; ANIMALS; ANTIDEPRESSIVE AGENTS; BLOTTING, WESTERN; CA1 REGION, HIPPOCAMPAL; COGNITION; COGNITION DISORDERS; DEPRESSION; HIPPOCAMPUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LONG-TERM POTENTIATION; MALE; MEMBRANE PROTEINS; NEURONAL PLASTICITY; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; STRESS, PSYCHOLOGICAL;

EID: 84955692969     PISSN: 10253890     EISSN: 16078888     Source Type: Journal    
DOI: 10.3109/10253890.2015.1108302     Document Type: Article

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