메뉴 건너뛰기




Volumn 96, Issue 2, 2016, Pages 218-229

WNT/β-catenin signaling regulates cigarette smoke-induced airway inflammation via the PPARδ/p38 pathway

Author keywords

[No Author keywords available]

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BETA CATENIN; CIGARETTE SMOKE; CYCLIN D1; FRIZZLED PROTEIN; FZD1 PROTEIN; GELATINASE A; GELATINASE B; INTERLEUKIN 1BETA; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 5; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; LYMPHOID ENHANCER FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PROTEIN; SMALL INTERFERING RNA; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TCF4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; WNT PROTEIN; WNT RECEPTOR FZD4; WNT3A PROTEIN; WNT7B PROTEIN; [4 [2 (3 FLUORO 4 TRIFLUOROMETHYLPHENYL) 4 METHYL 5 THIAZOLYLMETHYLTHIO] 2 METHYLPHENOXY]ACETIC ACID; SMOKE;

EID: 84955590917     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2015.101     Document Type: Article
Times cited : (44)

References (48)
  • 1
    • 33845793416 scopus 로고    scopus 로고
    • Airway inflammation contributes to health status in COPD: A cross-sectional study
    • Snoeck-Stroband JB, Postma DS, Lapperre TS et al. Airway inflammation contributes to health status in COPD: a cross-sectional study. Respir Res 2006;7:140.
    • (2006) Respir Res , vol.7 , pp. 140
    • Snoeck-Stroband, J.B.1    Postma, D.S.2    Lapperre, T.S.3
  • 2
    • 1842552109 scopus 로고    scopus 로고
    • Standards for the diagnosis and treatment of patients with COPD: A summary of the ATS/ERS position paper
    • Celli BR, MacNee W. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper. Eur Respir J 2004;23:932-946.
    • (2004) Eur Respir J , vol.23 , pp. 932-946
    • Celli, B.R.1    Macnee, W.2
  • 3
    • 84873956600 scopus 로고    scopus 로고
    • Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary
    • Vestbo J, Hurd SS, Agusti AG et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med 2013;187:347-365.
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 347-365
    • Vestbo, J.1    Hurd, S.S.2    Agusti, A.G.3
  • 4
    • 0035744614 scopus 로고    scopus 로고
    • Cytokines in chronic obstructive pulmonary disease
    • Chung KF. Cytokines in chronic obstructive pulmonary disease. Eur Respir J Suppl 2001;34:50s-59s.
    • (2001) Eur Respir J Suppl , vol.34 , pp. 50s-59s
    • Chung, K.F.1
  • 5
    • 84893401365 scopus 로고    scopus 로고
    • Airway epithelial regulation of pulmonary immune homeostasis and inflammation
    • Hallstrand TS, Hackett TL, Altemeier WA et al. Airway epithelial regulation of pulmonary immune homeostasis and inflammation. Clin Immunol 2014;151:1-15.
    • (2014) Clin Immunol , vol.151 , pp. 1-15
    • Hallstrand, T.S.1    Hackett, T.L.2    Altemeier, W.A.3
  • 6
    • 27944500309 scopus 로고    scopus 로고
    • Beta-catenin regulates differentiation of respiratory epithelial cells in vivo
    • Mucenski ML, Nation JM, Thitoff AR et al. Beta-catenin regulates differentiation of respiratory epithelial cells in vivo. Am J Physiol Lung Cell Mol Physiol 2005;289:L971-L979.
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.289 , pp. L971-L979
    • Mucenski, M.L.1    Nation, J.M.2    Thitoff, A.R.3
  • 7
    • 84874198121 scopus 로고    scopus 로고
    • Activation of canonical wnt pathway promotes differentiation of mouse bone marrow-derived MSCs into type II alveolar epithelial cells, confers resistance to oxidative stress, and promotes their migration to injured lung tissue in vitro
    • Liu AR, Liu L, Chen S et al. Activation of canonical wnt pathway promotes differentiation of mouse bone marrow-derived MSCs into type II alveolar epithelial cells, confers resistance to oxidative stress, and promotes their migration to injured lung tissue in vitro. J Cell Physiol 2013;228:1270-1283.
    • (2013) J Cell Physiol , vol.228 , pp. 1270-1283
    • Liu, A.R.1    Liu, L.2    Chen, S.3
  • 8
    • 73949090577 scopus 로고    scopus 로고
    • WNT signaling in lung disease: A failure or a regeneration signal?
    • Königshoff M, Eickelberg O. WNT signaling in lung disease: a failure or a regeneration signal? Am J Respir Cell Mol Biol 2010;42:21-31.
    • (2010) Am J Respir Cell Mol Biol , vol.42 , pp. 21-31
    • Königshoff, M.1    Eickelberg, O.2
  • 9
    • 84904266980 scopus 로고    scopus 로고
    • The Wnt/beta-catenin pathway attenuates experimental allergic airway disease
    • Reuter S, Martin H, Beckert H et al. The Wnt/beta-catenin pathway attenuates experimental allergic airway disease. J Immunol 2014;193: 485-495.
    • (2014) J Immunol , vol.193 , pp. 485-495
    • Reuter, S.1    Martin, H.2    Beckert, H.3
  • 10
    • 51149118892 scopus 로고    scopus 로고
    • Deciphering the function of canonical Wnt signals in development and disease: Conditional loss-and gain-of-function mutations of beta-catenin in mice
    • Grigoryan T, Wend P, Klaus A et al. Deciphering the function of canonical Wnt signals in development and disease: conditional loss-and gain-of-function mutations of beta-catenin in mice. Genes Dev 2008;22:2308-2341.
    • (2008) Genes Dev , vol.22 , pp. 2308-2341
    • Grigoryan, T.1    Wend, P.2    Klaus, A.3
  • 11
    • 58149306391 scopus 로고    scopus 로고
    • Transcriptional outcome of Wnt-Frizzled signal transduction in inflammation: Evolving concepts
    • Sen M, Ghosh G. Transcriptional outcome of Wnt-Frizzled signal transduction in inflammation: evolving concepts. J Immunol 2008;181: 4441-4445.
    • (2008) J Immunol , vol.181 , pp. 4441-4445
    • Sen, M.1    Ghosh, G.2
  • 12
    • 79952715657 scopus 로고    scopus 로고
    • Activation of the WNT/beta-catenin pathway attenuates experimental emphysema
    • Kneidinger N, Yildirim AO, Callegari J et al. Activation of the WNT/beta-catenin pathway attenuates experimental emphysema. Am J Respir Crit Care Med 2011;183:723-733.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 723-733
    • Kneidinger, N.1    Yildirim, A.O.2    Callegari, J.3
  • 13
    • 79954527594 scopus 로고    scopus 로고
    • Down-regulation of the canonical Wnt beta-catenin pathway in the airway epithelium of healthy smokers and smokers with COPD
    • Wang R, Ahmed J, Wang G et al. Down-regulation of the canonical Wnt beta-catenin pathway in the airway epithelium of healthy smokers and smokers with COPD. PLoS One 2011;6:e14793.
    • (2011) PLoS One , vol.6 , pp. e14793
    • Wang, R.1    Ahmed, J.2    Wang, G.3
  • 14
    • 80053615345 scopus 로고    scopus 로고
    • Activation of WNT/beta-catenin signaling in pulmonary fibroblasts by TGF-beta(1) is increased in chronic obstructive pulmonary disease
    • Baarsma HA, Spanjer AI, Haitsma G et al. Activation of WNT/beta-catenin signaling in pulmonary fibroblasts by TGF-beta(1) is increased in chronic obstructive pulmonary disease. PLoS One 2011;6:e25450.
    • (2011) PLoS One , vol.6 , pp. e25450
    • Baarsma, H.A.1    Spanjer, A.I.2    Haitsma, G.3
  • 15
    • 41649098360 scopus 로고    scopus 로고
    • A small-molecule inhibitor of Tcf/beta-catenin signaling down-regulates PPARgamma and PPARdelta activities
    • Handeli S, Simon JA. A small-molecule inhibitor of Tcf/beta-catenin signaling down-regulates PPARgamma and PPARdelta activities. Mol Cancer Ther 2008;7:521-529.
    • (2008) Mol Cancer Ther , vol.7 , pp. 521-529
    • Handeli, S.1    Simon, J.A.2
  • 16
    • 0033615352 scopus 로고    scopus 로고
    • PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs
    • He TC, Chan TA, Vogelstein B et al. PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell 1999;99:335-345.
    • (1999) Cell , vol.99 , pp. 335-345
    • He, T.C.1    Chan, T.A.2    Vogelstein, B.3
  • 17
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann I, Green S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 1990;347: 645-650.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 18
    • 80053064710 scopus 로고    scopus 로고
    • GW501516, a PPARdelta agonist, ameliorates tubulointerstitial inflammation in proteinuric kidney disease via inhibition of TAK1-NFkappaB pathway in mice
    • Yang X, Kume S, Tanaka Y et al. GW501516, a PPARdelta agonist, ameliorates tubulointerstitial inflammation in proteinuric kidney disease via inhibition of TAK1-NFkappaB pathway in mice. PLoS One 2011;6:e25271.
    • (2011) PLoS One , vol.6 , pp. e25271
    • Yang, X.1    Kume, S.2    Tanaka, Y.3
  • 19
    • 84870067162 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor delta inhibits human macrophage foam cell formation and the inflammatory response induced by very low-density lipoprotein
    • Bojic LA, Sawyez CG, Telford DE et al. Activation of peroxisome proliferator-activated receptor delta inhibits human macrophage foam cell formation and the inflammatory response induced by very low-density lipoprotein. Arterioscler Thromb Vasc Biol 2012;32:2919-2928.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 2919-2928
    • Bojic, L.A.1    Sawyez, C.G.2    Telford, D.E.3
  • 20
    • 33744519163 scopus 로고    scopus 로고
    • PPARdelta modulates lipopolysaccharide-induced TNFalpha inflammation signaling in cultured cardiomyocytes
    • Ding G, Cheng L, Qin Q et al. PPARdelta modulates lipopolysaccharide-induced TNFalpha inflammation signaling in cultured cardiomyocytes. J Mol Cell Cardiol 2006;40:821-828.
    • (2006) J Mol Cell Cardiol , vol.40 , pp. 821-828
    • Ding, G.1    Cheng, L.2    Qin, Q.3
  • 21
    • 38549127422 scopus 로고    scopus 로고
    • Suppression of pro-inflammatory adhesion molecules by PPAR-delta in human vascular endothelial cells
    • Fan Y, Wang Y, Tang Z et al. Suppression of pro-inflammatory adhesion molecules by PPAR-delta in human vascular endothelial cells. Arter-ioscler Thromb Vasc Biol 2008;28:315-321.
    • (2008) Arter-ioscler Thromb Vasc Biol , vol.28 , pp. 315-321
    • Fan, Y.1    Wang, Y.2    Tang, Z.3
  • 22
    • 84862101929 scopus 로고    scopus 로고
    • Ox-LDL-induced TGF-beta1 production in human alveolar epithelial cells: Involvement of the Ras/ERK/PLTP pathway
    • Guo LL, Chen YJ, Wang T et al. Ox-LDL-induced TGF-beta1 production in human alveolar epithelial cells: involvement of the Ras/ERK/PLTP pathway. J Cell Physiol 2012;227:3185-3191.
    • (2012) J Cell Physiol , vol.227 , pp. 3185-3191
    • Guo, L.L.1    Chen, Y.J.2    Wang, T.3
  • 23
    • 84877030479 scopus 로고    scopus 로고
    • Nuclear β-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer
    • Li X-Q, Yang X-L, Zhang G et al. Nuclear β-catenin accumulation is associated with increased expression of Nanog protein and predicts poor prognosis of non-small cell lung cancer. J Transl Med 2013;11:114.
    • (2013) J Transl Med , vol.11 , pp. 114
    • Li, X.-Q.1    Yang, X.-L.2    Zhang, G.3
  • 24
    • 0032431279 scopus 로고    scopus 로고
    • The expression of beta-catenin in non-small-cell lung cancer: A clinicopathological study
    • Retera JM, Leers MP, Sulzer MA et al. The expression of beta-catenin in non-small-cell lung cancer: a clinicopathological study. J Clin Pathol 1998;51:891-894.
    • (1998) J Clin Pathol , vol.51 , pp. 891-894
    • Retera, J.M.1    Leers, M.P.2    Sulzer, M.A.3
  • 25
    • 84879366798 scopus 로고    scopus 로고
    • The role of p21 Waf1/Cip1 in large airway epithelium in smokers with and without COPD
    • Chiappara G, Gjomarkaj M, Virzi A et al. The role of p21 Waf1/Cip1 in large airway epithelium in smokers with and without COPD. Biochim Biophys Acta 2013;1832:1473-1481.
    • (2013) Biochim Biophys Acta , vol.1832 , pp. 1473-1481
    • Chiappara, G.1    Gjomarkaj, M.2    Virzi, A.3
  • 26
    • 77952135897 scopus 로고    scopus 로고
    • Beta-catenin does not regulate memory T cell phenotype
    • Driessens G, Zheng Y, Gajewski TF. Beta-catenin does not regulate memory T cell phenotype. Nat Med 2010;16:513-514.
    • (2010) Nat Med , vol.16 , pp. 513-514
    • Driessens, G.1    Zheng, Y.2    Gajewski, T.F.3
  • 27
    • 79959367476 scopus 로고    scopus 로고
    • Inhibition of adipocytogenesis by canonical WNT signaling in human mesenchymal stem cells
    • Shen L, Glowacki J, Zhou S. Inhibition of adipocytogenesis by canonical WNT signaling in human mesenchymal stem cells. Exp Cell Res 2011;317:1796-1803.
    • (2011) Exp Cell Res , vol.317 , pp. 1796-1803
    • Shen, L.1    Glowacki, J.2    Zhou, S.3
  • 28
    • 41949123156 scopus 로고    scopus 로고
    • PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis
    • Takata Y, Liu J, Yin F et al. PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis. Proc Natl Acad Sci USA 2008;105:4277-4282.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 4277-4282
    • Takata, Y.1    Liu, J.2    Yin, F.3
  • 29
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • Logan CY, Nusse R. The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 2004;20:781-810.
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 30
    • 84879941977 scopus 로고    scopus 로고
    • Role of aberrant WNT signalling in the airway epithelial response to cigarette smoke in chronic obstructive pulmonary disease
    • Heijink IH, de Bruin HG, van den Berge M et al. Role of aberrant WNT signalling in the airway epithelial response to cigarette smoke in chronic obstructive pulmonary disease. Thorax 2013;68: 709-716.
    • (2013) Thorax , vol.68 , pp. 709-716
    • Heijink, I.H.1    De Bruin, H.G.2    Van Den Berge, M.3
  • 31
    • 84878768846 scopus 로고    scopus 로고
    • Regulation of Wnt4 in chronic obstructive pulmonary disease
    • Durham AL, McLaren A, Hayes BP et al. Regulation of Wnt4 in chronic obstructive pulmonary disease. FASEB J 2013;27:2367-2381.
    • (2013) FASEB J , vol.27 , pp. 2367-2381
    • Durham, A.L.1    McLaren, A.2    Hayes, B.P.3
  • 32
    • 84876460403 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor delta protects against obesity-related glomerulopathy through the P38 MAPK pathway
    • Yan Z, Ni Y, Wang P et al. Peroxisome proliferator-activated receptor delta protects against obesity-related glomerulopathy through the P38 MAPK pathway. Obesity (Silver Spring) 2013;21:538-545.
    • (2013) Obesity (Silver Spring) , vol.21 , pp. 538-545
    • Yan, Z.1    Ni, Y.2    Wang, P.3
  • 33
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
    • Johnson GL, Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002;298: 1911-1912.
    • (2002) Science , vol.298 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 35
    • 36849072463 scopus 로고    scopus 로고
    • Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macro-phages
    • Birrell MA, Wong S, Catley MC et al. Impact of tobacco-smoke on key signaling pathways in the innate immune response in lung macro-phages. J Cell Physiol 2008;214:27-37.
    • (2008) J Cell Physiol , vol.214 , pp. 27-37
    • Birrell, M.A.1    Wong, S.2    Catley, M.C.3
  • 36
    • 66149192420 scopus 로고    scopus 로고
    • Alpha, beta-unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases
    • Moretto N, Facchinetti F, Southworth T et al. Alpha, beta-unsaturated aldehydes contained in cigarette smoke elicit IL-8 release in pulmonary cells through mitogen-activated protein kinases. Am J Physiol Lung Cell Mol Physiol 2009;296:L839-L848.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.296 , pp. L839-L848
    • Moretto, N.1    Facchinetti, F.2    Southworth, T.3
  • 37
    • 60549113990 scopus 로고    scopus 로고
    • Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK
    • Hui KP, Lee SM, Cheung CY et al. Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK. J Immunol 2009;182:1088-1098.
    • (2009) J Immunol , vol.182 , pp. 1088-1098
    • Hui, K.P.1    Lee, S.M.2    Cheung, C.Y.3
  • 38
    • 21544437592 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinases and NF-kappaB in the regulation of proinflammatory and anti-inflammatory cytokines by Porphyromonas gingivalis hemagglutinin B
    • Zhang P, Martin M, Michalek SM et al. Role of mitogen-activated protein kinases and NF-kappaB in the regulation of proinflammatory and anti-inflammatory cytokines by Porphyromonas gingivalis hemagglutinin B. Infect Immun 2005;73:3990-3998.
    • (2005) Infect Immun , vol.73 , pp. 3990-3998
    • Zhang, P.1    Martin, M.2    Michalek, S.M.3
  • 39
    • 68949175351 scopus 로고    scopus 로고
    • P38 MAPK and MMP-9 cooperatively regulate mucus overproduction in mice exposed to acrolein fog
    • Liu DS, Wang T, Han SX et al. p38 MAPK and MMP-9 cooperatively regulate mucus overproduction in mice exposed to acrolein fog. Int Immunopharmacol 2009;9:1228-1235.
    • (2009) Int Immunopharmacol , vol.9 , pp. 1228-1235
    • Liu, D.S.1    Wang, T.2    Han, S.X.3
  • 40
    • 84900846903 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase determines the susceptibility to cigarette smoke-induced emphysema in mice
    • Marumo S, Hoshino Y, Kiyokawa H et al. p38 mitogen-activated protein kinase determines the susceptibility to cigarette smoke-induced emphysema in mice. BMC Pulm Med 2014;14:79.
    • (2014) BMC Pulm Med , vol.14 , pp. 79
    • Marumo, S.1    Hoshino, Y.2    Kiyokawa, H.3
  • 41
    • 0033136947 scopus 로고    scopus 로고
    • The role of p38 mitogen-activated protein kinase in IL-1 beta transcription
    • Baldassare JJ, Bi Y, Bellone CJ. The role of p38 mitogen-activated protein kinase in IL-1 beta transcription. J Immunol 1999;162: 5367-5373.
    • (1999) J Immunol , vol.162 , pp. 5367-5373
    • Baldassare, J.J.1    Bi, Y.2    Bellone, C.J.3
  • 42
    • 70350316759 scopus 로고    scopus 로고
    • Prolonged cigarette smoke exposure decreases heme oxygenase-1 and alters Nrf2 and Bach1 expression in human macrophages: Roles of the MAP kinases ERK(1/2) and JNK
    • Goven D, Boutten A, Lecon-Malas V et al. Prolonged cigarette smoke exposure decreases heme oxygenase-1 and alters Nrf2 and Bach1 expression in human macrophages: roles of the MAP kinases ERK(1/2) and JNK. FEBS Lett 2009;583:3508-3518.
    • (2009) FEBS Lett , vol.583 , pp. 3508-3518
    • Goven, D.1    Boutten, A.2    Lecon-Malas, V.3
  • 43
    • 49049112707 scopus 로고    scopus 로고
    • Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide
    • Petrache I, Medler TR, Richter AT et al. Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide. Am J Physiol Lung Cell Mol Physiol 2008;295:L44-L53.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.295 , pp. L44-L53
    • Petrache, I.1    Medler, T.R.2    Richter, A.T.3
  • 44
    • 20444381360 scopus 로고    scopus 로고
    • Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: Protection against reactive oxygen and nitrogen species-induced cell injury
    • Zhu H, Itoh K, Yamamoto M et al. Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: protection against reactive oxygen and nitrogen species-induced cell injury. FEBS Lett 2005;579:3029-3036.
    • (2005) FEBS Lett , vol.579 , pp. 3029-3036
    • Zhu, H.1    Itoh, K.2    Yamamoto, M.3
  • 45
    • 33750620057 scopus 로고    scopus 로고
    • Oxidative stress and redox regulation of lung inflammation in COPD
    • Rahman I, Adcock IM. Oxidative stress and redox regulation of lung inflammation in COPD. Eur Respir J 2006;28:219-242.
    • (2006) Eur Respir J , vol.28 , pp. 219-242
    • Rahman, I.1    Adcock, I.M.2
  • 46
    • 34848814178 scopus 로고    scopus 로고
    • Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor-to forkhead box O-mediated transcription
    • Almeida M, Han L, Martin-Millan M et al. Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor-to forkhead box O-mediated transcription. J Biol Chem 2007;282:27298-27305.
    • (2007) J Biol Chem , vol.282 , pp. 27298-27305
    • Almeida, M.1    Han, L.2    Martin-Millan, M.3
  • 47
    • 84877742072 scopus 로고    scopus 로고
    • Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade
    • Vanella L, Sodhi K, Kim DH et al. Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade. Stem Cell Res Ther 2013;4:28.
    • (2013) Stem Cell Res Ther , vol.4 , pp. 28
    • Vanella, L.1    Sodhi, K.2    Kim, D.H.3
  • 48
    • 84874454971 scopus 로고    scopus 로고
    • β-Catenin regulates innate and adaptive immunity in mouse liver ischemia-reperfusion injury
    • Ke B, Shen XD, Kamo N et al. β-Catenin regulates innate and adaptive immunity in mouse liver ischemia-reperfusion injury. Hepatology 2013;57:1203-1214.
    • (2013) Hepatology , vol.57 , pp. 1203-1214
    • Ke, B.1    Shen, X.D.2    Kamo, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.