메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Heme oxygenase-1 is dispensable for the anti-inflammatory activity of intravenous immunoglobulin

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; HEME OXYGENASE 1; IMMUNOGLOBULIN; PROTECTIVE AGENT;

EID: 84955515806     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep19592     Document Type: Article
Times cited : (20)

References (60)
  • 1
    • 70249103810 scopus 로고    scopus 로고
    • Intravenous immunoglobulin therapy for autoimmune diseases
    • Arnson, Y., Shoenfeld, Y. & Amital, H. Intravenous immunoglobulin therapy for autoimmune diseases. Autoimmunity 42, 553-560 (2009).
    • (2009) Autoimmunity , vol.42 , pp. 553-560
    • Arnson, Y.1    Shoenfeld, Y.2    Amital, H.3
  • 2
    • 79958140473 scopus 로고    scopus 로고
    • Intravenous immunoglobulin therapy in rheumatic diseases
    • Bayry, J., Negi, V. S. & Kaveri, S. V. Intravenous immunoglobulin therapy in rheumatic diseases. Nat. Rev. Rheumatol. 7, 349-359 (2011).
    • (2011) Nat. Rev. Rheumatol. , vol.7 , pp. 349-359
    • Bayry, J.1    Negi, V.S.2    Kaveri, S.V.3
  • 3
    • 84926160722 scopus 로고    scopus 로고
    • Intravenous immunoglobulin in neurology-mode of action and clinical efficacy
    • Lunemann, J. D., Nimmerjahn, F. & Dalakas, M. C. Intravenous immunoglobulin in neurology-mode of action and clinical efficacy. Nat. Rev. Neurol. 11, 80-89 (2015).
    • (2015) Nat. Rev. Neurol. , vol.11 , pp. 80-89
    • Lunemann, J.D.1    Nimmerjahn, F.2    Dalakas, M.C.3
  • 4
    • 84930757874 scopus 로고    scopus 로고
    • Kawasaki disease: An evolving paradigm
    • Greco, A. et al. Kawasaki disease: an evolving paradigm. Autoimmun. Rev. 14, 703-709 (2015).
    • (2015) Autoimmun. Rev. , vol.14 , pp. 703-709
    • Greco, A.1
  • 5
    • 84881164768 scopus 로고    scopus 로고
    • Polyclonal immunoglobulin G for autoimmune demyelinating nervous system disorders
    • Buttmann, M., Kaveri, S. & Hartung, H. P. Polyclonal immunoglobulin G for autoimmune demyelinating nervous system disorders. Trends Pharmacol. Sci. 34, 445-457 (2013).
    • (2013) Trends Pharmacol. Sci. , vol.34 , pp. 445-457
    • Buttmann, M.1    Kaveri, S.2    Hartung, H.P.3
  • 6
    • 79551488012 scopus 로고    scopus 로고
    • The IgG molecule as a biological immune response modifier: Mechanisms of action of intravenous immune serum globulin in autoimmune and inflammatory disorders
    • Ballow, M. The IgG molecule as a biological immune response modifier: mechanisms of action of intravenous immune serum globulin in autoimmune and inflammatory disorders. J. Allergy Clin. Immunol. 127, 315-323(2011).
    • (2011) J. Allergy Clin. Immunol. , vol.127 , pp. 315-323
    • Ballow, M.1
  • 9
    • 84869431305 scopus 로고    scopus 로고
    • Intravenous immune globulin in autoimmune and inflammatory diseases
    • Gelfand, E. W. Intravenous immune globulin in autoimmune and inflammatory diseases. N. Engl. J. Med. 367, 2015-25 (2012).
    • (2012) N. Engl. J. Med. , vol.367 , pp. 2015-2025
    • Gelfand, E.W.1
  • 10
    • 84908189418 scopus 로고    scopus 로고
    • Subcutaneous IgG in immune-mediate diseases: Proposed mechanisms of action and literature review
    • Danieli, M. G. et al. Subcutaneous IgG in immune-mediate diseases: proposed mechanisms of action and literature review. Autoimmun. Rev. 13, 1182-1188 (2014).
    • (2014) Autoimmun. Rev. , vol.13 , pp. 1182-1188
    • Danieli, M.G.1
  • 11
    • 58149378347 scopus 로고    scopus 로고
    • Identification of a receptor required for the anti-inflammatory activity of IVIG
    • Anthony, R. M., Wermeling, F., Karlsson, M. C. & Ravetch, J. V. Identification of a receptor required for the anti-inflammatory activity of IVIG. Proc. Natl. Acad. Sci. USA 105, 19571-19578 (2008).
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 19571-19578
    • Anthony, R.M.1    Wermeling, F.2    Karlsson, M.C.3    Ravetch, J.V.4
  • 12
    • 33845976292 scopus 로고    scopus 로고
    • A role for IL-1 receptor antagonist or other cytokines in the acute therapeutic effects of IVIg?
    • Crow, A. R., Song, S., Semple, J. W., Freedman, J. & Lazarus, A. H. A role for IL-1 receptor antagonist or other cytokines in the acute therapeutic effects of IVIg? Blood 109, 155-158 (2007).
    • (2007) Blood , vol.109 , pp. 155-158
    • Crow, A.R.1    Song, S.2    Semple, J.W.3    Freedman, J.4    Lazarus, A.H.5
  • 13
    • 84891735723 scopus 로고    scopus 로고
    • Intravenous immunoglobulin induces a functional silencing program similar to anergy in human B cells
    • Seite, J. F., Goutsmedt, C., Youinou, P., Pers, J. O. & Hillion, S. Intravenous immunoglobulin induces a functional silencing program similar to anergy in human B cells. J. Allergy Clin. Immunol. 133, 181-188 (2014).
    • (2014) J. Allergy Clin. Immunol. , vol.133 , pp. 181-188
    • Seite, J.F.1    Goutsmedt, C.2    Youinou, P.3    Pers, J.O.4    Hillion, S.5
  • 14
    • 67651027514 scopus 로고    scopus 로고
    • Intravenous immunoglobulin a natural regulator of immunity and inflammation
    • Jordan, S. C., Toyoda, M. & Vo, A. A. Intravenous immunoglobulin a natural regulator of immunity and inflammation. Transplantation 88, 1-6 (2009).
    • (2009) Transplantation , vol.88 , pp. 1-6
    • Jordan, S.C.1    Toyoda, M.2    Vo, A.A.3
  • 15
    • 84875410765 scopus 로고    scopus 로고
    • Intravenous immunoglobulin therapy: How does IgG modulate the immune system?
    • Schwab, I. & Nimmerjahn, F. Intravenous immunoglobulin therapy: how does IgG modulate the immune system? Nat. Rev. Immunol. 13, 176-189 (2013).
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 176-189
    • Schwab, I.1    Nimmerjahn, F.2
  • 16
    • 84904295493 scopus 로고    scopus 로고
    • Intravenous immunoglobulin-induced IL-33 is insufficient to mediate basophil expansion in autoimmune patients
    • Sharma, M. et al. Intravenous immunoglobulin-induced IL-33 is insufficient to mediate basophil expansion in autoimmune patients. Sci. Rep. 4, 5672, doi: 10.1038/srep05672 (2014).
    • (2014) Sci. Rep. , vol.4 , pp. 5672
    • Sharma, M.1
  • 17
    • 84901251341 scopus 로고    scopus 로고
    • Therapeutic effect of IVIG on inflammatory arthritis in mice is dependent on the Fc portion and independent of sialylation or basophils
    • Campbell, I. K. et al. Therapeutic effect of IVIG on inflammatory arthritis in mice is dependent on the Fc portion and independent of sialylation or basophils. J. Immunol. 192, 5031-5038 (2014).
    • (2014) J. Immunol. , vol.192 , pp. 5031-5038
    • Campbell, I.K.1
  • 18
    • 77956184713 scopus 로고    scopus 로고
    • Immunomodulation by intravenous immunoglobulin: Role of regulatory T cells
    • Maddur, M. S. et al. Immunomodulation by intravenous immunoglobulin: role of regulatory T cells. J. Clin. Immunol. 30 (Suppl 1), S4-S8 (2010).
    • (2010) J. Clin. Immunol. , vol.30 , pp. S4-S8
    • Maddur, M.S.1
  • 19
    • 84872403415 scopus 로고    scopus 로고
    • Tregitope update: Mechanism of action parallels IVIg
    • Cousens, L. P. et al. Tregitope update: mechanism of action parallels IVIg. Autoimmun. Rev. 12, 436-443 (2013).
    • (2013) Autoimmun. Rev. , vol.12 , pp. 436-443
    • Cousens, L.P.1
  • 20
    • 84919723220 scopus 로고    scopus 로고
    • Inhibition of FcgammaR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcgammaRIIb in human macrophages
    • Nagelkerke, S. Q. et al. Inhibition of FcgammaR-mediated phagocytosis by IVIg is independent of IgG-Fc sialylation and FcgammaRIIb in human macrophages. Blood 124, 3709-3718 (2014).
    • (2014) Blood , vol.124 , pp. 3709-3718
    • Nagelkerke, S.Q.1
  • 21
    • 84924609109 scopus 로고    scopus 로고
    • Molecular and immunological biomarkers to predict IVIg response
    • Galeotti, C., Kaveri, S. V. & Bayry, J. Molecular and immunological biomarkers to predict IVIg response. Trends Mol. Med. 21, 145-147 (2015).
    • (2015) Trends Mol. Med. , vol.21 , pp. 145-147
    • Galeotti, C.1    Kaveri, S.V.2    Bayry, J.3
  • 22
    • 41149177025 scopus 로고    scopus 로고
    • Pharmacological and clinical aspects of heme oxygenase
    • Abraham, N. G. & Kappas, A. Pharmacological and clinical aspects of heme oxygenase. Pharmacol. Rev. 60, 79-127 (2008).
    • (2008) Pharmacol. Rev. , vol.60 , pp. 79-127
    • Abraham, N.G.1    Kappas, A.2
  • 23
    • 33846819008 scopus 로고    scopus 로고
    • Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation
    • Chora, A. A. et al. Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation. J. Clin. Invest. 117, 438-447(2007).
    • (2007) J. Clin. Invest. , vol.117 , pp. 438-447
    • Chora, A.A.1
  • 24
    • 38149008232 scopus 로고    scopus 로고
    • Heme oxygenase-1-derived carbon monoxide enhances the host defense response to microbial sepsis in mice
    • Chung, S. W., Liu, X., Macias, A. A., Baron, R. M. & Perrella, M. A. Heme oxygenase-1-derived carbon monoxide enhances the host defense response to microbial sepsis in mice. J. Clin. Invest. 118, 239-247 (2008).
    • (2008) J. Clin. Invest. , vol.118 , pp. 239-247
    • Chung, S.W.1    Liu, X.2    Macias, A.A.3    Baron, R.M.4    Perrella, M.A.5
  • 25
    • 34248182498 scopus 로고    scopus 로고
    • Systemic expression of heme oxygenase-1 ameliorates type 1 diabetes in NOD mice
    • Hu, C. M., Lin, H. H., Chiang, M. T., Chang, P. F. & Chau, L. Y. Systemic expression of heme oxygenase-1 ameliorates type 1 diabetes in NOD mice. Diabetes 56, 1240-1247 (2007).
    • (2007) Diabetes , vol.56 , pp. 1240-1247
    • Hu, C.M.1    Lin, H.H.2    Chiang, M.T.3    Chang, P.F.4    Chau, L.Y.5
  • 26
    • 0030045835 scopus 로고    scopus 로고
    • Heme oxygenase: A novel target for the modulation of the inflammatory response
    • Willis, D., Moore, A. R., Frederick, R. & Willoughby, D. A. Heme oxygenase: a novel target for the modulation of the inflammatory response. Nat. Med. 2, 87-90 (1996).
    • (1996) Nat. Med. , vol.2 , pp. 87-90
    • Willis, D.1    Moore, A.R.2    Frederick, R.3    Willoughby, D.A.4
  • 27
    • 43049170080 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis senses host-derived carbon monoxide during macrophage infection
    • Shiloh, M. U., Manzanillo, P. & Cox, J. S. Mycobacterium tuberculosis senses host-derived carbon monoxide during macrophage infection. Cell Host Microbe 3, 323-330 (2008).
    • (2008) Cell Host Microbe , vol.3 , pp. 323-330
    • Shiloh, M.U.1    Manzanillo, P.2    Cox, J.S.3
  • 28
    • 1842529311 scopus 로고    scopus 로고
    • Carbon monoxide produced by heme oxygenase-1 suppresses T cell proliferation via inhibition of IL-2 production
    • Pae, H. O. et al. Carbon monoxide produced by heme oxygenase-1 suppresses T cell proliferation via inhibition of IL-2 production. J. Immunol. 172, 4744-4751 (2004).
    • (2004) J. Immunol. , vol.172 , pp. 4744-4751
    • Pae, H.O.1
  • 29
    • 0032893958 scopus 로고    scopus 로고
    • Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency
    • Yachie, A. et al. Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency. J. Clin. Invest. 103, 129-135 (1999).
    • (1999) J. Clin. Invest. , vol.103 , pp. 129-135
    • Yachie, A.1
  • 30
    • 38348998603 scopus 로고    scopus 로고
    • Heme oxygenase-1 attenuates ovalbumin-induced airway inflammation by up-regulation of foxp3 T-regulatory cells, interleukin-10, and membrane-bound transforming growth factor- 1
    • Xia, Z. W. et al. Heme oxygenase-1 attenuates ovalbumin-induced airway inflammation by up-regulation of foxp3 T-regulatory cells, interleukin-10, and membrane-bound transforming growth factor- 1. Am. J. Pathol. 171, 1904-1914 (2007).
    • (2007) Am. J. Pathol. , vol.171 , pp. 1904-1914
    • Xia, Z.W.1
  • 31
    • 33845901771 scopus 로고    scopus 로고
    • Heme oxygenase-1 is not required for mouse regulatory T cell development and function
    • Zelenay, S., Chora, A., Soares, M. P. & Demengeot, J. Heme oxygenase-1 is not required for mouse regulatory T cell development and function. Int. Immunol. 19, 11-18 (2007).
    • (2007) Int. Immunol. , vol.19 , pp. 11-18
    • Zelenay, S.1    Chora, A.2    Soares, M.P.3    Demengeot, J.4
  • 32
    • 0043268709 scopus 로고    scopus 로고
    • Heme oxygenase-1: Unleashing the protective properties of heme
    • Otterbein, L. E., Soares, M. P., Yamashita, K. & Bach, F. H. Heme oxygenase-1: unleashing the protective properties of heme. Trends Immunol. 24, 449-455 (2003).
    • (2003) Trends Immunol. , vol.24 , pp. 449-455
    • Otterbein, L.E.1    Soares, M.P.2    Yamashita, K.3    Bach, F.H.4
  • 33
    • 0034071424 scopus 로고    scopus 로고
    • Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway
    • Otterbein, L. E. et al. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat. Med. 6, 422-428 (2000).
    • (2000) Nat. Med. , vol.6 , pp. 422-428
    • Otterbein, L.E.1
  • 34
    • 58149181985 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced expression of NAD(P)H:quinone oxidoreductase 1 and heme oxygenase-1 protects against excessive inflammatory responses in human monocytes
    • Rushworth, S. A., MacEwan, D. J. & O'Connell, M. A. Lipopolysaccharide-induced expression of NAD(P)H:quinone oxidoreductase 1 and heme oxygenase-1 protects against excessive inflammatory responses in human monocytes. J. Immunol. 181, 6730-6737 (2008).
    • (2008) J. Immunol. , vol.181 , pp. 6730-6737
    • Rushworth, S.A.1    MacEwan, D.J.2    O'Connell, M.A.3
  • 35
    • 23944437926 scopus 로고    scopus 로고
    • Heme oxygenase-1 expression inhibits dendritic cell maturation and proinflammatory function but conserves IL-10 expression
    • Chauveau, C. et al. Heme oxygenase-1 expression inhibits dendritic cell maturation and proinflammatory function but conserves IL-10 expression. Blood 106, 1694-1702 (2005).
    • (2005) Blood , vol.106 , pp. 1694-1702
    • Chauveau, C.1
  • 36
    • 61449255986 scopus 로고    scopus 로고
    • Carbon monoxide inhibits TLR-induced dendritic cell immunogenicity
    • Remy, S. et al. Carbon monoxide inhibits TLR-induced dendritic cell immunogenicity. J. Immunol. 182, 1877-1884 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 1877-1884
    • Remy, S.1
  • 37
    • 0037438669 scopus 로고    scopus 로고
    • Inhibition of maturation and function of dendritic cells by intravenous immunoglobulin
    • Bayry, J. et al. Inhibition of maturation and function of dendritic cells by intravenous immunoglobulin. Blood 101, 758-765 (2003).
    • (2003) Blood , vol.101 , pp. 758-765
    • Bayry, J.1
  • 38
    • 84902179159 scopus 로고    scopus 로고
    • Intravenous immunoglobulin treatment in humans suppresses dendritic cell function via stimulation of IL-4 and IL-13 production
    • Tjon, A. S. et al. Intravenous immunoglobulin treatment in humans suppresses dendritic cell function via stimulation of IL-4 and IL-13 production. J. Immunol. 192, 5625-5634 (2014).
    • (2014) J. Immunol. , vol.192 , pp. 5625-5634
    • Tjon, A.S.1
  • 39
    • 84904017104 scopus 로고    scopus 로고
    • Induction of PD-L1 on monocytes: A new mechanism by which IVIg inhibits mixed lymphocyte reactions
    • Padet, L., Loubaki, L. & Bazin, R. Induction of PD-L1 on monocytes: a new mechanism by which IVIg inhibits mixed lymphocyte reactions. Immunobiology 219, 687-694 (2014).
    • (2014) Immunobiology , vol.219 , pp. 687-694
    • Padet, L.1    Loubaki, L.2    Bazin, R.3
  • 40
    • 84886806068 scopus 로고    scopus 로고
    • Intravenous immunoglobulin expands regulatory T cells via induction of cyclooxygenase-2-dependent prostaglandin E2 in human dendritic cells
    • Trinath, J. et al. Intravenous immunoglobulin expands regulatory T cells via induction of cyclooxygenase-2-dependent prostaglandin E2 in human dendritic cells. Blood 122, 1419-1427 (2013).
    • (2013) Blood , vol.122 , pp. 1419-1427
    • Trinath, J.1
  • 41
    • 84876783124 scopus 로고    scopus 로고
    • Intravenous gammaglobulin inhibits encephalitogenic potential of pathogenic T cells and interferes with their trafficking to the central nervous system, implicating sphingosine-1 phosphate receptor 1-mammalian target of rapamycin axis
    • Othy, S. et al. Intravenous gammaglobulin inhibits encephalitogenic potential of pathogenic T cells and interferes with their trafficking to the central nervous system, implicating sphingosine-1 phosphate receptor 1-mammalian target of rapamycin axis. J. Immunol. 190, 4535-4541 (2013).
    • (2013) J. Immunol. , vol.190 , pp. 4535-4541
    • Othy, S.1
  • 42
    • 84928963187 scopus 로고    scopus 로고
    • Protection in antibody- and T cell-mediated autoimmune diseases by antiinflammatory IgG Fcs requires type II FcRs
    • Fiebiger, B. M., Maamary, J., Pincetic, A. & Ravetch, J. V. Protection in antibody- and T cell-mediated autoimmune diseases by antiinflammatory IgG Fcs requires type II FcRs. Proc. Natl. Acad. Sci. USA 112, E2385-E2394 (2015).
    • (2015) Proc. Natl. Acad. Sci. USA , vol.112 , pp. E2385-E2394
    • Fiebiger, B.M.1    Maamary, J.2    Pincetic, A.3    Ravetch, J.V.4
  • 43
    • 79952313700 scopus 로고    scopus 로고
    • Inhibition of differentiation, amplification, and function of human TH17 cells by intravenous immunoglobulin
    • Maddur, M. S. et al. Inhibition of differentiation, amplification, and function of human TH17 cells by intravenous immunoglobulin. J. Allergy Clin. Immunol. 127, 823-830 (2011).
    • (2011) J. Allergy Clin. Immunol. , vol.127 , pp. 823-830
    • Maddur, M.S.1
  • 44
    • 84872615386 scopus 로고    scopus 로고
    • Inhibitory effect of IVIG on IL-17 production by Th17 cells is independent of anti-IL-17 antibodies in the immunoglobulin preparations
    • Maddur, M. S. et al. Inhibitory effect of IVIG on IL-17 production by Th17 cells is independent of anti-IL-17 antibodies in the immunoglobulin preparations. J. Clin. Immunol. 33, S62-S66 (2013).
    • (2013) J. Clin. Immunol. , vol.33 , pp. S62-S66
    • Maddur, M.S.1
  • 45
    • 84941105906 scopus 로고    scopus 로고
    • Intravenous immunoglobulin-mediated expansion of regulatory T cells in autoimmune patients is associated with increased prostaglandin E2 levels in the circulation
    • Maddur, M. S. et al. Intravenous immunoglobulin-mediated expansion of regulatory T cells in autoimmune patients is associated with increased prostaglandin E2 levels in the circulation. Cell. Mol. Immunol. 12, 650-652 (2015).
    • (2015) Cell. Mol. Immunol. , vol.12 , pp. 650-652
    • Maddur, M.S.1
  • 46
    • 38349137792 scopus 로고    scopus 로고
    • Intravenous immunoglobulin therapy affects T regulatory cells by increasing their suppressive function
    • Kessel, A. et al. Intravenous immunoglobulin therapy affects T regulatory cells by increasing their suppressive function. J. Immunol. 179, 5571-5575(2007).
    • (2007) J. Immunol. , vol.179 , pp. 5571-5575
    • Kessel, A.1
  • 47
    • 84856531046 scopus 로고    scopus 로고
    • Intravenous immunoglobulin expands regulatory T cells in autoimmune rheumatic disease
    • Bayry, J., Mouthon, L. & Kaveri S. V. Intravenous immunoglobulin expands regulatory T cells in autoimmune rheumatic disease. J. Rheumatol. 39, 450-451 (2012).
    • (2012) J. Rheumatol. , vol.39 , pp. 450-451
    • Bayry, J.1    Mouthon, L.2    Kaveri, S.V.3
  • 48
    • 84896692591 scopus 로고    scopus 로고
    • Dendritic cell immunoreceptor: A novel receptor for intravenous immunoglobulin mediates induction of regulatory T cells
    • Massoud, A. H. et al. Dendritic cell immunoreceptor: a novel receptor for intravenous immunoglobulin mediates induction of regulatory T cells. J. Allergy Clin. Immunol. 133, 853-863 (2014).
    • (2014) J. Allergy Clin. Immunol. , vol.133 , pp. 853-863
    • Massoud, A.H.1
  • 49
    • 0037448802 scopus 로고    scopus 로고
    • Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: Implications in the antiproliferative response to rapamycin
    • Visner, G. A. et al. Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response to rapamycin. Circulation 107, 911-916 (2003).
    • (2003) Circulation , vol.107 , pp. 911-916
    • Visner, G.A.1
  • 50
    • 33749322644 scopus 로고    scopus 로고
    • Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts
    • Nakahira, K. et al. Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts. J. Exp. Med. 203, 2377-2389 (2006).
    • (2006) J. Exp. Med. , vol.203 , pp. 2377-2389
    • Nakahira, K.1
  • 53
    • 76149093518 scopus 로고    scopus 로고
    • Pivotal advance: Heme oxygenase 1 expression by human CD4+ T cells is not sufficient for their development of immunoregulatory capacity
    • Biburger, M., Theiner, G., Schadle, M., Schuler, G. & Tiegs, G. Pivotal Advance: Heme oxygenase 1 expression by human CD4+ T cells is not sufficient for their development of immunoregulatory capacity. J. Leukoc. Biol. 87, 193-202 (2010).
    • (2010) J. Leukoc. Biol. , vol.87 , pp. 193-202
    • Biburger, M.1    Theiner, G.2    Schadle, M.3    Schuler, G.4    Tiegs, G.5
  • 54
    • 46749110831 scopus 로고    scopus 로고
    • Suppression by CD4+ CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigenpresenting cells
    • George, J. F. et al. Suppression by CD4+ CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigenpresenting cells. Am. J. Pathol. 173, 154-160 (2008).
    • (2008) Am. J. Pathol. , vol.173 , pp. 154-160
    • George, J.F.1
  • 55
    • 84889000385 scopus 로고    scopus 로고
    • Heme oxygenase-1 exerts a protective role in ovalbumin-induced neutrophilic airway inflammation by inhibiting Th17 cell-mediated immune response
    • Zhang, Y., Zhang, L., Wu, J., Di, C. & Xia, Z. Heme oxygenase-1 exerts a protective role in ovalbumin-induced neutrophilic airway inflammation by inhibiting Th17 cell-mediated immune response. J. Biol. Chem. 288, 34612-34626 (2013).
    • (2013) J. Biol. Chem. , vol.288 , pp. 34612-34626
    • Zhang, Y.1    Zhang, L.2    Wu, J.3    Di, C.4    Xia, Z.5
  • 56
    • 84879022405 scopus 로고    scopus 로고
    • Eye-mediated induction of specific immune tolerance to encephalitogenic antigens
    • Farooq, S. M. & Ashour, H. M. Eye-mediated induction of specific immune tolerance to encephalitogenic antigens. CNS Neurosci. Ther. 19, 503-510 (2013).
    • (2013) CNS Neurosci. Ther. , vol.19 , pp. 503-510
    • Farooq, S.M.1    Ashour, H.M.2
  • 57
    • 84893454390 scopus 로고    scopus 로고
    • The experimental autoimmune encephalomyelitis (EAE) model of MS: Utility for understanding disease pathophysiology and treatment
    • Robinson, A. P., Harp, C. T., Noronha, A. & Miller, S. D. The experimental autoimmune encephalomyelitis (EAE) model of MS: utility for understanding disease pathophysiology and treatment. Handb. Clin. Neurol. 122, 173-189 (2014).
    • (2014) Handb. Clin. Neurol. , vol.122 , pp. 173-189
    • Robinson, A.P.1    Harp, C.T.2    Noronha, A.3    Miller, S.D.4
  • 58
    • 84932194321 scopus 로고    scopus 로고
    • IVIg for relapsing-remitting multiple sclerosis: Promises and uncertainties
    • Bayry, J., Hartung, H. P. & Kaveri, S. V. IVIg for relapsing-remitting multiple sclerosis: promises and uncertainties. Trends Pharmacol. Sci. 36, 419-421 (2015).
    • (2015) Trends Pharmacol. Sci. , vol.36 , pp. 419-421
    • Bayry, J.1    Hartung, H.P.2    Kaveri, S.V.3
  • 59
    • 80053231181 scopus 로고    scopus 로고
    • Comparison of different IVIg preparations on IL-17 production by human Th17 cells
    • Maddur, M. S., Kaveri, S. V. & Bayry, J. Comparison of different IVIg preparations on IL-17 production by human Th17 cells. Autoimmun. Rev. 10, 809-810 (2011).
    • (2011) Autoimmun. Rev. , vol.10 , pp. 809-810
    • Maddur, M.S.1    Kaveri, S.V.2    Bayry, J.3
  • 60
    • 84902280163 scopus 로고    scopus 로고
    • Human B cells induce dendritic cell maturation and favour Th2 polarization by inducing OX-40 ligand
    • Maddur, M. S. et al. Human B cells induce dendritic cell maturation and favour Th2 polarization by inducing OX-40 ligand. Nat. Commun. 5, 4092, doi: 10.1038/ncomms5092 (2014).
    • (2014) Nat. Commun. , vol.5 , pp. 4092
    • Maddur, M.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.