Functional interplay between ganglioside GM1 and cross-linking galectin-1 induces axon-like neuritogenesis via integrin-based signaling and TRPC5-dependent Ca2+ influx

Journal of Neurochemistry

Volumn 136, Issue 3, 2016, Pages 550-563

  Wu, Gusheng ^a   Lu, Zi Hua ^a   André, Sabine ^b   Gabius, Hans Joachim ^b   Ledeen, Robert W ^a  

^a RUTGERS UNIVERSITY   (United States)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

axon growth; Ca2+ level; ganglioside; integrin; lectin; neuron

Indexed keywords

1-NITROHYDROXYPHENYL-N-BENZOYLALANINE; BENZAMIDE DERIVATIVE; CALCIUM; ENZYME INHIBITOR; GALECTIN 1; GANGLIOSIDE GM1; INTEGRIN; PROTEIN BINDING; SMALL INTERFERING RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; TRPC5 PROTEIN, HUMAN; TYROSINE;

ANALOGS AND DERIVATIVES; ANIMAL; AXON; C57BL MOUSE; CELL CULTURE; CEREBELLUM; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOUSE; NEWBORN; PHYSIOLOGY; RAT; SIGNAL TRANSDUCTION; TEMPERATURE;

ANIMALS; ANIMALS, NEWBORN; AXONS; BENZAMIDES; CALCIUM; CELLS, CULTURED; CEREBELLUM; ENZYME INHIBITORS; G(M1) GANGLIOSIDE; GALECTIN 1; GENE EXPRESSION REGULATION; INTEGRINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN BINDING; RATS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TEMPERATURE; TRPC CATION CHANNELS; TYROSINE;

EID: 84955407405     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13418     Document Type: Article

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