Kava for the treatment of generalised anxiety disorder (K-GAD): Study protocol for a randomised controlled trial

Trials

Volumn 16, Issue 1, 2015, Pages

  Savage, Karen M ^a,b   Stough, Con K ^b   Byrne, Gerard J ^c   Scholey, Andrew ^b   Bousman, Chad ^a,b   Murphy, Jenifer ^a   Macdonald, Patricia ^c   Suo, Chao ^d   Hughes, Matthew ^b   Thomas, Stuart ^d   Teschke, Rolf ^e   Xing, Chengguo ^f   Sarris, Jerome ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b SWINBURNE UNIVERSITY OF TECHNOLOGY   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d MONASH UNIVERSITY   (Australia)

^e UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^f UNIVERSITY OF MINNESOTA DULUTH   (United States)

Author keywords

Anxiety; Anxiolytic; GABA; GAD; Kava; Kavalactones; Nutraceutical; Protocol; RCT

Indexed keywords

4 AMINOBUTYRIC ACID CARRIER; GLUTAMIC ACID; GLUTAMINE; KAVA; PLACEBO; ANXIOLYTIC AGENT; PLANT EXTRACT;

ADULT; AFFECT; AGED; ANTERIOR CINGULATE; ANXIETY ASSESSMENT; AQUEOUS SOLUTION; ARTICLE; AUSTRALIA; BECK ANXIETY INVENTORY; BRAIN METABOLISM; CONTROLLED STUDY; CORRELATION ANALYSIS; CULTIVAR; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG STRUCTURE; FEMALE; FINANCIAL MANAGEMENT; GENE EXPRESSION; GENERALIZED ANXIETY DISORDER; HUMAN; INFORMED CONSENT; KESSLER PSYCHOLOGICAL DISTRESS SCALE; MAJOR CLINICAL STUDY; MALE; MEDICINAL PLANT; METHODOLOGY; MONTGOMERY ASBERG DEPRESSION RATING SCALE; MULTICENTER STUDY; NEUROBIOLOGY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PENN STATE WORRY QUESTIONNAIRE; PHARMACOGENOMICS; PHASE 3 CLINICAL TRIAL; PIPER METHYSTICUM; QUALITY OF LIFE; QUALITY OF LIFE ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; SEXUAL SATISFACTION; SOCIAL READJUSTMENT RATING SCALE; STRUCTURED INTERVIEW GUIDE FOR THE HAMILTON ANXIETY RATING SCALE; TRANQUILIZING ACTIVITY; TREATMENT OUTCOME; TREATMENT RESPONSE; ADOLESCENT; ANXIETY DISORDERS; BRAIN; CHEMISTRY; CLINICAL PROTOCOL; CLINICAL TRIAL; DRUG EFFECTS; FUNCTIONAL NEUROIMAGING; GENETIC POLYMORPHISM; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PHARMACOGENETICS; PHYTOTHERAPY; PLANT ROOT; PSYCHOLOGICAL RATING SCALE; PSYCHOLOGY; QUEENSLAND; QUESTIONNAIRE; REGISTER; TIME FACTOR; VICTORIA; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANTI-ANXIETY AGENTS; ANXIETY DISORDERS; BRAIN; CLINICAL PROTOCOLS; DOUBLE-BLIND METHOD; FEMALE; FUNCTIONAL NEUROIMAGING; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; HUMANS; KAVA; MALE; MIDDLE AGED; PHARMACOGENETICS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; PLANTS, MEDICINAL; POLYMORPHISM, GENETIC; PSYCHIATRIC STATUS RATING SCALES; QUEENSLAND; REGISTRIES; RESEARCH DESIGN; SURVEYS AND QUESTIONNAIRES; TIME FACTORS; TREATMENT OUTCOME; VICTORIA; YOUNG ADULT;

EID: 84955335190     PISSN: None     EISSN: 17456215     Source Type: Journal    
DOI: 10.1186/s13063-015-0986-5     Document Type: Article

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