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Volumn 2, Issue , 2010, Pages 453-467

Pharmacological treatment of generalized anxiety disorder

Author keywords

GAD; Pregabalin; SNRI; SSRI; Treatment

Indexed keywords

ALPRAZOLAM; BENZODIAZEPINE DERIVATIVE; DULOXETINE; ESCITALOPRAM; LORAZEPAM; PAROXETINE; PLACEBO; PREGABALIN; QUETIAPINE; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; VENLAFAXINE; ADRENERGIC RECEPTOR AFFECTING AGENT; ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT;

EID: 79952269149     PISSN: 18663370     EISSN: 18663389     Source Type: Book Series    
DOI: 10.1007/7854_2009_2     Document Type: Article
Times cited : (30)

References (93)
  • 2
    • 0034931866 scopus 로고    scopus 로고
    • Venlafaxine extended release (ER) in the treatment of generalised anxiety disorder: Twenty-four-week placebo-controlled dose-ranging study
    • Allgulander C, Hackett D, Salinas E (2001) Venlafaxine extended release (ER) in the treatment of generalised anxiety disorder: twenty-four-week placebo-controlled dose-ranging study. Br J Psychiatry 179:15-22
    • (2001) Br J Psychiatry , vol.179 , pp. 15-22
    • Allgulander, C.1    Hackett, D.2    Salinas, E.3
  • 3
    • 4444345940 scopus 로고    scopus 로고
    • Efficacy of sertraline in a 12-week trial for generalized anxiety disorder
    • Allgulander C, Dahl AA, Austin C et al (2004) Efficacy of sertraline in a 12-week trial for generalized anxiety disorder. Am J Psychiatry 161: 1642-1649
    • (2004) Am J Psychiatry , vol.161 , pp. 1642-1649
    • Allgulander, C.1    Dahl, A.A.2    Austin, C.3
  • 4
    • 33750217338 scopus 로고    scopus 로고
    • Prevention of relapse in generalized anxiety disorder by escitalopram treatment
    • Allgulander C, Florea I, Huusom AK (2006) Prevention of relapse in generalized anxiety disorder by escitalopram treatment. Int J Neuropsychopharmacol 9:495-505
    • (2006) Int J Neuropsychopharmacol , vol.9 , pp. 495-505
    • Allgulander, C.1    Florea, I.2    Huusom, A.K.3
  • 5
    • 65349153684 scopus 로고    scopus 로고
    • The generalized anxiety spectrum: Prevalence, onset, course and outcome
    • Angst J, Gamma A, Baldwin DS et al (2009) The generalized anxiety spectrum: prevalence, onset, course and outcome. Eur Arch Psychiatry Clin Neurosci 259: 37-45
    • (2009) Eur Arch Psychiatry Clin Neurosci , vol.259 , pp. 37-45
    • Angst, J.1    Gamma, A.2    Baldwin, D.S.3
  • 6
    • 4544274763 scopus 로고    scopus 로고
    • Sexual dysfunction associated with antidepressant drugs
    • Baldwin DS (2004) Sexual dysfunction associated with antidepressant drugs. Exp Opin Drug Safety 3:457-470
    • (2004) Exp Opin Drug Safety , vol.3 , pp. 457-470
    • Baldwin, D.S.1
  • 7
    • 34249893069 scopus 로고    scopus 로고
    • The role of pregabalin in the treatment of generalized anxiety disorder
    • Baldwin DS, Ajel K (2007) The role of pregabalin in the treatment of generalized anxiety disorder. Neuropsychiatric Dis Treat 3:185-191
    • (2007) Neuropsychiatric Dis Treat , vol.3 , pp. 185-191
    • Baldwin, D.S.1    Ajel, K.2
  • 8
    • 20044384075 scopus 로고    scopus 로고
    • Evidence-based pharmacotherapy of generalized anxiety disorder
    • Baldwin DS, Polkinghorn C (2005) Evidence-based pharmacotherapy of generalized anxiety disorder. Int J Neuropsychopharmacol 8:293-302
    • (2005) Int J Neuropsychopharmacol , vol.8 , pp. 293-302
    • Baldwin, D.S.1    Polkinghorn, C.2
  • 9
    • 27644534854 scopus 로고    scopus 로고
    • Evidence-based guidelines for the pharmacological treatment of anxiety disorders: Recommendations from the British association for Psychopharmacology
    • Baldwin DS, Anderson IM, Nutt DJ et al (2005) Evidence-based guidelines for the pharmacological treatment of anxiety disorders: recommendations from the British association for Psychopharmacology. J Psychopharmacol 19:567-596
    • (2005) J Psychopharmacol , vol.19 , pp. 567-596
    • Baldwin, D.S.1    Anderson, I.M.2    Nutt, D.J.3
  • 10
    • 33748432736 scopus 로고    scopus 로고
    • Escitalopram and paroxetine in the treatment of generalised anxiety disorder. Randomised, double-blind, placebo-controlled study
    • Baldwin DS, Huusom AKT, Maehlum E (2006a) Escitalopram and paroxetine in the treatment of generalised anxiety disorder. Randomised, double-blind, placebo-controlled study. Br J Psychiatry 189:264-272
    • (2006) Br J Psychiatry , vol.189 , pp. 264-272
    • Baldwin, D.S.1    Huusom, A.K.T.2    Maehlum, E.3
  • 11
    • 33645243454 scopus 로고    scopus 로고
    • Resolution of sexual dysfunction during double-blind treatment of major depression with reboxetine or paroxetine
    • Baldwin DS, Bridgman K, Buis C (2006b) Resolution of sexual dysfunction during double-blind treatment of major depression with reboxetine or paroxetine. J Psychopharmacol 20:91-96
    • (2006) J Psychopharmacol , vol.20 , pp. 91-96
    • Baldwin, D.S.1    Bridgman, K.2    Buis, C.3
  • 12
    • 34748874714 scopus 로고    scopus 로고
    • Escitalopram therapy for major depression and anxiety disorders
    • Baldwin DS, Reines EH, Guiton C et al (2007a) Escitalopram therapy for major depression and anxiety disorders. Ann Pharmacother 41:1583-1592
    • (2007) Ann Pharmacother , vol.41 , pp. 1583-1592
    • Baldwin, D.S.1    Reines, E.H.2    Guiton, C.3
  • 13
  • 14
    • 68049124865 scopus 로고    scopus 로고
    • How long should an initial treatment period be in patients with major depressive disorder, generalised anxiety disorder or social anxiety disorder? An exploration of the randomised controlled trial database
    • Baldwin DS, Stein DJ, Dolberg O et al (2009) How long should an initial treatment period be in patients with major depressive disorder, generalised anxiety disorder or social anxiety disorder? An exploration of the randomised controlled trial database. Hum Psychopharmacol 24:269-275
    • (2009) Hum Psychopharmacol , vol.24 , pp. 269-275
    • Baldwin, D.S.1    Stein, D.J.2    Dolberg, O.3
  • 15
    • 51049117224 scopus 로고    scopus 로고
    • Resolution of sexual dysfunction during acute treatment of major depression with milnacipran
    • Baldwin DS, Moreno R, Briley M (2008) Resolution of sexual dysfunction during acute treatment of major depression with milnacipran. Hum Psychopharmacol 23:527-532
    • (2008) Hum Psychopharmacol , vol.23 , pp. 527-532
    • Baldwin, D.S.1    Moreno, R.2    Briley, M.3
  • 16
    • 0033397229 scopus 로고    scopus 로고
    • Clinical guidelines for establishing remission in patients with depression and anxiety
    • Ballenger JC (1999) Clinical guidelines for establishing remission in patients with depression and anxiety. J Clin Psychiatry 60(suppl 22):29-34
    • (1999) J Clin Psychiatry , vol.60 , Issue.SUPPL. 22 , pp. 29-34
    • Ballenger, J.C.1
  • 17
    • 33746160520 scopus 로고    scopus 로고
    • What is the threshold for symptomatic response and remission for major depressive disorder, panic disorder, social anxiety disorder, and generalized anxiety disorder?
    • Bandelow B, Baldwin DS, Dolberg OT et al (2006) What is the threshold for symptomatic response and remission for major depressive disorder, panic disorder, social anxiety disorder, and generalized anxiety disorder? J Clin Psychiatry 67:1428-1434
    • (2006) J Clin Psychiatry , vol.67 , pp. 1428-1434
    • Bandelow, B.1    Baldwin, D.S.2    Dolberg, O.T.3
  • 18
    • 55449093251 scopus 로고    scopus 로고
    • Results from a phase III study of once-daily extended release quetiapine fumarate (quetiapine XR) monotherapy in patients with generalised anxiety disorder
    • (abstract)
    • Bandelow B, Bobes J, Ahokas A, et al (2007a) Results from a phase III study of once-daily extended release quetiapine fumarate (quetiapine XR) monotherapy in patients with generalised anxiety disorder. Int J Psychiatry Clin Pract 11:314-315 (abstract)
    • (2007) Int J Psychiatry Clin Pract , vol.11 , pp. 314-315
    • Bandelow, B.1    Bobes, J.2    Ahokas, A.3
  • 19
    • 34547467605 scopus 로고    scopus 로고
    • Meta-analysis of randomized controlled comparisons of psychopharmacological and psychological treatments for anxiety disorders
    • Bandelow B, Seidler-Brandler U, Becker A et al (2007b) Meta-analysis of randomized controlled comparisons of psychopharmacological and psychological treatments for anxiety disorders. World J Biol Psychiatr 8:175-187
    • (2007) World J Biol Psychiatr , vol.8 , pp. 175-187
    • Bandelow, B.1    Seidler-Brandler, U.2    Becker, A.3
  • 20
    • 34548781289 scopus 로고    scopus 로고
    • Dose-response relationship of pregabalin in patients with generalized anxiety disorder. A pooled analysis of four placebo-controlled trials
    • Bech P (2007) Dose-response relationship of pregabalin in patients with generalized anxiety disorder. A pooled analysis of four placebo-controlled trials. Pharmacopsychiatry 40:163-168
    • (2007) Pharmacopsychiatry , vol.40 , pp. 163-168
    • Bech, P.1
  • 21
    • 0031721919 scopus 로고    scopus 로고
    • Anxiety disorders in later life: A report from the longitudinal Aging Study Amsterdam
    • Beekman AT, Bremmer MA, Deeg DJ et al (1998) Anxiety disorders in later life: a report from the longitudinal Aging Study Amsterdam. Int J Geriatr Psychiatry 13:717-726
    • (1998) Int J Geriatr Psychiatry , vol.13 , pp. 717-726
    • Beekman, A.T.1    Bremmer, M.A.2    Deeg, D.J.3
  • 22
    • 27544471383 scopus 로고    scopus 로고
    • Adjunctive risperidone in generalized anxiety disorder: A double-blind, placebo-controlled study
    • Brawman-Mintzer O, Knapp RG, Nietert PJ (2005) Adjunctive risperidone in generalized anxiety disorder: a double-blind, placebo-controlled study. J Clin Psychiatry 66:1321-1325
    • (2005) J Clin Psychiatry , vol.66 , pp. 1321-1325
    • Brawman-Mintzer, O.1    Knapp, R.G.2    Nietert, P.J.3
  • 23
    • 33745877173 scopus 로고    scopus 로고
    • Sertraline treatment for generalized anxiety disorder: A randomized, double-blind, placebo-controlled study
    • Brawman-Mintzer O, Knapp RG, RynnMet al (2006) Sertraline treatment for generalized anxiety disorder: a randomized, double-blind, placebo-controlled study. J Clin Psychiatry 67:874-881
    • (2006) J Clin Psychiatry , vol.67 , pp. 874-881
    • Brawman-Mintzer, O.1    Knapp, R.G.2    Rynn, M.3
  • 24
    • 19644370282 scopus 로고    scopus 로고
    • Influence of psychiatric comorbidity on recovery and recurrence in generalized anxiety disorder, social phobia, and panic disorder: A 12-year prospective study
    • Bruce SE, Yonkers KA, Otto MW et al (2005) Influence of psychiatric comorbidity on recovery and recurrence in generalized anxiety disorder, social phobia, and panic disorder: a 12-year prospective study. Am J Psychiatry 162:1179-1187
    • (2005) Am J Psychiatry , vol.162 , pp. 1179-1187
    • Bruce, S.E.1    Yonkers, K.A.2    Otto, M.W.3
  • 25
    • 33749009561 scopus 로고    scopus 로고
    • Clinical practice guidelines. Management of anxiety disorders
    • Canadian Psychiatric Association
    • Canadian Psychiatric Association (2006) Clinical practice guidelines. Management of anxiety disorders. Can J Psychiatr 51:9S-91S
    • (2006) Can J Psychiatr , vol.51
  • 26
    • 33847664253 scopus 로고    scopus 로고
    • A comparison of rates of residual insomnia symptoms following pharmacotherapy or cognitive-behavioral therapy for major depressive disorder
    • Carney CE, Segal ZV, Edinger JD et al (2007) A comparison of rates of residual insomnia symptoms following pharmacotherapy or cognitive-behavioral therapy for major depressive disorder. J Clin Psychiatr 68:254-260
    • (2007) J Clin Psychiatr , vol.68 , pp. 254-260
    • Carney, C.E.1    Segal, Z.V.2    Edinger, J.D.3
  • 27
    • 13844296412 scopus 로고    scopus 로고
    • Sleep disturbances in patients treated for panic disorder
    • Cervena K, Matousek M, Prasko J et al (2005) Sleep disturbances in patients treated for panic disorder. Sleep Med 6:149-153
    • (2005) Sleep Med , vol.6 , pp. 149-153
    • Cervena, K.1    Matousek, M.2    Prasko, J.3
  • 29
    • 0032869591 scopus 로고    scopus 로고
    • Efficacy, safety, and tolerability of venlafaxine extended release and buspirone in outpatients with generalized anxiety disorder
    • Davidson JR, DuPont RL, Hedges D et al (1999) Efficacy, safety, and tolerability of venlafaxine extended release and buspirone in outpatients with generalized anxiety disorder. J Clin Psychiatry 60:528-535
    • (1999) J Clin Psychiatry , vol.60 , pp. 528-535
    • Davidson, J.R.1    DuPont, R.L.2    Hedges, D.3
  • 30
    • 3543042491 scopus 로고    scopus 로고
    • Escitalopram in the treatment of generalized anxiety disorder: Double-blind, placebo controlled, flexible-dose study
    • Davidson JR, Bose A, Korotzer A et al (2004) Escitalopram in the treatment of generalized anxiety disorder: double-blind, placebo controlled, flexible-dose study. Depress Anxiety 19:234-240
    • (2004) Depress Anxiety , vol.19 , pp. 234-240
    • Davidson, J.R.1    Bose, A.2    Korotzer, A.3
  • 31
    • 48849092703 scopus 로고    scopus 로고
    • Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: A double-blind placebo-controlled trial
    • Davidson JRT, Wittchen H.-U, Llorca P-M et al (2008) Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: a double-blind placebo-controlled trial. Eur Neuropsychopharmacol 18:673-681
    • (2008) Eur Neuropsychopharmacol , vol.18 , pp. 673-681
    • Davidson, J.R.T.1    Wittchen, H.-U.2    Llorca, P-M.3
  • 32
    • 0022405535 scopus 로고
    • Early treatment response in anxious outpatients treated with diazepam
    • Downing RW, Rickels K (1985) Early treatment response in anxious outpatients treated with diazepam. Acta Psychiatr Scand 72:522-528
    • (1985) Acta Psychiatr Scand , vol.72 , pp. 522-528
    • Downing, R.W.1    Rickels, K.2
  • 33
    • 0038722338 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled, fixed-dose, multicenter study of pregabalin in patients with generalized anxiety disorder
    • Feltner D, Crockatt JG, Dubovsky SJ et al (2003) A randomized, double-blind, placebo-controlled, fixed-dose, multicenter study of pregabalin in patients with generalized anxiety disorder. J Clin Psychopharmacol 23:240-249
    • (2003) J Clin Psychopharmacol , vol.23 , pp. 240-249
    • Feltner, D.1    Crockatt, J.G.2    Dubovsky, S.J.3
  • 34
    • 37349050303 scopus 로고    scopus 로고
    • Long-term efficacy of pregabalin in generalized anxiety disorder
    • Feltner D, Wittchen HU, Kavoussi R et al (2008) Long-term efficacy of pregabalin in generalized anxiety disorder. Int Clin Psychopharmacol 23:18-28
    • (2008) Int Clin Psychopharmacol , vol.23 , pp. 18-28
    • Feltner, D.1    Wittchen, H.U.2    Kavoussi, R.3
  • 35
    • 0011145384 scopus 로고    scopus 로고
    • SSRI antidepressant medications: Adverse effects and tolerability
    • Ferguson JM (2001) SSRI antidepressant medications: adverse effects and tolerability. Prim Care J Clin Psychiatry 3:22-27
    • (2001) Prim Care J Clin Psychiatry , vol.3 , pp. 22-27
    • Ferguson, J.M.1
  • 37
    • 0037460745 scopus 로고    scopus 로고
    • Relapse prevention with antidepressant drug treatment in depressive disorders: A systematic review
    • Geddes JR, Carney SM, Davies C et al (2003) Relapse prevention with antidepressant drug treatment in depressive disorders: a systematic review. Lancet 361:653-661
    • (2003) Lancet , vol.361 , pp. 653-661
    • Geddes, J.R.1    Carney, S.M.2    Davies, C.3
  • 38
    • 0034697886 scopus 로고    scopus 로고
    • Efficacy of venlafaxine extended-release capsules in nondepressed outpatients with generalized anxiety disorder: A 6-month randomized controlled trial
    • Gelenberg AJ, Lydiard RB, Rudolph RL et al (2000) Efficacy of venlafaxine extended-release capsules in nondepressed outpatients with generalized anxiety disorder: A 6-month randomized controlled trial. JAMA, 283: 3082-3088
    • (2000) JAMA, , vol.283 , pp. 3082-3088
    • Gelenberg, A.J.1    Lydiard, R.B.2    Rudolph, R.L.3
  • 39
    • 22544482687 scopus 로고    scopus 로고
    • Treatment of generalized anxiety disorder with escitalopram: Pooled results from double-blind, placebo-controlled trials
    • Goodman WK, Bose A, Wang Q (2005) Treatment of generalized anxiety disorder with escitalopram: pooled results from double-blind, placebo-controlled trials. J Affect Disord 87:161-167
    • (2005) J Affect Disord , vol.87 , pp. 161-167
    • Goodman, W.K.1    Bose, A.2    Wang, Q.3
  • 40
    • 0030799724 scopus 로고    scopus 로고
    • Cognitive behavioural and pharmacological treatment of generalised anxiety disorder: A preliminary meta-analysis
    • Gould RA, Otto MW, Pollack MH et al (1997) Cognitive behavioural and pharmacological treatment of generalised anxiety disorder: a preliminary meta-analysis. Behav Ther 28:285-305
    • (1997) Behav Ther , vol.28 , pp. 285-305
    • Gould, R.A.1    Otto, M.W.2    Pollack, M.H.3
  • 41
    • 0000238671 scopus 로고
    • The clinical global impression severity and impression scales
    • In: Rockville, MD. US Dept Health, Education and Welfare
    • Guy W (1976) The clinical global impression severity and impression scales. In: ECDEU Assessment Manual for Psychopathology. Rockville, MD. US Dept Health, Education and Welfare, 218-222
    • (1976) ECDEU Assessment Manual for Psychopathology , pp. 218-222
    • Guy, W.1
  • 42
    • 51549099524 scopus 로고
    • The assessment of anxiety states by rating
    • Hamilton M (1959) The assessment of anxiety states by rating. Br J Med Psychol 32:50-55
    • (1959) Br J Med Psychol , vol.32 , pp. 50-55
    • Hamilton, M.1
  • 43
    • 34147165983 scopus 로고    scopus 로고
    • Duloxetine as an SNRI treatment for generalized anxiety disorder: Results from a placebo and active-controlled trial
    • Hartford J, Kornstein S, LiebowitzMet al (2007) Duloxetine as an SNRI treatment for generalized anxiety disorder: results from a placebo and active-controlled trial. Int Clin Psychopharmacol 22:167-174
    • (2007) Int Clin Psychopharmacol , vol.22 , pp. 167-174
    • Hartford, J.1    Kornstein, S.2    Liebowitz, M.3
  • 44
    • 35648988598 scopus 로고    scopus 로고
    • An effect-size analysis of pharmacologic treatments for generalized anxiety disorder
    • Hidalgo RB, Tupler LA, Davidson JRT (2007) An effect-size analysis of pharmacologic treatments for generalized anxiety disorder. J Psychopharmacol 21:864-872
    • (2007) J Psychopharmacol , vol.21 , pp. 864-872
    • Hidalgo, R.B.1    Tupler, L.A.2    Davidson, J.R.T.3
  • 45
    • 0031723885 scopus 로고    scopus 로고
    • Comorbidity as a fundamental feature of generalized anxiety disorders: Results from the National Comorbidity Survey (NCS)
    • Judd LL, Kessler RC, Paulus MP et al (1998) Comorbidity as a fundamental feature of generalized anxiety disorders: results from the National Comorbidity Survey (NCS). Acta Psychiatr Scand 98(Suppl 393):6-11
    • (1998) Acta Psychiatr Scand , vol.98 , Issue.SUPPL. 393 , pp. 6-11
    • Judd, L.L.1    Kessler, R.C.2    Paulus, M.P.3
  • 46
    • 63849233377 scopus 로고    scopus 로고
    • Efficacy of pregabalin and venlafaxine-XR in generalized anxiety disorder: Results of a double-blind, placebo-controlled 8-week trial
    • E-pub ahead of print. DOI: 10.1097/YIC.0b013e32831d7980
    • Kasper S, Herman B, Nivoli G et al (2009). Efficacy of pregabalin and venlafaxine-XR in generalized anxiety disorder: results of a double-blind, placebo-controlled 8-week trial. Int Clin Psychopharmacol 2009. E-pub ahead of print. DOI: 10.1097/YIC.0b013e32831d7980
    • (2009) Int Clin Psychopharmacol 2009
    • Kasper, S.1    Herman, B.2    Nivoli, G.3
  • 47
    • 53149142767 scopus 로고    scopus 로고
    • Quetiapine as an adjunctive pharmacotherapy for the treatment of non-remitting generalized anxiety disorder: A flexible-dose, open-label pilot trial
    • [Epub ahead of print]
    • Katzman MA, Vermani M, Jacobs L et al (2008) Quetiapine as an adjunctive pharmacotherapy for the treatment of non-remitting generalized anxiety disorder: a flexible-dose, open-label pilot trial. J Anxiety Disord [Epub ahead of print]
    • (2008) J Anxiety Disord
    • Katzman, M.A.1    Vermani, M.2    Jacobs, L.3
  • 48
    • 0032697699 scopus 로고    scopus 로고
    • Impairment in pure and comorbid generalized anxiety disorder and major depression at 12 months in two national surveys
    • Kessler RC, DuPont RL, Berglund (1999) Impairment in pure and comorbid generalized anxiety disorder and major depression at 12 months in two national surveys. Am J Psychiatry 156:1915-1923
    • (1999) Am J Psychiatry , vol.156 , pp. 1915-1923
    • Kessler, R.C.1    DuPont, R.L.2    Berglund3
  • 49
    • 34248337817 scopus 로고    scopus 로고
    • Adjunctive zonisamide for treatment refractory anxiety
    • Kinrys G, Vasconcelos e Sa D, Nery F (2007) Adjunctive zonisamide for treatment refractory anxiety. Int J Clin Pract 61:1050-1053
    • (2007) Int J Clin Pract , vol.61 , pp. 1050-1053
    • Kinrys, G.1    Vasconcelos e Sa, D.2    Nery, F.3
  • 50
    • 0031970638 scopus 로고    scopus 로고
    • Buspirone and lorazepam in the treatment of generalized anxiety disorder in outpatients
    • Laakmann G, Schüle C, Lorkowski G et al (1998) Buspirone and lorazepam in the treatment of generalized anxiety disorder in outpatients. Psychopharmacol 136:357-366
    • (1998) Psychopharmacol , vol.136 , pp. 357-366
    • Laakmann, G.1    Schüle, C.2    Lorkowski, G.3
  • 51
    • 0141990724 scopus 로고    scopus 로고
    • A double-blind, randomised, placebo controlled study of venlafaxine XL in patients with generalised anxiety disorder in primary care
    • Lenox-Smith AJ, Reynolds A (2003) A double-blind, randomised, placebo controlled study of venlafaxine XL in patients with generalised anxiety disorder in primary care. Br J Gen Pract 53:772-777
    • (2003) Br J Gen Pract , vol.53 , pp. 772-777
    • Lenox-Smith, A.J.1    Reynolds, A.2
  • 52
    • 34548707910 scopus 로고    scopus 로고
    • Benzodiazepines in generalized anxiety disorder: Heterogeneity of outcomes based on a systematic review and meta-analysis of clinical trials
    • Martin JLR, Sainz-Pardo M, Furukawa TA et al (2007) Benzodiazepines in generalized anxiety disorder: heterogeneity of outcomes based on a systematic review and meta-analysis of clinical trials. J Psychopharmacol 21:774-782
    • (2007) J Psychopharmacol , vol.21 , pp. 774-782
    • Martin, J.L.R.1    Sainz-Pardo, M.2    Furukawa, T.A.3
  • 53
    • 0022610150 scopus 로고
    • Effective short-term treatment of generalized anxiety disorder with trifluoperazine
    • Mendels J, Krajewski TF, Huffer V et al (1986) Effective short-term treatment of generalized anxiety disorder with trifluoperazine. J Clin Psychiatry 47:170-174
    • (1986) J Clin Psychiatry , vol.47 , pp. 170-174
    • Mendels, J.1    Krajewski, T.F.2    Huffer, V.3
  • 54
    • 68349146747 scopus 로고    scopus 로고
    • Efficacy and tolerability of extended release quetiapine fumarate monotherapy in the treatment of GAD
    • Meredith C, Cutler A, Neijber A, She F, Eriksson H (2008) Efficacy and tolerability of extended release quetiapine fumarate monotherapy in the treatment of GAD. Eur Neuropsychopharmacol 18(suppl 4):S499-S450
    • (2008) Eur Neuropsychopharmacol , vol.18 , Issue.SUPPL. 4 , pp. 450-499
    • Meredith, C.1    Cutler, A.2    Neijber, A.3    She, F.4    Eriksson, H.5
  • 55
    • 80051549344 scopus 로고    scopus 로고
    • Adjunctive pregabalin treatment after partial response in generalized anxiety disorder: Results of a double-blind, placebo-controlled trial
    • May 16-21, 2009; San Francisco, CA
    • Miceli JJ, Ramey TS, Weaver JJ et al (2009) Adjunctive pregabalin treatment after partial response in generalized anxiety disorder: results of a double-blind, placebo-controlled trial. Presented at the 162nd Annual Meeting of the American Psychiatric Association; May 16-21, 2009; San Francisco, CA
    • (2009) Presented at the 162nd Annual Meeting of the American Psychiatric Association
    • Miceli, J.J.1    Ramey, T.S.2    Weaver, J.J.3
  • 56
    • 15444365574 scopus 로고    scopus 로고
    • A meta-analytic review of the efficacy of drug treatment in generalized anxiety disorder
    • Mitte K, Noack P, Steil R, Hautzinger M (2005) A meta-analytic review of the efficacy of drug treatment in generalized anxiety disorder. J Clin Psychopharmacol 25:141-150
    • (2005) J Clin Psychopharmacol , vol.25 , pp. 141-150
    • Mitte, K.1    Noack, P.2    Steil, R.3    Hautzinger, M.4
  • 57
    • 0036283662 scopus 로고    scopus 로고
    • Characterization of the longitudinal course of improvement in generalized anxiety disorder during long-term treatment with venlafaxine XR
    • Montgomery SA, Sheehan DV, Meoni P et al (2002) Characterization of the longitudinal course of improvement in generalized anxiety disorder during long-term treatment with venlafaxine XR. J Psychiatr Res 36:209-217
    • (2002) J Psychiatr Res , vol.36 , pp. 209-217
    • Montgomery, S.A.1    Sheehan, D.V.2    Meoni, P.3
  • 58
    • 33745373542 scopus 로고    scopus 로고
    • Efficacy and safety of pregabalin in the treatment of generalized anxiety disorder: A 6-week, multicenter, randomized, double-blind, placebo-controlled comparison of pregabalin and venlafaxine
    • Montgomery SA, Tobias K, Zornberg GL et al (2006) Efficacy and safety of pregabalin in the treatment of generalized anxiety disorder: a 6-week, multicenter, randomized, double-blind, placebo-controlled comparison of pregabalin and venlafaxine. J Clin Psychiatry 67:771-782
    • (2006) J Clin Psychiatry , vol.67 , pp. 771-782
    • Montgomery, S.A.1    Tobias, K.2    Zornberg, G.L.3
  • 59
    • 55949104118 scopus 로고    scopus 로고
    • Efficacy and safety of pregabalin in elderly people with generalised anxiety disorder
    • Montgomery S, Chatamra K, Pauer L et al (2008) Efficacy and safety of pregabalin in elderly people with generalised anxiety disorder. Br J Psychiatry 193:389-394
    • (2008) Br J Psychiatry , vol.193 , pp. 389-394
    • Montgomery, S.1    Chatamra, K.2    Pauer, L.3
  • 60
    • 12344310143 scopus 로고    scopus 로고
    • Overview of diagnosis and drug treatment of anxiety disorders
    • Nutt DJ (2005) Overview of diagnosis and drug treatment of anxiety disorders. CNS Spectrums 10:49-56
    • (2005) CNS Spectrums , vol.10 , pp. 49-56
    • Nutt, D.J.1
  • 61
    • 40349106455 scopus 로고    scopus 로고
    • Examination of the decline in symptoms of anxiety and depression in generalized anxiety disorder: Impact of anxiety sensitivity on response to pharmacotherapy
    • Olatunji BO, Feldman G, Smits JAJ et al (2008) Examination of the decline in symptoms of anxiety and depression in generalized anxiety disorder: impact of anxiety sensitivity on response to pharmacotherapy. Depress Anx 25:167-171
    • (2008) Depress Anx , vol.25 , pp. 167-171
    • Olatunji, B.O.1    Feldman, G.2    Smits, J.A.J.3
  • 62
    • 84950169241 scopus 로고    scopus 로고
    • Pregabalin treatment of GAD
    • May 13-18; Chicago, IL (Abstract NR244). Available at: Accessed February 15, 2006
    • Pande AC, Crockatt MA, Janney C et al (2000) Pregabalin treatment of GAD. Presented at: American Psychiatric Association 153rd Annual Meeting. May 13-18; Chicago, IL (Abstract NR244). Available at: http://www.psych.org/edu/other_res/lib_archives/archives/meetings/ 2000nra.pdf Accessed February 15, 2006
    • (2000) Presented at: American Psychiatric Association 153rd Annual Meeting
    • Pande, A.C.1    Crockatt, M.A.2    Janney, C.3
  • 63
    • 0037364633 scopus 로고    scopus 로고
    • Pregabalin in generalized anxiety disorder: A placebo-controlled trial
    • Pande AC, Crockatt JG, Feltner DE et al (2003) Pregabalin in generalized anxiety disorder: a placebo-controlled trial. Am J Psychiatry 160:533-540
    • (2003) Am J Psychiatry , vol.160 , pp. 533-540
    • Pande, A.C.1    Crockatt, J.G.2    Feltner, D.E.3
  • 64
    • 0036364307 scopus 로고    scopus 로고
    • Open-label evaluation of venlafaxine sustained release in outpatients with generalized anxiety disorder with comorbid depression or dysthymia: Effectiveness, tolerability and predictors of response
    • Perugi G, Frare F, Toni C et al (2002) Open-label evaluation of venlafaxine sustained release in outpatients with generalized anxiety disorder with comorbid depression or dysthymia: effectiveness, tolerability and predictors of response. Neuropsychobiol 46:145-149
    • (2002) Neuropsychobiol , vol.46 , pp. 145-149
    • Perugi, G.1    Frare, F.2    Toni, C.3
  • 65
    • 15444363963 scopus 로고    scopus 로고
    • Efficacy of pregabalin in the treatment of generalized anxiety disorder: Double-blind, placebo-controlled comparison of BID versus TID dosing
    • Pohl RB, Feltner DE, Fieve RR et al (2005) Efficacy of pregabalin in the treatment of generalized anxiety disorder: double-blind, placebo-controlled comparison of BID versus TID dosing. J Clin Psychopharmacol 25:151-158
    • (2005) J Clin Psychopharmacol , vol.25 , pp. 151-158
    • Pohl, R.B.1    Feltner, D.E.2    Fieve, R.R.3
  • 66
    • 0034965985 scopus 로고    scopus 로고
    • Paroxetine in the treatment of generalized anxiety disorder: Results of a placebo-controlled, flexible-dosage trial
    • Pollack MH, Zaninelli R, Goddard A et al (2001) Paroxetine in the treatment of generalized anxiety disorder: results of a placebo-controlled, flexible-dosage trial. J Clin Psychiatry 62:350-357
    • (2001) J Clin Psychiatry , vol.62 , pp. 350-357
    • Pollack, M.H.1    Zaninelli, R.2    Goddard, A.3
  • 67
    • 0038045771 scopus 로고    scopus 로고
    • Predictors of outcome following venlafaxine extended-release treatment of DSM-IV generalized anxiety disorder: A pooled analysis of short-and long-term studies
    • Pollack MH, Meoni P, Otto MW et al (2003) Predictors of outcome following venlafaxine extended-release treatment of DSM-IV generalized anxiety disorder: a pooled analysis of short-and long-term studies. J Clin Psychopharmacol 23:250-259
    • (2003) J Clin Psychopharmacol , vol.23 , pp. 250-259
    • Pollack, M.H.1    Meoni, P.2    Otto, M.W.3
  • 68
    • 32144450616 scopus 로고    scopus 로고
    • Olanzapine augmentation of fluoxetine for refractory generalized anxiety disorder: A placebo controlled study
    • Pollack MH, Simon NM, Zalta AK et al (2006) Olanzapine augmentation of fluoxetine for refractory generalized anxiety disorder: a placebo controlled study. Biol Psychiatry 59:211-215
    • (2006) Biol Psychiatry , vol.59 , pp. 211-215
    • Pollack, M.H.1    Simon, N.M.2    Zalta, A.K.3
  • 69
    • 52449100180 scopus 로고    scopus 로고
    • Early improvement during duloxetine treatment of generalized anxiety disorder predicts response and remission at endpoint
    • [Epub ahead of print]
    • Pollack MH, Kornstein SG, Spann ME, et al (2008) Early improvement during duloxetine treatment of generalized anxiety disorder predicts response and remission at endpoint. J Psychiatr Res [Epub ahead of print]
    • (2008) J Psychiatr Res
    • Pollack, M.H.1    Kornstein, S.G.2    Spann, M.E.3
  • 70
    • 0023885470 scopus 로고
    • Long-term treatment of anxiety and risk of withdrawal: Prospective study of clorazepate and buspirone
    • Rickels K, Schweizer E, Csanalosi I et al (1988) Long-term treatment of anxiety and risk of withdrawal: prospective study of clorazepate and buspirone. Arch Gen Psychiatr 45:444-450
    • (1988) Arch Gen Psychiatr , vol.45 , pp. 444-450
    • Rickels, K.1    Schweizer, E.2    Csanalosi, I.3
  • 71
    • 0034044185 scopus 로고    scopus 로고
    • Efficacy of extended-release venlafaxine in nondepressed outpatients with generalized anxiety disorder
    • Rickels K, Pollack MH, Sheehan DV et al (2000) Efficacy of extended-release venlafaxine in nondepressed outpatients with generalized anxiety disorder. Am J Psychiatry 157:968-974
    • (2000) Am J Psychiatry , vol.157 , pp. 968-974
    • Rickels, K.1    Pollack, M.H.2    Sheehan, D.V.3
  • 72
    • 0038811891 scopus 로고    scopus 로고
    • Paroxetine treatment of generalized anxiety disorder: A double-blind, placebo-controlled study
    • Rickels K, Zaninelli R, McCafferty J et al (2003) Paroxetine treatment of generalized anxiety disorder: a double-blind, placebo-controlled study. Am J Psychiatry 160:749-756
    • (2003) Am J Psychiatry , vol.160 , pp. 749-756
    • Rickels, K.1    Zaninelli, R.2    McCafferty, J.3
  • 73
    • 24344448269 scopus 로고    scopus 로고
    • Pregabalin for treatment of generalized anxiety disorder: A 4-week, multicenter, double-blind, placebo-controlled trial of pregabalin and alprazolam
    • Rickels K, Pollack MH, Feltner DE et al (2005) Pregabalin for treatment of generalized anxiety disorder: a 4-week, multicenter, double-blind, placebo-controlled trial of pregabalin and alprazolam. Arch Gen Psychiatry 62:1022-1030
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 1022-1030
    • Rickels, K.1    Pollack, M.H.2    Feltner, D.E.3
  • 74
    • 32244442982 scopus 로고    scopus 로고
    • Remission of generalized anxiety disorder: A review of the paroxetine clinical trials database
    • Rickels K, Rynn M, Iyengar M et al (2006) Remission of generalized anxiety disorder: a review of the paroxetine clinical trials database. J Clin Psychiatry 67:41-47
    • (2006) J Clin Psychiatry , vol.67 , pp. 41-47
    • Rickels, K.1    Rynn, M.2    Iyengar, M.3
  • 75
    • 32944454471 scopus 로고    scopus 로고
    • Characteristics and predictors of full and partial recovery from generalized anxiety disorder in primary care patients
    • Rodriguez BF, Weisberg RB, Pagano ME et al (2006) Characteristics and predictors of full and partial recovery from generalized anxiety disorder in primary care patients. J Nerv Ment Dis 194:91-97
    • (2006) J Nerv Ment Dis , vol.194 , pp. 91-97
    • Rodriguez, B.F.1    Weisberg, R.B.2    Pagano, M.E.3
  • 76
    • 0035190063 scopus 로고    scopus 로고
    • Placebo-controlled trial of sertraline in the treatment of children with generalized anxiety disorder
    • Rynn MA, Siqueland L, Rickels K (2001) Placebo-controlled trial of sertraline in the treatment of children with generalized anxiety disorder. Am J Psychiatry158:2008-2014
    • (2001) Am J Psychiatry , vol.158 , pp. 2008-2014
    • Rynn, M.A.1    Siqueland, L.2    Rickels, K.3
  • 77
    • 33845498669 scopus 로고    scopus 로고
    • Early response and 8-week treatment outcome in GAD
    • Rynn M, Khalid-Khan S, Garcia-Espana F (2006) Early response and 8-week treatment outcome in GAD. Depress Anx 23:461-465
    • (2006) Depress Anx , vol.23 , pp. 461-465
    • Rynn, M.1    Khalid-Khan, S.2    Garcia-Espana, F.3
  • 78
    • 33847253831 scopus 로고    scopus 로고
    • Efficacy and safety of extended-release venlafaxine in the treatment of generalized anxiety disorder in children and adolescents: Two placebocontrolled trials
    • Rynn MA, Riddle MA, Yeung PP et al (2007) Efficacy and safety of extended-release venlafaxine in the treatment of generalized anxiety disorder in children and adolescents: two placebocontrolled trials. Am J Psychiatry 164:290-300
    • (2007) Am J Psychiatry , vol.164 , pp. 290-300
    • Rynn, M.A.1    Riddle, M.A.2    Yeung, P.P.3
  • 79
    • 41849137610 scopus 로고    scopus 로고
    • Efficacy and safety of duloxetine in the treatment of generalized anxiety disorder: A flexible-dose, progressive-titration, placebo-controlled trial
    • Rynn M, Russell J, Erickson J et al (2008) Efficacy and safety of duloxetine in the treatment of generalized anxiety disorder: a flexible-dose, progressive-titration, placebo-controlled trial. Depress Anxiety 25:182-189
    • (2008) Depress Anxiety , vol.25 , pp. 182-189
    • Rynn, M.1    Russell, J.2    Erickson, J.3
  • 80
    • 33750340561 scopus 로고    scopus 로고
    • Preliminary support for gender differences in response to fluoxetine for generalized anxiety disorder
    • Simon NM, Zalta AK, Worthington JJ 3rd et al (2006) Preliminary support for gender differences in response to fluoxetine for generalized anxiety disorder. Depress Anx 23:373-376
    • (2006) Depress Anx , vol.23 , pp. 373-376
    • Simon, N.M.1    Zalta, A.K.2    Worthington III, J.J.3
  • 81
    • 41849148995 scopus 로고    scopus 로고
    • Quetiapine augmentation of paroxetine CR for the treatment of generalized anxiety disorder: Preliminary findings
    • Simon NM, Connor KM, LeBeau RT et al (2008) Quetiapine augmentation of paroxetine CR for the treatment of generalized anxiety disorder: preliminary findings. Psychopharmacol (Berl) 197:675-681
    • (2008) Psychopharmacol (Berl) , vol.197 , pp. 675-681
    • Simon, N.M.1    Connor, K.M.2    LeBeau, R.T.3
  • 82
    • 22044441718 scopus 로고    scopus 로고
    • Escitalopram for the treatment of GAD: Efficacy across different subgroups and outcomes
    • Stein DJ, Andersen HF, Goodman WK (2005) Escitalopram for the treatment of GAD: efficacy across different subgroups and outcomes. Ann Clin Psychiatry 17:71-75
    • (2005) Ann Clin Psychiatry , vol.17 , pp. 71-75
    • Stein, D.J.1    Andersen, H.F.2    Goodman, W.K.3
  • 83
    • 33845619513 scopus 로고    scopus 로고
    • Which factors predict placebo response in anxiety disorders and major depression? An analysis of placebo-controlled studies of escitalopram
    • Stein DJ, Baldwin DS, Dolberg OT et al (2006) Which factors predict placebo response in anxiety disorders and major depression? An analysis of placebo-controlled studies of escitalopram. J Clin Psychiatry 67:1741-1746
    • (2006) J Clin Psychiatry , vol.67 , pp. 1741-1746
    • Stein, D.J.1    Baldwin, D.S.2    Dolberg, O.T.3
  • 84
    • 58149129754 scopus 로고    scopus 로고
    • Efficacy of agomelatine in generalized anxiety disorder: A randomized, double-blind, placebo-controlled study
    • Stein DJ, Ahokas A, de Bodinat C (2008b) Efficacy of agomelatine in generalized anxiety disorder: a randomized, double-blind, placebo-controlled study. J Clin Psychopharmacol 28:561-566
    • (2008) J Clin Psychopharmacol , vol.28 , pp. 561-566
    • Stein, D.J.1    Ahokas, A.2    de Bodinat, C.3
  • 85
    • 42749093852 scopus 로고    scopus 로고
    • Efficacy of pregabalin in depressive symptoms associated with generalized anxiety disorder: A pooled analysis of 6 studies
    • Stein DJ, Baldwin DS, Baldinetti F, Baldinetti F, Mandel F (2008a) Efficacy of pregabalin in depressive symptoms associated with generalized anxiety disorder: a pooled analysis of 6 studies. Eur Neuropsychopharmacol 18:422-430
    • (2008) Eur Neuropsychopharmacol , vol.18 , pp. 422-430
    • Stein, D.J.1    Baldwin, D.S.2    Baldinetti, F.3    Baldinetti, F.4    Mandel, F.5
  • 86
    • 0037362288 scopus 로고    scopus 로고
    • Efficacy and tolerability of paroxetine for the longterm treatment of generalized anxiety disorder
    • Stocchi F, Nordera G, Jokinen RH et al (2003) Efficacy and tolerability of paroxetine for the longterm treatment of generalized anxiety disorder. J Clin Psychiatry 64:250-258
    • (2003) J Clin Psychiatry , vol.64 , pp. 250-258
    • Stocchi, F.1    Nordera, G.2    Jokinen, R.H.3
  • 87
    • 33845450824 scopus 로고    scopus 로고
    • Generalised anxiety disorder
    • Tyrer P, Baldwin DS (2006) Generalised anxiety disorder. Lancet 368:2156-2166
    • (2006) Lancet , vol.368 , pp. 2156-2166
    • Tyrer, P.1    Baldwin, D.S.2
  • 88
    • 0020525401 scopus 로고
    • Gradual withdrawal of diazepam after long-term therapy
    • Tyrer P, Owen R, Dawling S (1983) Gradual withdrawal of diazepam after long-term therapy. Lancet 321:1402-1406
    • (1983) Lancet , vol.321 , pp. 1402-1406
    • Tyrer, P.1    Owen, R.2    Dawling, S.3
  • 89
    • 10044227242 scopus 로고    scopus 로고
    • The Nottingham Study of Neurotic Disorder: Predictors of 12 year outcome of dysthymic, panic and generalised anxiety disorder
    • Tyrer P, Seivewright H, Johnson T (2004) The Nottingham Study of Neurotic Disorder: predictors of 12 year outcome of dysthymic, panic and generalised anxiety disorder. Psychol Med 34:385-394
    • (2004) Psychol Med , vol.34 , pp. 385-394
    • Tyrer, P.1    Seivewright, H.2    Johnson, T.3
  • 90
    • 0031809078 scopus 로고    scopus 로고
    • Prevalence and recognition of anxiety syndromes in five European primary care settings. A report from the WHO Study on Psychological Problems in General Health Care
    • Weiller E, Bisserbe JC, Maier W et al (1998) Prevalence and recognition of anxiety syndromes in five European primary care settings. A report from the WHO Study on Psychological Problems in General Health Care. Br J Psychiatr 173(suppl 34):18-23
    • (1998) Br J Psychiatr , vol.173 , Issue.SUPPL. 34 , pp. 18-23
    • Weiller, E.1    Bisserbe, J.C.2    Maier, W.3
  • 91
    • 19844373148 scopus 로고    scopus 로고
    • Size and burden of mental disorders in Europe: A critical review and appraisal of 27 studies
    • Wittchen H.-U, Jacobi F (2005) Size and burden of mental disorders in Europe: a critical review and appraisal of 27 studies. Eur Neuropsychopharmacol 15:357-376
    • (2005) Eur Neuropsychopharmacol , vol.15 , pp. 357-376
    • Wittchen, H.-U.1    Jacobi, F.2
  • 92
    • 0033760682 scopus 로고    scopus 로고
    • Disabilities and quality of life in pure and comorbid generalized anxiety disorder and major depression in a national survey
    • Wittchen H.-U, Carter RM, Pfisster H, Montgomery SA et al (2000) Disabilities and quality of life in pure and comorbid generalized anxiety disorder and major depression in a national survey. Int Clin Psychopharmacol 15:319-328
    • (2000) Int Clin Psychopharmacol , vol.15 , pp. 319-328
    • Wittchen, H.-U.1    Carter, R.M.2    Pfisster, H.3    Montgomery, S.A.4
  • 93
    • 0036093608 scopus 로고    scopus 로고
    • Generalized anxiety disorder and depression in primary care: Prevalence, recognition, and management
    • Wittchen H.-U, Kessler RC, Beesdo K et al (2002) Generalized anxiety disorder and depression in primary care: prevalence, recognition, and management. J Clin Psychiatry 63(suppl 8):24-34
    • (2002) J Clin Psychiatry , vol.63 , Issue.SUPPL. 8 , pp. 24-34
    • Wittchen, H.-U.1    Kessler, R.C.2    Beesdo, K.3


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