African American Patients with Chronic Rhinosinusitis Have a Distinct Phenotype of Polyposis Associated with Increased Asthma Hospitalization

Journal of Allergy and Clinical Immunology: In Practice

Volumn 4, Issue 4, 2016, Pages 658-664.e1

  Mahdavinia, Mahboobeh ^a   Benhammuda, Mohamed ^a   Codispoti, Christopher D ^a   Tobin, Mary C ^a   Losavio, Philip S ^a   Mehta, Arpita ^a   Jeffe, Jill S ^a   Bandi, Sindhura ^a   Peters, Anju T ^a   Stevens, Whitney W ^a   Landay, Alan ^a   Keshavarzian, Ali ^a   Schleimer, Robert P ^b   Batra, Pete S ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

African American; Asthma; Chronic rhinosinusitis (CRS); Nasal polyp; Race

Indexed keywords

ACETYLSALICYLIC ACID;

ADULT; AFRICAN AMERICAN; ARTICLE; ASTHMA; ATOPIC DERMATITIS; ATOPY; CHRONIC RHINOSINUSITIS; COHORT ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; DISEASE ASSOCIATION; DISEASE DURATION; DISEASE EXACERBATION; DISEASE SEVERITY; FEMALE; FOOD ALLERGY; HOSPITALIZATION; HUMAN; HYPOSMIA; ILLINOIS; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NOSE POLYP; OUTCOME ASSESSMENT; PHENOTYPE; PREVALENCE; RETROSPECTIVE STUDY; TERTIARY CARE CENTER; TREATMENT FAILURE; AGED; CHRONIC DISEASE; NASAL POLYPS; RHINITIS; SEVERITY OF ILLNESS INDEX; SINUSITIS; STATISTICS AND NUMERICAL DATA;

ADULT; AFRICAN AMERICANS; AGED; ASPIRIN; ASTHMA; CHRONIC DISEASE; FEMALE; HOSPITALIZATION; HUMANS; ILLINOIS; MALE; MIDDLE AGED; NASAL POLYPS; PHENOTYPE; RETROSPECTIVE STUDIES; RHINITIS; SEVERITY OF ILLNESS INDEX; SINUSITIS; TERTIARY CARE CENTERS;

EID: 84955315285     PISSN: 22132198     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaip.2015.11.031     Document Type: Article

References (29)

1. Fokkens, W.J., Lund, V.J., Mullol, J., Bachert, C., Alobid, I., Baroody, F., et al. EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012: a summary for otorhinolaryngologists. Rhinology 50 (2012), 1–12.
2. Bachert, C., Pawankar, R., Zhang, L., Bunnag, C., Fokkens, W.J., Hamilos, D.L., et al. ICON: chronic rhinosinusitis. World Allergy Organ J, 7, 2014, 25.
3. Hastan, D., Fokkens, W.J., Bachert, C., Newson, R.B., Bislimovska, J., Bockelbrink, A., et al. Chronic rhinosinusitis in Europe—an underestimated disease: a GA(2)LEN study. Allergy 66 (2011), 1216–1223.
4. Tomassen, P., Van Zele, T., Zhang, N., Perez-Novo, C., Van Bruaene, N., Gevaert, P., et al. Pathophysiology of chronic rhinosinusitis. Proc Am Thorac Soc 8 (2011), 115–120.
5. Kaplan, A., Canadian guidelines for chronic rhinosinusitis: clinical summary. Can Fam Physician 59 (2014), 1275–1281 e528-34.
6. Scadding, G.K., Durham, S.R., Mirakian, R., Jones, N.S., Drake-Lee, A.B., Ryan, D., et al. BSACI guidelines for the management of rhinosinusitis and nasal polyposis. Clin Exp Allergy 38 (2008), 260–275.
7. Akdis, C.A., Bachert, C., Cingi, C., Dykewicz, M.S., Hellings, P.W., Naclerio, R.M., et al. Endotypes and phenotypes of chronic rhinosinusitis: a PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol 131 (2013), 1479–1490.
8. Lotvall, J., Akdis, C.A., Bacharier, L.B., Bjermer, L., Casale, T.B., Custovic, A., et al. Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome. J Allergy Clin Immunol 127 (2011), 355–360.
9. Igartua, C., Myers, R.A., Mathias, R.A., Pino-Yanes, M., Eng, C., Graves, P.E., et al. Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma. Nat Commun, 6, 2015, 5965.
10. Torgerson, D.G., Capurso, D., Mathias, R.A., Graves, P.E., Hernandez, R.D., Beaty, T.H., et al. Resequencing candidate genes implicates rare variants in asthma susceptibility. Am J Hum Genet 90 (2012), 273–281.
11. Soler, Z.M., Mace, J.C., Litvack, J.R., Smith, T.L., Chronic rhinosinusitis, race, and ethnicity. Am J Rhinol Allergy 26 (2012), 110–116.
12. Bush, C.M., Jang, D.W., Champagne, J.P., Kountakis, S.E., Epidemiologic factors and surgical outcomes in patients with nasal polyposis and asthma. ORL J Otorhinolaryngol Relat Spec 75 (2013), 320–324.
13. Meltzer, E.O., Hamilos, D.L., Hadley, J.A., Lanza, D.C., Marple, B.F., Nicklas, R.A., et al. Rhinosinusitis: establishing definitions for clinical research and patient care. J Allergy Clin Immunol 114 (2004), 155–212.
14. Wise, S.K., Ghegan, M.D., Gorham, E., Schlosser, R.J., Socioeconomic factors in the diagnosis of allergic fungal rhinosinusitis. Otolaryngol Head Neck Surg 138 (2008), 38–42.
15. Champagne, J.P., Antisdel, J.L., Woodard, T.D., Kountakis, S.E., Epidemiologic factors affect surgical outcomes in allergic fungal sinusitis. Laryngoscope 120 (2010), 2322–2324.
16. Ghegan, M.D., Wise, S.K., Gorham, E., Schlosser, R.J., Socioeconomic factors in allergic fungal rhinosinusitis with bone erosion. Am J Rhinol 21 (2007), 560–563.
17. Barnes, K.C., Grant, A.V., Hansel, N.N., Gao, P., Dunston, G.M., African Americans with asthma: genetic insights. Proc Am Thorac Soc 4 (2007), 58–68.
18. Smith, L.A., Hatcher-Ross, J.L., Wertheimer, R., Kahn, R.S., Rethinking race/ethnicity, income, and childhood asthma: racial/ethnic disparities concentrated among the very poor. Public Health Rep 120 (2005), 109–116.
19. Pearlman, D.N., Zierler, S., Meersman, S., Kim, H.K., Viner-Brown, S.I., Caron, C., Race disparities in childhood asthma: does where you live matter?. J Natl Med Assoc 98 (2006), 239–247.
20. Joubert, B.R., Reif, D.M., Edwards, S.W., Leiner, K.A., Hudgens, E.E., Egeghy, P., et al. Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population. BMC Med Genet, 12, 2011, 25.
21. Liao, Y., Bang, D., Cosgrove, S., Dulin, R., Harris, Z., Taylor, A., et al. Surveillance of health status in minority communities—Racial and Ethnic Approaches to Community Health Across the U.S. (REACH U.S.) Risk Factor Survey, United States, 2009. MMWR Surveill Summ 60 (2011), 1–44.
22. Katotomichelakis, M., Simopoulos, E., Zhang, N., Tripsianis, G., Danielides, G., Livaditis, M., et al. Olfactory dysfunction and asthma as risk factors for poor quality of life in upper airway diseases. Am J Rhinol Allergy 27 (2013), 293–298.
23. Katotomichelakis, M., Simopoulos, E., Tripsianis, G., Balatsouras, D., Danielides, G., Kourousis, C., et al. Predictors of quality of life outcomes in chronic rhinosinusitis after sinus surgery. Eur Arch Otorhinolaryngol 271 (2014), 733–741.
24. Haruna, S., Otori, N., Moriyama, H., Nakanishi, M., Olfactory dysfunction in sinusitis with infiltration of numerous activated eosinophils. Auris Nasus Larynx 33 (2006), 23–30.
25. Litvack, J.R., Fong, K., Mace, J., James, K.E., Smith, T.L., Predictors of olfactory dysfunction in patients with chronic rhinosinusitis. Laryngoscope 118 (2008), 2225–2230.
26. Oka, H., Tsuzuki, K., Takebayashi, H., Kojima, Y., Daimon, T., Sakagami, M., Olfactory changes after endoscopic sinus surgery in patients with chronic rhinosinusitis. Auris Nasus Larynx 40 (2013), 452–457.
27. Mahdavinia, M., Suh, L.A., Carter, R.G., Stevens, W.W., Norton, J.E., Kato, A., et al. Increased noneosinophilic nasal polyps in chronic rhinosinusitis in US second-generation Asians suggest genetic regulation of eosinophilia. J Allergy Clin Immunol 135 (2015), 576–579.
28. Bachert, C., Zhang, N., Holtappels, G., De Lobel, L., van Cauwenberge, P., Liu, S., et al. Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma. J Allergy Clin Immunol 126 (2010), 962–968 968.e1-6.
29. Zhang, N., Van Zele, T., Perez-Novo, C., Van Bruaene, N., Holtappels, G., DeRuyck, N., et al. Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease. J Allergy Clin Immunol 122 (2008), 961–968.