-
1
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
Zhou, B. B. & Elledge, S. J. The DNA damage response: putting checkpoints in perspective. Nature 408, 433-439 (2000).
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
2
-
-
0037178748
-
Interfaces between the detection, signaling, and repair of DNA damage
-
Rouse, J. & Jackson, S. P. Interfaces between the detection, signaling, and repair of DNA damage. Science 297, 547-551 (2002).
-
(2002)
Science
, vol.297
, pp. 547-551
-
-
Rouse, J.1
Jackson, S.P.2
-
3
-
-
33845627082
-
Cellular responses to DNA damage: One signal, multiple choices
-
Su, T. T. Cellular responses to DNA damage: one signal, multiple choices. Annu. Rev. Genet. 40, 187-208 (2006).
-
(2006)
Annu. Rev. Genet.
, vol.40
, pp. 187-208
-
-
Su, T.T.1
-
4
-
-
50449098473
-
New players in the BRCA1-mediated DNA damage responsive pathway
-
Kim, H. & Chen, J. New players in the BRCA1-mediated DNA damage responsive pathway. Mol. Cells 25, 457-461 (2008).
-
(2008)
Mol. Cells
, vol.25
, pp. 457-461
-
-
Kim, H.1
Chen, J.2
-
5
-
-
70350504453
-
The DNA-damage response in human biology and disease
-
Jackson, S. P. & Bartek, J. The DNA-damage response in human biology and disease. Nature 461, 1071-1078 (2009).
-
(2009)
Nature
, vol.461
, pp. 1071-1078
-
-
Jackson, S.P.1
Bartek, J.2
-
6
-
-
84878918708
-
The chromatin response to DNA breaks: Leaving a mark on genome integrity
-
Smeenk, G. & van Attikum, H. The chromatin response to DNA breaks: leaving a mark on genome integrity. Annu. Rev. Biochem. 82, 55-80 (2013).
-
(2013)
Annu. Rev. Biochem.
, vol.82
, pp. 55-80
-
-
Smeenk, G.1
Van Attikum, H.2
-
7
-
-
84865364870
-
Playing the end game: DNA double-strand break repair pathway choice
-
Chapman, J. R., Taylor, M. R. & Boulton, S. J. Playing the end game: DNA double-strand break repair pathway choice. Mol. Cell 47, 497-510 (2012).
-
(2012)
Mol. Cell
, vol.47
, pp. 497-510
-
-
Chapman, J.R.1
Taylor, M.R.2
Boulton, S.J.3
-
8
-
-
77956673574
-
Epigenetic modifications in double-strand break DNA damage signaling and repair
-
Rossetto, D., Truman, A. W., Kron, S. J. & Cote, J. Epigenetic modifications in double-strand break DNA damage signaling and repair. Clin. Cancer Res. 16, 4543-4552 (2010).
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 4543-4552
-
-
Rossetto, D.1
Truman, A.W.2
Kron, S.J.3
Cote, J.4
-
9
-
-
79951974992
-
Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks
-
Moyal, L. et al. Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks. Mol. Cell 41, 529-542 (2011).
-
(2011)
Mol. Cell
, vol.41
, pp. 529-542
-
-
Moyal, L.1
-
10
-
-
79951971464
-
Regulation of homologous recombination by RNF20-dependent H2B ubiquitination
-
Nakamura, K. et al. Regulation of homologous recombination by RNF20-dependent H2B ubiquitination. Mol. Cell 41, 515-528 (2011).
-
(2011)
Mol. Cell
, vol.41
, pp. 515-528
-
-
Nakamura, K.1
-
11
-
-
84894048601
-
Histone chaperone FACT regulates homologous recombination by chromatin remodeling through interaction with RNF20
-
Oliveira, D. V. et al. Histone chaperone FACT regulates homologous recombination by chromatin remodeling through interaction with RNF20. J. Cell Sci. 127, 763-772 (2014).
-
(2014)
J. Cell Sci.
, vol.127
, pp. 763-772
-
-
Oliveira, D.V.1
-
12
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
Mailand, N. et al. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 131, 887-900 (2007).
-
(2007)
Cell
, vol.131
, pp. 887-900
-
-
Mailand, N.1
-
13
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil, C. et al. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 136, 435-446 (2009).
-
(2009)
Cell
, vol.136
, pp. 435-446
-
-
Doil, C.1
-
14
-
-
34547655427
-
CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response
-
Kim, H., Huang, J. & Chen, J. CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response. Nat. Struct. Mol. Biol. 14, 710-715 (2007).
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 710-715
-
-
Kim, H.1
Huang, J.2
Chen, J.3
-
15
-
-
34547662882
-
CCDC98 targets BRCA1 to DNA damage sites
-
Liu, Z., Wu, J. & Yu, X. CCDC98 targets BRCA1 to DNA damage sites. Nat. Struct. Mol. Biol. 14, 716-720 (2007).
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 716-720
-
-
Liu, Z.1
Wu, J.2
Yu, X.3
-
16
-
-
34249950879
-
Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response
-
Kim, H., Chen, J. & Yu, X. Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response. Science 316, 1202-1205 (2007).
-
(2007)
Science
, vol.316
, pp. 1202-1205
-
-
Kim, H.1
Chen, J.2
Yu, X.3
-
17
-
-
34249949779
-
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites
-
Sobhian, B. et al. RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. Science 316, 1198-1202 (2007).
-
(2007)
Science
, vol.316
, pp. 1198-1202
-
-
Sobhian, B.1
-
18
-
-
34547120473
-
The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response
-
Yan, J. et al. The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response. Cancer Res. 67, 6647-6656 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 6647-6656
-
-
Yan, J.1
-
19
-
-
34249946686
-
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response
-
Wang, B. et al. Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science 316, 1194-1198 (2007).
-
(2007)
Science
, vol.316
, pp. 1194-1198
-
-
Wang, B.1
-
20
-
-
0347667234
-
TRAF-interacting protein (TRIP): A novel component of the tumor necrosis factor receptor (TNFR)-and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation
-
Lee, S. Y., Lee, S. Y. & Choi, Y. TRAF-interacting protein (TRIP): a novel component of the tumor necrosis factor receptor (TNFR)-and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-kappaB activation. J. Exp. Med. 185, 1275-1285 (1997).
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1275-1285
-
-
Lee, S.Y.1
Lee, S.Y.2
Choi, Y.3
-
21
-
-
0346333095
-
The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor
-
Regamey, A. et al. The tumor suppressor CYLD interacts with TRIP and regulates negatively nuclear factor kappaB activation by tumor necrosis factor. J. Exp. Med. 198, 1959-1964 (2003).
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1959-1964
-
-
Regamey, A.1
-
22
-
-
64549157705
-
No poles encodes a predicted E3 ubiquitin ligase required for early embryonic development of Drosophila
-
Merkle, J. A. et al. no poles encodes a predicted E3 ubiquitin ligase required for early embryonic development of Drosophila. Development 136, 449-459 (2009).
-
(2009)
Development
, vol.136
, pp. 449-459
-
-
Merkle, J.A.1
-
23
-
-
35148812699
-
Early embryonic lethality caused by targeted disruption of the TRAF-interacting protein (TRIP) gene
-
Park, E. S. et al. Early embryonic lethality caused by targeted disruption of the TRAF-interacting protein (TRIP) gene. Biochem. Biophys. Res. Commun. 363, 971-977 (2007).
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.363
, pp. 971-977
-
-
Park, E.S.1
-
24
-
-
34250187776
-
TRAF-interacting protein (TRIP) is a RING-dependent ubiquitin ligase
-
Besse, A., Campos, A. D., Webster, W. K. & Darnay, B. G. TRAF-interacting protein (TRIP) is a RING-dependent ubiquitin ligase. Biochem. Biophys. Res. Commun. 359, 660-664 (2007).
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.359
, pp. 660-664
-
-
Besse, A.1
Campos, A.D.2
Webster, W.K.3
Darnay, B.G.4
-
25
-
-
77953720192
-
ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks
-
Shanbhag, N. M., Rafalska-Metcalf, I. U., Balane-Bolivar, C., Janicki, S. M. & Greenberg, R. A. ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks. Cell 141, 970-981 (2010).
-
(2010)
Cell
, vol.141
, pp. 970-981
-
-
Shanbhag, N.M.1
Rafalska-Metcalf, I.U.2
Balane-Bolivar, C.3
Janicki, S.M.4
Greenberg, R.A.5
-
26
-
-
84879463452
-
Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombination
-
Tikoo, S. et al. Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombination. EMBO J. 32, 1778-1792 (2013).
-
(2013)
EMBO J.
, vol.32
, pp. 1778-1792
-
-
Tikoo, S.1
-
27
-
-
79954528832
-
RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci
-
Hu, Y. et al. RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes Dev. 25, 685-700 (2011).
-
(2011)
Genes Dev.
, vol.25
, pp. 685-700
-
-
Hu, Y.1
-
28
-
-
79953869356
-
The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection
-
Coleman, K. A. & Greenberg, R. A. The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection. J. Biol. Chem. 286, 13669-13680 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 13669-13680
-
-
Coleman, K.A.1
Greenberg, R.A.2
-
29
-
-
34547120473
-
The ubiquitin-interacting motif-containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response
-
Yan, J. et al. The ubiquitin-interacting motif-containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response. Cancer. Res. 67, 6647-6656 (2007).
-
(2007)
Cancer. Res.
, vol.67
, pp. 6647-6656
-
-
Yan, J.1
-
30
-
-
79951488010
-
WAC a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription
-
Zhang, F. & Yu, X. WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription. Mol. Cell 41, 384-397 (2011).
-
(2011)
Mol. Cell
, vol.41
, pp. 384-397
-
-
Zhang, F.1
Yu, X.2
-
31
-
-
65249105512
-
RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells
-
Kim, J. et al. RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell 137, 459-471 (2009).
-
(2009)
Cell
, vol.137
, pp. 459-471
-
-
Kim, J.1
-
32
-
-
0037979238
-
PML colocalizes with and stabilizes the DNA damage response protein TopBP1
-
Xu, Z. X., Timanova-Atanasova, A., Zhao, R. X. & Chang, K. S. PML colocalizes with and stabilizes the DNA damage response protein TopBP1. Mol. Cell Biol. 23, 4247-4256 (2003).
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 4247-4256
-
-
Xu, Z.X.1
Timanova-Atanasova, A.2
Zhao, R.X.3
Chang, K.S.4
-
33
-
-
82755183606
-
Correct end use during end joining of multiple chromosomal double strand breaks is influenced by repair protein RAD50 DNA-dependent protein kinase DNA-PKcs, and transcription context
-
Gunn, A., Bennardo, N., Cheng, A. & Stark, J. M. Correct end use during end joining of multiple chromosomal double strand breaks is influenced by repair protein RAD50, DNA-dependent protein kinase DNA-PKcs, and transcription context. J. Biol. Chem. 286, 42470-42482 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 42470-42482
-
-
Gunn, A.1
Bennardo, N.2
Cheng, A.3
Stark, J.M.4
-
34
-
-
67650076377
-
Astrocyte elevated gene-1 contributes to the pathogenesis of neuroblastoma
-
Lee, S. G. et al. Astrocyte elevated gene-1 contributes to the pathogenesis of neuroblastoma. Oncogene 28, 2476-2484 (2009).
-
(2009)
Oncogene
, vol.28
, pp. 2476-2484
-
-
Lee, S.G.1
|