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Volumn 15, Issue 5, 2016, Pages 681-688

Advanced glycation end products are elevated in cystic fibrosis-related diabetes and correlate with worse lung function

Author keywords

Advanced glycation end products; Cystic fibrosis; Cystic fibrosis related diabetes; Receptor for advanced glycation end products

Indexed keywords

ADVANCED GLYCATION END PRODUCT; CALGRANULIN C; HEMOGLOBIN A1C; HIGH MOBILITY GROUP B1 PROTEIN; LIGAND; ADVANCED GLYCATION END PRODUCT RECEPTOR;

EID: 84955292969     PISSN: 15691993     EISSN: 18735010     Source Type: Journal    
DOI: 10.1016/j.jcf.2015.12.011     Document Type: Article
Times cited : (27)

References (46)
  • 1
    • 84922031843 scopus 로고    scopus 로고
    • Advanced glycation end products (AGEs) and the soluble receptor for AGE (sRAGE) in patients with type 1 diabetes and coeliac disease
    • [1] Bakker, S.F., Tushuizen, M.E., Gozutok, E., et al. Advanced glycation end products (AGEs) and the soluble receptor for AGE (sRAGE) in patients with type 1 diabetes and coeliac disease. Nutr Metab Cardiovasc Dis 25:2 (2015), 230–235.
    • (2015) Nutr Metab Cardiovasc Dis , vol.25 , Issue.2 , pp. 230-235
    • Bakker, S.F.1    Tushuizen, M.E.2    Gozutok, E.3
  • 2
    • 33846064113 scopus 로고    scopus 로고
    • NCBI GEO: mining tens of millions of expression profiles–database and tools update
    • [2] Barrett, T., Troup, D.B., Wilhite, S.E., et al. NCBI GEO: mining tens of millions of expression profiles–database and tools update. Nucleic Acids Res 35:Database issue (2007), D760–D765.
    • (2007) Nucleic Acids Res , vol.35 , Issue.Database issue , pp. D760-D765
    • Barrett, T.1    Troup, D.B.2    Wilhite, S.E.3
  • 3
    • 0034805902 scopus 로고    scopus 로고
    • Dysregulated NF-kappaB activation in cystic fibrosis: evidence for a primary inflammatory disorder
    • [3] Blackwell, T.S., Stecenko, A.A., Christman, J.W., Dysregulated NF-kappaB activation in cystic fibrosis: evidence for a primary inflammatory disorder. Am J Physiol Lung Cell Mol Physiol 281:1 (2001), L69–L70.
    • (2001) Am J Physiol Lung Cell Mol Physiol , vol.281 , Issue.1 , pp. L69-L70
    • Blackwell, T.S.1    Stecenko, A.A.2    Christman, J.W.3
  • 4
    • 0027718105 scopus 로고
    • Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues
    • [4] Brett, J., Schmidt, A.M., Yan, S.D., et al. Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues. Am J Pathol 143:6 (1993), 1699–1712.
    • (1993) Am J Pathol , vol.143 , Issue.6 , pp. 1699-1712
    • Brett, J.1    Schmidt, A.M.2    Yan, S.D.3
  • 5
    • 78049415026 scopus 로고    scopus 로고
    • Cystic Fibrosis Foundation Patient Registry Annual Data Report
    • CF Foundation Bethesda, MD
    • [5] CFF, Cystic Fibrosis Foundation Patient Registry Annual Data Report. 2013, CF Foundation, Bethesda, MD.
    • (2013)
    • CFF1
  • 6
    • 10744229528 scopus 로고    scopus 로고
    • The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment
    • [6] Chavakis, T., Bierhaus, A., Al-Fakhri, N., et al. The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment. J Exp Med 198:10 (2003), 1507–1515.
    • (2003) J Exp Med , vol.198 , Issue.10 , pp. 1507-1515
    • Chavakis, T.1    Bierhaus, A.2    Al-Fakhri, N.3
  • 7
    • 79955528815 scopus 로고    scopus 로고
    • A monoclonal antibody against RAGE alters gene expression and is protective in experimental models of sepsis and pneumococcal pneumonia
    • [7] Christaki, E., Opal, S.M., Keith, J.C. Jr., et al. A monoclonal antibody against RAGE alters gene expression and is protective in experimental models of sepsis and pneumococcal pneumonia. Shock 35:5 (2011), 492–498.
    • (2011) Shock , vol.35 , Issue.5 , pp. 492-498
    • Christaki, E.1    Opal, S.M.2    Keith, J.C.3
  • 8
    • 65249153029 scopus 로고    scopus 로고
    • RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes
    • [8] Coughlan, M.T., Thorburn, D.R., Penfold, S.A., et al. RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes. J Am Soc Nephrol 20:4 (2009), 742–752.
    • (2009) J Am Soc Nephrol , vol.20 , Issue.4 , pp. 742-752
    • Coughlan, M.T.1    Thorburn, D.R.2    Penfold, S.A.3
  • 9
    • 58149265310 scopus 로고    scopus 로고
    • Weight increase is associated with skeletal muscle immunostaining for advanced glycation end products, receptor for advanced glycation end products, and oxidation injury
    • [9] de la Maza, M.P., Uribarri, J., Olivares, D., et al. Weight increase is associated with skeletal muscle immunostaining for advanced glycation end products, receptor for advanced glycation end products, and oxidation injury. Rejuvenation Res 11:6 (2008), 1041–1048.
    • (2008) Rejuvenation Res , vol.11 , Issue.6 , pp. 1041-1048
    • de la Maza, M.P.1    Uribarri, J.2    Olivares, D.3
  • 10
    • 32444445050 scopus 로고    scopus 로고
    • Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells
    • [10] Demling, N., Ehrhardt, C., Kasper, M., Laue, M., Knels, L., Rieber, E.P., Promotion of cell adherence and spreading: a novel function of RAGE, the highly selective differentiation marker of human alveolar epithelial type I cells. Cell Tissue Res 323:3 (2006), 475–488.
    • (2006) Cell Tissue Res , vol.323 , Issue.3 , pp. 475-488
    • Demling, N.1    Ehrhardt, C.2    Kasper, M.3    Laue, M.4    Knels, L.5    Rieber, E.P.6
  • 11
    • 84865631414 scopus 로고    scopus 로고
    • Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas aeruginosa pneumonia in cystic fibrosis
    • [11] Entezari, M., Weiss, D.J., Sitapara, R., et al. Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas aeruginosa pneumonia in cystic fibrosis. Mol Med 18:1 (2012), 477–485.
    • (2012) Mol Med , vol.18 , Issue.1 , pp. 477-485
    • Entezari, M.1    Weiss, D.J.2    Sitapara, R.3
  • 13
    • 0038015368 scopus 로고    scopus 로고
    • Expression of S100A12 (EN-RAGE) in cystic fibrosis
    • [13] Foell, D., Seeliger, S., Vogl, T., et al. Expression of S100A12 (EN-RAGE) in cystic fibrosis. Thorax 58:7 (2003), 613–617.
    • (2003) Thorax , vol.58 , Issue.7 , pp. 613-617
    • Foell, D.1    Seeliger, S.2    Vogl, T.3
  • 14
    • 0344258132 scopus 로고    scopus 로고
    • Abnormal glutathione transport in cystic fibrosis airway epithelia
    • [14] Gao, L., Kim, K.J., Yankaskas, J.R., Forman, H.J., Abnormal glutathione transport in cystic fibrosis airway epithelia. Am J Physiol 277:1 Pt 1 (1999), L113–L118.
    • (1999) Am J Physiol , vol.277 , Issue.1 , pp. L113-L118
    • Gao, L.1    Kim, K.J.2    Yankaskas, J.R.3    Forman, H.J.4
  • 15
    • 0034880114 scopus 로고    scopus 로고
    • Blockade of receptor for advanced glycation end-products restores effective wound healing in diabetic mice
    • [15] Goova, M.T., Li, J., Kislinger, T., et al. Blockade of receptor for advanced glycation end-products restores effective wound healing in diabetic mice. Am J Pathol 159:2 (2001), 513–525.
    • (2001) Am J Pathol , vol.159 , Issue.2 , pp. 513-525
    • Goova, M.T.1    Li, J.2    Kislinger, T.3
  • 16
    • 0033603241 scopus 로고    scopus 로고
    • RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides
    • [16] Hofmann, M.A., Drury, S., Fu, C., et al. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 97:7 (1999), 889–901.
    • (1999) Cell , vol.97 , Issue.7 , pp. 889-901
    • Hofmann, M.A.1    Drury, S.2    Fu, C.3
  • 17
    • 0028851635 scopus 로고
    • The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system
    • [17] Hori, O., Brett, J., Slattery, T., et al. The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J Biol Chem 270:43 (1995), 25752–25761.
    • (1995) J Biol Chem , vol.270 , Issue.43 , pp. 25752-25761
    • Hori, O.1    Brett, J.2    Slattery, T.3
  • 18
    • 84891498578 scopus 로고    scopus 로고
    • Hyperglycemia impedes lung bacterial clearance in a murine model of cystic fibrosis-related diabetes
    • [18] Hunt, W.R., Zughaier, S.M., Guentert, D.E., et al. Hyperglycemia impedes lung bacterial clearance in a murine model of cystic fibrosis-related diabetes. Am J Physiol Lung Cell Mol Physiol 306:1 (2014), L43–L49.
    • (2014) Am J Physiol Lung Cell Mol Physiol , vol.306 , Issue.1 , pp. L43-L49
    • Hunt, W.R.1    Zughaier, S.M.2    Guentert, D.E.3
  • 19
    • 84890080324 scopus 로고    scopus 로고
    • Hypoxia promotes danger-mediated inflammation via receptor for advanced glycation end products in cystic fibrosis
    • [19] Iannitti, R.G., Casagrande, A., De Luca, A., et al. Hypoxia promotes danger-mediated inflammation via receptor for advanced glycation end products in cystic fibrosis. Am J Respir Crit Care Med 188:11 (2013), 1338–1350.
    • (2013) Am J Respir Crit Care Med , vol.188 , Issue.11 , pp. 1338-1350
    • Iannitti, R.G.1    Casagrande, A.2    De Luca, A.3
  • 20
    • 0142039004 scopus 로고    scopus 로고
    • The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site
    • [20] Ishihara, K., Tsutsumi, K., Kawane, S., Nakajima, M., Kasaoka, T., The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site. FEBS Lett 550:1–3 (2003), 107–113.
    • (2003) FEBS Lett , vol.550 , Issue.1-3 , pp. 107-113
    • Ishihara, K.1    Tsutsumi, K.2    Kawane, S.3    Nakajima, M.4    Kasaoka, T.5
  • 21
    • 84868111331 scopus 로고    scopus 로고
    • Elevated serum levels of AGEs, sRAGE, and pentosidine in Tunisian patients with severity of diabetic retinopathy
    • [21] Kerkeni, M., Saidi, A., Bouzidi, H., Ben Yahya, S., Hammami, M., Elevated serum levels of AGEs, sRAGE, and pentosidine in Tunisian patients with severity of diabetic retinopathy. Microvasc Res 84:3 (2012), 378–383.
    • (2012) Microvasc Res , vol.84 , Issue.3 , pp. 378-383
    • Kerkeni, M.1    Saidi, A.2    Bouzidi, H.3    Ben Yahya, S.4    Hammami, M.5
  • 23
    • 0034759112 scopus 로고    scopus 로고
    • Presence of cystic fibrosis-related diabetes mellitus is tightly linked to poor lung function in patients with cystic fibrosis: data from the European epidemiologic registry of cystic fibrosis
    • [23] Koch, C., Rainisio, M., Madessani, U., et al. Presence of cystic fibrosis-related diabetes mellitus is tightly linked to poor lung function in patients with cystic fibrosis: data from the European epidemiologic registry of cystic fibrosis. Pediatr Pulmonol 32:5 (2001), 343–350.
    • (2001) Pediatr Pulmonol , vol.32 , Issue.5 , pp. 343-350
    • Koch, C.1    Rainisio, M.2    Madessani, U.3
  • 24
    • 0027416057 scopus 로고
    • Diabetes mellitus in cystic fibrosis: genetic and immunological markers
    • [24] Lanng, S., Thorsteinsson, B., Pociot, F., et al. Diabetes mellitus in cystic fibrosis: genetic and immunological markers. Acta Paediatr 82:2 (1993), 150–154.
    • (1993) Acta Paediatr , vol.82 , Issue.2 , pp. 150-154
    • Lanng, S.1    Thorsteinsson, B.2    Pociot, F.3
  • 25
    • 84921327918 scopus 로고    scopus 로고
    • Diabetes-related mortality in adults with cystic fibrosis. Role of genotype and sex
    • [25] Lewis, C., Blackman, S.M., Nelson, A., et al. Diabetes-related mortality in adults with cystic fibrosis. Role of genotype and sex. Am J Respir Crit Care Med 191:2 (2015), 194–200.
    • (2015) Am J Respir Crit Care Med , vol.191 , Issue.2 , pp. 194-200
    • Lewis, C.1    Blackman, S.M.2    Nelson, A.3
  • 26
    • 37749005803 scopus 로고    scopus 로고
    • Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection
    • [26] Lutterloh, E.C., Opal, S.M., Pittman, D.D., et al. Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection. Crit Care, 11(6), 2007, R122.
    • (2007) Crit Care , vol.11 , Issue.6 , pp. R122
    • Lutterloh, E.C.1    Opal, S.M.2    Pittman, D.D.3
  • 27
    • 65249151394 scopus 로고    scopus 로고
    • Activation of critical, host-induced, metabolic and stress pathways marks neutrophil entry into cystic fibrosis lungs
    • [27] Makam, M., Diaz, D., Laval, J., et al. Activation of critical, host-induced, metabolic and stress pathways marks neutrophil entry into cystic fibrosis lungs. Proc Natl Acad Sci U S A 106:14 (2009), 5779–5783.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.14 , pp. 5779-5783
    • Makam, M.1    Diaz, D.2    Laval, J.3
  • 28
    • 0032741165 scopus 로고    scopus 로고
    • CDNA cloning of a novel secreted isoform of the human receptor for advanced glycation end products and characterization of cells co-expressing cell-surface scavenger receptors and Swedish mutant amyloid precursor protein
    • [28] Malherbe, P., Richards, J.G., Gaillard, H., et al. CDNA cloning of a novel secreted isoform of the human receptor for advanced glycation end products and characterization of cells co-expressing cell-surface scavenger receptors and Swedish mutant amyloid precursor protein. Brain Res Mol Brain Res 71:2 (1999), 159–170.
    • (1999) Brain Res Mol Brain Res , vol.71 , Issue.2 , pp. 159-170
    • Malherbe, P.1    Richards, J.G.2    Gaillard, H.3
  • 30
    • 84924370818 scopus 로고    scopus 로고
    • The role of receptor for advanced glycation end products in airway inflammation in CF and CF related diabetes
    • [30] Mulrennan, S., Baltic, S., Aggarwal, S., et al. The role of receptor for advanced glycation end products in airway inflammation in CF and CF related diabetes. Sci Rep, 5, 2015, 8931.
    • (2015) Sci Rep , vol.5 , pp. 8931
    • Mulrennan, S.1    Baltic, S.2    Aggarwal, S.3
  • 31
    • 39649118422 scopus 로고    scopus 로고
    • Circulating advanced glycation end products (AGEs) and soluble form of receptor for AGEs (sRAGE) are independent determinants of serum monocyte chemoattractant protein-1 (MCP-1) levels in patients with type 2 diabetes
    • [31] Nakamura, K., Yamagishi, S., Adachi, H., et al. Circulating advanced glycation end products (AGEs) and soluble form of receptor for AGEs (sRAGE) are independent determinants of serum monocyte chemoattractant protein-1 (MCP-1) levels in patients with type 2 diabetes. Diabetes Metab Res Rev 24:2 (2008), 109–114.
    • (2008) Diabetes Metab Res Rev , vol.24 , Issue.2 , pp. 109-114
    • Nakamura, K.1    Yamagishi, S.2    Adachi, H.3
  • 32
    • 0026659883 scopus 로고
    • Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins
    • [32] Neeper, M., Schmidt, A.M., Brett, J., et al. Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins. J Biol Chem 267:21 (1992), 14998–15004.
    • (1992) J Biol Chem , vol.267 , Issue.21 , pp. 14998-15004
    • Neeper, M.1    Schmidt, A.M.2    Brett, J.3
  • 33
    • 65849522497 scopus 로고    scopus 로고
    • Cystic fibrosis
    • [33] O'Sullivan, B.P., Freedman, S.D., Cystic fibrosis. Lancet 373:9678 (2009), 1891–1904.
    • (2009) Lancet , vol.373 , Issue.9678 , pp. 1891-1904
    • O'Sullivan, B.P.1    Freedman, S.D.2
  • 34
    • 54049139979 scopus 로고    scopus 로고
    • Potential role of high-mobility group box 1 in cystic fibrosis airway disease
    • [34] Rowe, S.M., Jackson, P.L., Liu, G., et al. Potential role of high-mobility group box 1 in cystic fibrosis airway disease. Am J Respir Crit Care Med 178:8 (2008), 822–831.
    • (2008) Am J Respir Crit Care Med , vol.178 , Issue.8 , pp. 822-831
    • Rowe, S.M.1    Jackson, P.L.2    Liu, G.3
  • 35
    • 0026650438 scopus 로고
    • Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface
    • [35] Schmidt, A.M., Vianna, M., Gerlach, M., et al. Isolation and characterization of two binding proteins for advanced glycosylation end products from bovine lung which are present on the endothelial cell surface. J Biol Chem 267:21 (1992), 14987–14997.
    • (1992) J Biol Chem , vol.267 , Issue.21 , pp. 14987-14997
    • Schmidt, A.M.1    Vianna, M.2    Gerlach, M.3
  • 36
    • 52749084063 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes
    • [36] Soro-Paavonen, A., Watson, A.M., Li, J., et al. Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes. Diabetes 57:9 (2008), 2461–2469.
    • (2008) Diabetes , vol.57 , Issue.9 , pp. 2461-2469
    • Soro-Paavonen, A.1    Watson, A.M.2    Li, J.3
  • 37
    • 0030811664 scopus 로고    scopus 로고
    • Advanced glycation end products and their receptors co-localise in rat organs susceptible to diabetic microvascular injury
    • [37] Soulis, T., Thallas, V., Youssef, S., et al. Advanced glycation end products and their receptors co-localise in rat organs susceptible to diabetic microvascular injury. Diabetologia 40:6 (1997), 619–628.
    • (1997) Diabetologia , vol.40 , Issue.6 , pp. 619-628
    • Soulis, T.1    Thallas, V.2    Youssef, S.3
  • 38
    • 77958152154 scopus 로고    scopus 로고
    • Update on cystic fibrosis-related diabetes
    • [38] Stecenko, A.A., Moran, A., Update on cystic fibrosis-related diabetes. Curr Opin Pulm Med 16:6 (2010), 611–615.
    • (2010) Curr Opin Pulm Med , vol.16 , Issue.6 , pp. 611-615
    • Stecenko, A.A.1    Moran, A.2
  • 39
    • 0034682315 scopus 로고    scopus 로고
    • Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases
    • [39] Taguchi, A., Blood, D.C., del Toro, G., et al. Blockade of RAGE-amphoterin signalling suppresses tumour growth and metastases. Nature 405:6784 (2000), 354–360.
    • (2000) Nature , vol.405 , Issue.6784 , pp. 354-360
    • Taguchi, A.1    Blood, D.C.2    del Toro, G.3
  • 40
    • 0033844485 scopus 로고    scopus 로고
    • Inflammation and infection in naive human cystic fibrosis airway grafts
    • [40] Tirouvanziam, R., de Bentzmann, S., Hubeau, C., et al. Inflammation and infection in naive human cystic fibrosis airway grafts. Am J Respir Cell Mol Biol 23:2 (2000), 121–127.
    • (2000) Am J Respir Cell Mol Biol , vol.23 , Issue.2 , pp. 121-127
    • Tirouvanziam, R.1    de Bentzmann, S.2    Hubeau, C.3
  • 41
    • 64249138285 scopus 로고    scopus 로고
    • The receptor for advanced glycation end products impairs host defense in pneumococcal pneumonia
    • [41] van Zoelen, M.A., Schouten, M., de Vos, A.F., et al. The receptor for advanced glycation end products impairs host defense in pneumococcal pneumonia. J Immunol 182:7 (2009), 4349–4356.
    • (2009) J Immunol , vol.182 , Issue.7 , pp. 4349-4356
    • van Zoelen, M.A.1    Schouten, M.2    de Vos, A.F.3
  • 42
    • 68549132260 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia
    • [42] van Zoelen, M.A., van der Sluijs, K.F., Achouiti, A., et al. Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia. Virology 391:2 (2009), 265–273.
    • (2009) Virology , vol.391 , Issue.2 , pp. 265-273
    • van Zoelen, M.A.1    van der Sluijs, K.F.2    Achouiti, A.3
  • 43
    • 0040886358 scopus 로고    scopus 로고
    • S100A12 is expressed exclusively by granulocytes and acts independently from MRP8 and MRP14
    • [43] Vogl, T., Propper, C., Hartmann, M., et al. S100A12 is expressed exclusively by granulocytes and acts independently from MRP8 and MRP14. J Biol Chem 274:36 (1999), 25291–25296.
    • (1999) J Biol Chem , vol.274 , Issue.36 , pp. 25291-25296
    • Vogl, T.1    Propper, C.2    Hartmann, M.3
  • 44
    • 67349178683 scopus 로고    scopus 로고
    • Nutritional decline in cystic fibrosis related diabetes: the effect of intensive nutritional intervention
    • [44] White, H., Pollard, K., Etherington, C., et al. Nutritional decline in cystic fibrosis related diabetes: the effect of intensive nutritional intervention. J Cyst Fibros 8:3 (2009), 179–185.
    • (2009) J Cyst Fibros , vol.8 , Issue.3 , pp. 179-185
    • White, H.1    Pollard, K.2    Etherington, C.3
  • 45
    • 84881118554 scopus 로고    scopus 로고
    • Cellular signalling of the receptor for advanced glycation end products (RAGE)
    • [45] Xie, J., Mendez, J.D., Mendez-Valenzuela, V., Aguilar-Hernandez, M.M., Cellular signalling of the receptor for advanced glycation end products (RAGE). Cell Signal 25:11 (2013), 2185–2197.
    • (2013) Cell Signal , vol.25 , Issue.11 , pp. 2185-2197
    • Xie, J.1    Mendez, J.D.2    Mendez-Valenzuela, V.3    Aguilar-Hernandez, M.M.4
  • 46
    • 0013615899 scopus 로고    scopus 로고
    • RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease
    • [46] Yan, S.D., Chen, X., Fu, J., et al. RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease. Nature 382:6593 (1996), 685–691.
    • (1996) Nature , vol.382 , Issue.6593 , pp. 685-691
    • Yan, S.D.1    Chen, X.2    Fu, J.3


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