Fabrication and efficacy evaluation of chloroquine nanoparticles in CFA-induced arthritic rats using TNF-α ELISA

European Journal of Pharmaceutical Sciences

Volumn 84, Issue , 2016, Pages 1-8

  Bhalekar, Mangesh R ^a   Upadhaya, Prashant G ^a   Madgulkar, Ashwini R ^a  

^a AISSMS COLLEGE OF PHARMACY   (India)

Author keywords

Chloroquine; Rheumatoid arthritis; Solid lipid nanoparticles; TNF ELISA assay

Indexed keywords

CHLOROQUINE; NANOCARRIER; SOLID LIPID NANOPARTICLE; TUMOR NECROSIS FACTOR ALPHA; ANTIRHEUMATIC AGENT; LIPID; NANOPARTICLE; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BONE EROSION; CARTILAGE DEGENERATION; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISEASE COURSE; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG INDUCED DISEASE; DRUG SCREENING; ENZYME LINKED IMMUNOSORBENT ASSAY; EX VIVO STUDY; FREEZE DRYING; HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY; HISTOPATHOLOGY; IN VIVO STUDY; MALE; NANOFABRICATION; NONHUMAN; PARTICLE SIZE; PAW; PRIORITY JOURNAL; RADIATION SCATTERING; RAT; RHEUMATOID ARTHRITIS; SCANNING ELECTRON MICROSCOPY; VOLUME; X RAY DIFFRACTION; ZETA POTENTIAL; ANIMAL; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; ARTICULAR CARTILAGE; BONE; CHEMISTRY; FOOT; IMMUNOLOGY; KNEE; METABOLISM; PATHOLOGY; SMALL INTESTINE; SYNOVIAL FLUID; TREATMENT OUTCOME; WISTAR RAT;

ANIMALS; ANTIRHEUMATIC AGENTS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; BONE AND BONES; CARTILAGE, ARTICULAR; CHLOROQUINE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FOOT; INTESTINE, SMALL; KNEE JOINT; LIPIDS; MALE; NANOPARTICLES; RATS; RATS, WISTAR; SYNOVIAL FLUID; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84955290406     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2016.01.009     Document Type: Article

References (33)

1. O.A. Adegoke, C.P. Babalola, O.S. Oshitade, and A.A. Famuyiwa Determination of physicochemical properties of pyronaridine: a new antimalarial drug Pak. J. Pharm. Sci. 19 1 2006 1 6
2. N.J. Barton, D.A. Stevens, J.P. Hughes, A.G. Rossi, I.P. Chessell, A.J. Reeve, and D.S. McQueen Demonstration of a novel technique to quantitatively assess inflammatory mediators and cells in rat knee joints J. Inflamm. 4 13 2007 1 8
3. B. Betschart, and S. Steiger Quantitative determination of chloroquine and desethylchloroquine in biological fluids by high performance thin layer chromatography Acta Trop. 43 2 1986 125 130
4. M.R. Bhalekar, V. Pokharkar, A. Madgulkar, N. Patil, and N. Patil Preparation and evaluation of miconazole nitrate-loaded solid lipid nanoparticles for topical delivery AAPS PharmSciTech 10 1 2009 289 296
5. M.R. Bhalekar, P.G. Upadhaya, A.R. Madgulkar, S.J. Kshirsagar, A. Dube, and U.S. Bartakke In-vivo Bioavailability and Lymphatic Uptake Evaluation of Lipid Nanoparticulates of Darunavir 2015 (Drug deliv in press)
6. M.R. Bhalekar, P.G. Upadhaya, S.D. Nalawade, A.R. Madgulkar, and S.J. Kshirsagar Anti-rheumatic activity of chloroquine-SLN gel on Wistar rats using complete Freund's adjuvant (CFA) model Indian J. Rheumatol. 10 2 2015 58 64
7. J.A. Champion, Y.K. Katare, and S. Mitragotri Particle shape: a new design parameter for micro- and nanoscale drug delivery carriers J. Control. Release 121 1-2 2007 3 9
8. S. Ekambaram, S.S. Perumal, and V. Subramanian Evaluation of antiarthritic activity of Strychnos potatorum Linn seeds in Freund's adjuvant induced arthritic rat model BMC Complement. Altern. Med. 10 2010 56
9. O. Eseyin, A. Ebong, A. Ubobre, J. Ekarika, and I. Udo Changes in some pharmacokinetics parameters of chloroquine by Gnetum africana Maced. J. Med. Sci. 5 3 2012 275 279
10. M. Feldmann, F.M. Brennan, and R.N. Maini Role of cytokines in rheumatoid arthritis Annu. Rev. Immunol. 14 1996 397 440
11. A. Freedman Chloroquine and rheumatoid arthritis; a short-term controlled trial Ann. Rheum. Dis. 15 3 1956 251 258
12. M. Gadhiri, F. Shohreh, D. Delaram, R.N. Abdolhossein, D. Majid, A. Vatanara, and A.A. Rahimi Loading hydrophilic drug in solid lipid media as nanoparticles: statistical modeling of entrapment efficiency and particle size Int. J. Pharm. 424 1-2 2012 128 137
13. B. Gajre, C. Dalwadi, and R. Patel Formulation and optimization of itraconazole polymeric lipid hybrid nanoparticles (Lipomer) using Box-Behnken DARU J. Pharm. Sci. 23 3 2015 23 33
14. M. Gambhire, M. Bhalekar, and B. Shrivastava Bioavailability assessment of simvastatin loaded solid lipid nanoparticles after oral administration Asian J. Pharm. Sci. 6 6 2011 251 258
15. L.F. Huang, Y.Z. Du, X.Y. Ying, J. You, F.Q. Hu, H. Yuan, and S. Zeng Solid lipid nanoparticles prepared by solvent diffusion method in a nanoreactor system Colloids Surf. B 61 2 2008 132 137
16. C.H. Jang, J.H. Choi, M.S. Byun, and D.M. Jue Chloroquine inhibits production of TNF-α, IL-1β and IL-6 from lipopolysaccharide-stimulated human monocytes/macrophages by different modes Rheumatology 45 6 2006 703 710
17. M. Lind, J. Jacobsen, R. Holm, and A. Müllertz Intestinal lymphatic transport of halofantrine in rats assessed using a chylomicron flow blocking approach: the influence of polysorbate 60 and 80 Eur. J. Pharm. Sci. 35 2008 211 218
18. C. Loo, M. Basri, R. Ismail, H. Lau, B. Tejo, M. Kanthimathi, H. Hassan, and Y. Choo Effect of composition in nanostructured lipid carriers (NLC) on skin hydration and occlusion Int. J. Nanomedicine 8 2013 13 22
19. V. Majithia, and S. Geraci Rheumatoid arthritis: diagnosis and management Am. J. Med. 120 2007 936 939
20. R.H. Müller, K. Mader, and S. Gohla Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art Eur. J. Pharm. Biopharm. 50 1 2000 161 177
21. A.B. Kovacevic, R.H. Muller, S.D. Savic, G.M. Vuleta, and C.M. Keck Solid lipid nanoparticles (SLN) stabilized with polyhydroxy surfactants: preparation, characterization and physical stability investigation Colloids Surf. A 444 2014 15 25
22. L. Pachuau, and B. Mazumder A study on the effects of different surfactants on ethylcellulose microspheres Int. J. Pharm. Technol. Res. 1 4 2009 966 971
23. M. Piecyk, and P. Anderson Signal transduction in rheumatoid arthritis Best Pract. Res. Clin. Rheumatol. 15 2001 789 803
24. P.R. Ravi, H. Kathuria, N. Aditya, S. Malekar, and R. Vats Lipid nanoparticles for oral delivery of raloxifene: optimization, stability, in vivo evaluation and uptake mechanism Eur. J. Pharm. Biopharm. 87 1 2014 114 124
25. L.H. Reddy, and R.S.R. Murthy Lymphatic transport of orally administered drug Indian J. Exp. Biol. 40 2002 1097 1109
26. E. Roger, F. Lagarce, E. Garcion, and J.P. Benoit Biopharmaceutical parameters to consider in order to alter the fate of nanocarriers after oral delivery Nanomedicine 5 2 2010 287 306
27. R.I. Rynes Antimalarial drugs in the treatment of rheumatological diseases Br. J. Rheumatol. 36 7 1997 799 805
28. G. Sahay, D.Y. Alakhova, and A.V. Kabanov Endocytosis of nanomedicines J. Control. Release 145 2010 182 195
29. U. Snekhalatha, M. Anburajan, B.,. Venkatraman, and M. Menaka Evaluation of complete Freund's adjuvant-induced arthritis in a Wistar rat model comparison of thermography and histopathology Z. Rheumatol. 72 4 2012 375 382
30. L. Su, J. Zhaoshuai, Z. Meijuan, N. Xin, S. Yijie, and G. Cheng Preparation, characterization, pharmacokinetics and tissue distribution of solid lipid nanoparticles loaded with tetrandrine AAPS PharmSciTech 12 3 2011 1011 1018
31. S. Sweeney, and G. Firestein Rheumatoid arthritis: regulation of synovial inflammation Int. J. Biol. Chem. Cell Biol. 36 2004 372 378
32. E. Woode, E. Boakye-Gyasi, C. Danquah, and D. Ansah Anti-arthritic effects of Palisota hirsuta K. Schum. Leaf extract in Freund's adjuvant-induced arthritis in rats Int. J. Pharmacol. 5 2009 181 190
33. J. Ye, Q. Wang, X. Zhou, and N. Zhang Injectable actarit-loaded solid lipid nanoparticles as passive targeting therapeutic agents for rheumatoid arthritis Int. J. Pharm. 352 2008 273 279