Changes in some pharmacokinetics parameters of chloroquine by Gnetum Africana

Macedonian Journal of Medical Sciences

Volumn 5, Issue 3, 2012, Pages 275-279

  Eseyin, Olorunfemi ^a   Ebong, Aniekan ^a   Ubobre, Anefiok ^a   Ekarika, Johnson ^a   Udo, Imo ^a  

^a UNIVERSITY OF UYO   (Nigeria)

Author keywords

Chloroquine; Gnetum africana; Pharmacokinetics; Phytochemical screening; Proximate analysis

Indexed keywords

ALKALOID; ANTIINFLAMMATORY AGENT; CALCIUM; CARBOHYDRATE; CHLOROQUINE; COPPER; CRUDE PROTEIN; FAT; FLAVONOID; GNETUM AFRICANA EXTRACT; LEAD; MAGNESIUM; PHLOBATANIN; PLANT EXTRACT; POTASSIUM; SODIUM; STEROID; TANNIN DERIVATIVE; UNCLASSIFIED DRUG; VEGETABLE PROTEIN; ZINC;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CALORIE; CONTROLLED STUDY; GNETUM; GNETUM AFRICANA; LD 50; MAXIMUM PLASMA CONCENTRATION; MOISTURE; NONHUMAN; PHYTOCHEMISTRY; PLANT FIBER; PLANT LEAF; RAT; SPECTROPHOTOMETRY;

EID: 84867759731     PISSN: 18575749     EISSN: 18575773     Source Type: Journal    
DOI: 10.3889/MJMS.1857-5773.2012.0220     Document Type: Article

References (28)

1. Wiser M. Mechanism of drug action and resistance (focus on antimalarials). Tulane University, 2003.
2. Sanchez CP, McLean JE, Rohrbach P, Fidock DA, Stein WD, Lanzer M. Evidence for a pfcrt-associated chloroquine efflux system in the human malaria parasite Plasmodium falciparum. Biochemistry. 2005;44 (29): 9862-9870.
3. Mason P. Drug-food interactions (1) food and Medicines. Continuing professional development. The Pharmaceutical Journal. 2002;269:571-573.
4. Ali, BH, Al-Qarawi, A. and Mousa, HM. Effect of grapefruit juice on plasma chlorquine kinetics in mice. Clinical and Experimental Pharmacology and Physiology, 2002;29 (8): 704-706.
5. Owoyale JA, Aliu YO, Ayodele JT. Influence of dietary spinach (Amarathion Linn.) on chloroquine blood level in the rabbit. Oriental Journal of Medicine. 1995;7:12-13.
6. Oguntola S. Why bitterleaf may affect your health negatively. Nigerian. Tribune, Friday 28th July, 2006.
7. Nwafor SV, Akah PA, Okoli CO, Onyirioham AC, Nworu CS. Interaction between chloroquine sulphate and aqueous extract of Azadirachta indica A Juss (Meliaceae) in rabbits. Acta Pharmaceutica. 2003;53(4):305-11.
8. O'Brien D, Haddad AR. Consulting patients on drug-food interactions. U. S. Pharmacist. 2002;22(6).
9. Eseyin OA, Edoho EJ, Igboasoiyi AC, Nwadiukwu E, Ekpo A. Effects of the leaf extract of Telfairia occidentalis on the pharmacokinetic of chloroquine. International Journal of Biological Chemistry. 2007;1(4):256-260.
10. Igboasoiyi AC, Eseyin OA, Udoma NF. The effect of ethanolic extract of Vernonia amygdalina leaves on some pharmacokinetic parameters of chloroquine in rats. Research Journal of Pharmacology. 2008;2(2):24-27.
11. Etukudo I. Ethno botany: conventional and Traditional uses of plants. The Verdit press, Uyo, 2003.
12. Itah AY. Screening of plants for fungal properties. Trans Nig Soc Bio Conserv. 1996;4(1):26-40.
13. Ekop AS. Determination of chemical composition of Gnetum africana seeds. Pak J Nutrition. 2007;6(1): 40-43.
14. Caprette DR. Preparation and use of standard curves. Rice University,2000.
15. AOAC. Official methods of Analysis. 15th ed. Association of Official Analytical Chemists, Arlington, 1990.
16. Harbone JB. Phytochemical methods. London, Chapman and Hill, 1973.
17. Sofowora ER. Guidelines for research promotion and development in traditional medicine. Nigeria Journal of Pharmacy. 1980;11:117-118.
18. Guengerich FP. Role of cytochrome P450 enzyme in drugdrug interaction. Advance Pharmacol. 1997;43:7-35.
19. Lin JH, Lu AYA. Inhibition and induction of cytochrome P450 and the clinical implications. Clinical Pharmacokinetics. 1998;35:361-390.
20. Ioannides C. Drug-phytochemical interactions. Inflammopharmacology. 2003;11(1):7-42.
21. Schrauzer GN. "The discovery of essential trace elements: An outline of the history of biological trace elements research". In: biochemistry of essential trace elements, edited by Earl Frieden. Plenum, New York, 1984:17-31.
22. Mechesney EW, Fasco MJ, Banks WF. The metabolism of CQ in man during and after repeated oral dosage. Journal of Pharmacy and Experimental Therapeutics. 1967;158:323-331.
23. Gustafsson LL, Walker O, Alvan G, Beermann B, Estevez F, Gleisner L, Sjoqvist F. Disposition of chloroquine in man after single intravenous and oral doses. British J Clinical Pharmacol. 1983;15:471-479.
24. Rowhand M, Tozer TW. Clinical pharmacokinetics-concepts and applications. 3ed. Lippincott Williams and Wilking, 1995.
25. Wallace AW, Amsden GW. Is it really Ok to take this with food? Old interactions with new twist. The Journal of Pharmacology. 2002;42:437-443.
26. Jaeger A, Flesch F. Chloroquine. IPCS, 1994. Available online at http://www.inchem.org/documents/pims/pharm/chloroqu.htm
27. Bonate PL, Howard DR. Pharmacokinetics in drug development: clinical design and analysis (1). American association of pharmaceutical scientists, Arlington, VA, 2004: 235-278.
28. Okafor JC, Omoradion F, Amaja FI. Non-timber forest products (Nigeria): Consultancy paper prepared by the Evaluation and Co-ordination Unit (FORMECU) and Federal Department of Forestry (FDP) Abuja, Nigeria, 1994:8.