Oxytocin use during Caesarean sections in Denmark - Are we getting the dose right?

Acta Anaesthesiologica Scandinavica

Volumn 60, Issue 1, 2016, Pages 18-25

  Kjaer B N ^a   Kroigaard M ^b   Garvey, L H ^b  

^a AALBORG UNIVERSITY HOSPITAL   (Denmark)

^b GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

OXYTOCIN; OXYTOCIC AGENT; TRYPTASE;

ABORTION; ADULT; ARTICLE; CESAREAN SECTION; CLINICAL ARTICLE; DENMARK; DRUG USE; ELECTIVE SURGERY; EMERGENCY SURGERY; FEMALE; HOT FLUSH; HUMAN; HYPOTENSION; MEDICAL RECORD REVIEW; OBSTETRIC ANESTHESIA; OBSTETRICIAN; PRIORITY JOURNAL; PROVOCATION TEST; TACHYCARDIA; TELEPHONE INTERVIEW; VAGINAL DELIVERY; YOUNG ADULT; COHORT ANALYSIS; DOSE RESPONSE; DRUG HYPERSENSITIVITY; HEALTH CARE SURVEY; PREGNANCY; PROCEDURES; RETROSPECTIVE STUDY; TELEPHONE;

ADULT; CESAREAN SECTION; COHORT STUDIES; DENMARK; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG HYPERSENSITIVITY; FEMALE; HEALTH CARE SURVEYS; HUMANS; OXYTOCICS; OXYTOCIN; PREGNANCY; RETROSPECTIVE STUDIES; TELEPHONE; TRYPTASES; YOUNG ADULT;

EID: 84955173190     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/aas.12603     Document Type: Article

References (24)

1. Sheldon WR, Blum J, Vogel JP, Souza JP, Gülmezoglu AM, Winikoff B,. Postpartum haemorrhage management, risks, and maternal outcomes: findings from the World Health Organization Multicountry Survey on Maternal and Newborn Health. BJOG 2014; 121 (Suppl. 1): 5-13.
2. WHO Recommendations for the Prevention and Treatment of Postpartum Haemorrhage. WHO PRESS: World Health Organization, 2012.
3. Bateman BT, Berman MF, Riley LE, Leffert LR,. The epidemiology of postpartum hemorrhage in a large, nationwide sample of deliveries. Anesth Analg 2010; 110: 1368-73.
4. Why Mothers Die. Report on Confidential Enquiries into Maternal Deaths, 1997-9. Royal London: College of Obstetricians and Gynaecologists, 2001.
5. Carvalho JC, Balki M, Kingdom J, Windrim R,. Oxytocin requirements at elective cesarean delivery: a dose-finding study. Obstet Gynocol 2004; 104: 1005-10.
6. Balki M, Ronayne M, Davies S, Fallah S, Kingdom J, Windrim R, Carvalho JC,. Minimum oxytocin dose requirement after cesarean delivery for labor arrest. Obstet Gynecol 2006; 107: 45-50.
7. Sartain JB, Barry JJ, Howat PW, McCormack DI, Bryant M,. Intravenous oxytocin bolus of 2 units is superior to 5 units during caesarian section. Br J Anaesth 2008; 101: 822-6.
8. Sarna MC, Soni AK, Gomez M, Oriol NE,. Intravenous oxytocin in patients undergoing elective cesarean section. Anesth Analg 1997; 84: 753-6.
9. Maycock EJ, Russell WC,. Anaphylactoid Reaction to Syntocinon. Anaesth Intens Care 1993; 21: 211-2.
10. Morriss WW, La Vies NG, Anderson SK, Southgate HJ,. Acute respiratory distress during Caesarean section under spinal anasthesia. Anaesthesia 1994; 49: 41-3.
11. Slater RM, Bowles BJM, Pumphrey RSH,. Anaphylactoid reaction to oxytocin in pregnancy. Anaesthesia 1985; 40: 655-6.
12. http://www.gynobsguideline.dk/files/postpartum-bloedning.pdf (last accessed 24 March 2015).
13. http://www.dasaim.dk/wp-content/uploads/2014/10/Anaestesi-til-kejsersnit1.pdf (last accessed 24 March 2015).
14. http://pro.medicin.dk/Medicin/Praeparater/397 (last accessed 24 March 2015).
15. Dyer RA, Butwick AJ, Carvalho B,. Oxytocin for labour and caesarean delivery: implications for the anaesthesiologist. Curr Opin Anaesth 2011; 24: 255-61.
16. Svanstöm MC, Biber B, Hanes M, Näslund U, Bålfors EM,. Signs of myocardial ischaemia after injection of oxytocin: a randomized double-blind comparison of oxytocin and methylergometrine during Caesarean section. Br J Anaesth 2008; 100: 683-9.
17. Thomas JS, Koh SH, Cooper GM,. Haemodynamic effects of oxytocin given as i.v. bolus or infusion on women undergoing Caesarean section. Br J Anaesth 2007; 98: 116-9.
18. Robinson C, Schumann R, Zhang P, Young RC,. Oxytocin-induced desensitization of the oxytocin receptor. Am J Obstet Gynocol 2003; 188: 497-502.
19. Johnsson M, Hanson U, Lidell C, Nordén-Lindeberg S,. ST depression at caesarean section and the relation to oxytocin dose. A randomised controlled trail. BJOG 2010; 117: 76-83.
20. Langesaeter E, Dragsund M, Rosseland LA,. Regional anaesthesia for Caesarian section in women with cardiac disease: a prospective study. Acta Anaesthesiol Scand 2010; 54: 46-54.
21. Tsen LC, Balki M,. Oxytocin protocols during cesarean delivery: time to acknowledge the rsik/benefit ratio? Int J Obstet Anesth 2010; 19: 243-5.
22. Bolton TJ, Randall K, Yentis SM,. Effects of the confidential enquiries into maternal deaths on the use of Syntocinon at caesarean section in the UK. Anaesthesia 2003; 58: 277-9.
23. West R, West S, Simons R, McGlennan A,. Impact of dose-finding studies on administration of oxytocin during caesarian section in the UK. Anaesthesia 2013; 68: 1021-5.
24. Liccardi G, Bilò M, Mauro C, Salzillo A, Piccolo A, D'Amato M, Liccardi A, D'Amato G,. Oxytocin: an unexpected risk for cardiologic and broncho-obstructive effects, and allergic reactions in susceptible delivering women. Multidiscip Respir Med 2013; 8: 67.