Cellular uptake and localization of polymyxins in renal tubular cells using rationally designed fluorescent probes

Antimicrobial Agents and Chemotherapy

Volumn 59, Issue 12, 2015, Pages 7489-7496

  Yun, Bo ^a   Azad, Mohammad A K ^a   Nowell, Cameron J ^a   Nation, Roger L ^a   Thompson, Philip E ^a   Roberts, Kade D ^a   Velkov, Tony ^a   Li, Jian ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

DANSYL CHLORIDE; FLUORESCENT DYE; POLYMYXIN B; ANTIINFECTIVE AGENT;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG DISTRIBUTION; DRUG LABELING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; ENDOPLASMIC RETICULUM; HYDROPHOBICITY; KIDNEY TUBULE CELL; MINIMUM INHIBITORY CONCENTRATION; MITOCHONDRION; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; ACINETOBACTER BAUMANNII; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINE; CHEMICAL PHENOMENA; DRUG EFFECTS; EPITHELIUM CELL; GROWTH, DEVELOPMENT AND AGING; KIDNEY TUBULE; KLEBSIELLA PNEUMONIAE; METABOLISM; MICROBIAL SENSITIVITY TEST; MOLECULAR IMAGING; PROCEDURES; PSEUDOMONAS AERUGINOSA; SYNTHESIS; TRANSPORT AT THE CELLULAR LEVEL; ULTRASTRUCTURE;

ACINETOBACTER BAUMANNII; ANIMALS; ANTI-BACTERIAL AGENTS; APOPTOSIS; BIOLOGICAL TRANSPORT; CELL LINE; DANSYL COMPOUNDS; DRUG DESIGN; ENDOPLASMIC RETICULUM; EPITHELIAL CELLS; FLUORESCENT DYES; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KIDNEY TUBULES; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TESTS; MITOCHONDRIA; MOLECULAR IMAGING; POLYMYXIN B; PSEUDOMONAS AERUGINOSA; RATS;

EID: 84954565592     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01216-15     Document Type: Article

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