Exome sequencing identifies potential novel candidate genes in patients with unexplained colorectal adenomatous polyposis

Familial Cancer

Volumn 15, Issue 2, 2016, Pages 281-288

  Spier, Isabel ^a   Kerick, Martin ^b,c   Drichel, Dmitriy ^d   Horpaopan, Sukanya ^a,e   Altmüller, Janine ^c,f   Laner, Andreas ^g,h   Holzapfel, Stefanie ^a   Peters, Sophia ^a   Adam, Ronja ^a   Zhao, Bixiao ⁱ   Becker, Tim ^a,d   Lifton, Richard P ⁱ   Holinski Feder, Elke ^g,h   Perner, Sven ^j,k   Thiele, Holger ^c   Nöthen, Markus M ^a   Hoffmann, Per ^a,l,m   Timmermann, Bernd ^b   Schweiger, Michal R ^b,c   Aretz, Stefan ^a  

^a UNIVERSITY OF BONN   (Germany)

^b MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^c UNIVERSITY OF COLOGNE   (Germany)

^d GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^e NARESUAN UNIVERSITY   (Thailand)

^f UNIVERSITY OF COLOGNE   (Germany)

^g LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^h Medizinisch Genetisches Zentrum   (Germany)

ⁱ YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^j UNIVERSITY HOSPITAL BONN   (Germany)

^k RESEARCH CENTER BORSTEL   (Germany)

^l UNIVERSITY HOSPITAL BASEL   (Switzerland)

^m UNIVERSITY OF BASEL   (Switzerland)

more..

Author keywords

Adenomatous polyposis; Candidate genes; Exome sequencing; Familial colorectal cancer; Hereditary tumor syndromes; Massive parallel sequencing

Indexed keywords

DNA; DESMOCOLLIN; DSC2 PROTEIN, HUMAN; ION CHANNEL; PIEZO1 PROTEIN, HUMAN;

ARTICLE; BIOINFORMATICS; CANCER PATIENT; CARCINOGENESIS; CLINICAL ARTICLE; COHORT ANALYSIS; COLORECTAL ADENOMA; CONTROLLED STUDY; COPY NUMBER VARIATION; DATA ANALYSIS; DSC2 GENE; EXOME; EXOME SEQUENCING; FAMILIAL COLON POLYPOSIS; GENE; GENE DELETION; GENE INSERTION; GENOME ANALYSIS; GERMLINE MUTATION; HIGH THROUGHPUT SEQUENCING; HUMAN; INHERITANCE; LEUKOCYTE; LOSS OF FUNCTION MUTATION; MISSENSE MUTATION; MULTIPLEX LIGATION DEPENDENT PROBE AMPLIFICATION; MUTATION RATE; PIEZO1 GENE; POINT MUTATION; PREDICTIVE VALUE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION; VALIDATION STUDY; ZSWIM7 GENE; ADENOMATOUS POLYP; AGED; COLON POLYPOSIS; FEMALE; GENETIC PREDISPOSITION; GENETICS; MALE; MIDDLE AGED; REPRODUCIBILITY;

ADENOMATOUS POLYPOSIS COLI; ADENOMATOUS POLYPS; AGED; DESMOCOLLINS; EXOME; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; ION CHANNELS; MALE; MIDDLE AGED; REPRODUCIBILITY OF RESULTS;

EID: 84954461873     PISSN: 13899600     EISSN: 15737292     Source Type: Journal    
DOI: 10.1007/s10689-016-9870-z     Document Type: Article

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