Abrogation of Age-Induced MicroRNA-195 Rejuvenates the Senescent Mesenchymal Stem Cells by Reactivating Telomerase

Stem Cells

Volumn 34, Issue 1, 2016, Pages 148-159

  Okada, Motoi ^a   Kim, Ha Won ^a   Matsu Ura, Kaoru ^a   Wang, Yi Gang ^a   Xu, Meifeng ^a   Ashraf, Muhammad ^a  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

Author keywords

Aging; Heart; miR 195; Stem cells; Telomerase

Indexed keywords

BETA GALACTOSIDASE; MICRORNA; MICRORNA 140; MICRORNA 146A; MICRORNA 146B; MICRORNA 195; PROTEIN KINASE B; SIRTUIN 1; TELOMERASE; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; MIRN195 MICRORNA, MOUSE;

3' UNTRANSLATED REGION; ACUTE HEART INFARCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL AGING; CELL PROLIFERATION; CELL REGENERATION; CONTROLLED STUDY; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; HEART INFARCTION SIZE; HEART LEFT VENTRICLE FUNCTION; LUCIFERASE ASSAY; MALE; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; REJUVENATION; SENESCENCE; TERT GENE; TRANSCRIPTION REGULATION; UPREGULATION; AGING; ANIMAL; C57BL MOUSE; CYTOLOGY; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; TREATMENT OUTCOME; WOUND HEALING;

AGING; ANIMALS; BASE SEQUENCE; BIOMARKERS; CELL AGING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE, INBRED C57BL; MICRORNAS; MOLECULAR SEQUENCE DATA; TELOMERASE; TREATMENT OUTCOME; UP-REGULATION; WOUND HEALING;

EID: 84954401115     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2211     Document Type: Article

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