-
1
-
-
84884378369
-
Synthesis of cholesterol analogs having varying length alkyl side chains including cholesterol-23, 23, 24, 24, 25, 26, 26, 26, 27, 27, 27-d(11) as probes of cholesterol's functions and properties
-
D.J. Baek, and R. Bittman Synthesis of cholesterol analogs having varying length alkyl side chains including cholesterol-23, 23, 24, 24, 25, 26, 26, 26, 27, 27, 27-d(11) as probes of cholesterol's functions and properties Chem. Phys. Lipids 175-176 2013 99 104 10.1016/j.chemphyslip.2013.08.003
-
(2013)
Chem. Phys. Lipids
, vol.175-176
, pp. 99-104
-
-
Baek, D.J.1
Bittman, R.2
-
2
-
-
60349119099
-
Sphingosine 1-phosphate lyase enzyme assay using a BODIPY-labeled substrate
-
P. Bandhuvula, Z. Li, R. Bittman, and J.D. Saba Sphingosine 1-phosphate lyase enzyme assay using a BODIPY-labeled substrate Biochem. Biophys. Res. Commun. 380 2009 366 370 10.1016/j.bbrc.2009.01.106
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.380
, pp. 366-370
-
-
Bandhuvula, P.1
Li, Z.2
Bittman, R.3
Saba, J.D.4
-
3
-
-
84941879088
-
LAPTM4B facilitates late endosomal ceramide export to control cell death pathways
-
T. Blom, S. Li, A. Dichlberger, N. Bäck, A.-H. Kim, U. Loizides-Mangold, H. Riezman, R. Bittman, and E. Ikonen LAPTM4B facilitates late endosomal ceramide export to control cell death pathways Nat. Chem. Biol. (Adv. Online Publ.) 2015 10.1038/nchembio.1889
-
(2015)
Nat. Chem. Biol. (Adv. Online Publ.)
-
-
Blom, T.1
Li, S.2
Dichlberger, A.3
Bäck, N.4
Kim, A.-H.5
Loizides-Mangold, U.6
Riezman, H.7
Bittman, R.8
Ikonen, E.9
-
4
-
-
77949394551
-
FTY720 stimulates 27-hydroxycholesterol production and confers atheroprotective effects in human primary macrophages
-
T. Blom, N. Bäck, A.-L. Mutka, R. Bittman, Z. Li, A. de Lera, P.T. Kovanen, U. Diczfalusy, and E. Ikonen FTY720 stimulates 27-hydroxycholesterol production and confers atheroprotective effects in human primary macrophages Circ. Res. 106 2010 720 729 10.1161/CIRCRESAHA.109.204396
-
(2010)
Circ. Res.
, vol.106
, pp. 720-729
-
-
Blom, T.1
Bäck, N.2
Mutka, A.-L.3
Bittman, R.4
Li, Z.5
De Lera, A.6
Kovanen, P.T.7
Diczfalusy, U.8
Ikonen, E.9
-
5
-
-
84865191217
-
Tracking sphingosine metabolism and transport in sphingolipidoses: NPC1 deficiency as a test case
-
T. Blom, Z. Li, R. Bittman, P. Somerharju, and E. Ikonen Tracking sphingosine metabolism and transport in sphingolipidoses: NPC1 deficiency as a test case Traffic 13 2012 1234 1243
-
(2012)
Traffic
, vol.13
, pp. 1234-1243
-
-
Blom, T.1
Li, Z.2
Bittman, R.3
Somerharju, P.4
Ikonen, E.5
-
6
-
-
78049483228
-
Selective deuterium labeling of the sphingoid backbone: Facile syntheses of 3,4,5-trideuterio-d-erythro-sphingosine and 3-deuterio-d-erythro-sphingomyelin
-
H.-S. Byun, and R. Bittman Selective deuterium labeling of the sphingoid backbone: facile syntheses of 3,4,5-trideuterio-d-erythro-sphingosine and 3-deuterio-d-erythro-sphingomyelin Chem. Phys. 163 2010 809 813 10.1016/j.chemphyslip.2010.09.001
-
(2010)
Chem. Phys.
, vol.163
, pp. 809-813
-
-
Byun, H.-S.1
Bittman, R.2
-
7
-
-
84856213807
-
Molecular recognition of a single sphingolipid species by a protein's transmembrane domain
-
F.-X. Contreras, A.M. Ernst, P. Haberkant, P. Björkholm, E. Lindahl, B. Gönen, C. Tischer, A. Elofsson, G. von Heijne, C. Thiele, R. Pepperkok, F. Wieland, and B. Brügger Molecular recognition of a single sphingolipid species by a protein's transmembrane domain Nature 481 2012 525 529 10.1038/nature10742
-
(2012)
Nature
, vol.481
, pp. 525-529
-
-
Contreras, F.-X.1
Ernst, A.M.2
Haberkant, P.3
Björkholm, P.4
Lindahl, E.5
Gönen, B.6
Tischer, C.7
Elofsson, A.8
Von Heijne, G.9
Thiele, C.10
Pepperkok, R.11
Wieland, F.12
Brügger, B.13
-
8
-
-
84875061571
-
Lipid exchange between Borrelia burgdorferi and host cells
-
J.T. Crowley, A.M. Toledo, T.J. LaRocca, J.L. Coleman, E. London, and J.L. Benach Lipid exchange between Borrelia burgdorferi and host cells PLoS Pathog. 9 2013 e1003109 10.1371/journal.ppat.1003109
-
(2013)
PLoS Pathog.
, vol.9
, pp. e1003109
-
-
Crowley, J.T.1
Toledo, A.M.2
LaRocca, T.J.3
Coleman, J.L.4
London, E.5
Benach, J.L.6
-
9
-
-
77953142003
-
Improvement in lipid and protein trafficking in Niemann-Pick C1 cells by correction of a secondary enzyme defect
-
C. Devlin, N.H. Pipalia, X. Liao, E.H. Schuchman, F.R. Maxfield, and I. Tabas Improvement in lipid and protein trafficking in Niemann-Pick C1 cells by correction of a secondary enzyme defect Traffic 11 2010 601 615 10.1111/j 1600-0854.2010.01046.x
-
(2010)
Traffic
, vol.11
, pp. 601-615
-
-
Devlin, C.1
Pipalia, N.H.2
Liao, X.3
Schuchman, E.H.4
Maxfield, F.R.5
Tabas, I.6
-
10
-
-
0026648695
-
Type C Niemann-Pick disease: A murine model of the lysosomal cholesterol lipidosis accumulates sphingosine and sphinganine in liver
-
E. Goldin, C.F. Roff, S.P. Miller, C. Rodriguez-Lafrasse, M.T. Vanier, R.O. Brady, and P.G. Pentchev Type C Niemann-Pick disease: a murine model of the lysosomal cholesterol lipidosis accumulates sphingosine and sphinganine in liver Biochim. Biophys. Acta 1127 1992 303 311
-
(1992)
Biochim. Biophys. Acta
, vol.1127
, pp. 303-311
-
-
Goldin, E.1
Roff, C.F.2
Miller, S.P.3
Rodriguez-Lafrasse, C.4
Vanier, M.T.5
Brady, R.O.6
Pentchev, P.G.7
-
11
-
-
38049098097
-
Protein-sphingolipid interactions within cellular membranes
-
P. Haberkant, O. Schmitt, F.-X. Contreras, C. Thiele, K. Hanada, H. Sprong, C. Reinhard, F.T. Wieland, and B. Brügger Protein-sphingolipid interactions within cellular membranes J. Lipid Res. 49 2008 251 262 10.1194/jlr.D700023-JLR200
-
(2008)
J. Lipid Res.
, vol.49
, pp. 251-262
-
-
Haberkant, P.1
Schmitt, O.2
Contreras, F.-X.3
Thiele, C.4
Hanada, K.5
Sprong, H.6
Reinhard, C.7
Wieland, F.T.8
Brügger, B.9
-
12
-
-
53849130991
-
BODIPY-cholesterol: A new tool to visualize sterol trafficking in living cells and organisms
-
M. Hölttä-Vuori, R.-L. Uronen, J. Repakova, E. Salonen, I. Vattulainen, P. Panula, Z. Li, R. Bittman, and E. Ikonen BODIPY-cholesterol: a new tool to visualize sterol trafficking in living cells and organisms Traffic 9 2008 1839 1849 10.1111/j 1600-0854.2008.00801.x
-
(2008)
Traffic
, vol.9
, pp. 1839-1849
-
-
Hölttä-Vuori, M.1
Uronen, R.-L.2
Repakova, J.3
Salonen, E.4
Vattulainen, I.5
Panula, P.6
Li, Z.7
Bittman, R.8
Ikonen, E.9
-
13
-
-
38549141572
-
Cellular cholesterol trafficking and compartmentalization
-
E. Ikonen Cellular cholesterol trafficking and compartmentalization Nat. Rev. Mol. Cell Biol. 9 2008 125 138 10.1038/nrm2336
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 125-138
-
-
Ikonen, E.1
-
14
-
-
84887615640
-
LDL cholesterol recycles to the plasma membrane via a Rab8a-Myosin5b-actin-dependent membrane transport route
-
K. Kanerva, R.L. Uronen, T. Blom, S. Li, R. Bittman, P. Lappalainen, J. Peränen, G. Raposo, and E. Ikonen LDL cholesterol recycles to the plasma membrane via a Rab8a-Myosin5b-actin-dependent membrane transport route Dev. Cell 27 2013 249 262
-
(2013)
Dev. Cell
, vol.27
, pp. 249-262
-
-
Kanerva, K.1
Uronen, R.L.2
Blom, T.3
Li, S.4
Bittman, R.5
Lappalainen, P.6
Peränen, J.7
Raposo, G.8
Ikonen, E.9
-
15
-
-
35548939515
-
Synthesis and spectral properties of cholesterol- and FTY720-containing boron dipyrromethene dyes
-
Z. Li, and R. Bittman Synthesis and spectral properties of cholesterol- and FTY720-containing boron dipyrromethene dyes J. Org. Chem. 72 2007 8376 8382 10.1021/jo701475q
-
(2007)
J. Org. Chem.
, vol.72
, pp. 8376-8382
-
-
Li, Z.1
Bittman, R.2
-
16
-
-
66349127425
-
Rab8 regulates ABCA1 cell surface expression and facilitates cholesterol efflux in primary human macrophages
-
M.D. Linder, M.I. Mäyränpää, J. Peränen, T.E. Pietilä, V.M. Pietiäinen, R.-L. Uronen, V.M. Olkkonen, P.T. Kovanen, and E. Ikonen Rab8 regulates ABCA1 cell surface expression and facilitates cholesterol efflux in primary human macrophages Arterioscler. Thromb. Vasc. Biol. 29 2009 883 888 10.1161/ATVBAHA.108.179481
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, pp. 883-888
-
-
Linder, M.D.1
Mäyränpää, M.I.2
Peränen, J.3
Pietilä, T.E.4
Pietiäinen, V.M.5
Uronen, R.-L.6
Olkkonen, V.M.7
Kovanen, P.T.8
Ikonen, E.9
-
17
-
-
33846089323
-
Rab8-dependent recycling promotes endosomal cholesterol removal in normal and sphingolipidosis cells
-
M.D. Linder, R.-L. Uronen, M. Hölttä-Vuori, P. van der Sluijs, J. Peränen, and E. Ikonen Rab8-dependent recycling promotes endosomal cholesterol removal in normal and sphingolipidosis cells Mol. Biol. Cell 18 2007 47 56 10.1091/mbc.E06-07-0575
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 47-56
-
-
Linder, M.D.1
Uronen, R.-L.2
Hölttä-Vuori, M.3
Van Der Sluijs, P.4
Peränen, J.5
Ikonen, E.6
-
18
-
-
40449112030
-
Fluorescent detection of lipid droplets and associated proteins
-
(Chapter 24), Unit 24.2
-
L.L. Listenberger, and D.A. Brown Fluorescent detection of lipid droplets and associated proteins Curr. Protoc. Cell Biol. 2007 10.1002/0471143030 cb2402s35 (Chapter 24), Unit 24.2
-
(2007)
Curr. Protoc. Cell Biol.
-
-
Listenberger, L.L.1
Brown, D.A.2
-
19
-
-
55549134611
-
Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium
-
E. Lloyd-Evans, A.J. Morgan, X. He, D.A. Smith, E. Elliot-Smith, D.J. Sillence, G.C. Churchill, E.H. Schuchman, A. Galione, and F.M. Platt Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium Nat. Med. 14 2008 1247 1255 10.1038/nm.1876
-
(2008)
Nat. Med.
, vol.14
, pp. 1247-1255
-
-
Lloyd-Evans, E.1
Morgan, A.J.2
He, X.3
Smith, D.A.4
Elliot-Smith, E.5
Sillence, D.J.6
Churchill, G.C.7
Schuchman, E.H.8
Galione, A.9
Platt, F.M.10
-
20
-
-
0042839476
-
Total synthesis of two photoactivatable analogues of the growth-factor-like mediator sphingosine 1-phosphate: Differential interaction with protein targets
-
X. Lu, S. Cseh, H.-S. Byun, G. Tigyi, and R. Bittman Total synthesis of two photoactivatable analogues of the growth-factor-like mediator sphingosine 1-phosphate: differential interaction with protein targets J. Org. Chem. 68 2003 7046 7050 10.1021/jo034828q
-
(2003)
J. Org. Chem.
, vol.68
, pp. 7046-7050
-
-
Lu, X.1
Cseh, S.2
Byun, H.-S.3
Tigyi, G.4
Bittman, R.5
-
21
-
-
84875873877
-
Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice
-
C. Martel, W. Li, B. Fulp, A.M. Platt, E.L. Gautier, M. Westerterp, R. Bittman, A.R. Tall, S.-H. Chen, M.J. Thomas, D. Kreisel, M.A. Swartz, M.G. Sorci-Thomas, and G.J. Randolph Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice J. Clin. Invest. 123 2013 1571 1579 10.1172/JCI63685
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 1571-1579
-
-
Martel, C.1
Li, W.2
Fulp, B.3
Platt, A.M.4
Gautier, E.L.5
Westerterp, M.6
Bittman, R.7
Tall, A.R.8
Chen, S.-H.9
Thomas, M.J.10
Kreisel, D.11
Swartz, M.A.12
Sorci-Thomas, M.G.13
Randolph, G.J.14
-
22
-
-
84910008356
-
Enzymatic oxidation of cholesterol: Properties and functional effects of cholestenone in cell membranes
-
M. Neuvonen, M. Manna, S. Mokkila, M. Javanainen, T. Rog, Z. Liu, R. Bittman, I. Vattulainen, and E. Ikonen Enzymatic oxidation of cholesterol: properties and functional effects of cholestenone in cell membranes PLoS One 9 2014 e103743 10.1371/journal.pone.0103743
-
(2014)
PLoS One
, vol.9
, pp. e103743
-
-
Neuvonen, M.1
Manna, M.2
Mokkila, S.3
Javanainen, M.4
Rog, T.5
Liu, Z.6
Bittman, R.7
Vattulainen, I.8
Ikonen, E.9
-
23
-
-
33847675759
-
Synthesis of borondipyrromethene (BODIPY)-labeled sphingosine derivatives by cross-metathesis reaction
-
C. Peters, A. Billich, M. Ghobrial, K. Högenauer, T. Ullrich, and P. Nussbaumer Synthesis of borondipyrromethene (BODIPY)-labeled sphingosine derivatives by cross-metathesis reaction J. Org. Chem. 72 2007 1842 1845 10.1021/jo062347b
-
(2007)
J. Org. Chem.
, vol.72
, pp. 1842-1845
-
-
Peters, C.1
Billich, A.2
Ghobrial, M.3
Högenauer, K.4
Ullrich, T.5
Nussbaumer, P.6
-
24
-
-
84883284087
-
NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation
-
V. Pietiäinen, B. Vassilev, T. Blom, W. Wang, J. Nelson, R. Bittman, N. Bäck, N. Zelcer, and E. Ikonen NDRG1 functions in LDL receptor trafficking by regulating endosomal recycling and degradation J. Cell Sci. 126 2013 3961 3971 10.1242/jcs.128132
-
(2013)
J. Cell Sci.
, vol.126
, pp. 3961-3971
-
-
Pietiäinen, V.1
Vassilev, B.2
Blom, T.3
Wang, W.4
Nelson, J.5
Bittman, R.6
Bäck, N.7
Zelcer, N.8
Ikonen, E.9
-
25
-
-
84926293921
-
Emerging biology of sphingosine-1-phosphate: Its role in pathogenesis and therapy
-
R.L. Proia, and T. Hla Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy J. Clin. Invest. 125 2015 1379 1387 10.1172/JCI76369
-
(2015)
J. Clin. Invest.
, vol.125
, pp. 1379-1387
-
-
Proia, R.L.1
Hla, T.2
-
26
-
-
0028334261
-
Free sphingoid bases in tissues from patients with type C Niemann-Pick disease and other lysosomal storage disorders
-
C. Rodriguez-Lafrasse, R. Rousson, P.G. Pentchev, P. Louisot, and M.T. Vanier Free sphingoid bases in tissues from patients with type C Niemann-Pick disease and other lysosomal storage disorders Biochim. Biophys. Acta 1226 1994 138 144
-
(1994)
Biochim. Biophys. Acta
, vol.1226
, pp. 138-144
-
-
Rodriguez-Lafrasse, C.1
Rousson, R.2
Pentchev, P.G.3
Louisot, P.4
Vanier, M.T.5
-
27
-
-
84863034220
-
Combined light and electron microscopy using diaminobenzidine photooxidation to monitor trafficking of lipids derived from lipoprotein particles
-
C. Röhrl, C. Meisslitzer-Ruppitsch, R. Bittman, Z. Li, G. Pabst, R. Prassl, W. Strobl, J. Neumüller, A. Ellinger, M. Pavelka, and H. Stangl Combined light and electron microscopy using diaminobenzidine photooxidation to monitor trafficking of lipids derived from lipoprotein particles Curr. Pharm. Biotechnol. 13 2012 331 340
-
(2012)
Curr. Pharm. Biotechnol.
, vol.13
, pp. 331-340
-
-
Röhrl, C.1
Meisslitzer-Ruppitsch, C.2
Bittman, R.3
Li, Z.4
Pabst, G.5
Prassl, R.6
Strobl, W.7
Neumüller, J.8
Ellinger, A.9
Pavelka, M.10
Stangl, H.11
-
28
-
-
81855206679
-
A sensitive assay for ABCA1-mediated cholesterol efflux using BODIPY-cholesterol
-
S. Sankaranarayanan, G. Kellner-Weibel, M. de la Llera-Moya, M.C. Phillips, B.F. Asztalos, R. Bittman, and G.H. Rothblat A sensitive assay for ABCA1-mediated cholesterol efflux using BODIPY-cholesterol J. Lipid Res. 52 2011 2332 2340 10.1194/jlr.D018051
-
(2011)
J. Lipid Res.
, vol.52
, pp. 2332-2340
-
-
Sankaranarayanan, S.1
Kellner-Weibel, G.2
De La Llera-Moya, M.3
Phillips, M.C.4
Asztalos, B.F.5
Bittman, R.6
Rothblat, G.H.7
-
29
-
-
33645967519
-
Correlated fluorescence-atomic force microscopy of membrane domains: Structure of fluorescence probes determines lipid localization
-
J.E. Shaw, R.F. Epand, R.M. Epand, Z. Li, R. Bittman, and C.M. Yip Correlated fluorescence-atomic force microscopy of membrane domains: structure of fluorescence probes determines lipid localization Biophys. J. 90 2006 2170 2178 10.1529/biophysj.105.073510
-
(2006)
Biophys. J.
, vol.90
, pp. 2170-2178
-
-
Shaw, J.E.1
Epand, R.F.2
Epand, R.M.3
Li, Z.4
Bittman, R.5
Yip, C.M.6
-
30
-
-
84893617361
-
Human endothelial progenitor cells internalize high-density lipoprotein
-
K. Srisen, C. Röhrl, C. Meisslitzer-Ruppitsch, C. Ranftler, A. Ellinger, M. Pavelka, and J. Neumüller Human endothelial progenitor cells internalize high-density lipoprotein PLoS One 8 2013 e83189 10.1371/journal.pone.0083189
-
(2013)
PLoS One
, vol.8
, pp. e83189
-
-
Srisen, K.1
Röhrl, C.2
Meisslitzer-Ruppitsch, C.3
Ranftler, C.4
Ellinger, A.5
Pavelka, M.6
Neumüller, J.7
-
31
-
-
32044475128
-
Niemann-Pick type C disease: Novel NPC1 mutations and characterization of the concomitant acid sphingomyelinase deficiency
-
H. Tamura, T. Takahashi, N. Ban, H. Torisu, H. Ninomiya, G. Takada, and N. Inagaki Niemann-Pick type C disease: novel NPC1 mutations and characterization of the concomitant acid sphingomyelinase deficiency Mol. Genet. 87 2006 113 121 10.1016/j.ymgme.2005.07.025
-
(2006)
Mol. Genet.
, vol.87
, pp. 113-121
-
-
Tamura, H.1
Takahashi, T.2
Ban, N.3
Torisu, H.4
Ninomiya, H.5
Takada, G.6
Inagaki, N.7
-
32
-
-
84864401578
-
Visualization of lipid metabolism in the zebrafish intestine reveals a relationship between NPC1L1-mediated cholesterol uptake and dietary fatty acid
-
J.W. Walters, J.L. Anderson, R. Bittman, M. Pack, and S.A. Farber Visualization of lipid metabolism in the zebrafish intestine reveals a relationship between NPC1L1-mediated cholesterol uptake and dietary fatty acid Chem. Biol. 19 2012 913 925 10.1016/j.chembiol.2012.05.018
-
(2012)
Chem. Biol.
, vol.19
, pp. 913-925
-
-
Walters, J.W.1
Anderson, J.L.2
Bittman, R.3
Pack, M.4
Farber, S.A.5
|