Rab8 regulates ABCA1 cell surface expression and facilitates cholesterol efflux in primary human macrophages

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 29, Issue 6, 2009, Pages 883-888

  Linder, Matts D ^a   Mäyränpää, Mikko I ^a,b   Peränen, Johan ^c   Pietilä, Taija E ^b   Pietiäinen, Vilja M ^a   Uronen, Riikka Liisa ^a   Olkkonen, Vesa M ^d   Kovanen, Petri T ^d   Ikonen, Elina ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b WIHURI RESEARCH INSTITUTE   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

Apolipoprotein A I; ATP binding cassette transporter; Foam cell; Rab GTPase

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN A1; BETA1 INTEGRIN; CHOLESTEROL; GUANOSINE TRIPHOSPHATASE; LIPID; LIPOPROTEIN; PROTEIN RAB8; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG; ABC TRANSPORTER; APOA1 PROTEIN, HUMAN; RAB PROTEIN; RAB8A PROTEIN, HUMAN; SMALL INTERFERING RNA;

ADENOVIRUS; ARTICLE; ATHEROSCLEROSIS; CELL MEMBRANE; CELL ORGANELLE; CELL SURFACE; CONTROLLED STUDY; ENDOSOME; FIBROBLAST; FOAM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MACROPHAGE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; UPREGULATION; CELL CULTURE; CORONARY ARTERY DISEASE; GENETIC TRANSFECTION; GENETICS; METABOLISM; PROTEIN TRANSPORT; RNA INTERFERENCE; TRANSPORT AT THE CELLULAR LEVEL;

APOLIPOPROTEIN A-I; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CELL MEMBRANE; CELLS, CULTURED; CHOLESTEROL; CORONARY ARTERY DISEASE; ENDOSOMES; FOAM CELLS; HUMANS; PROTEIN TRANSPORT; RAB GTP-BINDING PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 66349127425     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.108.179481     Document Type: Article

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