Nucleoapzymes: Hemin/G-Quadruplex DNAzyme-Aptamer Binding Site Conjugates with Superior Enzyme-like Catalytic Functions

Journal of the American Chemical Society

Volumn 138, Issue 1, 2016, Pages 164-172

  Golub, Eyal ^a   Albada, H Bauke ^a   Liao, Wei Ching ^a   Biniuri, Yonatan ^a   Willner, Itamar ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYSIS; MOLECULAR DYNAMICS; NUCLEIC ACIDS; OXIDATION;

APTAMER SEQUENCES; CATALYTIC FUNCTIONS; DNA RECOGNITION; ENHANCED CATALYTIC ACTIVITY; HYBRID STRUCTURE; MOLECULAR DYNAMICS SIMULATIONS; NOVEL CONCEPT; SATURATION KINETICS;

CATALYST ACTIVITY;

APTAMER; ARGININE; CITRULLINE; DEOXYRIBOZYME; DOPA; DOPAMINE; GUANINE QUADRUPLEX; HEMIN; HYDROGEN PEROXIDE; LEVODOPA; NUCLEOAPZYME; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CATALYST; CONJUGATION; ENZYME ACTIVITY; ENZYME ISOLATION; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBSTRATE; HYBRID; KINETIC PARAMETERS; MOLECULAR DYNAMICS; NUCLEOTIDE BINDING SITE; OXIDATION; PROTEIN FUNCTION; BINDING SITE; CHEMISTRY;

APTAMERS, NUCLEOTIDE; BINDING SITES; CATALYSIS; DNA, CATALYTIC; G-QUADRUPLEXES; HEMIN;

EID: 84954348630     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b09457     Document Type: Article

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