Real-time quaking-induced conversion analysis for the diagnosis of sporadic creutzfeldt-jakob disease in Korea

Journal of Clinical Neurology (Korea)

Volumn 12, Issue 1, 2016, Pages 101-106

  Park, Jeong Ho ^a   Choi, Yeong Gon ^a   Lee, Yun Jung ^a   Park, Seok Joo ^a   Choi, Hong Seok ^a   Choi, Kyung Chan ^a,b   Choi, Eun Kyoung ^a   Kim, Yong Sun ^a  

^a Hallym University   (South Korea)

^b Hallym University College of Medicine   (South Korea)

Author keywords

14 3 3; Cerebrospinal fluid; Creutzfeldt Jakob disease; RT QuIC; Total tau protein

Indexed keywords

EID: 84954317712     PISSN: 17386586     EISSN: 20055013     Source Type: Journal    
DOI: 10.3988/jcn.2016.12.1.101     Document Type: Article

References (17)

1. Kübler E, Oesch B, Raeber AJ. Diagnosis of prion diseases. Br Med Bull 2003;66:267-279.
2. Yang TI, Jung DS, Ahn BY, Jeong BH, Cho HJ, Kim YS, et al. Familial Creutzfeldt-Jakob disease with V180I mutation. J Korean Med Sci 2010;25:1097-1100.
3. Tschampa HJ, Zerr I, Urbach H. Radiological assessment of Creutzfeldt-Jakob disease. Eur Radiol 2007;17:1200-1211.
4. Shimada T, Fournier AE, Yamagata K. Neuroprotective function of 14-3-3 proteins in neurodegeneration. Biomed Res Int 2013;2013: 564534.
5. Stoeck K, Sanchez-Juan P, Gawinecka J, Green A, Ladogana A, Poc- chiari M, et al. Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt-Jakob disease and rapid dementias: a longitudinal multi- centre study over 10 years. Brain 2012;135(Pt 10):3051-3061.
6. Aguzzi A, Heikenwalder M, Miele G. Progress and problems in the biology, diagnostics, and therapeutics of prion diseases. J Clin Invest 2004;114:153-160.
7. Cramm M, Schmitz M, Karch A, Zafar S, Varges D, Mitrova E, et al. Characteristic CSF prion seeding efficiency in humans with prion diseases. Mol Neurobiol 2015;51:396-405.
8. Orrù CD, Wilham JM, Vascellari S, Hughson AG, Caughey B. New generation QuIC assays for prion seeding activity. Prion 2012;6:147-152.
9. Peden AH, McGuire LI, Appleford NE, Mallinson G, Wilham JM, Orrú CD, et al. Sensitive and specific detection of sporadic Creutzfeldt- Jakob disease brain prion protein using real-time quaking-induced conversion. J Gen Virol 2012;93(Pt 2):438-449.
10. LeVine H 3rd. Quantification of beta-sheet amyloid fibril structures with thioflavin T. Methods Enzymol 1999;309:274-284.
11. Atarashi R, Satoh K, Sano K, Fuse T, Yamaguchi N, Ishibashi D, et al. Ultrasensitive human prion detection in cerebrospinal fluid by realtime quaking-induced conversion. Nat Med 2011;17:175-178.
12. Atarashi R, Sano K, Satoh K, Nishida N. Real-time quaking-induced conversion: a highly sensitive assay for prion detection. Prion 2011;5: 150-153.
13. Jeong BH, Nam JH, Lee YJ, Lee KH, Jang MK, Carp RI, et al. Polymorphisms of the prion protein gene (PRNP) in a Korean population. J Hum Genet 2004;49:319-324.
14. Skillbäck T, Rosén C, Asztely F, Mattsson N, Blennow K, Zetterberg H. Diagnostic performance of cerebrospinal fluid total tau and phosphorylated tau in Creutzfeldt-Jakob disease: results from the Swedish Mortality Registry. JAMA Neurol 2014;71:476-483.
15. Sano K, Satoh K, Atarashi R, Takashima H, Iwasaki Y, Yoshida M, et al. Early detection of abnormal prion protein in genetic human prion diseases now possible using real-time QUIC assay. PLoS One 2013;8: e54915.
16. Orrú CD, Bongianni M, Tonoli G, Ferrari S, Hughson AG, Grove- man BR, et al. A test for Creutzfeldt-Jakob disease using nasal brushings. N Engl J Med 2014;371:519-529.
17. Orrú CD, Groveman BR, Hughson AG, Zanusso G, Coulthart MB, Caughey B. Rapid and sensitive RT-QuIC detection of human Creutzfeldt-Jakob disease using cerebrospinal fluid. MBio 2015;6(1). pii: e02451-14.