25-Hydroxyvitamin D assays: Potential interference from other circulating vitamin D metabolites

Journal of Steroid Biochemistry and Molecular Biology

Volumn 164, Issue , 2016, Pages 134-138

  Carter, G D ^a   Jones, J C ^a   Shannon, J ^a   Williams, E L ^a   Jones, G ^b   Kaufmann, M ^b   Sempos, C ^c  

^a CHARING CROSS HOSPITAL   (United Kingdom)

^b QUEEN S UNIVERSITY   (Canada)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

24,25 Dihydroxyvitamin D; 25 Hydroxyvitamin D; 3 epi 25 Hydroxyvitamin D; DEQAS; Interference

Indexed keywords

24,25 DIHYDROXYVITAMIN D; 25 HYDROXYVITAMIN D; 3 EPI 25 HYDROXYVITAMIN D; UNCLASSIFIED DRUG; 25-HYDROXYVITAMIN D; CALCIFEDIOL; SECALCIFEROL; VITAMIN D;

CROSS REACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIQUID CHROMATOGRAPHY; MEASUREMENT ACCURACY; PROTEIN BINDING; RECEPTOR BINDING ASSAY; REVIEW; TANDEM MASS SPECTROMETRY; ULTRAVIOLET RADIATION; ULTRAVIOLET SPECTROPHOTOMETRY; ANALOGS AND DERIVATIVES; BLOOD; IMMUNOASSAY; METABOLISM; PROCEDURES; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM;

24,25-DIHYDROXYVITAMIN D 3; CALCIFEDIOL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; IMMUNOASSAY; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM; TANDEM MASS SPECTROMETRY; VITAMIN D;

EID: 84954305895     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2015.12.018     Document Type: Review

References (10)

1. 2 in human serum using isotope-dilution liquid chromatography–tandem mass spectrometry. Anal. Chem. 82 (2010), 1942–1948.
2. [2] Cashman, K.D., Hayes, A., Galvin, K., Merkel, J., Jones, G., Kaufmann, M., Hoofnagle, A.N., Carter, G.D., Durazo-Arvizu, R.A., Sempos, C.T., Significance of serum 24,25-dihydroxyvitamin D in the assessment of vitamin D status: a double-edged sword?. Clin. Chem. 61 (2015), 636–645.
3. [3] Couchman, L., Benton, C.M., Moniz, C.F., Variability in the analysis of 25-hydroxyvitamin D by liquid chromatography–tandem mass spectrometry: the devil is in the detail. Clin. Chim. Acta 413 (2012), 1239–1243.
4. [4] Kaufmann, M., Gallagher, C., Peacock, M., Schlingmann, K.-P., Konrad, M., DeLuca, H.F., Sigueiro, R., Lopez, B., Mourino, A., Maestro, M., St-Arnaud, R., Finkelstein, J., Cooper, D.P., Jones, G., clinical utility of simultaneous quantitation of 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D by LC–MS/MS involving derivatization with DMEQ-TAD. J. Clin. Endocrinol. Metab. 99 (2014), 2567–2574.
5. [5] Singh, R.J., Taylor, R.L., Reddy, G.S., Grebe, S.K., C-3 epimers can account for a significant proportion of total circulating 25-hydroxyvitamin D in infants, complicating accurate measurement and interpretation of vitamin D status. J. Clin. Endocrinol. Metab. 91 (2006), 3055–3061.
6. 3 is present in adult serum. J. Clin. Endocrinol. Metab. 97 (2012), 163–168.
7. [7] Strathmann, F.G., Sadilkova, K., Laha, T.J., LeSourd, S.E., Bornhorst, J.A., Hoofnagle, A.N., Jack, R., 3-epi-25 hydroxyvitamin D concentrations are not correlated with age in a cohort of infants and adult. Clin. Chim. Acta. 413 (2012), 203–206.
8. 3 cross-reactivity in the Roche Elecsys vitamin D Total protein binding assay. Clin. Chem. Lab. Med. 52 (2014), 373–380.
9. 2 while on high-dose ergocalciferol. J. Clin. Endocrinol. Metab. 99 (2014), 1117–1121.
10. [10] Carter, G.D., Jones, J.C., Berry, J.L., The anomalous behaviour of exogenous 25-hydroxyvitamin D in competitive binding assays. J. Steroid Biochem. Mol. Biol. 103 (2007), 480–482.