-
1
-
-
33947581390
-
The impact of translocation and gene fusions on cancer causation
-
Mitelman, F., Johansson, B. & Mertens, F. The impact of translocation and gene fusions on cancer causation. Nat. Rev. Cancer 7, 233-245 (2007).
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 233-245
-
-
Mitelman, F.1
Johansson, B.2
Mertens, F.3
-
2
-
-
79960847016
-
Advances in sarcoma genomics and new therapeutic targets
-
Taylor, B. S. et al. Advances in sarcoma genomics and new therapeutic targets. Nat. Rev. Cancer 11, 541-557 (2011).
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 541-557
-
-
Taylor, B.S.1
-
3
-
-
0028950996
-
A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination
-
Smith, A. J. H. et al. A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination. Nat. Genet. 9, 376-385 (1995).
-
(1995)
Nat. Genet.
, vol.9
, pp. 376-385
-
-
Smith, A.J.H.1
-
4
-
-
0029119145
-
Cre-mediated sitespecific translocation between nonhomologous mouse chromosomes
-
Van Deursen, J., Fornerod, M., van Rees, B. & Grosveld, G. Cre-mediated sitespecific translocation between nonhomologous mouse chromosomes. Proc. Natl. Acad. Sci. USA 92, 7376-7380 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7376-7380
-
-
Van Deursen, J.1
Fornerod, M.2
Van Rees, B.3
Grosveld, G.4
-
5
-
-
0345582392
-
Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer
-
Forster, A. et al. Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer. Cancer Cell 3, 449-458 (2003).
-
(2003)
Cancer Cell
, vol.3
, pp. 449-458
-
-
Forster, A.1
-
6
-
-
0026686674
-
Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours
-
Delattre, O. et al. Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature 359, 162-165 (1992).
-
(1992)
Nature
, vol.359
, pp. 162-165
-
-
Delattre, O.1
-
7
-
-
0028307384
-
A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG
-
Sorensen, P. H. et al. A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG. Nat. Genet. 6, 146-151 (1994).
-
(1994)
Nat. Genet.
, vol.6
, pp. 146-151
-
-
Sorensen, P.H.1
-
8
-
-
70349753195
-
Advances in Ewing's sarcoma research: Where are we now and what lies ahead?
-
Ordonez, J. L., Osuna, D.,Herrero, D., deAlava, E.&Madoz-Gurpide, J. Advances in Ewing's sarcoma research: where are we now and what lies ahead? Cancer Res. 69, 7140-7150 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 7140-7150
-
-
Ordonez, J.L.1
Osuna, D.2
Herrero, D.3
DeAlava, E.4
Madoz-Gurpide, J.5
-
9
-
-
36048942033
-
EWS/FLI-1 induces rapid onset of myeloid/erythroid leukemia in mice
-
Torchia, E. C., Boyd, K., Rehg, J. E., Qu, C. & Baker, S. J. EWS/FLI-1 induces rapid onset of myeloid/erythroid leukemia in mice. Mol. Cell. Biol. 27, 7918-7934 (2007).
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 7918-7934
-
-
Torchia, E.C.1
Boyd, K.2
Rehg, J.E.3
Qu, C.4
Baker, S.J.5
-
10
-
-
0027438827
-
Combinatorial generation of variable fusion proteins in the Ewing family of tumours
-
Zucman, J. et al. Combinatorial generation of variable fusion proteins in the Ewing family of tumours. EMBO J. 12, 4481-4487 (1993).
-
(1993)
EMBO J.
, vol.12
, pp. 4481-4487
-
-
Zucman, J.1
-
11
-
-
34548446433
-
Sarcomas: Genetics, signaling, and cellular origins. Part I: The fellowship of TET
-
Riggi, N., Cironi, L., Suva, M. L. & Stamenkovic, I. Sarcomas: genetics, signaling, and cellular origins. Part I: The fellowship of TET. J. Pathol. 213, 4-20 (2007).
-
(2007)
J. Pathol.
, vol.213
, pp. 4-20
-
-
Riggi, N.1
Cironi, L.2
Suva, M.L.3
Stamenkovic, I.4
-
12
-
-
33744548947
-
Dilated cardiomyopathy resulting from high-level myocardial expression of Cre-recombinase
-
Buerger, A. et al. Dilated cardiomyopathy resulting from high-level myocardial expression of Cre-recombinase. J. Card. Fail. 12, 392-398 (2006).
-
(2006)
J. Card. Fail.
, vol.12
, pp. 392-398
-
-
Buerger, A.1
-
13
-
-
0034252206
-
Interchromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development
-
Collins, E. C., Pannell, R., Simpson, E. M., Forster, A. & Rabbitts, T. H. Interchromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development. EMBO Rep. 1, 127-132 (2000).
-
(2000)
EMBO Rep.
, vol.1
, pp. 127-132
-
-
Collins, E.C.1
Pannell, R.2
Simpson, E.M.3
Forster, A.4
Rabbitts, T.H.5
-
14
-
-
27144493049
-
Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reasignment in tumorigenesis
-
Drynan, L. F. et al. Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reasignment in tumorigenesis. EMBO J. 24, 3136-3146 (2005).
-
(2005)
EMBO J.
, vol.24
, pp. 3136-3146
-
-
Drynan, L.F.1
-
15
-
-
0034252564
-
Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP-mediated recombination in the mouse
-
Buchholz, F., Regaeli, Y., Trumpp, A. & Bishop, J. M. Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP-mediated recombination in the mouse. EMBO Rep. 11, 133-139 (2000).
-
(2000)
EMBO Rep.
, vol.11
, pp. 133-139
-
-
Buchholz, F.1
Regaeli, Y.2
Trumpp, A.3
Bishop, J.M.4
-
16
-
-
84903786142
-
Ewing's sarcoma precursors are highly enriched in embryonic osteochondrogenic progenitors
-
Tanaka, M. et al. Ewing's sarcoma precursors are highly enriched in embryonic osteochondrogenic progenitors. J. Clin. Invest. 121, 3061-3074 (2014).
-
(2014)
J. Clin. Invest.
, vol.121
, pp. 3061-3074
-
-
Tanaka, M.1
-
17
-
-
0033136001
-
GDF5 coordinates bone and joint formation during digit development
-
Storm, E. E.& Kingsley, D. M. GDF5 coordinates bone and joint formation during digit development. Dev. Biol. 209, 11-27 (1999).
-
(1999)
Dev. Biol.
, vol.209
, pp. 11-27
-
-
Storm, E.E.1
Kingsley, D.M.2
-
18
-
-
84867242355
-
Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis
-
Vijayaraj, P. et al. Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis. Development 139, 3973-3985 (2012).
-
(2012)
Development
, vol.139
, pp. 3973-3985
-
-
Vijayaraj, P.1
-
19
-
-
0035845859
-
Loss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation
-
Deneen, B. & Denny, C. T. Loss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation. Oncogene 20, 6731-6741 (2001).
-
(2001)
Oncogene
, vol.20
, pp. 6731-6741
-
-
Deneen, B.1
Denny, C.T.2
-
20
-
-
0036560740
-
The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts
-
Lessnick, S. L., Dacwag, C. S. & Golub, T. R. The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts. Cancer Cell 1, 393-401 (2002).
-
(2002)
Cancer Cell
, vol.1
, pp. 393-401
-
-
Lessnick, S.L.1
Dacwag, C.S.2
Golub, T.R.3
-
21
-
-
76249124341
-
EWS/FLI1 oncogene activates caspase 3 transcription and triggers apoptosis in vivo
-
Sohn, E. J. et al. EWS/FLI1 oncogene activates caspase 3 transcription and triggers apoptosis in vivo. Cancer Res. 70, 1154-1163 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 1154-1163
-
-
Sohn, E.J.1
-
22
-
-
66049145239
-
Marinobufagenin induces increases in procollagen expression in a process involving protein kinase C and Fli-1: Implications for uremic cardiomyopathy
-
Elkareh, J. et al. Marinobufagenin induces increases in procollagen expression in a process involving protein kinase C and Fli-1: implications for uremic cardiomyopathy. Am. J. Physiol. Renal. Physiol. 296, F1219-F1226 (2009).
-
(2009)
Am. J. Physiol. Renal. Physiol.
, vol.296
, pp. F1219-F1226
-
-
Elkareh, J.1
-
23
-
-
33847261472
-
Re-employment of developmental transcription factors in adult heart disease
-
Oka, T., Xu, J. &Molkentin, J. D. Re-employment of developmental transcription factors in adult heart disease. Semin. Cell Dev. Biol. 18, 117-131 (2007).
-
(2007)
Semin. Cell Dev. Biol.
, vol.18
, pp. 117-131
-
-
Oka, T.1
Xu, J.2
Molkentin, J.D.3
-
24
-
-
84861784579
-
The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy
-
Westendorp, B. et al. The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy. FASEB J. 26, 2569-2579 (2012).
-
(2012)
FASEB J.
, vol.26
, pp. 2569-2579
-
-
Westendorp, B.1
-
25
-
-
84884486576
-
Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy
-
Costa, M. W. et al. Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy. Circ. Cardiovasc. Genet. 6, 238-247 (2013).
-
(2013)
Circ. Cardiovasc. Genet.
, vol.6
, pp. 238-247
-
-
Costa, M.W.1
-
26
-
-
84880268274
-
Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy
-
Arndt, A. K. et al. Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy. Am. J. Hum. Genet. 93, 67-77 (2013).
-
(2013)
Am. J. Hum. Genet.
, vol.93
, pp. 67-77
-
-
Arndt, A.K.1
-
27
-
-
0031577470
-
A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission
-
Sakai, K. & Miyasaki, J. A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission. Biochem. Biophys. Res. Commun. 237, 318-324 (1997).
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.237
, pp. 318-324
-
-
Sakai, K.1
Miyasaki, J.2
-
28
-
-
0029155706
-
Inducible gene targeting inmice
-
Kuhn, R., Schwenk, F., Aguet, M. & Rajewsky, K. Inducible gene targeting inmice. Science 269, 1427-1429 (1995).
-
(1995)
Science
, vol.269
, pp. 1427-1429
-
-
Kuhn, R.1
Schwenk, F.2
Aguet, M.3
Rajewsky, K.4
-
29
-
-
33846899456
-
Restoration of p53 function leads to tumour regression in vivo
-
Ventura, A. et al. Restoration of p53 function leads to tumour regression in vivo. Nature 445, 661-665 (2007).
-
(2007)
Nature
, vol.445
, pp. 661-665
-
-
Ventura, A.1
-
30
-
-
19944427423
-
Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model
-
Iwasaki, M. et al. Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model. Blood 105, 784-793 (2005).
-
(2005)
Blood
, vol.105
, pp. 784-793
-
-
Iwasaki, M.1
-
31
-
-
33745283008
-
Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation
-
Kawamura-Saito, M. et al. Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation. Hum. Mol. Genet. 15, 2125-2137 (2006).
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 2125-2137
-
-
Kawamura-Saito, M.1
-
32
-
-
0033993821
-
Evi9 encodes a novel zinc finger protein that interacts with BCL6, a known human B-cell proto-oncogene
-
Nakamura, T. et al. Evi9 encodes a novel zinc finger protein that interacts with BCL6, a known human B-cell proto-oncogene. Mol. Cell. Biol. 20, 3178-3186 (2009).
-
(2009)
Mol. Cell. Biol.
, vol.20
, pp. 3178-3186
-
-
Nakamura, T.1
-
33
-
-
10744228125
-
NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function
-
Kuwahara, K. et al. NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function. EMBO J. 22, 6310-6321 (2003).
-
(2003)
EMBO J.
, vol.22
, pp. 6310-6321
-
-
Kuwahara, K.1
|