Biodegradable nanofiber-membrane for sustainable release of lidocaine at the femoral fracture site as a periosteal block: In vitro and in vivo studies in a rabbit model

Colloids and Surfaces B: Biointerfaces

Volumn 140, Issue , 2016, Pages 332-341

  Chou, Ying Chao ^a,b   Cheng, Yi Shiun ^b   Hsu, Yung Heng ^a,b   Yu, Yi Hsun ^a,b   Liu, Shih Jung ^a,b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Biodegradable nanofiber; Periosteal block; Sustainable release of lidocaine

Indexed keywords

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; NANOFIBERS; SURGERY;

ELECTROSPINNING TECHNIQUES; EMBEDDED NANOFIBERS; FEMORAL FRACTURES; LONG BONE FRACTURES; NANOFIBER MEMBRANE; NANOFIBROUS MEMBRANES; PERIOSTEAL BLOCK; SUSTAINABLE RELEASE;

FRACTURE;

ANALGESIC AGENT; LIDOCAINE; NANOFIBER; POLYCAPROLACTONE; ARTIFICIAL MEMBRANE; DELAYED RELEASE FORMULATION; LOCAL ANESTHETIC AGENT;

ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIODEGRADABLE IMPLANT; BODY WEIGHT; DRUG EFFICACY; DRUG IMPLANTATION; DRUG RELEASE; DRUG RESPONSE; ELECTROSPINNING; FEMUR FRACTURE; FLUID INTAKE; FOOD INTAKE; FRACTURE FIXATION; FRACTURE HEALING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; KIRSCHNER WIRE; NONHUMAN; PERIOSTEUM; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; STENT; SUSTAINED DRUG RELEASE; WEIGHT REDUCTION; ANIMAL; ARTIFICIAL MEMBRANE; CHEMISTRY; DELAYED RELEASE FORMULATION; DRINKING; DRUG EFFECTS; EATING; FEMORAL FRACTURES; INFRARED SPECTROSCOPY; INNERVATION; NERVE BLOCK; PAIN, POSTOPERATIVE; PATHOPHYSIOLOGY; PHARMACOKINETICS; PHARMACOLOGY; PROCEDURES; RABBITS AND HARES; SCANNING ELECTRON MICROSCOPY; TIME FACTOR; TREATMENT OUTCOME; ULTRASTRUCTURE;

ABSORBABLE IMPLANTS; ANESTHETICS, LOCAL; ANIMALS; BODY WEIGHT; DELAYED-ACTION PREPARATIONS; DRINKING; DRUG LIBERATION; EATING; FEMORAL FRACTURES; LIDOCAINE; MEMBRANES, ARTIFICIAL; MICROSCOPY, ELECTRON, SCANNING; NANOFIBERS; NERVE BLOCK; PAIN, POSTOPERATIVE; PERIOSTEUM; RABBITS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TIME FACTORS; TREATMENT OUTCOME;

EID: 84954287633     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2016.01.011     Document Type: Article

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